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3,540 Possible Causes for (Methotrexate, 2, {2

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  • Sunburn

    Photosensitivity is listed in the drug brochure for methotrexate. However, a review of the literature does not support true photosensitivity associated with methotrexate.[ncbi.nlm.nih.gov] Reapply every 2 hours and after sweating, swimming, or towel-drying (even on cloudy days).[wwwnc.cdc.gov] Solar burn reactivation: this is a rare and idiosyncratic drug reaction, reported with a variety of drugs, including methotrexate.[patient.info]

  • Dementia

    RESULTS: Patients having a decline of 2 points or more in total MMSE score over 2 years had an odds ratio of 3.55 (95% CI, 2.51-5.00) for developing dementia.[ncbi.nlm.nih.gov] There are also studies looking at the use of csDMARDs such as methotrexate to improve outcomes after cardiovascular events.[ncbi.nlm.nih.gov] Tsunoda K 1 , Yamashita T 1 , Shimada H 2 , Nomura E 1 , Takahashi Y 1 , Shang J 1 , Sato K 1 , Takemoto M 1 , Hishikawa N 1 , Ohta Y 1 , Higuchi M 2 , Suhara T 2 , Kokubo[ncbi.nlm.nih.gov]

  • Streptococcal Infection

    This case report illustrates the role of GAS as a trigger for acute onset severe psoriasis in a child whose skin disease initially worsened with a trial of methotrexate.[ncbi.nlm.nih.gov] Med Hypotheses. 2014 Apr;82(4):490-2. doi: 10.1016/j.mehy.2014.02.002. Epub 2014 Feb 12. Author information 1 Meuhedet Health Fund, Tel Aviv, Israel.[ncbi.nlm.nih.gov] Clinical course of the fulminant illness was short (2-4 days). One pathological autopsy case was aged (86-years-old), and hemorrhagic cystitis was observed.[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Her clinical symptoms quickly improved after the cessation of methotrexate and infliximab without the use of anti-viral drugs such as ganciclovir.[ncbi.nlm.nih.gov] Panikkar A 1 , Smith C 2 , Hislop A 3 , Tellam N 2 , Dasari V 2 , Hogquist KA 4 , Wykes M 2 , Moss DJ 2 , Rickinson A 3 , Balfour HH Jr 5 , Khanna R 2 .[ncbi.nlm.nih.gov] Viruses. 2016 Feb 12;8(2). pii: E51. doi: 10.3390/v8020051.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm

    […] topics) Neoplasm of Bone (2 drugs in 2 topics) Legend Off Label This medication may not be approved by the FDA for the treatment of this condition.[drugs.com] Abstract A 77-year-old man with chronic obstructive pulmonary disease was treated with low-dose methotrexate (7.5-15 mg per week).[ncbi.nlm.nih.gov] Second neoplasms were leukemia (10), breast (7), lung (2), kidney (2), central nervous system cancer (2), soft tissue (1), parotid (1), and colon (1).[ncbi.nlm.nih.gov]

  • Adrenal Insufficiency

    Chanson P 1 , Guignat L 2 , Goichot B 3 , Chabre O 4 , Boustani DS 5 , Reynaud R 6 , Simon D 7 , Tabarin A 8 , Gruson D 9 , Reznik Y 10 , Raffin Sanson ML 11 .[ncbi.nlm.nih.gov] Two patients received central nervous system prophylaxis with high-dose methotrexate. Four of the patients survived and one patient died during the follow-up period.[ncbi.nlm.nih.gov] Type Population Prevalence (cases per million) Incidence (cases per million per year) Reference Primary US 40-110 6 Betterle et al. 2011 6 ; NIDDK.2014 2 Primary Norway 144[endocrinefacts.org]

  • Meningitis

    The authors describe 2 cases in which the patients presented with spinal compression resulting in myeloradiculopathy (Case 1) and radiculopathy (Case 2).[otorhinolaryngologybysfakianakisgalexandros.wordpress.com] Treatment with methotrexate, 25 mg weekly, allowed the withdrawal of glucocorticoids and resolution of neurological symptoms.[plu.mx] S 2 , Lazzarotto T 1 .[ncbi.nlm.nih.gov]

  • Appendicitis

    Retrospective review of the history revealed that the patient was on long-term immunosuppressive therapy with methotrexate.[ncbi.nlm.nih.gov] We present 2 pediatric patients with acute myeloid leukemia, who developed appendicitis during the postchemotherapy neutropenic phase, while receiving antifungal prophylaxis[ncbi.nlm.nih.gov] If diagnosed early, treatment is medical including methotrexate to terminate the non-viable preganancy.[jaocr.org]

  • Interleukin-2

    Aminoglycosides, asparaginase, cytotoxic chemotherapy agents, doxorubicin, indomethacin, methotrexate: increased toxicity Antihypertensives: increased hypotensive effect Glucocorticoids[medical-dictionary.thefreedictionary.com] In naive Th cells, Ets-2 mRNA expression, Ets-2 protein levels, and Ets-2 binding to ARRE-2 decrease upon cell activation followed by the concomitant expression of IL-2.[ncbi.nlm.nih.gov] GvHD. 5 A randomized phase II trial using matched related and unrelated donors at the Moffitt Cancer Center (MCC) demonstrated that SIR/tacrolimus (SIR/TAC) was superior to methotrexate[haematologica.org]

  • Idiopathic Pulmonary Fibrosis

    Learn More FAQ: Cyclophosphamide FAQ: Methotrexate FAQ: Mycophenolate FAQ: Prednisone ILD Nutrition Manual GERD in ILD Patients Pulmonary Hypertension and Interstitial Lung[ucsfhealth.org] Objective: To determine the effect of recombinant human pentraxin 2 vs placebo on change from baseline to week 28 in mean forced vital capacity (FVC) percentage of predicted[ncbi.nlm.nih.gov] These include: cyclophosphamide ( Cytoxan ) azathioprine (Imuran, Azasan) methotrexate ( Rheumatrex , Trexall ) penicillamine ( Cuprimine , Depen ) cyclosporine The anti-inflammatory[medicinenet.com]

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