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10,127 Possible Causes for (activated, B cell, factor 1), human, musculin, protein

Did you mean: (activated, B cell, factor ix, human, musculin, proteus

  • Influenza

    Incidence rates are shown for high‐risk (at least 1 risk factor for influenza‐related serious morbidity) and low‐risk (no identifiable risk factors for influenza morbidity[doi.org] Seasonal influenza activity in the Southern Hemisphere was low overall, with influenza A(H1N1)pdm09 predominating in many regions.[ncbi.nlm.nih.gov] A consensus H1 protein (CH1) was generated and was further modified with published conserved T-cell and B-cell epitopes.[ncbi.nlm.nih.gov] The rapid evolution of influenza A and B viruses contributes to annual influenza epidemics in humans.[ncbi.nlm.nih.gov] Like hemagglutinin and neuraminidase, the M2 protein is an integral membrane protein of the influenza A virus 4 , 5 .[dx.doi.org] Nationally, ILI activity began increasing in November, reaching an extended period of high activity during January-February, and remaining elevated through March.[ncbi.nlm.nih.gov]

    Missing: musculin
  • Primary Effusion Lymphoma

    However, the underlying mechanisms of c-MET activation within PEL cells remain largely unknown.[ncbi.nlm.nih.gov] It is a tumor of B-cell lineage; however, it shows a "null" phenotype, rarely expressing pan-B cell surface antigens.[ncbi.nlm.nih.gov] The mRNA and protein levels of hTERT were examined by real time-PCR and Western blotting, respectively.[ncbi.nlm.nih.gov] 8) in conjunction with human immunodeficiency virus (HIV) infection.[ncbi.nlm.nih.gov] Fucoidan also suppressed nuclear factor-κB, activator protein-1 (AP-1), and T-lymphokine-activated killer cell-originated protein kinase (TOPK) signaling pathways through[ncbi.nlm.nih.gov] Abstract Primary effusion lymphoma is a rare subclass of non-Hodgkin lymphoma associated with human herpesvirus 8 infection and principally seen in human immunodeficiency[ncbi.nlm.nih.gov]

    Missing: musculin
  • LIG4 Syndrome

    Melanoma Apurinic/apyrimidinic endonuclease /redox effector factor-1(APE/Ref-1) a unique target for the prevention and treatment of human melanoma.[brenda-enzymes.org] Given the expected severe effect of Dnl4 catalytic mutation on ligase activity and c-NHEJ, it was striking that these same mutants supported residual NHEJ activity in the[journals.plos.org] We report here on a case of LIG4 syndrome complicated with distinct EBV-associated B-cell lymphoma.[ncbi.nlm.nih.gov] PAGES GENES INVOLVED Human Gene Zebrafish Ortholog OMIM Term OMIM Phenotype ID LIG4 lig4 LIG4 syndrome 606593 ZEBRAFISH MODELS No data available PHENOTYPE No data available[zfin.org] Tandem BRCT domains of LigIV mediate a unique mode of protein-protein interaction.[mcb.asm.org] […] associated with B cell lymphopenia ( 34 ).[pnas.org]

    Missing: musculin
  • Herpes Simplex Virus 1 Infection

    The active form of the actin-depolymerizing factor cofilin 1 was found to increase at an early stage of infection and then to continuously decrease in a manner that corresponded[ncbi.nlm.nih.gov] Additionally, caspase 7 was found to be activated during HSV-1-dependent apoptosis.[ncbi.nlm.nih.gov] […] and B-cell defects contributed to the impaired production of antibody.[ncbi.nlm.nih.gov] We examined whether human neuronal cells (primary human neurons, NT2-N and CHP-212 cells) express TLRs and mount type I IFN-mediated innate immunity against herpes simplex[ncbi.nlm.nih.gov] Sections from the cultured TG fragments were stained with antisera against non-structural proteins such as the immediate early (IE) protein ICP27 and the early (E) proteins[ncbi.nlm.nih.gov] HSV-1 infection of HCECs resulted in a two-phase activation of nuclear factor-kappaB (NF-kappaB), JNK and p38, with the first peak at 1-4 hr and a second peak at 8 hr.[ncbi.nlm.nih.gov]

    Missing: musculin
  • Epstein Barr Virus

    PLoS Pathog. 2018 Jan 22;14(1):e1006868. doi: 10.1371/journal.ppat.1006868. eCollection 2018 Jan.[ncbi.nlm.nih.gov] In addition to the previously described endonuclease and exonuclease activities on single-stranded DNA and dsDNA substrates, we observed an RNase activity for Epstein-Barr[ncbi.nlm.nih.gov] AIMS: A new subtype of granzyme B (GrB)-producing regulatory B cells (B regs ) has been described recently; these peculiar cytotoxic B cells are increased significantly in[ncbi.nlm.nih.gov] […] in the human interactome network.[doi.org] Considering that transcription factor specificity protein 1 (Sp1) can maintain EBNA1 Qp active.[ncbi.nlm.nih.gov] The final diagnosis of EBV-positive DLBCL was confirmed based on the expression of B-cell-specific transcription factors (Oct-2 and BOB.1), PCR-based identification of monoclonal[ncbi.nlm.nih.gov]

