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3,592 Possible Causes for (S, 1, REX1,, RNA, exonuclease, homolog

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  • Influenza

    IL-1 receptor (IL-1R1).[doi.org] Most RNA viruses that lack a DNA phase replicate in the cytoplasm.[ncbi.nlm.nih.gov] Amplicons were prepared for sequencing by incubating them at 37  C for 60 min with 0.5 U of shrimp alkaline phosphatase (Amersham) and 1 U of exonuclease I (Amersham) to inactivate[dx.doi.org] , Ryuto M , Sakaguchi S , Sakayori S , Sasaki Y , Sato S , Sato T , Sato Y , Sato Y , Segawa Y , Shibasaki A , Shimamoto E , Shimomura H , Sugiura T , Suzuki S , Suzuki T[ncbi.nlm.nih.gov] Heterologous mean HI titers were normalized to mean homologous HI titers (mean heterologous titers/mean homologous titers).[doi.org] Lytic RNA viruses thus mutate at a rate close to the maximum value compatible with viability.[doi.org]

    Missing: REX1
  • Werner Syndrome

    Hypoxia-inducible factor-1 (HIF-1) is a decisive element for the transcriptional regulation of genes essential for adaptation to low oxygen conditions.[ncbi.nlm.nih.gov] Genet. 62 , 25–30 (1982). 32 Samantray, S. K., Samantray, S., Johnson, S. C. & Bhaktaviziam, A. Aust. N.Z. J. Med. 7 , 309–311 (1977). 33 Sparkes, R. S. et al.[doi.org] It has been suggested that, in addition to RNA pol II, RNA pol I activity is affected in WS cells ( 33 ).[doi.org] Both Pol δ and WRN encode 3' 5' DNA exonuclease activities.[ncbi.nlm.nih.gov] Such homology does not necessarily mean that WRN encodes an active helicase.[ncbi.nlm.nih.gov] Abstract WRN is a RecQ helicase with an associated exonuclease activity important in DNA metabolism, including DNA replication, repair and recombination.[ncbi.nlm.nih.gov]

    Missing: REX1
  • Hepatitis C Virus

    In addition, shHO-1 inhibited HCV replication. CONCLUSION: In conclusion, hypericin inhibits HCV replication via down-regulation of HO-1 expression and deacetylation.[ncbi.nlm.nih.gov] Kaito, M, Watanabe, S, Tsukiyama-Kohara, K, Yamaguchi, K, Kobayashi, Y, Konishi, M, Yokoi, M, Ishida, S, Suzuki, S, Kohara, M 1994 Hepatitis C virus particle detected by immunoelectron[doi.org] , Small Interfering/metabolism RNA, Viral/metabolism Virus Replication/genetics Substances MIRN122 microRNA, human MicroRNAs RNA, Small Interfering RNA, Viral Exoribonucleases[ncbi.nlm.nih.gov] To address this challenge, we searched for homologous viruses in small mammals, including wild rodents.[ncbi.nlm.nih.gov] Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus (HCV) from two crystal forms have been determined.[ncbi.nlm.nih.gov] Comparative phylogenetic analysis of the canine hepacivirus (CHV) confirmed it to be the most genetically similar animal virus homolog of HCV.[ncbi.nlm.nih.gov]

    Missing: REX1
  • Shigella Dysenteriae

    This report describes a 22 year old woman who acquired Shigella dysenteriae type 1 whilst travelling in India.[ncbi.nlm.nih.gov] S. Mohran, S. H. El-Etr, M. O. Wasfy, and L. F. Peruski, Jr. 1996 .[aem.asm.org] , Bacterial/chemistry RNA, Bacterial/genetics RNA, Bacterial/metabolism RNA, Untranslated/chemistry RNA, Untranslated/genetics* RNA, Untranslated/metabolism Shigella dysenteriae[ncbi.nlm.nih.gov] Then the A subunit can enter the cell, where it will be cleaved to an active exonuclease (A1).[vetbact.org] Analysis of the shuA DNA sequence indicates that this gene encodes a protein with homology to TonB-dependent receptors of gram-negative bacteria.[ncbi.nlm.nih.gov] Abstract The Shiga toxin (Stx) region of Shigella dysenteriae 1 lies on a defective prophage homologous to lambdoid bacteriophages in Stx-producing Escherichia coli.[ncbi.nlm.nih.gov]

    Missing: REX1
  • LIG4 Syndrome

    […] and 2.39 at 1 and 24 hours, respectively) and NK cells (HC1, 49.80 and 3.26 at 1 and 24 hours, respectively; HC2, 58.38 and 2.57 at 1 and 24 hours, respectively).[bloodadvances.org] .}, author {S. C. Unal and Karen Cerosaletti and Duygu Uçkan-Çetinkaya and M.[semanticscholar.org] […] before and after exposure to low doses of ionizing radiation Mutation research683:91-7 2009 PubMed ID: 19896956 Muylaert I, Elias P , Knockdown of DNA ligase IV/XRCC4 by RNA[coriell.org] Sarcoma, Avian DNA ligase and exonuclease activities in virions of rous sarcoma virus.[brenda-enzymes.org] LIG4 syndrome is conferred by hypomorphic mutations in DNA ligase IV, an essential component of DNA non-homologous end-joining (NHEJ), and is associated with pancytopaenia[ncbi.nlm.nih.gov] Structure-guided mutational analysis of T4 RNA ligase 1. RNA 12 , 2126–2134 (2006). 39. Yin, S., Ho, C. K. & Shuman, S. Structure-function analysis of T4 RNA ligase 2.[nature.com]

