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2,190 Possible Causes for (MMHCC), , , Beta, Cell, Cell, Endocrine, Islet, Langerhans, Pancreas, of

  • Echovirus

    KEYWORDS: acinar cells; echovirus; enterovirus; inflammation; islet of Langerhans; pancreas; tropism[] E4 did not cause any effects on cell lysis, however it was able to replicate in 2 out of 7 islet donors. Beta-cell function was hampered in all infected islets (P[] By contrast, E4 replicated in all examined insulinoma cells with no apparent cell destruction.[] Diabetes-associated autoimmunity was evaluated by measurement of several islet cell related autoantibodies.[] Thus, after attachment to the same cell surface receptor, these closely related viruses enter the same cells by different mechanisms.[] These monoclonal antibodies, which prevented virus attachment to specific receptor sites, recognized the alpha and beta subunits of the integrin VLA-2 (alpha 2 beta 1), a[] Generally, TRIO acts as a key component in the regulation of axon guidance and cell migration.[] This study aimed to investigate the capability of echovirus strains to infect human exocrine and endocrine pancreatic cells.[] Human islets from non-diabetic donors (n 7) were infected with the virus strains E4, E16 and E30, all isolated from patients with aseptic meningitis who seroconverted to islet[]

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  • Toxoplasma Gondii

    Pathological examination revealed the presence of T. gondii zoites adjacent to the islets of Langerhans and in pancreatic parenchyma of acutely infected mice.[] School of Medicine, Jinan University, Guangzhou, 510632, China. 2 Department of Epidemiology, School of Medicine, Jinan University, Guangzhou, 510632, China. 3 Department of Endocrine[] She had had pancreas transplantation 2 years previously and had recently completed a course of antirejection medication.[] All patients who transmitted T. gondii showed significant changes in the mean levels of immune cells.[] Abstract Genetic and pathologic data suggest that amyloid beta (Aβ), produced by processing of the amyloid precursor protein, is a major initiator of Alzheimer's disease ([] Direct activation of STAT3 by the parasite enhance anti-inflammatory function of IL-10 and TGF beta.[] Furthermore, we assessed the immune response of the primary macrophages by long-term investigation of gene expression of IL-1 beta, IL-12p40, Lipopolysaccharide induced TNF-alpha[] By contrast, Toxoplasma-specific T-cell responses were activated by HLA-DR molecules (presumably present on antigen-presenting cells).[] […] in a cell type-dependent manner.[]

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  • Islet Cell Tumor

    […] that the amyloid protein from insulinoma is derived from islet amyloid polypeptide (or amylin) that is produced by tumor cells originating from beta cells of the islet of Langerhans[] BACKGROUND: Islet cell tumor (ICT) metastasis is one of the potentially lethal outcomes of multiple endocrine neoplasia type 1 (MEN 1).[] Islet cell tumors are a collective group of neoplasms that arise from the islet cells of the pancreas.[] You are here Home Types of Cancer Neuroendocrine Tumor of the Pancreas Neuroendocrine Tumor of the Pancreas This is Cancer.Net’s Guide to Neuroendocrine Tumor of the Pancreas[] It is a rare syndrome caused by non-beta cell islet-cell tumors (gastrinomas) located in or in proximity to the pancreas.[] Other names for a pancreatic islet cell tumor are: islet of Langerhans tumor pancreatic endocrine tumor neuroendocrine tumor Islet cell tumors can be either nonfunctional[] Alternative Names Islet cell tumors; Islet of Langerhans tumor; Neuroendocrine tumors Causes, Incidence, and Risk Factors In the normal pancreas, cells called islet cells[] Abstract A case of multiple nonfunctional pancreatic islet cell tumor in multiple endocrine neoplasia type I (MEN I) is reported.[] Abdominal computed tomography showed multiple cysts in the whole pancreas and a calcified solid mass in the pancreatic head.[]

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  • Pheochromocytoma-Islet Cell Tumor Syndrome

