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  • Primary Central Nervous System Lymphoma

    My life was literally changed overnight by brain tumors.[braintumor.org] In contrast, the intensive NHL-BFM treatment might reduce the rate of relapse but also selects for resistant disease at relapse.[haematologica.org] […] of Korea. 5 Department of Radiation Oncology, Yonsei Cancer Center, 50-1 Yonsei-ro, Seodaemoon-gu, Seoul, 03722, Republic of Korea. 6 Department of Radiation Oncology, Inha[ncbi.nlm.nih.gov] Clinical Advances in Hematology & Oncology July 2015, Volume 13, Issue 7 Tracy Batchelor, MD, MPH Executive Director Stephen E. and Catherine Pappas Center for Neuro-Oncology[hematologyandoncology.net] Abstract Primary Central nervous system lymphoma (PCNSL) is most frequently a diffuse large B cell lymphoma (DLBCL), which is confined to the Central nervous system (CNS).[ncbi.nlm.nih.gov] Author information 1 Department of Haematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany. 2 Department of Clinical[ncbi.nlm.nih.gov] Blood 88 : 252 Camilleri-Broet, S., F. Davi, J. Feuillard, D. Seilhean, J. F. Michiels, P. Brousset, B. Epardeau, E. Navratil, K. Mokhtari, C. Bourgeois, et al 1997 .[jimmunol.org] BACKGROUND: Here we describe a case of PCNSL which was located peripherally as a single lesion and showed no evidence of pathological findings of lymphoma at the first biopsy[ncbi.nlm.nih.gov] KEYWORDS: R-IDARAM; diffuse large B-cell lymphoma; primary central nervous system lymphoma; stereotactic brachytherapy[ncbi.nlm.nih.gov] The aim of this study was to investigate the feasibility of reduced-dose WBRT for patients who achieved PR.[ncbi.nlm.nih.gov]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Californium and
  • Atypical Teratoid Rhabdoid Tumor

    Commonly misdiagnosed over the decades as primitive neuroectodermal tumor of the brain, it has dramatically different biological behavior.[ncbi.nlm.nih.gov] The objective response rate observed after RT was 38%. The 2-year progression-free and overall survival rates are 53% /- 13% and 70% /- 10%, respectively.[ncbi.nlm.nih.gov] As most patients with AT/RT present as infants or young children, radiation therapy has been a less than standard treatment option.[ncbi.nlm.nih.gov] , Psycho-Oncology , 22 , 2 , (447-458) , (2012) .[doi.org] Clinical and morphological features of an apparently unique, biologically aggressive central nervous system tumor in 32 infants and children are presented.[ncbi.nlm.nih.gov] KEYWORDS: Central Nervous System; Child; Drug Therapy; Radiotherapy; Rhabdoid Tumor; Stem Cell Transplantation[ncbi.nlm.nih.gov] Hyung‐Ihl Kim, Myung‐Ja Jeong and Ha‐Young Choi , Atypical teratoid/rhabdoid tumor of the central nervous system: Clinico‐pathological study , Neuropathology , 22 , 4 , (252[doi.org] Giving high-dose chemotherapy before an autologous peripheral blood stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them.[clinicaltrials.gov] We present here a rare case of an adult (35 years) low-grade SMARCB1-deleted brain tumor with transition into prototypical AT/RT over 14 years.[ncbi.nlm.nih.gov] Brachytherapy 13 (2): 196-202, 2014 Mar-Apr.[cancer.gov]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Californium and
  • Ependymoma

