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10,839 Possible Causes for (bromodomain, 1), BRD1, containing, human, protein

Did you mean: (bromodomain, 1), BRD1, containing, human, proteus

  • Influenza

    IL-1 receptor (IL-1R1).[dx.doi.org] The rapid evolution of influenza A and B viruses contributes to annual influenza epidemics in humans.[ncbi.nlm.nih.gov] Containment is unlikely if R 0 exceeds 1.8 for the new pandemic strain.[doi.org] Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface. Cell 40 , 627–633 (1985). 5. Zebedee, S.L. & Lamb, R.A.[dx.doi.org] Despite vast clinical experience in human beings, there continues to be much debate about how influenza is transmitted.[ncbi.nlm.nih.gov] Other interventions aimed at reducing population contact rates are also examined as reinforcements to an antiviral-based containment policy.[ncbi.nlm.nih.gov]

    Missing: (bromodomain BRD1
  • LIG4 Syndrome

    The documents contained in this web site are presented for information purposes only.[orpha.net] Tandem BRCT domains of LigIV mediate a unique mode of protein-protein interaction.[mcb.asm.org] […] and 2.39 at 1 and 24 hours, respectively) and NK cells (HC1, 49.80 and 3.26 at 1 and 24 hours, respectively; HC2, 58.38 and 2.57 at 1 and 24 hours, respectively).[bloodadvances.org] Our displays determined bromodomain and extra-terminal (Wager) bromodomain inhibitors and beta-2 adrenergic receptor agonists as classes of substances that suppress appearance[perlierusa.com] PAGES GENES INVOLVED Human Gene Zebrafish Ortholog OMIM Term OMIM Phenotype ID LIG4 lig4 LIG4 syndrome 606593 ZEBRAFISH MODELS No data available PHENOTYPE No data available[zfin.org] This article contains supporting information online at www.pnas.org/cgi/content/full/0914865107/DCSupplemental .[pnas.org]

    Missing: BRD1
  • Human Herpesvirus 8

    CONCLUSIONS: HAART regimens that contain PIs appear to decrease HHV-8 shedding compared to NNRTIs.[ncbi.nlm.nih.gov] […] response signaling in addition to enhancing viral protein folding.[ncbi.nlm.nih.gov] Among HIV-1 positive samples, HHV-8 seropositivity rate was 61% based on combined reactivity using both ELISA and IFA techniques.[ncbi.nlm.nih.gov] Bromodomain factor 1 (Bdf1) protein interacts with histones.[doi.org] In 1994, Chang and Moore reported on the latest of the gammaherpesviruses to infect humans, human herpesvirus 8 (HHV-8).[ncbi.nlm.nih.gov] This report describes a 77-year-old male patient with pleural effusion and ascites, containing lymphoma cells expressing a B-cell phenotype, but without markers of HHV8 in[ncbi.nlm.nih.gov]

    Missing: BRD1
  • Primary Effusion Lymphoma

    Abstract To date, there are only 15 case reports of lymphoma in patients with neurofibromatosis type 1 (NF1), a common autosomal dominant tumor predisposition syndrome.[ncbi.nlm.nih.gov] JQ1, a bromodomain and extra terminal (BET) protein inhibitor, in combination with PEP005, not only robustly induced KSHV lytic replication, but also inhibited IL6 production[ncbi.nlm.nih.gov] 8) in conjunction with human immunodeficiency virus (HIV) infection.[ncbi.nlm.nih.gov] It is suggested that effusion drainage followed by chemotherapy containing rituximab is a potential treatment strategy for patients with HHV-8/KSHV-negative and CD20-positive[ncbi.nlm.nih.gov] The mRNA and protein levels of hTERT were examined by real time-PCR and Western blotting, respectively.[ncbi.nlm.nih.gov] Abstract Silencing of the B lymphocyte-induced maturation protein 1 (Blimp-1), a pivotal transcriptional regulator during terminal differentiation of B cells into plasma cells[ncbi.nlm.nih.gov]

    Missing: BRD1
  • Saccharomyces Cerevisiae

    Author information 1 Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. [email protected] 2[ncbi.nlm.nih.gov] Helicase superfamily 1/2, ATP-binding domain / Glutamine-Leucine-Glutamine, QLQ / SNF2-related, N-terminal domain / Histone H2B / Bromodomain / Helicase, C-terminal / Histone[pdbj.org] Conversely, the tri-snRNP protein Spp381 is one of only five S. cerevisiae splicing factors without a known human ortholog.[ncbi.nlm.nih.gov] To overcome this hurdle we have developed a new approach, the essence of which is a coexpression system containing a human, or another mammalian UDP-glucuronosyltransferases[ncbi.nlm.nih.gov] […] machinery, especially the protein secretory pathway.[ncbi.nlm.nih.gov] The yeast Saccharomyces cerevisiae has the ASP1 gene responsible for encoding L-asparaginase 1 (ScASNase1), an enzyme predicted as type II, like bacterial therapeutic isoforms[ncbi.nlm.nih.gov]