    Pheochromocytoma and islet cell tumor are endocrine neoplasms that may occur in families harboring mutations leading to von Hippel-Lindau disease (VHL), multiple endocrine[] Marcador principal Enfermedad mayor Otras patologías AFP Carcinoma hepatocelular primario Teratoblastoma de ovario y testículo -HCG Tumores pituitarios ß2M Neoplasia de células beta[] Similarly, surgery is the main treatment of islet cell tumors.[] Mieloma múltiple, linfoma de células beta, leucemia linfocítica crónica, enf. de Waldenström CA 15.3 Cáncer de mama Varios carcinomas CA 19.9 Cáncer gástrico y pancreático[] PICT patients may present with an islet cell tumor of the pancreas, with pheochromocytoma, or both.[] […] crecimiento insulino simil-1 PSA: antígeno prostático específico VIP:péptido intestinal vasoactivo SCC: antígeno de carcinoma de células escamosas IL-2: interleuquina 2 ß2M: beta[] Similarly, surgery is the main treatment of islet cell tumors.[] In any case, signs and symptoms correspond to the local and systemic effects of the endocrine neoplasms.[] PICT patients may present with an islet cell tumor of the pancreas, with pheochromocytoma, or both.[]

    Missing: (MMHCC) Langerhans of
  • Enterovirus Infection

    To this end, we studied the response of human islets of Langerhans upon mock or CVB3 infection.[] Autopsy reports have shown that interferon-α was expressed on the surface of beta cells, but not other islet endocrine cells, in patients who died soon after diagnosis of[] CONCLUSIONS/INTERPRETATION: The results show a definite islet-cell tropism of enteroviruses in the human pancreas.[] Mice pancreas samples were provided and submitted by the JDRF nPOD-Virus Group (under ethical approvement R13028).[] These infections appeared to be temporally related to increased percentage of V beta 7 gene transcripts.[] […] infections cause or enhance inflammation in genetically predisposed individuals, triggering an interferon (IFN) response and the upregulation of MHC-I molecules in pancreatic endocrine[] No CXCL10 was expressed in exocrine pancreas. Serum levels of CXCL10 were increased.[] Non-diabetic mothers who had islet autoantibodies (n 365) against glutamic acid decarboxylase (GADA), islet antigen-2 autoantibodies (IA-2A), or insulin autoantibodies (IAA[] […] primary endothelial cells.[]

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  • Nesidioblastosis

    […] examination of the pancreas revealed that the cause of hyperinsulinemic hypoglycemia was nesidioblastosis characterized by the presence of enlarged, irregular islets of Langerhans[] Abstract A patient is described in whom a small 0.8-mm-diameter endocrine tumor was found in association with localized pancreatitis, stricture of the main pancreatic duct[] Isolated nesidioblastotic islets showed an increased basal rate of insulin secretion (nesidioblastotic islets, 81.3 /- 6.4 vs. control islets, from cadaveric organ normal[] Key Words: Pancreas ; Persistent neonatal hypoglycemia ; Nesidioblastosis ; Pathogenesis[] These findings may be related to local tissue hypoxia and/or increased metabolic energy needs in sickle cell disease.[] Among the various indicators of islet changes, beta-cell hypertrophy characterized by enlarged and hyperchromatic beta-cell nuclei was the most significant and diagnostic[] It is caused by hypertrophy and hyperplasia of the islands of Langerhans, and can lead to persistent hyperinsulinemic hypoglycemia.[] We describe a report of adult nesidioblastosis in association with a pancreatic endocrine microadenoma.[] The endocrine microadenoma and nesidioblastosis stained for insulin, suggesting both likely contributed to hypoglycemia.[]

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  • Calcitonin

    The neuroimmune dialogue between peripheral neurons and Langerhans cells (LCs) within mucosal epithelia protects against incoming pathogens.[] BACKGROUND: Although pancreatic endocrine tumor can produce a variety of hormones, few pancreatic tumors produce a high systemic calcitonin concentration.[] Abstract Verner-Morrison syndrome, characterized by diarrhea, hypokalemia, and hypochlorhydria, is caused most commonly by vasoactive intestinal polypeptide-secreting islet[] Investigation revealed hypercalcemia, hyperphosphatemia, hypercalcitonemia and a well-defined mass in the head of the pancreas on CT scan.[] In all patients, complete remission of the giant cell granuloma was observed, without signs of recurrence.[] METHODS: The expression of CT, transforming growth factor-beta 1(TGF-β1) and bone morphogenetic protein (BMP) in gingival crevicular fluid (GCF) was measured by ELISA.[] Abstract We present an unusual case of a 52-year-old woman with severe, uncontrollable, refractory diarrhea attributable to pancreatic endocrine carcinoma (ECA) with markedly[] Islet amyloid polypeptide (IAPP) [ PMID: 2407732 ] (also known as diabetes-associated peptide (DAP), or amylin) is a peptide of 37 amino acids that selectively inhibits insulin-stimulated[] KEYWORDS: amyloid beta-peptides; aromatic interactions; crystal structures; iodination; peptides[]

