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307 Possible Causes for (6aalpha,6bbeta,12abeta,12balpha) , 5,6,6a,6b,11,12,12a,12b octahydro ,, Dibenzo(a,g)biphenylene 3,9 diol

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  • Alzheimer Disease

    In addition to the APOE locus (encoding apolipoprotein E), 19 loci reached genome-wide significance (P 5 10(-8)) in the combined stage 1 and stage 2 analysis, of which 11[ncbi.nlm.nih.gov] Am J Med 2005 Dec; 118 Suppl. 12A: 48–53 PubMed CrossRef Google Scholar 65. Pappolla MA, Bryant-Thomas TK, Herbert D, et al.[dx.doi.org] In this study, we have tested two major withanamides A (WA) and C (WC) for their ability to protect the PC-12 cells, rat neuronal cells, from beta-amyloid induced cell damage[ncbi.nlm.nih.gov] As expected, selegiline failed to rescue TH levels in 6-month-old Tg2576 mice ( Fig. 6a , Supplementary Fig. 7a ).[dx.doi.org] 1 mg 42 40 0 (3) 7 (5) — — 2 (5) — 3 mg 40 3 (3) 0 (5) — — 8 (5) — 5 mg 39 10 (3) 10 (5) — — 3 (5) — Rogers et al 1998a 6 5 mg 157 153 6 (3) 7 (8) 3 (5) 2 (2) 8 (5) 6 (13)[ncbi.nlm.nih.gov] This was a prospective, single-center, open-label, pilot (proof-of-concept) study, in which 15 patients with mild-to-severe AD were treated for 6 months.[ncbi.nlm.nih.gov] NMDA EPSCs were measured at 4 m m external Ca 2 (except for 2.7 m m in the experiment with MK-801 ( )-5-methyl-10,11-dihydro-5 H -dibenzo [a,d] cyclohepten-5,10-imine hydrogen[doi.org] ((11)C-PIB) ligand was performed.[ncbi.nlm.nih.gov] , 2006 Last Update: January 26, 2007 PET 11C (-)-3-(4-Chlorophenyl)- N '-[(4-[ 11 C]cyanophenyl)sulfonyl]-4-phenyl-4,5-dihydro-1 H -pyrazole-1-carboxamidine [11C]CB1-(-)-12a[web.archive.org] Withanamides in Withania somnifera fruit protect PC‐12 cells from β‐amyloid responsible for Alzheimer's disease Bioactive Natural Products and Phytoceuticals, Department of[dx.doi.org]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro g)biphenylene 3 9 diol
  • Rotavirus

    Gene 11 sequence encodes a nonstructural protein, NSP5 and also encodes NSP6, from an out of phase open reading frame.[doi.org] In the absence of extracellular calcium (culture medium plus 2 mM EGTA), NSP4-EGFP localization was restricted to a diffuse staining pattern (Fig. 12A ).[doi.org] J Clin Microbiol. 2011 Dec;49(12):4382-5. doi: 10.1128/JCM.01303-11. Epub 2011 Oct 12.[ncbi.nlm.nih.gov] As expected, all three proteins showed a diffuse distribution (Fig. 6A , row 5).[jvi.asm.org] Nine estimates of rotavirus positivity were reported among children Figure 6A and 6B ). Figure 5. Percentage of specimens positive for rotavirus by age group. Figure 5.[doi.org] […] rotavirus vaccine adoption by countries, help donors prioritize investments in health interventions, and monitor vaccine impact, we estimated rotavirus mortality for children 5[ncbi.nlm.nih.gov] Strain NT0001 had a genotype constellation of: G3-P[6]-I5-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0042: G4-P[6]-I1-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0077: G4-P[6]-I5-R1-C1-M1-A8[ncbi.nlm.nih.gov] […] in autumn than winter 33 Mexico City Mexico 19N 2233 63 1–12 a 17 13–19 12/99–2/01 76 5 hospitals * Marked increase in fall-winter 34 Pune India 18N 559 70 0.1–17.5 24 20[doi.org] […] correlation was confirmed at the OTU level, where a negative correlation (R    0.464, p  0.005) was found for NoV susceptibility and for the OTU F. prausnitzii_8647 ( Fig. 6B[ncbi.nlm.nih.gov] Cathepsins, endosomal acid proteases, are transported from the trans-Golgi network to late endosomes by the mannose-6-phosphate receptor (M6PR).[ncbi.nlm.nih.gov]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Otitis Media

