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685 Possible Causes for (MPO ANCA), Antibody, Antineutrophil, Cytoplasmic, Determination, Myeloperoxidase, Reagents

Did you mean: (MPO ANCA), antimony, Antineutrophil, Cytoplasmic, Determination, Myeloperoxidase, Reagents

  • Microscopic Polyangiitis

    Abstract To clarify the roles of neutrophils in anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitic neuropathy, we studied neutrophil extracellular traps[] Anti-neutrophil cytoplasmic antibodies (ANCA) appear to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV).[] Contributed reagents/materials/analysis tools: HW LS WT. Wrote the paper: HW LS. References 1. Ozen S, Ruperto N, Dillon MJ, Bagga A, Barron K, Davin JC, et al.[] We recently demonstrated that the abnormal formation and impaired degradation of neutrophil extracellular traps (NETs) may be crucially involved in the generation of myeloperoxidase[] PURPOSE: To determine mortality and its predictive factors in elderly Japanese patients with severe microscopic polyangiitis (MPA).[] […] with microscopic polyangiitis on the basis of the cardinal symptoms of the condition, including rapidly progressive glomerulonephritis and the presence of myeloperoxidase-antineutrophil[] DISCUSSION: The present case suggests that the mycoplasma infection triggered the elevation of MPO-ANCA titer and provoked glomerulonephritis in a patient with MPO-ANCA positive[]

  • Renal Vasculitis

    Abstract Few studies have reported on the long-term prognosis of anti-neutrophil cytoplasmic antibody (ANCA)-negative renal vasculitis.[] Contributed reagents/materials/analysis tools: TTM YMH CW MC. Wrote the paper: TTM YMH CW MC MHZ. References 1.[] Here, serum BAFF and APRIL levels were investigated to analyze their association with disease activity in myeloperoxidase anti-neutrophil cytoplasmic autoantibody (MPO-ANCA[] Multivariate Cox regression model was used to determine the independent predictors of mortality.[] Abstract We report the first case of renal antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis treated with autologous mesenchymal stromal cells (MSCs).[] Here, we describe a patient with MPO-ANCA-associated vasculitis, presenting with pulmonary-renal syndrome.[] Abstract To evaluate the efficacy of cytapheresis for the treatment of rapidly progressive glomerulonephritis (RPGN) caused by myeloperoxidase antineutrophil cytoplasmic antibody[]

  • Rapidly Progressive Glomerulonephritis

    Serological examination revealed positive antineutrophil cytoplasmic autoantibodies (ANCA) against proteinase 3 (Pr3) and myeloperoxidase (MPO).[] […] anti-neutrophil cytoplasmic antibodies (MPO-ANCA; 66 EU).[] All patients had a high titer of serum autoantibodies against myeloperoxidase (MPO-ANCA) when the diagnosis of RPGN was made.[] BACKGROUND: To determine whether intravenous immunoglobulin (IVIg) can control disease activity in patients with myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA[] Abstract The course of rapidly progressive glomerulonephritis (RPGN) caused by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is often life-threatening,[] The myeloperoxidase-ANCA test result was negative. The patient was treated with ursodeoxycholic acid (600 mg/day) and had been stable for 6 years.[] LIMITATIONS: Although the primary result was statistically significant, there is insufficient statistical information to reliably determine whether plasma exchange decreases[]

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  • Pauci-Immune Glomerulonephritis

    AIM: A significant proportion of pauci-immune glomerulonephritis (PIGN) patients are reported to have absence of anti-neutrophilic cytoplasmic antibodies (ANCA).[] The lack of ANCA antibodies may indicate a variation in clinical presentation and outcomes of this disease.[] Among the PICGN patients, 62.5% had a positive ANCA test, 80% had myeloperoxidase-ANCA and 20% had proteinase-3-ANCA.[] We determined to evaluate the prevalence and clinical significance of immune deposits in ANCA-associated GN.[] Subsequent renal biopsy demonstrated a focal necrotising pauci-immune glomerulonephritis and a diagnosis of MPO-ANCA-associated microscopic polyangiitis was made.[] ANCA against myeloperoxidase were present. Anti-double-stranded DNA, ANA, and anti-histone antibodies were positive. Serum complements were normal.[] The goal of our study was to apply the proposed classification system to a United States cohort of vasculitis patients and determine the association of IWGRP class with estimated[]

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  • Granulomatosis with Polyangiitis

    […] antineutrophilic cytoplasmic antibodies (c-ANCAs).[] The authors described the characteristics of antineutrophil cytoplasmic antibody -negative GPA with CNS onset in a patient and discussed on its management, which may contribute[] All 3 patients had elevated levels of serum myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA), but not proteinase 3-ANCA.[] This study aimed to determine whether patients at risk for relapse can be distinguished based on increased in vitro autoantibody production.[] Abstract Recent findings have indicated a close relationship between myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-positive hypertrophic pachymeningitis and[] OBJECTIVES: We applied the ACR/EULAR 2017 provisional classification criteria for granulomatosis with polyangiitis (GPA) to 150 Korean patients with previously diagnosed antineutrophil[] Her history of recurrent asthma exacerbations, eosinophilia, recurrent sinus infections and positive myeloperoxidase antibodies was suggestive of eosinophilic granulomatosis[]