    Missing: musculin
  • Interleukin-2

    The ‘adaptive’ arm of IL-2 dependent activation IL-2 plays a dual role in T cell activation by stimulating the proliferation and differentiation of ‘conventional’ T cells[invivogen.com] The results showed that DSP30/IL2 was an effective mitogen in mature B-cell disorders, revealing abnormal cytogenetic results in a range of B-cell malignancies.[ncbi.nlm.nih.gov] In this study, we show that their lower responsiveness to IL-2 is due to the selective expression of Musculin (MSC), a member of the basic helix-loop-helix transcription factors[ncbi.nlm.nih.gov] Search results for IL2 Gene & protein summaries for IL2 Gene summary for IL2 Gene & protein summary for IL2 ORGANISMS human Homo sapiens human Homo sapiens house mouse Mus[ebi.ac.uk] […] including NF-kB , nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 ( NF-AT1 ), Early growth response 1 ( EGR1 ), E74-like factor 1 ( ELF1 ), Elk-1 ,[lsresearch.thomsonreuters.com] Technical specifications of human IL2 kit Sample size 16 µL Final assay volume 20 µL Kit components Lyophilized standard, frozen detection antibodies, buffers &protocol.[cisbio.com]

  • Insulin-Like Growth Factor I

    KEYWORDS: Aging; Insulin-like growth factor 1; Motor system; Muscle strength; Testosterone[ncbi.nlm.nih.gov] At mean age 36, physical activity, fitness and IGF-I were measured.[ncbi.nlm.nih.gov] We report here a 26-year-old female with diffuse large B-cell lymphoma who died of severe pulmonary fibrosis 81 days after the administration of high-dose BCNU (600 mg/m2)[ncbi.nlm.nih.gov] Growth hormone (GH) plays an essential role in controlling somatic growth and in regulating multiple physiological processes in humans and other species.[ncbi.nlm.nih.gov] The encoded protein is processed from a precursor, bound by a specific receptor, and secreted.[genecards.org] LP) cells in NLPHL, both occurring within a microenvironment of, for example, reactive T and B cells, macrophages and granulocytes that are assumed to support the proliferation[ncbi.nlm.nih.gov]

    Missing: musculin
  • Human Herpesvirus 8

    Here, we report that human herpesvirus 8 (HHV-8) gene product viral interferon regulatory factor 1 (vIRF-1) is targeted to mDRM during virus replication and negatively regulates[ncbi.nlm.nih.gov] Diminished STAT activation was also detected in JSC-1 and BC-3 cells.[ncbi.nlm.nih.gov] B-cell lymphoma occurring in HHV-8-related MCD.[ncbi.nlm.nih.gov] In 1994, Chang and Moore reported on the latest of the gammaherpesviruses to infect humans, human herpesvirus 8 (HHV-8).[ncbi.nlm.nih.gov] […] response signaling in addition to enhancing viral protein folding.[ncbi.nlm.nih.gov] Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRF-1 to -4) that likely function to suppress innate immune and cellular stress responses through[ncbi.nlm.nih.gov]

    Missing: musculin
  • Infectious Mononucleosis

    Evidence also exists to suggest Epstein-Barr virus infection as an adult is a risk factor for the development of multiple sclerosis. [1, 2] Hematologic complications can include[emedicine.medscape.com] The mitogen responses were decreased and natural killer (NK) cell activity was low.[dx.doi.org] […] with a significant reduction in memory B cells and no evidence of circulating antibody-secreting cells.[ncbi.nlm.nih.gov] Author information 1 Michigan State University College of Human Medicine, East Lansing, MI, United States. 2 Section of Emergency Medicine, Department of Internal Medicine[ncbi.nlm.nih.gov] The defective gene is the signaling lymphocyte activation molecule (SLAM)–associated protein ( SAP ) and is found on the X chromosome.[emedicine.medscape.com] Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a member of the herpes virus family. It is one of the most common human viruses.[cdc.gov]

    Missing: musculin
  • T-cell Acute Lymphoblastic Leukemia

    Moreover, Rack1 overexpression reduced the level of cytochrome c and active caspase 3 as well as FEM1b and apoptotic protease activating factor-1 (Apaf-1), and inhibited induction[ncbi.nlm.nih.gov] We also identified evidence of NOTCH3 activation in 12 of 24 patient-derived orthotopic xenograft models, 2 of which exhibit activation of NOTCH3 without activation of NOTCH1[ncbi.nlm.nih.gov] Abstract Different therapeutic methods have been developed for the B-cell and T-cell subtypes of acute lymphoblastic leukemia (ALL).[ncbi.nlm.nih.gov] Plumbagin is a natural, plant derived compound, which exerts an anti-proliferative activity against many types of human cancer.[ncbi.nlm.nih.gov] * Neoplasm Proteins/biosynthesis Neoplasm Proteins/genetics Nuclear Proteins/antagonists & inhibitors Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy* Protein[ncbi.nlm.nih.gov] , dynamin-related protein 1 (Drp1), at residue S616.[ncbi.nlm.nih.gov]

    Missing: musculin