    Ependymomas can grow in different parts of the brain, and symptoms may relate to the area of the brain that is affected: A tumour of the frontal lobe of the brain may cause[melissasfightingfund.co.uk] rate with 33% (0%) remaining stable.[springerlink.com] Recent advances in neuroimaging, neurosurgery and radiation therapy have improved disease control and functional outcomes for children with ependymoma, including children[ncbi.nlm.nih.gov] This was a prospective, multicenter Phase II trial conducted through the Children's Oncology Group (ClinicalTrials.gov Identifier NCT01462695 ).[ncbi.nlm.nih.gov] Abstract We present the first case of central neurocytoma with a component suggesting ependymal-like differentiation as an unclassified glioneuronal tumor.[ncbi.nlm.nih.gov] EMX2 promotes symmetric division (in embryonic stem cells) that distributes the apical membrane equally to the two daughter cells, resulting in stem cell proliferation.[doi.org] VENTRICLE, CEREBELLUM) / CEREBELLUM ICD-Morpho 9391/3 Ependymoma, NOS Atlas_Id 5016 Phylum Central Nervous system::Ependymoma WHO/OMS Classification Central Nervous system[atlasgeneticsoncology.org] Median follow-up was 108 months (range, 24 to 252 months). RESULTS: The 5-, 10-, and 15-year overall survival rates were 71.5%, 63.3%, and 55.4% .[aboutcancer.com] Abstract Superficial siderosis of the central nervous system is a syndrome caused by deposition of hemosiderin in the subpial layers of the central nervous system, occurring[ncbi.nlm.nih.gov] Due to the presence of giant cells, the differential diagnosis of other primary neoplasias at that site were considered, including paraganglioma, malignant peripheral nerve[ncbi.nlm.nih.gov]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Californium and
  • Glioma

    If the brain scan suggests a brain tumor, a biopsy may be performed for diagnosis.[webmd.com] Observed survival rates were 42.4% at 6 months, 17.7% at one year, and 3.3% at 2 years.[ncbi.nlm.nih.gov] KEYWORDS: 1H-MRS; Posttreatment radiation effect; Proton magnetic resonance spectroscopy; Radiation necrosis; Recurrent glioma; Tumor recurrence[ncbi.nlm.nih.gov] Oncology Group; and U10 CA37422 to Community Clinical Oncology Programs.[jco.ascopubs.org] BACKGROUND: Primary central nervous system (CNS) histiocytic sarcoma is an extremely rare lymphoproliferative disorder that affects the CNS and behaves aggressively.[ncbi.nlm.nih.gov] You are here Home Types of Cancer Brain Stem Glioma - Childhood Brain Stem Glioma - Childhood This is Cancer.Net’s Guide to Brain Stem Glioma - Childhood.[cancer.net] VENTRICLE, CEREBELLUM) / CEREBELLUM ICD-Morpho 9380/3 Glioma, malignant Atlas_Id 5763 Phylum Central Nervous system::Glioma WHO/OMS Classification Central Nervous system Note[atlasgeneticsoncology.org] Prognostic significance of IDH1 and IDH2 mutations in cholangiocarcinoma In the Fudan cohort of 252 patients with follow-up data, the presence of IDH1 or IDH2 mutation was[doi.org] This study was conducted to explore whether peripheral blood inflammatory markers combined with radiologic features could predict proliferation potency.[ncbi.nlm.nih.gov] We retrospectively review our experience in 25 patients with pathologically proven low grade gliomas (LGG) treated with protracted low dose temozolomide to primarily quantify[springerlink.com]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Californium and
  • Glioblastoma Multiforme

    Glioblastomas belong to a group of brain tumours known as gliomas, as they grow from a type of brain cell called a glial cell.[thebraintumourcharity.org] Incidence Rates Incidence rates for histologic subtypes of CNS tumors are not readily available, since most cancer registries give combined data for all brain tumors.[doi.org] Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys 32(4): 931–941 PubMed Google Scholar 64.[springerlink.com] Li , Downregulated miR‐17, miR‐29c, miR‐92a and miR‐214 may be related to BCL11B overexpression in T cell acute lymphoblastic leukemia , Asia-Pacific Journal of Clinical Oncology[doi.org] Chicago, IL: Central Brain Tumor Registry of the United States; 1997–2001. Google Scholar 2. Landis SH, Murray T, Bolden S, Wingo PA: Cancer statistics .[doi.org] Cancer stem cells from Glioblastoma Multiforme tumors express markers that are also expressed in non-cancerous neural stem cells, including nestin and Sox2.[ncbi.nlm.nih.gov] We report a case of massive PE treated with systemic thrombolysis in a patient with recent neurosurgery for an intracranial neoplasm.[ncbi.nlm.nih.gov] nervous system (CNS) in humans.[tpx.sagepub.com] Cranial computed tomography (CT) and magnetic resonance imaging (MRI) were obtained, showing a heterogeneous lesion in the cingulate gyrus, with peripheral and central areas[ncbi.nlm.nih.gov] Patients with high and low expression of BTAT10 had median survival times of 335 and 485 d, respectively (HR 1.298, 95% CI 1.0881–1.548, p 0.00374) ( Fig 6B ).[journals.plos.org]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Californium and
  • Astrocytoma