    Group II included 11 patients (11 ears) without bronchial asthma. Samples of MEE were sent for flow cytometric analysis at initial presentation.[ncbi.nlm.nih.gov] STATEMENT 12a.[doi.org] Types of participants Children up to 12 years of age without AOM.[doi.org] Chronic Suppurative Otitis Media Organism Frequency (%) Comments Acute otitis media Streptococcus pneumoniae* 40 to 50 Most common pathogens are serotypes 19F, 23F, 14, 6B, 6A[aafp.org] Serotypes 6B, 9V, 14, 19A, 19F, and 23F have the highest frequency of penicillin resistance.[web.archive.org] Outcome measures included the number of treatment failures after 5 days, 2 weeks and 6 weeks.[doi.org] The peak incidence occurred at 6 to 12 months of life.[ncbi.nlm.nih.gov] J Clin Microbiol. 2012 Nov;50(11):3809-11. doi: 10.1128/JCM.02051-12. Epub 2012 Sep 12.[ncbi.nlm.nih.gov] Key Action Statement 6A: Clinicians should recommend pneumococcal conjugate vaccine to all children according to the schedule of the Advisory Committee on Immunization Practices[doi.org] Epub 2017 Oct 11.[ncbi.nlm.nih.gov]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Myocardial Infarction

    Four of 11 cohorts had data on cholesterol concentrations.[ncbi.nlm.nih.gov] Crossref Medline Google Scholar 12a. Moran AE, Forouzanfar MH, Roth GA, Mensah GA, Ezzati M, Murray CJL, Naghavi M .[doi.org] Repeat CMR evaluation is planned at 6, 12 and 24 months.[scmr.org] […] analysis of funnel plots suggested the possibility of publication biases in SCD, CV mortality, total/CV hospitalization analyses, with some asymmetries (Figs 5A, 5C and 6A[doi.org] The primary end point was death from coronary heart disease or nonfatal myocardial infarction at 5 years.[ncbi.nlm.nih.gov] In this pilot study, we investigate the potential of circulating miR-208b as a prognostic biomarker of 6-month survival in AMI patients.[ncbi.nlm.nih.gov] Lead EKG ST Elevation tracing color coded.jpg 1.911 1.122; 2,12 MB 12 Lead EKG ST Elevation tracing only.jpg 1.911 1.122; 2,1 MB 12 lead generated anterior MI.JPG 864 350[commons.wikimedia.org] Hashimoto T 1, 2 , Ako J 1, 2 , Nakao K 3 , Ozaki Y 4 , Kimura K 5 , Noguchi T 6 , Yasuda S 6 , Suwa S 7 , Fujimoto K 8 , Nakama Y 9 , Morita T 10 , Shimizu W 11 , Saito Y[ncbi.nlm.nih.gov] The primary end-point was death after 5 years.[ncbi.nlm.nih.gov] Lead EKG ST Elevation tracing color coded.jpg 1 911 1 122; 2,12 MB 12 Lead EKG ST Elevation tracing only.jpg 1 911 1 122; 2,1 MB 12 lead generated anterior MI.JPG 864 350[commons.wikimedia.org]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Multiple Sclerosis

    Neurol 62(11):2058–2064 CrossRef Google Scholar 20.[dx.doi.org] -fold at only a small number of gene loci, including zinc finger and bric-a-brac, tramtrack (BTB) domain containing protein 20 ( Zbtb20 ) and tripartite motif-containing 12A[ncbi.nlm.nih.gov] -12 doses), and new T 1 -weighted hypointense lesions (thrice-daily BG-12) (nominal P Conclusions In patients with relapsing–remitting multiple sclerosis, BG-12 (at both doses[doi.org] Statement 6a Clinicians should evaluate barriers to adherence to DMT in people with MS (Level B).[doi.org] 4 (5.4%) and 5 (3.5%).[dx.doi.org] , Sonalee Agarwal 6 , Jessica Kong 6 , Annie Zhang 6 , Vissia Viglietta 6 , Sarah I Sheikh 6 , Emily Seidman 7 , Katherine T Dawson 6 1 Neuroscience Institute, Virginia Mason[dx.doi.org] The percentage of all phase hypointense lesions, visible on corresponding FLAIR images, was significantly higher in active RR-MS compared to SP-MS (33.8% vs. 6.8%; Fig. 6A[doi.org] ., S1 Pyramidal cells from Layer 6b) then summed to get the values for grouped cell types (i.e., S1 Pyramidal cells).[doi.org] Through 5 years, 75.1% of patients were free of 6-month CDW; 42.9% achieved 6-month CDI.[ncbi.nlm.nih.gov] BG-12 group).[doi.org]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Pediatric Crohn's Disease

