Create issue ticket

2,605 Possible Causes for (NAD(P), ), dehydrogenase, glutamate, glutamate, synthesis,, using

Did you mean: (NAD(P), ), dehydrogenase, glutamate, glutamate, syneresis, using

  • Hyperammonemia

    Phosphorylation of the eukaryotic translation initiation factor 2α (eIF2α) also relates to decreased global protein synthesis rates and mTORC1 signaling.[ncbi.nlm.nih.gov] RESULTS: The number of patients who developed hyperammonemia during VPA-based therapy was 20 (9.9%) using the 200 μg/dL cutoff value and 30 (14.9%) using the 170 μg/dL cutoff[ncbi.nlm.nih.gov] […] second most common cause of hyperinsulinemic hypoglycemia of infancy, and it is caused by activating mutations in GLUD1, the gene that encodes mitochondrial enzyme glutamate dehydrogenase[ncbi.nlm.nih.gov] ( p ) h nicotinamide adenine dinucleotide (phosphate); ass argininosuccinate synthetase; asl argininosuccinate lyase; arg1 arginase 1; ornt1 ornithine transporter; oat ornithine[current-oncology.com] OBJECTIVE: The aim of this research letter was to describe the use of N-carbamoyl-L-glutamate as first-line treatment of hyperammonemia in a 4-month-old female patient with[ncbi.nlm.nih.gov] The genetic diagnosis revealed that the patient carried a heterozygous, de novo missense mutation (N410I, c.1401A T) in the glutamate dehydrogenase 1 gene (GLUD1).[ncbi.nlm.nih.gov] INTRODUCTION: Congenital hyperinsulinism and hyperammonemia (CHH) is caused by gain of function of glutamate dehydrogenase (GDH).[ncbi.nlm.nih.gov]

    Missing: )
  • Pyruvate Carboxylase Deficiency

    […] of cholesterol and ketone bodies), and fatty acid synthesis.[ncbi.nlm.nih.gov] This is a compassionate use study to allow patients already taking triheptanoin (C7) through previous studies to continue to receive the supplement.[clinicaltrials.gov] However, pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase activities in liver tissues were within normal limits.[ncbi.nlm.nih.gov] IPERLATTACIDEMIE con AUMENTATO RAPPORTO L/P • deficit di Piruvico Carbossilasi (PC) - deficit di Biotinidasi Glucosio • deficit del ciclo di Krebs NAD β OHbutirrico • deficit[slideshare.net] Glutamine content was greatly reduced in all brain regions, while glutamic acid and proline contents were elevated.[ncbi.nlm.nih.gov] […] complex deficiency Phosphoenolpyruvate carboxykinase deficiency 2-Ketoglutarate dehydrogenase deficiency Dihydrolipoamide dehydrogenase deficiency Fumarase deficiency Lab[emedicine.medscape.com] US: multicystic changes bilaterally US: minimal ventricular dilatation US: bilateral cysts MRI: severe cortical atrophy MRI: intraventricular retrocerebral subdural hemorrhagia[ncbi.nlm.nih.gov]

    Missing: )
  • Stiff-Person Syndrome

    Immunoblotting revealed stronger staining in the CSF, suggestive of intrathecal IgG synthesis, in 7/10 patients upon visual inspection, and in 8/10 patients upon densitometric[ncbi.nlm.nih.gov] The patient's walking, stiffness, and anxiety were assessed during and post-therapy using questionnaires.[ncbi.nlm.nih.gov] […] development require the plasmapheresis, mycophenolat mofetil, and rituximab therapy that results in a significant decrease of GADAb, impaired glucose tolerance (IGT), lactate dehydrogenase[ncbi.nlm.nih.gov] RESULTS: Intra-cerebellar administration of GAD65-Ab from a SPS patient (Ab SPS) impaired the NMDA-mediated turnover of glutamate, but had no effect on NMDA-mediated turnover[ncbi.nlm.nih.gov] Despite evidence that anti-GAD and related autoantibodies impair GABA synthesis, the exact pathogenic mechanism of SPS is not fully elucidated.[ncbi.nlm.nih.gov] Dinkel K, Rickert M, Möller G et al (2002) Stiff-man syndrome: identification of 17 beta-hydroxysteroid dehydrogenase type 4 as a novel 80-kDa antineuronal antigen.[link.springer.com] IMPORTANCE: High titers of autoantibodies to glutamic acid decarboxylase (GAD) are well documented in association with stiff person syndrome (SPS).[ncbi.nlm.nih.gov]

