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6,355 Possible Causes for (C C, 8, Chemokine, Ligand, Motif)

  • Influenza

    Cytokine and chemokine quantification To determine levels of cytokine or chemokine proteins in lung, at each time point examined three mice from each group were exsanguinated[doi.org] HA ligand binds the virus to the cell to bring about infection.[ncbi.nlm.nih.gov] Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) Reviewed - Annotation score: - Experimental evidence at protein level i Pathology & Biotech i Chemistry databases PTM[uniprot.org] All segments for C/628, C/660, and C/729 were closely related to C/OK.[doi.org] […] onset (8 of 8 patients) more often than with granulocytopenia (2 of 8 patients) or monocytopenia (2 of 8 patients).[doi.org]

  • Urinary Tract Infection

    Prakash Nagarkatti - Cannabinoid receptor antagonists in the treatment of obesity Mitzi Nagarkatti - Gut microbiome in obesity Udai Singh – Chemokines and chemokine receptors[pathmicro.med.sc.edu] […] infection Conflict of interest statement Conflict of interest statement: J.W.J. and S.J.H. are inventors on US patent US8937167 B2, which covers the use of mannoside-based FimH ligand[ncbi.nlm.nih.gov] Here are 8 of the most common causes of urinary tract infections—and a handful of helpful tips for prevention.[prevention.com] Cystitis ‎ (7 F) E Emphysematous cystitis ‎ (2 C) N Nitrituria ‎ (3 F) P Pyelonephritis ‎ (2 C, 5 F) Pyuria ‎ (1 C, 11 F) R Renal tuberculosis ‎ (2 C) U Urethritis ‎ (1 C[commons.wikimedia.org] The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection . mBio 3 , e00177[doi.org]

  • Osteoporosis

    Monocytes are important sources of cytokines and chemokines, are involved in immune system functions and have been related to bone metabolism.[doi.org] Osteoporos Int. 2015 Jan;26(1):415-8. doi: 10.1007/s00198-014-2852-9. Epub 2014 Aug 20.[ncbi.nlm.nih.gov] […] levels of the following markers of bone turnover: Beta-Crosslaps, osteocalcin, bone alkaline phosphatase, osteoprotegerin and receptor activator for nuclear factor kappa-B ligand[ncbi.nlm.nih.gov] Here we describe skeletal findings in 4 boys from 2 families with mutations in PLS3 (c.994_995delGA; p.Asp332* in family 1; c.1433T   C; p.Leu478Pro in family 2).[ncbi.nlm.nih.gov] The phosphate motifs in bisphosphonates have a similar conformation to inorganic pyrophosphate (PPi), the natural substrate of TNSALP; thus, treatment with bisphosphonates[ncbi.nlm.nih.gov]

  • Streptococcal Infection

    This effect leads to activation of other cell types, as well as significant cytokine/chemokine release.[clinicaladvisor.com] Abstract An 8-year-old girl died suddenly without prior symptoms.[ncbi.nlm.nih.gov] […] syndrome (mean age: 11.0 3.0 years; 10 males), and 15 normal adults (mean age: 28.7 7.9 years; 8 males) underwent dynamic PK PET imaging and binding potential, a measure of ligand-TSPO[ncbi.nlm.nih.gov] More than 5 million C. More than 10 million D. More than 20 million 2. How are GAS infections spread? A. Saliva B. Nasal discharge C. Infected skin wound D.[urmc.rochester.edu] GBS pilus island 2’ includes the genes encoding PilB, an LP(x)TG-motif-containing protein that polymerises to form a pilus backbone, and accessory pilus proteins PilA and[intechopen.com]

  • Human Herpesvirus 8

    Gov't MeSH terms Animals Binding, Competitive CHO Cells Cell Line, Tumor Chemokine CCL2/genetics Chemokine CCL2/metabolism* Chemokine CXCL12/metabolism Chemokines/genetics[ncbi.nlm.nih.gov] Name [ modifica ] Human gammaherpesvirus 8 Acronym: HHV-8 Synonym [ modifica ] Kaposi's sarcoma-associated herpesvirus (KSHV) References [ modifica ] ICTV Virus Taxonomy 2015[species.wikimedia.org] Lebbe C 1 , Porcher R , Marcelin AG , Agbalika F , Dussaix E , Samuel D , Varnous S , Euvrard S , Bigorie A , Creusvaux H , Legendre C , Frances C ; Skin and Organ Transplantation[ncbi.nlm.nih.gov] […] vIRF-1 and vIRF-4 USP7 binding sequences in association with USP7 have been reported; both involve interactions with N-terminal-domain residues of USP7 via EGPS and ASTS motifs[ncbi.nlm.nih.gov] […] chemistry Lectins, C-Type/genetics Lectins, C-Type/metabolism* Protein Binding Protein Structure, Tertiary Receptors, Cell Surface/chemistry Receptors, Cell Surface/genetics[ncbi.nlm.nih.gov]