    Bailey A 7 , Friedman ES 8 , Hoffmann C 7 , Albenberg L 3 , Sinha R 7 , Compher C 9 , Gilroy E 2 , Nessel L 2 , Grant A 4 , Chehoud C 7 , Li H 2 , Wu GD 10 , Bushman FD 11[ncbi.nlm.nih.gov] Figure 11b Figure 12a Sinus tracts.[doi.org] […] and interleukin‐23 (IL‐12/23p40).[doi.org] By contrast, the Ad5.HAV-prime/MVA.HAV-boost protocol in naïve mice ( Figure 6A ) resulted in substantial IgG antibody recognition of rec.AhpC and rec.Mpa.[doi.org] Google Scholar Crossref Medline ISI 5. Jones, J, Loftus, EV, Panaccione, R.[doi.org] , 25 , 6 , (401) , (2002) .[www3.interscience.wiley.com] METHODS: Retrospective chart review was conducted in 11 pediatric patients with CD who initiated the SCD as therapy at time of diagnosis or flare.[ncbi.nlm.nih.gov] […] the course of the disease, which is consistent with evidence in the recent literature about the influence of psychological distress on CD activity. 264, 266 ECCO Statement 12A[doi.org] METHODS: Our prospective study involved 51 children with conventional therapy resistant, severe CD (mean age: 15.25years, range: 11-18years).[ncbi.nlm.nih.gov] Of the 17 remaining strains, 10 invaded epithelial cells to a similar degree as LF82 ( Figure 6a ).[dx.doi.org]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Bronchiolitis

    The objective was to evaluate the association between IL-17A rs2275913 (-197G A) polymorphism and post-bronchiolitis asthma and/or allergic rhinitis in a prospective 11-13[ncbi.nlm.nih.gov] When alcohol-based rubs are not available, individuals should wash their hands with soap and water (Evidence Quality: B; Recommendation Strength: Strong Recommendation). 12a[doi.org] The upper age limit of bronchiolitis cannot be 24 months and that limit should be 12 months [ 1 ], or even lower [ 2 , 5 ].[erj.ersjournals.com] Hoeppner T 1 , Borland M 1, 2 , Babl FE 3, 4, 5 , Neutze J 6 , Phillips N 7, 8, 9 , Krieser D 4, 5, 10 , Dalziel SR 11, 12 , Davidson A 4, 5, 13 , Donath S 4, 5 , Jachno K[ncbi.nlm.nih.gov] For in vivo study, tracheas from BALB/c or C57BL/6 donors were transplanted into C57BL/6 recipients to create a HTT model.[ncbi.nlm.nih.gov] METHODS: For this observational study, we recruited 213 consecutive infants with bronchiolitis (cases: median age: 2 months; age range: 0.5-12 months; boys: 55.4%) and 213[ncbi.nlm.nih.gov] Lupo J 1 , Schuffenecker I 2 , Morel-Baccard C 3 , Bardet J 4 , Payen V 4 , Kaiser L 5 , Constant S 6 , Lobrinus JA 7 , Lin-Marq N 7 , Lina B 2 , Morand P 8 , Tapparel C 5[ncbi.nlm.nih.gov] Lung. 2015 Dec;193(6):1051-4. doi: 10.1007/s00408-015-9817-4. Epub 2015 Oct 7.[ncbi.nlm.nih.gov] No case of bacteremia was reported in 8 of 11 studies. No case of meningitis was reported in any of the studies.[ncbi.nlm.nih.gov] Oakley E 1, 2, 3 , Brys T 1 , Borland M 4, 5 , Neutze J 6 , Phillips N 7, 8, 9 , Krieser D 2, 3, 10 , Dalziel SR 11, 12 , Davidson A 2, 3, 13 , Donath S 2, 3 , Jachno K 2[ncbi.nlm.nih.gov]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Escherichia Coli