    Missing: (NAD(P) )
  • Ketamine

    This article presents a synthesis of the data on ketamine for refractory cancer pain in adults and children.[ncbi.nlm.nih.gov] To prevent ketamine from being improperly used and evolving into an epidemic, a thorough survey on the prevalence and characteristics of illicit ketamine use is imperative[ncbi.nlm.nih.gov] CASE SUMMARY: A 2-year-old girl with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and stable hypertrophic cardiomyopathy was admitted to the pediatric intensive care[ncbi.nlm.nih.gov] This review focuses on the use of glutamate receptor modulators for depression in bipolar disorder. 1.[ncbi.nlm.nih.gov] The synthesis of 12 hydroxynorketamines and their binding affinity to the NMDA receptor is presented here.[ncbi.nlm.nih.gov] In addition, no significant effect was observed on lactate dehydrogenase (LDH) release (indicating necrotic cell death) in ketamine-treated (10μM) rat cultures ( Wang et al[doi.org] Design This article presents a synthesis of the data on ketamine for refractory cancer pain in adults and children.[doi.org]

    Missing: (NAD(P) )
  • Aldehyde

    Grunfeld Experientia 1973 29 (10), 1193-1195 Synthesis of ?Pear Ester?.[doi.org] Using a multiple reaction-monitoring mass spectrometry analysis, we found that multiple ALDH isozymes were generally abundant in NSCLC cells compared with their levels in[ncbi.nlm.nih.gov] These enzymes include alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which play a significant role in the metabolism of many biological substances and exist[ncbi.nlm.nih.gov] Can use ferredoxin or methylviologen but not NAD(P) as electron acceptor. Please wait a moment until the data is sorted.[brenda-enzymes.org] Head and neck CSC (CD44 hi /ALDH hi ) exhibited higher glutaminase, glutamate, and sphere levels than CD44 lo /ALDH lo cells.[ncbi.nlm.nih.gov] IHC was performed using an immunoperoxidase method with a primary polyclonal rabbit anti-ALDH1A1 antibody.[ncbi.nlm.nih.gov] We review the known uses of different RAs in the treatment of cancers.[ncbi.nlm.nih.gov]

    Missing: )
  • Connective Tissue Disease

    Ehlers–Danlos syndrome – defect in the synthesis of collagen (Type I or III) causes progressive deterioration of collagens, with different EDS types affecting different sites[en.wikipedia.org] What tests to doctors use to diagnose connective tissue diseases?[medicinenet.com] […] deficiency with mild methylmalonic acidemia Methylmalonic semialdehyde dehydrogenase (see also Branched-chain amino acid metabolism, above) ALDH6A1 (14q24.1) Biochemical[merck.com] Long term use of immunesuppressants and corticosteroids has been associated with increased risk of infections.[symptoma.com] Latent lupus and incomplete lupus are alternative terms that have been used to describe this condition. Psoriatic arthritis is also a collagen vascular disease.[en.wikipedia.org] Collagen vascular disease is a somewhat antiquated term used to describe diseases of the connective tissues that typically include diseases that can be (but are not necessarily[medicinenet.com] : Benign Treatment: None needed Pyridoxine dependency with seizures (266100) Not determined Specific gene not determined (5q31.2-q31.3) Biochemical profile: Elevated CSF glutamate[merck.com]

    Missing: (NAD(P) )
  • Glucocorticoid

    Similarly, PGI2 synthesis from arachidonic acid fell 86% with DEX; all of the above effects are consistent with COX-1 downregulation.[ncbi.nlm.nih.gov] In this case, the main compounds used are beclometasone, budesonide, fluticasone, mometasone and ciclesonide. In rhinitis, sprays are used.[en.wikipedia.org] […] databases PTM / Processing i Molecule processing Feature key Position(s) Description Actions Graphical view Length Chain i PRO_0000054619 1 – 292 Corticosteroid 11-beta-dehydrogenase[uniprot.org] 1019 [PubMed:22201787] [WorldCat.org] 12.0 12.1 Maurizio Popoli, Zhen Yan, Bruce S McEwen, Gerard Sanacora The stressed synapse: the impact of stress and glucocorticoids on glutamate[bsd.neuroinf.jp] Result Figure 5 (March 2009) Expansion, grouping, numbering of cholesterol and coloring by Häggström The abbreviation HSD stands for "hydroxysteroid dehydrogenase".[doi.org] Effect of acute stress on hippocampal glutamate levels and spectrin proteolysis in young and aged rats . J. Neurochem. 65 , 268–274 (1995). 111. Raskind, M.[doi.org] Effect of DEX on PGI 2 synthesis in fetal PAECs.[doi.org]