    Missing: BRD1
  • Amprenavir

    Abstract In an attempt to determine whether mutations in Gag in human immunodeficiency virus type 1 (HIV-1) variants selected with a protease inhibitor (PI) affect the development[ncbi.nlm.nih.gov] Recent advances in the application of cutting-edge in silico tools in the research of drugs targeting bromodomain modules Vassilios Myrianthopoulos , Emmanuel Mikros Biochemical[dx.doi.org] Abstract A sensitive bio-analytical assay for amprenavir, a human immunodeficiency virus protease inhibitor, based on reversed-phase liquid chromatography and fluorescence[ncbi.nlm.nih.gov] Of the multiple factors examined, only the C(min)/IC(50) ratio was a significant predictor of antiviral response in the first 8 weeks on amprenavir-containing combination[ncbi.nlm.nih.gov] Abstract This secondary analysis explored changes in protein-unbound concentrations of lopinavir and amprenavir when coadministered in HIV-infected subjects.[ncbi.nlm.nih.gov] […] inhibitors (PIs) (amprenavir (APV), lopinavir (LPV), ritonavir (RTV) and saquinavir (SQV)) and a non-nucleoside reverse transcriptase inhibitor (NNRTI) (efavirenz, EFV) in human[ncbi.nlm.nih.gov]

    Missing: BRD1
  • Herpes Simplex Virus 1

    The Us11 protein of herpes simplex virus 1 (HSV-1) is an accessory factor with multiple functions.[ncbi.nlm.nih.gov] Oral mucosa is one of the main target tissues of the human pathogen herpes simplex virus 1 (HSV-1).[ncbi.nlm.nih.gov] Using transmission electron microscopy, we detected for the first time microvesicles containing HSV-1 virions.[ncbi.nlm.nih.gov] During viral infection, accumulation of viral proteins can cause stress in the endoplasmic reticulum (ER) and trigger the unfolded protein response (UPR) to restore ER homeostasis[ncbi.nlm.nih.gov] Here, we examined whether Cbl mediates the removal of the herpes simplex virus 1 (HSV-1) entry receptor Nectin-1 from the surface of infected cells.[ncbi.nlm.nih.gov] Nonetheless, few studies have looked specifically at entry into these relevant human cells.[ncbi.nlm.nih.gov]

    Missing: (bromodomain BRD1
  • Respiratory Syncytial Virus

    […] infected with RSV through blockade of the NOD-like receptor protein 3(NLRP3)/apoptosis-associated speck-like protein containing a caspase recruitment domain(ASC)/Caspase-1[ncbi.nlm.nih.gov] We demonstrate that RSV replication induces RelA to complex with bromodomain-containing protein 4 (BRD4), a cofactor required for RNA polymerase II (Pol II) phosphorylation[ncbi.nlm.nih.gov] RESULTS: A severe catarrhal to purulent bronchopneumonia and an interstitial pneumonia were found and human respiratory syncytial virus (HRSV) as well as Streptococcus pneumoniae[ncbi.nlm.nih.gov] These results indicated that V5 VLP vaccine containing tandem repeat gene protein provided better protection than V1 VLPs with significantly decreased inflammation in the[ncbi.nlm.nih.gov] Here, we show that HRSV Matrix (M) protein interacts with the cellular adaptor protein complex 3 specifically via its medium subunit (AP-3Mu3A).[ncbi.nlm.nih.gov] BACKGROUND AND PURPOSE: Protease-activated receptor 1 (PAR1) has been demonstrated to be involved in the pathogenesis of viral diseases.[ncbi.nlm.nih.gov]

    Missing: BRD1
  • Epstein Barr Virus

    Yoshizaki T 1 , Kondo S 1 , Endo K 1 , Nakanishi Y 1 , Aga M 1 , Kobayashi E 1 , Hirai N 1 , Sugimoto H 1 , Hatano M 1 , Ueno T 1 , Ishikawa K 1 , Wakisaka N 1 .[ncbi.nlm.nih.gov] An EP300 bromodomain inhibitor also abolished EBNALP coactivation and blocked the EP300 association with EBNALP.[ncbi.nlm.nih.gov] […] in the human interactome network.[doi.org] Notably, 78% of chronic MS lesions and 33.3% of non-MS brains contained parenchymal CD138 plasma cells.[ncbi.nlm.nih.gov] We have identified a region of EBV DNA, termed oriP (nucleotides 7,333-9,109 of strain B95-8), which acts in cis to permit linked DNAs to replicate as plasmids in cells containing[ncbi.nlm.nih.gov] Structure-function relationships of complement receptor type 1.[ncbi.nlm.nih.gov]

    Missing: BRD1
  • Acute Gastroenteritis

    J Med Virol. 2017 Jan;89(1):17-23. doi: 10.1002/jmv.24593. Epub 2016 Jul 11.[ncbi.nlm.nih.gov] Costs and potential cost savings for the healthcare system should be considered when designing sectorial and cross-sectorial interventions to reduce the burden of human campylobacteriosis[ncbi.nlm.nih.gov] As compared to 0.9% saline, intravenous administration of a dextrose-containing bolus of 0.9% saline is associated with a greater reduction of circulating ketones and a shorter[ncbi.nlm.nih.gov] The result showed that the sample was positive only for enterovirus, and EV-D68 clade B3 was identified by sequence analysis of the viral protein 1 gene.[ncbi.nlm.nih.gov] KEYWORDS: Acute gastroenteritis; clinical features; genotypes; human parechoviruses; prevalence[ncbi.nlm.nih.gov] The sensitivity of GII.17 NoV detection varies by individual test kits and also depending on the amount of the viruses contained in the fecal specimens.[ncbi.nlm.nih.gov]

    Missing: (bromodomain BRD1