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7,976 Possible Causes for (DNA), 180kDa, II, beta, human, protein,, topoisomerase

Show results in: Italiano

  • Morganella Morganii

    (APACHE II) scores (p[ncbi.nlm.nih.gov] […] of cell lysates by sodium dodecyl sulphate-discontinuous polyacrylamide gel electrophoresis, strains could be differentiated into 21 types on the basis of outer membrane proteins[ncbi.nlm.nih.gov] DNA-DNA hybridization studies and phenotypic characterizations revealed that M. morganii can be separated into three DNA relatedness groups and seven biogroups.[ncbi.nlm.nih.gov] The occurrence of mutations in DNA gyrase (gyrA and gyrB) and topoisomerase IV (parC,parE) genes was also investigated in this strain.[ncbi.nlm.nih.gov] Abstract Morganella morganii is a facultative Gram-negative anaerobe present in the human gastrointestinal system as normal flora.[ncbi.nlm.nih.gov] Abstract The effect of salicylate, a marRAB inducer, on the resistance to beta-lactams was characterized in an AmpC beta-lactamase hyperproducer Morganella morganii clinical[ncbi.nlm.nih.gov] The protein patterns, which contained 45 to 50 discrete bands, were highly reproducible.[ncbi.nlm.nih.gov]

    Missing: 180kDa
  • Novobiocin

    […] novobiocin-elicited proteolysis of Topo II and the PMA-induced Topo II phosphorylation, as well as the decrease in Topo II activity and the acquisition of differentiation[ncbi.nlm.nih.gov] BACKGROUND: Heat shock protein 90 (Hsp90) interacts with and stabilizes several oncogenic protein kinases (e.g., p185(erbB2), p60(v-src), and Raf-1) and is required for the[ncbi.nlm.nih.gov] […] fork, but it, too, has no influence on DNA repair.[ncbi.nlm.nih.gov] Targets Topoisomerase II [1] Topoisomerase IV [1] In vitro Novobiocin also interacts with Hsp90, altering the affinity of the chaperone for geldanamycin and radicicol and[selleckchem.com] CONCLUSIONS: The obtained data indicate that novobiocin may induce death of human gingival fibroblasts.[ncbi.nlm.nih.gov] We have purified the major yeast novobiocin binding proteins and identified one of them as the beta-subunit of the yeast mitochondrial F1 ATP synthetase, a protein highly[ncbi.nlm.nih.gov] All of the Aeromonas isolates detected on blood agar were also detected on ABA, and 89% of the Aeromonas isolates detected on these media were beta-hemolytic.[ncbi.nlm.nih.gov]

    Missing: 180kDa
  • Poison

    Abstract Drugs capable of trapping topoisomerase II (Top2), an essential enzyme that cleaves DNA to remove naturally occurring knots and tangles, can serve as potent anticancer[ncbi.nlm.nih.gov] Further, increased B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation activated NRF2 signaling in KB-7D cells.[ncbi.nlm.nih.gov] DNA relaxation assays and DNA cleavage and relegation assays were performed and showed a higher potential to interact with topoisomerase I (Topo I) and topoisomerase II (Topo[ncbi.nlm.nih.gov] RESULTS: In 2015, 2,792,130 closed encounters were logged by NPDS: 2,168,371 human exposures, 55,516 animal exposures, 560,467 information calls, 7657 human confirmed nonexposures[ncbi.nlm.nih.gov] Examples include: Beta blockers: Beta blockers are a class of drugs used to treat heart conditions (for example, angina , abnormal heart rhythms ) and other conditions, (for[emedicinehealth.com] CONTEXT: In October 2014, the Drug Enforcement Administration reclassified hydrocodone to schedule II, increasing regulations on use.[ncbi.nlm.nih.gov] Other Appearances Beyond the Final Fight series, Poison was planned to appear in the cancelled Capcom Fighting All-Stars ; though not playable in the beta test of the game[streetfighter.wikia.com]