    Missing: )
  • Formiminotransferase Deficiency

    […] precursor of S-adenosylmethionine, a potent inhibitor of 5-methyltetrahydrofolate synthesis; methionine serves as a source of formate for purine synthesis; and rates of purine[jci.org] Abstract During the past six years an increasing number of liver-cell adenomas in women were diagnosed, and we undertook a study of possible etiologic faciors, including use[nejm.org] 3 Hydroxy Acyl CoA Dehydrogenase Deficiency Trifunctional Protein Deficiency Very Long Chain AcylCoA Dehydrogenase Deficiency Short Chain AcylCoA Dehydrogenase Deficiency[neolab.gr] […] the bifunctional enzyme glutamate formiminotransferase-cyclodeaminase (FTCD).[ncbi.nlm.nih.gov] Finding useful health information on the Internet can be difficult, but we’re here to help. This page gathers quality information from trusted sources.[diseaseinfosearch.org] […] formiminotransferase deficiency See more descriptions. - Deficiency of glutamate formiminotransferase - Deficiency of glutamate formyltransferase - Glutamate formiminotransferase[snomedbrowser.com] الصفحة 193 - Till, JE, The effect of differing demands for blood cell production on DNA synthesis by hemopoietic colony-forming cells of mice. ‏[books.google.com]

    Missing: (NAD(P) )
  • Disorder of Pyrimidine Metabolism

    Synthesis of AMP and GMP from IMP. Following the synthesis of IMP, this nucleotide can serve as a precursor for both AMP and GMP synthesis.[themedicalbiochemistrypage.org] A 'billable code' is detailed enough to be used to specify a medical diagnosis.[icd.codes] E79.8 MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT 900000000000508004 ACCEPTABILITYID 900000000000548007 6011000124106 MAPGROUP 1 6011000124106 MAPADVICE IF DIHYDROURACIL DEHYDROGENASE[purl.bioontology.org] : Key metabolic branch points Pyruvate Oxaloacetate (Anaplerosis) ------ Glucose-6-P (Gluconeogenesis) Pyruvate Lactate (Lactate Dehydrogenase, regeneration of NAD ) Pyruvate[kumc.edu] […] deficiency (274270) Inborn error form Pharmacogenetic form Dihydropyrimidine dehydrogenase DPYD (1p22)* Biochemical profile: Elevated urinary uracil, thymine, and 5-hydroxymethyluracil[merckmanuals.com] When an Excludes2 note appears under a code it is acceptable to use both the code and the excluded code together.[icd10coded.com] Abstract Heterozygous dihydropyrimidine dehydrogenase (DPD) deficiency is defined as a pharmacogenetic syndrome.[degruyter.com]

    Missing: )
  • Sarcosinemia

    Disorder of creatine synthesis Disorder of isoleucine metabolism Disorder of lysine and hydroxylysine metabolism Disorder of phenylalanine metabolism Disorder of proline[icd9data.com] The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.[orpha.net] Sarcosine is a key intermediate in 1-carbon metabolism and under normal circumstances is converted to glycine by the enzyme sarcosine dehydrogenase.[ncbi.nlm.nih.gov] BioCyc Guanidinoacetate N-methyltransferase 743 ChemSpider 5-AMINO-LEVULINATE BioCyc Aminomethyltransferase, mitochondrial 740 ChemSpider 3-P-SERINE BioCyc SMILES [H][[email protected]@[smpdb.ca] […] α-ketoglutarate Histidine Carnosinemia · Histidinemia · Urocanic aciduria Proline Hyperprolinemia · Prolidase deficiency Glutamate / glutamine SSADHD G propionyl-CoA succinyl-CoA[wiki30.com] Copyright 1984 by the American Academy of Pediatrics Log in using your username and password Log in through your institution You may be able to gain access using your login[pediatrics.aappublications.org] Sarcosine Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation.[howlingpixel.com]

    Missing: )