    Missing: REX1
  • Infectious Mononucleosis

    Author information 1 Department of Pediatrics, Fukuiken Saiseikai Hospital, Wadanaka-machi, 7-1 Funahashi, Fukui, Fukui 918-8503, Japan. [email protected] Abstract We report[ncbi.nlm.nih.gov] Alfred S.[nytimes.com] In-situ hybridization for EBV-encoded RNA with immunostaining against CD20 was used for evaluation of EBV infection.[ncbi.nlm.nih.gov] The Epstein-Barr virus alkaline exonuclease BGLF5 serves pleiotropic functions in virus replication. J. Virol. 83 : 4952 -4962. Fingeroth, J. D., J. J. Weis, T. F.[dx.doi.org] On in situ hybridization, numerous Epstein-Barr virus (EBV)-encoded small RNA (EBER)-positive cells were demonstrated in the germinal center, as well as in interfollicular[ncbi.nlm.nih.gov] Quantitative HIV RNA and p24 antigen detection are more sensitive for diagnosing acute HIV infection because HIV RNA and p24 antigen are present in blood before HIV antibodies[merck.com]

    Missing: REX1
  • Poliovirus

    Enterovirus C Genbank AJ132961 Human poliovirus 1, complete genome.[genome.jp] VPg is linked to the genomic RNA through the 5′-terminal uridylic acid of the RNA. We show that VPg can be uridylylated by the poliovirus RNA polymerase 3D pol .[nature.com] Production of single-stranded DNA templates by exonuclease digestion following the polymerase chain reaction.[ncbi.nlm.nih.gov] S., N. H. Olson, and S. D. Fuller. 1999.[ncbi.nlm.nih.gov] Furthermore, this isolate had higher homology to the isolates from North Vietnam than those from Pakistan or Finland, suggesting that the Shiga strain was imported from Asian[ncbi.nlm.nih.gov] These high mutation rates are attributable to the absence of 3′ 5′ exonuclease proofreading mechanisms for the viral RNA polymerases ( 19 ), although other mechanisms may[doi.org]

    Missing: REX1
  • Acute Gastroenteritis

    J Med Virol. 2017 Jan;89(1):17-23. doi: 10.1002/jmv.24593. Epub 2016 Jul 11.[ncbi.nlm.nih.gov] Previously reported cases of S. algae have mainly been associated with direct contact with seawater.[ncbi.nlm.nih.gov] Extracted viral RNA was separated by polyacrylamide gel electrophoresis (PAGE) and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined.[ncbi.nlm.nih.gov] Sequencing of a portion of the capsid gene and the ORF1/ORF2 overlap was used to assess DNA sequence homology, phylogeny, and recombination using pairwise alignments, MEGA[ncbi.nlm.nih.gov] Huang XY 1, 2 , Su J 1 , Lu QC 3 , Li SZ 3 , Zhao JY 1, 2 , Li ML 1 , Li Y 1, 2 , Shen XJ 1 , Zhang BF 1, 2 , Wang HF 1 , Mu YJ 1, 2 , Wu SY 4 , Du YH 1, 2 , Liu LC 5, 6 ,[ncbi.nlm.nih.gov] Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved.[ncbi.nlm.nih.gov]

    Missing: REX1 exonuclease
  • Rotavirus

    There wasn’t a meaningful change in type 1 diabetes cases among older kids, however.[reuters.com] Filipski, S. Kumar, Mol. Biol. Evol. 30 , 2725–2729 (2013) CrossRef PubMed PubMedCentral Google Scholar 13. C.F. Arias, S. Lopez, J.R. Bell, J.H. Strauss, J.[doi.org] […] may have affinity for RNA.[doi.org] Subsequently, the 7-methylguanosine cap was found to protect mRNA from degradation by exonuclease activity [ 40 ].[doi.org] Even NS53 from viruses isolated from the same species possessed relatively poor homology, e.g., DS1 versus Wa was 68%.[ncbi.nlm.nih.gov] […] responses produced after both natural infection and vaccination, and the fact that animal models do not fully mimic the human immunologic responses, even when inoculated with homologous[dx.doi.org]

    Missing: REX1
  • Lassa Virus

    PtdSer-binding pocket of TIM-1.[ncbi.nlm.nih.gov] RNA copies/ml serum, which corresponds to 4 to 30 S RNA copies/assay.[ncbi.nlm.nih.gov] Here, we present crystal structures of the RNA-binding domain of Lassa virus NP in complex with ssRNA.[ncbi.nlm.nih.gov] Although the fold of the NP enzyme is conserved and the active site completely conserved with other exonucleases in its DEDDh family, NP is atypical among exonucleases in[ncbi.nlm.nih.gov] It was found that while the GPC extravirion domains were readily exchangeable, homologous stable signal peptide (SSP) and G2 transmembrane and cytoplasmic tail domains were[ncbi.nlm.nih.gov] With the Nigeria strain of Lassa virus the levels of homology were 100% for two of these epitopes and 85% for three of them, whereas homology with the respective Mopeia epitopes[ncbi.nlm.nih.gov]

    Missing: REX1