  • Hepatitis G

    As down-regulation of CC chemokine receptor 5 (CCR5) delays HIV progression, we investigated whether CCR5 expression is altered by exposure of lymphocytes to HGV proteins.[ncbi.nlm.nih.gov] , T P Leary , G J Dawson , S M Desai , G G Schlauder , A S Muerhoff , J C Erker , S L Buijk , M L Chalmers Proceedings of the National Academy of Sciences Apr 1995, 92 (8)[doi.org] Longer survival in HIV-positive individuals is associated with high serum concentrations of ligands for CCR5 (RANTES [regulated on activation, normal T-cell expressed and[ncbi.nlm.nih.gov] C (GBV-C) Hepatitis G Virus (HGV) GB virus C (GBV-C): Hepatitis G virus (HGV ), which is now better known as HB virus C (GBV-C ) is a positive-strand RNA containing virus[authorstream.com] Amino acid sequence analysis of this large polyprotein reveals the presence of protease, helicase, and replicase motifs.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm

    Keywords: Inflammation, cancer, cytokines, chemokines, macrophages Abstract: Inflammatory conditions in selected organs increase the risk of cancer.[doi.org] Enhanced antigen-specific anti-tumor immunity with altered peptide ligands that stabilize the MITC-peptide-TCR complex . Immunity 13 , 529–538 (2000). 36.[doi.org] The location was within the right sinonasal tract in 54% of cases, the left sinonasal tract in 38% of cases, and not reported in 8% of cases.[ncbi.nlm.nih.gov] Gonzalez, C.[doi.org] ChIp-IT Express kit (Active Motif, ) was used for ChIp experiments.[doi.org]

  • Rhinovirus

    Previously we and others have shown that a variety of cytokines and chemokines were induced by both HRV 14 and/or HRV 16 infection in vitro that include FGF-Basic, chemokines[journals.plos.org] IL-6 and IL-8 release the most (p 0.05).[ncbi.nlm.nih.gov] KEYWORDS: TRAIL; asthma; inflammation; rhinovirus; tumor necrosis factor-related apoptosis-inducing ligand [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov] RV-C wheezing illnesses.[ncbi.nlm.nih.gov] These revealed conserved motifs; clade-specific diversity, including a potential newly identified species (HRV-D); mutations in field isolates; and recombination.[ncbi.nlm.nih.gov]

  • Idiopathic Pulmonary Fibrosis

    Most of the proposed biomarkers belong to chemokines (IL-8, CCL18), proteases (MMP-1 and MMP-7), and growth factors (IGBPs) families.[link.springer.com] METHODS: Repetitive 24-h respiratory polygraphies (RP) and pulmonary function tests were performed at baseline and after 3, 4, 7 and 8 months.[ncbi.nlm.nih.gov] Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis.[doi.org] ] vs C 0.68 [95% CI, 0.61-0.73]; P .001) and the Chicago cohort (C 0.73 [95% CI, 0.62-0.78] vs C 0.69 [95% CI, 0.59-0.75]; P .01).[ncbi.nlm.nih.gov] Previous work from our laboratory has demonstrated that Toll-like receptor 9 (TLR9), a pathogen recognition receptor that recognizes unmethylated CpG motifs in bacterial and[stm.sciencemag.org]

  • Adult T-Cell Leukemia - Lymphoma

    A new anti-CC chemokine receptor 4 monoclonal antibody (mogamulizumab) has been shown to be effective for ATLL.[ncbi.nlm.nih.gov] A total of 8 courses of mogamulizumab were administered, which resulted in CR.[ncbi.nlm.nih.gov] Programmed cell death ligand 1 (PD-L1) is expressed on both tumor and tumor-infiltrating nonmalignant cells in lymphoid malignancies.[ncbi.nlm.nih.gov] Mogamulizumab is a new defucosylated humanized monoclonal antibody agent which targets C-C chemokine receptor type 4 (CCR4) expressed occasionally on the surface of ATL cells[ncbi.nlm.nih.gov] Treatment options for acute ATL patients include chemotherapy, stem cell transplantation, and recently the anti-chemokine (C-C motif) receptor 4 antibody, although most patients[ncbi.nlm.nih.gov]