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  • Immune Complex–Mediated Small Vessel Vasculitis

    Small vessel vasculitis is divided into immune complex-mediated vasculitis and pauci-immune vasculitis associated with, and probably caused by, anti-neutrophil cytoplasmic[] Cryoglobulinaemia, anticardiolipin antibodies, antinuclear antibodies, hepatitis C virus antibodies and hepatitis B virus surface antigen were normal or negative.[] However, only antibodies to myeloperoxidase have been convincingly associated with vasculitis.[] The ratio of antibody to antigen determines the solubility of ICs.[] ELISA or EIA assay tests identify enzyme targets within the neutrophils, such as PR3-ANCA or MPO-ANCA.[] (ANCA anti-neutrophilic cytoplasmic antibodies) Information from references 1 – 3 . What are ANCA?[] Thorough history and examination are essential to determine if symptoms and signs are confined to the skin, or if there may be systemic involvement, and to determine a cause[]

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  • Systemic Vasculitis

    Treatment for Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Table 2.[] Serum ANCA against myeloperoxidase (MPO) turned positive. Repeated kidney biopsy showed more severe lesion than last time.[] Evaluating the exact extension of the systemic features determines the choice of treatment.[] Antimyeloperoxidase antibodies (MPO)-ANCA and antiproteinase 3 antibodies (PR3)-ANCA were strongly positive.[] RESULTS: The patient showed a high titer of pANCA (myeloperoxidase-ANCA). She then developed scleritis in the left eye and multiple gastric ulcers.[] […] vasculitis, a systematic MedLine search has been performed.Most of the data analyzed have confirmed that lung involvement seems to develop more frequently in patients with myeloperoxidase-ANCA-positive[] […] surveillance of the vasculature by leucocytes that sense microbial or sterile threats to vessel integrity and initiate protective responses that entail most events that determine[]

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  • Propylthiouracil

    We report a case of perinuclear antineutrophil cytoplasmic antibody-associated vasculitis developed during treatment with PTU for Grave's disease. The Author(s) 2014.[] INTRODUCTION: Increasing evidence has suggested that linear epitopes of antineutrophil cytoplasmic antibody (ANCA) directed to myeloperoxidase (MPO) might provide clues to[] Antineutrophil cytoplasmic antibody against myeloperoxidase (MPO-ANCA) was positive, and she was diagnosed with PTU-induced vasculitis.[] A half-fractional factorial design was employed for screening to determine the variables significantly affecting the extraction efficiency.[] We studied tissue histology and carried out MPO-ANCA subtype analysis by immunofluorescence and flow cytometry and MPO-ANCA epitope analysis.[] Abstract Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) refers to a group of potentially life-threatening autoimmune diseases.[] A highly positive perinuclear pattern of antineutrophil cytoplasmic antibody with specificities for IgM myeloperoxidase was observed.[]

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  • Glomerulonephritis

    BACKGROUND: Immunopathologic features predict renal function at baseline and follow-up in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis (GN).[] […] reaction for antinuclear antibody ( 320), hematuria, and massive proteinuria (3.33 g/day).[] Chemical Screening of Urine by Reagent Strip 1.5 continuing education credit hours (based on 1505 customer ratings) Red Blood Cell (RBC) Morphology 2 continuing education[] PURPOSE: In this retrospective study with case-control design, we aimed to determine the clinical and pathological characteristics of post-transplant glomerulonephritis (GN[] Abbreviations HCV: hepatitis C virus MPGN: membranoproliferative glomerulonephritis NHL: non-Hodgkin's lymphoma RBCS: red blood cells RPR: reactive plasma reagent SPEP: serum[] ESRD-free survival with proteinase 3 (PR3) versus myeloperoxidase- (MPO-) ANCA positivity stratified into 4 histological classes was investigated.[] The incidence, risk factors, and outcomes of recurrent glomerulonephritis in transplant recipients were determined using adjusted Cox proportional hazard and competing risk[]

  • Vasculitis

    The objective of this study was to investigate the significance of hypoalbuminaemia in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).[] Serum ANCA against myeloperoxidase (MPO) turned positive. Repeated kidney biopsy showed more severe lesion than last time.[] In multivariate analyses, the main determinants of PK-RTX were sex and new diagnosis.[] (CRP), and myeloperoxidase (MPO)-ANCA.[] Abstract We herein describe two cases of refractory antineutrophil cytoplasmic antibody-associated vasculitis (AAV) complicated with diabetes insipidus (DI) possibly related[] KEYWORDS: antiglomerular basement membrane nephritis; myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis; peritubular capillaritis; sensory deafness[] Abstract Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic inflammatory disorder categorized as small-vessel vasculitis.[]

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