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  • Graft Rejection

    الصفحة 37 - An electron microscope study of basal melanocytes and high-level clear cells (Langerhans cells) in vitiligo. ‏[] ) lost their grafts because of chronic rejections, and 2 patients still had impaired endocrine function.[] In Group2, with an increased number of transplanted islets in the presence of BMX-001, more healthy insulin-positive islet masses were obtained at biopsy and necropsy (4 weeks[] […] solitary pancreas recipients.[] KEYWORDS: FFPE kidney biopsies; chronic T cell-mediated rejection; effector memory T cells; transcriptomics[] Beta-catenin balances immunity. Science 329: 767-769.[] Although the surgical expertise for the transplantation of skin, kidneys, heart, lungs, liver, spleen, bone marrow, and endocrine organs is now well in hand, it outpaces thus[] Islet transplantation has been hampered by inefficient islet isolation techniques, which are timeconsuming and yield low islet numbers from each donor pancreas.[] The heterogeneity of the monocyte/macrophage lineage cells could be one of the reasons why these cells have been neglected up to now.[]

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  • Ischemic Stroke

    Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis characterized by a xanthogranulomatous infiltration of tissues by spumous histiocytes.[] K ATP channels mediate insulin secretion in pancreatic islet beta cells, and controlling vascular tone.[] […] to assist the cell-based therapy.[] Treatment for thyroid storm with beta-blocker, glucocorticoid, and potassium iodide-iodine was started and MR venography was performed on hospital day 3 for further evaluation[] KEYWORDS: Ischemic stroke; Mesenchymal stem cells; Stem cells; Transplantation[] Meandering of the left temporal artery (TA) with induration and high inflammatory responses (white blood cell count 22,500 per microliter, C-reactive protein 35.0 mg/dL, and[] Abstract ATP-sensitive potassium (K ATP ) channels are ubiquitously expressed on the plasma membrane of cells in multiple organs, including the heart, pancreas and brain.[] However, ischemia-induced spontaneous neurogenesis is not suffcient, thus cell-based therapy, including infusing exogenous stem cells or stimulating endogenous stem cells[] In the field of regenerative medicine, mesenchymal stem cells (MSCs) have an increasingly prominent position due to their advantages of multiple differentiation, low immunogenicity[]

    Missing: (MMHCC) Endocrine of
  • Theophylline

    Abstract In vitro research in the field of type I diabetes is frequently limited by the availability of a functional model for islets of Langerhans.[] Therefore, theophylline causes havoc to body’s endocrine system (a network of biochemical signaling systems integrated by hormones) that is necessary for maintaining bone[] Acta Diabetologica Latina (1989) 24-h blood glucose pattern in type I and type II diabetics after oral treatment with pentoxifylline as assessed by artificial endocrine pancreas[] […] for gene- and cell-based therapies in the future.[] Abstract It has been proposed that beta-blocker therapy reverses metabolic and cardiovascular disorders in acute theophylline poisoning.[] Many patients with chronic obstructive pulmonary disease continue to experience significant functional limitation despite the use of both long-acting anticholinergic and beta-agonist[] Of these, 29 study arms included an active control, such as adrenaline, beta-2 agonists, or leukotriene receptor antagonists, and 23 study arms compared theophylline (with[] Here we show that MTX and caffeine and theophylline differentially affect a motogenic T-cell mechanism driven by endogenous thrombospondin-1 (TSP-1) and its receptor, low[] In this study, we observed that TINCR was up-regulated in bladder cancer tissues and cells and contributed to oncogenesis and cancer progression.[]

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