    Sometimes the nature of the seizures can help determine the location of the brain tumor .[cedars-sinai.edu] The morbidity rate and mortality rate improves significantly with the early diagnosis and the prompt removal of the tumor.[symptoma.com] Alterations in the methylation profiles of cell cycle regulating genes may control cell response to radiation.[ncbi.nlm.nih.gov] From Wikibooks, open books for an open world Radiation Oncology This page may need to be reviewed for quality.[en.wikibooks.org] Abstract Central nervous system tumors are relatively common in the United States, with more than 40,000 cases annually.[ncbi.nlm.nih.gov] A stem cell marker, CD133, was reported to predict recurrence patterns in intracranial glioblastoma.[ncbi.nlm.nih.gov] VENTRICLE, CEREBELLUM) / CEREBELLUM ICD-Morpho 9400/3 Astrocytoma, NOS Atlas_Id 5007 Phylum Central Nervous system::Glioma WHO/OMS Classification Central Nervous system Note[atlasgeneticsoncology.org] Seyfried , Metastasis , Cancer as a Metabolic Disease , (215-252) , (2012) . Thomas N.[doi.org] On magnetic resonance imaging, a contrast-enhanced tumor in the left occipital lobe with peripheral edema was noted.[ncbi.nlm.nih.gov] low-grade gliomas.[danafarberbostonchildrens.org]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Californium and
  • Radiation Therapy

    See the image below for an example of the placement of an LDR tandem and ovoid.[emedicine.medscape.com] KEYWORDS: Brain; Cognition; Radiosensitivity; Radiotherapy; Toxicity[ncbi.nlm.nih.gov] The 3-, 5- and 7-year local relapse-free survival rates were 100%, 100% and 95%, respectively.[ncbi.nlm.nih.gov] " radiation.[en.wikipedia.org] The Department of Radiation Oncology is part of Heidelberg University's Faculty of Clinical Medicine .[umm.uni-heidelberg.de] PURPOSE: To examine safety and efficacy of stereotactic body radiation therapy (SBRT) for centrally located hepatocellular carcinoma (CL-HCC).[ncbi.nlm.nih.gov] The cancer stem cells are left behind. Plus, the radiation actually turns normal cells into cancer stem cells.[thetruthaboutcancer.com] This paper presents a magnetic position tracking system for radiation therapy. The proposed system uses only four transmitting coils and an implantable transponder.[ncbi.nlm.nih.gov] Author information 1 Department of Radiation Oncology, Taipei Medical University Hospital, Taipei, Taiwan No. 252, Wu Hsing Street, Taipei City 110, Taiwan. 2 Department of[ncbi.nlm.nih.gov] BACKGROUND: Schwannomas and meningiomas are relatively common tumors of the nervous system.[ncbi.nlm.nih.gov]

    Missing: (Cf 252) @ @ @ @ @ Californium and
  • Breast Irradiation

    One hundred patients were accrued from 1997 to 2000; 98 were evaluable; 65 underwent HDR and 33 LDR MCT. Median age was 62 years; 88% had T1 tumors; 81% were pN0.[ncbi.nlm.nih.gov] With a median follow-up of 38.5 months (range: 8 - 49 months), no patients had a local recurrence, but one patients with triple negative disease had a distant metastases in brain[degruyter.com] CONCLUSIONS: APBI with interstitial multi-catheter brachytherapy was associated with good outcomes, low relapse and toxicity rates.[ncbi.nlm.nih.gov] One of the nation’s first and most experienced intraoperative radiation therapy (IORT) programs, pioneering same-day surgery and radiation treatment.[stanfordhealthcare.org] The Department of Radiation Oncology offers a partial breast treatment technique sometimes referred to as MammoSite Breast Brachytherapy.[nyp.org] SEARCH METHODS: We searched the Cochrane Breast Cancer Group Specialized Register (4 May 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (2015, Issue 5[ncbi.nlm.nih.gov] Cancer cells are generally less differentiated and more stem cell -like; they reproduce more than most healthy differentiated cells, and have a diminished ability to repair[en.wikipedia.org] Set-up accuracy was comparable with other prone systems; residual errors need further investigations.[ncbi.nlm.nih.gov] METHODS AND MATERIALS: From 1999 to 2007, 2173 patients were treated with breast-conserving surgery and IORT (21 Gy/1 fraction) as the sole local treatment: 252 patients with[ncbi.nlm.nih.gov] […] year results of accelerated partial breast irradiation (APBI) using image-guided intensity-modulated radiotherapy (IG-IMRT) following breast conserving surgery (BCS) for low-risk[ncbi.nlm.nih.gov]