    Missing: 180kDa
  • Gastrodia

    In DNA topoisomerase I and II inhibition assays in vitro at a concentration of 20 microM, 1 showed potent inhibitory activity, 66% and 71% inhibition, respectively, compared[ncbi.nlm.nih.gov] A retardation assay was applied to measure protein aggregation during Htt expression.[ncbi.nlm.nih.gov] MATERIALS AND METHODS: Human dopaminergic SH-SY5Y cells were used to demonstrate the protective effects of GE against multiple parameters such as MPP( )-induced cell viability[ncbi.nlm.nih.gov] Amyloid beta-peptide stimulates neuronal cell death, but the underlying signaling pathways are poorly understood.[ncbi.nlm.nih.gov] II. Government Printer, Wellington. Thorsen, M. J.; Dickinson, K. J. M.; Seddon, P. J. 2009. Seed dispersal systems in the New Zealand flora.[nzpcn.org.nz] Glutamate (GLU) induced DNA fragmentation, a hallmark of apoptosis, in a dose-dependent manner.[ncbi.nlm.nih.gov] Curr Sci 12:13–17 Google Scholar Swamy BGL (1949) Embryological studies in the Orchidaceae II. Embryology.[as-botanicalstudies.springeropen.com]

    Missing: 180kDa
  • Salmonella Enteritidis

    Three periods were compared, namely (i) before implementation of vaccination (2000-2004), (ii) during voluntary vaccination (2005-2006) and (iii) during implementation of[ncbi.nlm.nih.gov] Salmonella spp. possess effector proteins that display biochemical activities and modulate host functions.[ncbi.nlm.nih.gov] KEYWORDS: Colorimetric detection; DNA aptamer; Salmonella Enteritidis[ncbi.nlm.nih.gov] The analysis of point mutations in type II topoisomerase genes and the detection of plasmid-mediated quinolone resistance genes showed that all but two harbored a gyrA mutation[ncbi.nlm.nih.gov] Human cases were interviewed, clusters were investigated, and a case-control study was conducted.[ncbi.nlm.nih.gov] IL-12 receptor beta 1 (IL-12Rβ1) deficiency, the most common form of MSMD, is associated with weakly virulent mycobacteria and salmonella.[ncbi.nlm.nih.gov] Abstract An HIV-infected man receiving antiretroviral therapy-who also had lupus-like vasculitis and membranous glomerulonephritis (treated with prednisolone and azathioprine), beta-thalassaemia[ncbi.nlm.nih.gov]

    Missing: 180kDa
  • Giardia Lamblia

    Topo II has typical ATPase and DNA cleavage activity of type II topoisomerases.[ncbi.nlm.nih.gov] Pax proteins are important regulators of development and cell differentiation in Drosophila and vertebrates.[ncbi.nlm.nih.gov] Since these isolates, A and B, are of human origin, anthroponotic transmission of Giardia can be suggested for the route of infection in this region.[ncbi.nlm.nih.gov] The use of monoclonal antibodies against beta giardin indicated ventral disc localization, particularly at the periphery in WB trophozoites.[ncbi.nlm.nih.gov] There are many protein ligands and/or drugs described with very different affinity to a large number of target proteins or receptors.[ncbi.nlm.nih.gov] This is the first time that MLST has been used to characterise G. lamblia isolates in human clinical samples from Rio de Janeiro.[ncbi.nlm.nih.gov] Approximately 1 week after treatment all samples tested negative, indicating rapid clearance of parasitic DNA after successful treatment. 2014 The Authors Clinical Microbiology[ncbi.nlm.nih.gov]

    Missing: 180kDa
  • Trichinella Spiralis

    DNase II homologs were also identified in non-metazoan species.[ncbi.nlm.nih.gov] A recombinant MCD-1 protein expressed as a GST-fusion protein in Escherichia coli failed to inhibit papain in vitro suggesting that the T. spiralis protein is a new member[ncbi.nlm.nih.gov] […] administration & dosage Vaccines, DNA/genetics Vaccines, DNA/immunology Substances Antibodies, Helminth Cytokines Vaccines Vaccines, DNA Pyrophosphatases nudix hydrolases[ncbi.nlm.nih.gov] T. spiralis antigens that share epitopes with human autoantigens were identified by assessing the cross-reactivity of autoantibody-containing serum samples with T. spiralis[ncbi.nlm.nih.gov] OBJECTIVES: We evaluated whether the effectiveness of albendazole against encapsulated larvae increases when 2-hydroxypropyl-beta-cyclodextrin (HP-betaCD) is added to improve[ncbi.nlm.nih.gov] ATP synthase F1, beta subunit (ATPase; 0.58 and 0.51) and serine protease precursor (Spp; 0.42 and 0.65) were down-regulated in both bile-activated and cell-cultured larvae[ncbi.nlm.nih.gov] Abstract Three cases of human infection by Trichinella spiralis were first confirmed by detecting encysted larvae in the biopsied muscle in December 1997, in Korea.[ncbi.nlm.nih.gov]