    The strains exhibited 36 different virulence patterns, of which 11, referred to as UP (UPEC pattern) 1 to UP 11 were most common.[ncbi.nlm.nih.gov] […] human-pathogenic V. cholerae serogroups (O1 and O139) have evolved by sequential acquisition of two key fitness factors: the toxin-coregulated pilus (TCP) and cholera toxin (CT) (Fig. 12A[mmbr.asm.org] […] research on E . coli K‐12.[doi.org] Two independent fed-batch runs yielded similar levels of glycoprotein as found in LB shake flask cultures after a total cultivation time of 25 h (Figures 6A and 6B ).[doi.org] KEYWORDS: Carbapenem-resistant; Egypt; Escherichia coli; NDM-5; New Delhi metallo-β-lactamase 5; Sequence type [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov] It's also important that they follow a process that enforces best practices, so that the CMS itself is training your team with every post as they onboard. 6.[news.discovery.com] Subcategories This category has the following 11 subcategories, out of 11 total.[commons.wikimedia.org] Valleau D 1 , Little DJ 2 , Borek D 3, 4 , Skarina T 1 , Quaile AT 1 , Di Leo R 1 , Houliston S 5, 6 , Lemak A 5, 6 , Arrowsmith CH 5, 6 , Coombes BK 2 , Savchenko A 7, 8[ncbi.nlm.nih.gov] JAPANESE JOURN AL OF APPLIED PHYSICS PART 2 LETTERS. 2001;40(6A):561-563. 47. Ireland JC, Klostermann P, Rice EW, Clark RM.[researchgate.net] European Union funding: For a three-year period (2018-12-11 to 2021-12-10), EPPO has been awarded an EU grant for the further development of the EPPO code system (agreement[gd.eppo.int]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Familial Hypercholesterolemia

    We report a case of FH in an 11-year-old boy who presented with multiple xanthomas at both elbows, thickened Achilles tendons, and hyperplasia of the intima-media complex[ncbi.nlm.nih.gov] Deficiency 2 Peroxisome biogenesis disorder 10A (Zellweger) 3 Peroxisome biogenesis disorder 11A (Zellweger) 3 Peroxisome biogenesis disorder 11B 3 Peroxisome biogenesis disorder 12A[preventiongenetics.com] Abstract We present the case of a 12-year-old girl with familial hypercholesterolemia and coronary artery disease.[ncbi.nlm.nih.gov] […] factor-α G( 376)A 0.011 G( 308)A 0.178 G( 244)A 0.001 G( 238)A 0.039 Tumor necrosis factor-β (lymphotoxin alpha) Thr26Asn 0.350 Metalloproteinase 3 (stromelysin-I) ( 1171) 5A/6A[doi.org] J Clin Lipidol. 2016 Sep-Oct;10(5):1262-5. doi: 10.1016/j.jacl.2016.05.005. Epub 2016 May 14.[ncbi.nlm.nih.gov] […] to 10 mg (age, 6- P values were adjusted for age, sex, carotid artery site, and family relations.[ncbi.nlm.nih.gov] Ex 11-12 deletion was linked to the c.2140 5G A mutation.[ncbi.nlm.nih.gov] Here we report on the finding of a seldom exon 7-12 duplication in the low-density lipoprotein receptor gene of three Danish patients with FH.[ncbi.nlm.nih.gov] Fig. 5.[doi.org] J Atheroscler Thromb. 2018 Jun 1;25(6):539-553. doi: 10.5551/jat.CR002. Epub 2018 Feb 6.[ncbi.nlm.nih.gov]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol
  • Crohn's Disease

    Corresponding rates at Week 52 were 31% and 11% (absolute risk reduction [ARR]: 19.7%; 95% CI, -8.9 to 46.2).[ncbi.nlm.nih.gov] Figure 11b Figure 12a Sinus tracts.[doi.org] Ustekinumab (CNTO 1275) and briakinumab (ABT-874) are monoclonal antibodies that target the standard p40 subunit of the cytokines interleukin-12 and interleukin-23 (IL-12[ncbi.nlm.nih.gov] Here are 5 common signs to look out for, some more expected than others. (Heal your whole body with Rodale's 12-day liver detox for total body health .)[prevention.com] J AAPOS. 2017 Dec;21(6):512-514. doi: 10.1016/j.jaapos.2017.07.218. Epub 2017 Nov 2.[ncbi.nlm.nih.gov] All patients were regularly monitored for 5 years, and clinical recurrence was defined as CDAI   150.[ncbi.nlm.nih.gov] […] the course of the disease, which is consistent with evidence in the recent literature about the influence of psychological distress on CD activity. 264, 266 ECCO Statement 12A[doi.org] Of the 17 remaining strains, 10 invaded epithelial cells to a similar degree as LF82 ( Figure 6a ).[nature.com] The specific IgG total antibody responses in low and high dose MAP infected Ad5-prime/MVA-boost vaccinated mice are shown in Figure 6B .[doi.org] Abstract Interleukin 6 (IL6) is an inflammatory cytokine; signaling via its receptor (IL6R) is believed to contribute to development of inflammatory bowel diseases (IBD).[ncbi.nlm.nih.gov]

    Missing: (6aalpha 6bbeta 12abeta 12balpha) 12b octahydro Dibenzo(a g)biphenylene 3 9 diol