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18 Possible Causes for (CoA acetylating), 2 oxidoreductase, pyruvate:ferredoxin

  • Acetyl-CoA Carboxylase Deficiency

    An important gene associated with Acetyl-Coa Carboxylase Deficiency is ACACA (Acetyl-CoA Carboxylase Alpha).[malacards.org] […] oxidoreductase, alpha subunit [EC: 1.2.7.7 ] K00187 2-oxoisovalerate ferredoxin oxidoreductase, beta subunit [EC: 1.2.7.7 ] K00189 2-oxoisovalerate ferredoxin oxidoreductase[genome.jp] In yeast, acetyl-CoA synthetase delivers acetyl-CoA to histone acetyltransferases for histone acetylation.[en.wikipedia.org]

  • Trichomonas Vaginalis

    The only other eukaryotic succinate-dependent acetyl-CoA-transferase identified so far is in Trypanosoman brucei .[en.citizendium.org] Two hydrogenosomal proteins, pyruvate ferredoxin oxidoreductase (PFOR) and ferredoxin, play a critical role in the reductive activation of metronidazole.[ncbi.nlm.nih.gov] Characterization of a fourth type of 2-keto acid-oxidizing enzyme from a hyperthermophilic archaeon: 2-ketoglutarate ferredoxin oxidoreductase from Thermococcus litoralis[nature.com]

  • Mycobacterium Smegmatis

    (PTA)-mediated conversion of acetyl-phosphate to acetyl-CoA; (ii) acetyl-CoA synthetase (ACS)-mediated 1 conversion of acetate to acetyl-CoA through an acetyl-AMP intermediate[mcponline.org] ferredoxin reductase, putidaredoxin/putidaredoxin reductase, and peroxides (H 2 O 2 and t-butyl hydroperoxide).[ncbi.nlm.nih.gov] In Table S3, the GO term corresponding to ‘integral to membrane’ is over-represented in d 1, oxidoreductase and acyl-CoA dehydrogenase activity in d 2, and proteins involved[omicsonline.org]

  • Mitochondrial Disease

    PDC is located in the mitochondrial matrix and irreversibly decarboxylates pyruvate to acetyl CoA.[aasmnet.org] Abstract Apoptosis-inducing factor mitochondrion-associated 1 (AIFM1), encoded by the gene AIFM1 , has roles in electron transport, apoptosis, ferredoxin metabolism, reactive[ncbi.nlm.nih.gov] These 13 subunits include 7 subunits of NADH dehydrogenase, 1 subunit of ubiquinol-cytochrome c oxidoreductase, 3 subunits of cytochrome c oxidase, and 2 subunits of ATP synthase[circ.ahajournals.org]

  • Acidaminococcus

    All CoA-transferases share a common mechanism in which the CoA moiety is transferred from a donor (e.g. acetyl CoA) to an acceptor, (R)-2-hydroxyglutarate, whereby acetate[ncbi.nlm.nih.gov]  Gram-negative anaerobic straight, curved, and helical rod アシダミノコッカス属 Acidaminococcus 関連語: クロトニルCoA ( crotonyl-CoA ) ブチリルCoA脱水素酵素 ( butyryl-CoA dehydrogenase ) フェレドキシン ( ferredoxin[lsd.bioscinet.org] Locher KP, Hans M, Yeh AP, Schmid B, Buckel W, Rees DC: Crystal structure of the Acidaminococcus fermentans 2-hydroxyglutaryl-CoA dehydratase component A.[karger.com]

  • Micrococcus Luteus

    Actin-like ATPase domain 16 15 5 2 SCOP 48179 6-phosphogluconate dehydrogenase C-terminal domain-like 15 15 10 3 SCOP 52374 Nucleotidylyl transferase 15 15 5 1 SCOP 56801 Acetyl-CoA[supfam.org] 3 3 2 0 SCOP 52343 Ferredoxin reductase-like, C-terminal NADP-linked domain 3 3 3 0 SCOP 50156 PDZ domain-like 3 1 1 0 SCOP 55979 DNA clamp 3 3 1 0 SCOP 81923 Double Clp-N[supfam.org] 1 SCOP 102114 Radical SAM enzymes 6 6 2 1 SCOP 53254 Phosphoglycerate mutase-like 6 6 4 1 SCOP 51395 FMN-linked oxidoreductases 6 6 3 0 SCOP 52266 SGNH hydrolase 6 6 4 0 SCOP[supfam.org]

  • Isolated Succinate-CoQ Reductase Deficiency

    Which combination of cofactors is involved in the conversion of pyruvate to acetyl-CoA?[quizlet.com] While the levels of the transcripts for the plastid enzymes Gln synthetase ( GLN2 ), ferredoxin-dependent Glu synthase (Fd-GOGAT; GLU1 ), and nitrite reductase ( NiR ) and[plantphysiol.org] , derived from the β-oxidation pathway via the electron transfer flavoprotein (ETF) and the ETF-CoQ oxidoreductase system ( Fig. 99-1 ).[ommbid.mhmedical.com]

  • Atypical HSD10 Disease

    These isomers 3-hydroxyvaleric acid and 3-oxovaleric acid were found, which may be products of the condensation of propionyl-CoA with acetyl-CoA catalyzed by 3-oxoacyl-CoA[pubfacts.com] The purified enzyme was shown to be active in the presence of NADPH , spinach ferredoxin, and spinach ferredoxin-NADP -oxidoreductase.[vanderbilt.edu] This message will disappear when the data is sorted. (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD oxidoreductase Also acts, more slowly, on (2S,3S)-2-hydroxy-3-methylpentanoyl-CoA[brenda-enzymes.org]

  • Methanobacterium Extroquens

    The fourth substrate cycle was observed between malate and (acetyl-CoA glyoxylate).[bmcsystbiol.biomedcentral.com] The use of a pyruvate formate lyase instead of ferredoxin-oxoacid (pyruvate ferredoxin oxidoreductase (Deku_0030–0033), which is not more abundant when grown with lactate,[nature.com] […] gene: "MLCB1450.07"; product: "putative TREMBLNEW:MLCB1450_7 rv0440 00 530723 530295 groEL2 60 kD chaperonin 2 M.leprae 65 kd antigen, complete cds.[cdfd.org.in]

  • Homocystinuria without Methylmalonic Aciduria Type cblE

    […] carboxylase (ACCase), (EC 6.4.1.2), generates malonyl-CoA, ADP, and Pi from Acetyl-CoA, C02, and ATP.[google.de] […] oxidoreductase subunit beta89.70 6369523 Glov_3720Glov_3720proteinpyruvate flavodoxin/ferredoxin oxidoreductase domain protein PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase[ecogene.org] An epsilonproteobacterial complex I mediates the electron transfer from ferredoxin to the quinone pool.[nature.com]