    Missing: 180kDa topoisomerase
  • Morus

    Activity was determined by using a type II diabetic rat model.[ncbi.nlm.nih.gov] Abstract An organic layer prepared from the Chinese crude drug 'Sang-Bai-Pi' (Morus root bark) was studied in order to identify the inhibitory compounds for protein tyrosine[ncbi.nlm.nih.gov] Although B[a]P is a procarcinogen, enzymatically metabolized benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE) could intercalate into DNA to form bulky BPDE-DNA adducts as[ncbi.nlm.nih.gov] MeOH extracts reduced the level of topoisomerase IIα but increased the level of p27(Kip1), with no significant effect on p21(Cip1/waf1).[ncbi.nlm.nih.gov] Abstract Mulberry leaf is commonly used for sericulture in almost every part of the world but its potential to be utilized for human consumption is not well recognized.[ncbi.nlm.nih.gov] […] compounds [beta-sitosterol, beta-sitosterol-3-O-beta-glucopyranoside, ursolic acid, moracin M (1), kaempferol-3-O-beta-glucopyranoside and quercetin-3-O-beta-glucopyranoside[ncbi.nlm.nih.gov] This compound showed potent cytotoxic activity (IC(50) 1.7 microM) on the cells, and potent inhibitory activity on topoisomerase II (IC(50) 22.8 microM).[ncbi.nlm.nih.gov]

    Missing: 180kDa
  • Toxic Effect

    Abstract To evaluate the biological effects of wastewater samples containing heavy metals, the effects of metal Cd (II) and As (V) were studied on Spirodela polyrrhiza L.[ncbi.nlm.nih.gov] OBJECTIVE: To investigate the toxicity of tannic acid related compounds such as gallic acid and polyphenol on the activity of plasma proteins in vitro.[ncbi.nlm.nih.gov] The degree of DNA damage including the percentage of tail DNA, tail length and Olive tail moment (OTM) were markedly aggravated.[ncbi.nlm.nih.gov] To assess the capability of HR, we measured the cellular sensitivity to camptothecin (topoisomerase I poison) and olaparib (poly(ADP ribose)polymerase inhibitor) because these[ncbi.nlm.nih.gov] Arsenic, nickel, and lead were selected for mixtures exposed to A549 human lung cancer cells.[ncbi.nlm.nih.gov] […] used being classically toxic to rodent adult beta-cells.[ncbi.nlm.nih.gov] Abstract A 10 year-old female patient presented to the outpatient unit of the ophthalmology department of Menelik II Hospital with complaints of inward deviation of the left[ncbi.nlm.nih.gov]

    Missing: 180kDa
  • Malignant Glioma

    We suggest "new" response criteria for phase II studies of supratentorial malignant glioma and favor rigorous criteria similar to those in medical oncology, with important[jco.ascopubs.org] Citrullinated proteins were identified by mass spectrometry.[ncbi.nlm.nih.gov] In immunohistochemical tests, most of the tumor cells in these cases were negative for O6-methylguanine-DNA methyltransferase, which antagonizes the effect of DNA-alkylating[ncbi.nlm.nih.gov] A newly synthesized Indeno[1,2-c]quinoline derivative, which has previously been found to potentially trap DNA-topoisomerase cleavage complexes more effectively than camptothecin[ncbi.nlm.nih.gov] MIRN17 microRNA, human MicroRNAs RNA, Long Noncoding RNA, Untranslated 5-hydroxymethylcytosine 5-Methylcytosine Grant support P30 CA023168/CA/NCI NIH HHS/United States[ncbi.nlm.nih.gov] Abstract Combined treatment with interferon-beta, MCNU (Ranimustine), and radiotherapy was assessed in patients with malignant glioma who had not received previous cytotoxic[ncbi.nlm.nih.gov] This Phase II, prospective, matched controlled, multicenter trial was conducted to assess the safety and efficacy of aglatimagene besadenovec (AdV-tk) plus valacyclovir (gene-mediated[ncbi.nlm.nih.gov]

    Missing: 180kDa