    Missing: (Cf 252) @ @ @ @ @ Californium and
  • Neuroblastoma

    Therefore, honokiol may be a potential candidate drug for treating brain tumors.[ncbi.nlm.nih.gov] The 5-year rates for overall (OS) and event-free survival are 37 and 32%, respectively.[ncbi.nlm.nih.gov] KEYWORDS: Galectin-1; neuroblastoma; radiation response[ncbi.nlm.nih.gov] Seeger 7 Department of Experimental Oncology, St. Jude Children's Research HospitalMemphis, TN Search for other works by this author on: A.[doi.org] Abstract Neuroblastoma is the most common, non-central nervous system tumor of childhood. It has the potential to synthesize catecholamines.[ncbi.nlm.nih.gov] Gradual improvements in survival have correlated with therapeutic intensity, and the ability to harvest, process and store autologous hematopoietic stem cells has allowed[ncbi.nlm.nih.gov] Recurrent: While not formally part of the staging system, this term is used to describe cancer that has come back (recurred) after it has been treated.[ochsner.org] […] chemoresistant neuroblastoma subtypes to MAPK-targeted treatment correlates with ERK, p53 expression, and signaling response to U0126 , Journal of Pediatric Surgery , 41 , 1 , (252[doi.org] VENTRICLE, CEREBELLUM) / CEREBELLUM ICD-Morpho 9500/3 Neuroblastoma, NOS Atlas_Id 5002 Phylum Central Nervous system::Neuroblastoma WHO/OMS Classification Central Nervous[atlasgeneticsoncology.org] In addition, loss of whole chromosome 4 was over-represented in low-stage (1-2) and low-risk tumours.[doi.org]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Californium and
  • Medulloblastoma

    It usually starts in the 4th ventricle region of the brain.[floridaproton.org] Parents rated patients' attentional and social functioning.[ncbi.nlm.nih.gov] The risk of clinically relevant HL was shown when D mean exceeds 45 Gy independent of radiation technique or radiation regime.[ncbi.nlm.nih.gov] From Wikibooks, open books for an open world Radiation Oncology ‎ Medulloblastoma This page may need to be reviewed for quality.[en.wikibooks.org] Kepner;Patricia Duffner;Larry Kun;Elizabeth Perlman; Checking for direct PDF access through Ovid Abstract Fifty-five patients with atypical teratoid/rhabdoid tumors of the central[doi.org] However, the metabolic properties of medulloblastoma stem cells, and whether specific metabolic pathways are essential for sustaining their stem cell-like phenotype and radioresistance[ncbi.nlm.nih.gov] system Disease Medulloblastomas are malignant invasive embryonal tumours of the cerebellum with a tendency to metastasize in the central nervous system (CNS).[atlasgeneticsoncology.org] Neurosurgery, University of Ulsan, Asan Medical Center, Seoul 05505, South Korea. 33 Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa 252[ncbi.nlm.nih.gov] Histologically, 5-ALA-intense biopsies from inner areas were characterized by a significant amount of cancer cells, whereas 5-ALA faint regions from peripheral areas displayed[ncbi.nlm.nih.gov] @gmail.com. 3 Department of Oncology, University Children's Hospital, Zürich, Switzerland. 4 Department of Radiation Oncology, University Hospital Zürich, Zurich, Switzerland[ncbi.nlm.nih.gov]

    Missing: (Cf 252) (LDR) @ @ @ @ @ Brachytherapy Californium and