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161 Possible Causes for (deaminating, L phenylalanine, and, decarboxylating), oxidase

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  • Dopamine

    Furthermore, the oxidase-like activity of Fe/NC-800 was significantly inhibited by dopamine (DA), leading to blue color fading.[ncbi.nlm.nih.gov] VAP-1 (AOC3) can also deaminate short-chain primary amines. The main end product of DA metabolism is homovanillic acid (HVA), which is excreted to urine by the kidneys .[turkupetcentre.net] L-Phenylalanine (and L-Tyrosine) leads to increased alertness and arousal A peer-reviewed paper published in 2008 concluded that L-Tyrosine and L-Phenylalanine are precursors[naturalstacks.com] The drug is on the WHO official list. dopamine the decarboxylation product of DOPA . Formula: C8H 11 O 2 N.[medical-dictionary.thefreedictionary.com] KEYWORDS: dopamine; hypertension; inotropic agents; linezolid; monoamine oxidase[ncbi.nlm.nih.gov]

    Missing: and
  • Aldehyde

    An inhibition study suggested that monoamine oxidase-B (MAO-B) oxidizes KW-2449 to an iminium (intermediate) and aldehyde oxidase (AO) then metabolizes the intermediate to[ncbi.nlm.nih.gov] […] which inhibits DHPG formation without affecting the deamination of norepinephrine.[ncbi.nlm.nih.gov] Hydrolysis or deprotection Recent Literature A hypervalent iodine reagent, (diacetoxyiodo)benzene, and catalytic amount of sodium azide in acetonitrile enable an oxidative decarboxylation[organic-chemistry.org] KEYWORDS: aldehyde oxidase; animal models; in vitro–in vivo prediction; minipig[ncbi.nlm.nih.gov] Hydrolysis of ester turns it into a β-keto carboxylic acid. β-keto acids undergo decarboxylation because the β-keto group stabilizes the resulting carbanion via enol formation[mcat-review.org]

    Missing: L phenylalanine and
  • Norepinephrine

    DHPG is formed when norepinephrine is incubated with aldose reductase in the presence of monoamine oxidase.[ncbi.nlm.nih.gov] The amino acid supplements L-tyrosine and L-phenylalanine increase norepinephrine production, but must be used cautiously, especially if you are bipolar, according to Emmons[livestrong.com] This is followed by decarboxylation into the neurotransmitter dopamine. Last is the final β-oxidation into norepinephrine by dopamine beta hydroxylase.[newworldencyclopedia.org] -DOPS) Etilevodopa Ephedrine Ergotamine Epinephrine Etilefrine Ethylnorepinephrine Guanabenz Guanfacine Guanoxabenz L -DOPA (levodopa) L -Phenylalanine L -Tyrosine Lofexidine[en.wikipedia.org] Up to 16% of an intravenous dose is excreted unchanged in the urine with methylated and deaminated metabolites in free and conjugated forms.[medicines.org.uk]

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  • Pargyline

    Abstract During 4 weeks of treatment with clorgyline, a selective MAO-A inhibitor, platelet monoamine oxidase (MAO) activity was unchanged.[ncbi.nlm.nih.gov] […] of lnorepinephrine dopamine and serotonin 517 Oxidative deamination of trace amines in the brain A A Boulton B A Davis D 539 Platelet MAO activity in depressed patients Jean[books.google.com] -DOPA (levodopa) Dopamine 5-HTP Serotonin L -Histidine Histamine Phenylalanine Phenethylamine L -Tyrosine Tyramine Tryptophan Tryptamine Inhibitors: Benserazide Carbidopa[en.wikipedia.org] The volume presents a collection of research papers on monoamine oxidase and its inhibitors.[books.google.com] MAO-A preferentially deaminates serotonin, melatonin, epinephrine and norepinephrine. MAO-B preferentially deaminates phenylethylamine and trace amines.[drugbank.ca]

    Missing: and decarboxylating)
  • Histidinemia

    Cause & Clinical: without Homogenitase oxidase intermediate product: homogenitasic acid will increase URINE. later, black pigment in cartilage and other connective tissues[quizlet.com] Abstract Histidase (histidine ammonia-lyase, EC 4.3.1.3) catalyzes the deamination of L-histidine to trans-urocanic acid in the liver and skin of mammals.[ncbi.nlm.nih.gov] These results suggest that hyperhistaminemia is not due to allergic reactions but results from increased decarboxylation of histidine.[ncbi.nlm.nih.gov] […] biochemical, and neuropsychiatric evaluation of a patient with a contiguous gene syndrome due to a microdeletion Xp11.3 including the Norrie disease locus and monoamine oxidase[books.google.ro] Many of the central nervous system (CNS) effects observed seem to be caused by decarboxylation of l-histidine to histamine within the CNS.[pharmacologicalsciences.us]

    Missing: L phenylalanine and
  • Chloroquine

    METHODS: Differential metabolism of PQ enantiomers by recombinant human CYP2D6, monoamine oxidase A (MAO), and cryopreserved human hepatocytes in the presence/absence of CQ[ncbi.nlm.nih.gov] Oxytetracycline, Molecular Formula of Omeprazole, Oxyphenbutazone, Pancuronium Bromide, Paracetamol, Papaverine, Penicilling, Pentazocine, Synonyms of Pentoxifylline, Synonyms of L-Phenylalanine[books.google.es] The formation of the primary deaminated metabolites, including carboxyprimaquine (CPQ) and cyclized side chain derivative from the aldehyde (m/z 241), was not sensitive to[ncbi.nlm.nih.gov]

    Missing: and decarboxylating)
  • Molindone

    Despite these similarities, molindone also has atypical properties and inhibits the enzyme monoamine oxidase in vitro and in vivo.[ncbi.nlm.nih.gov] 24 h pretreatment with molindone enhanced the behavioural effects of L-dopa and 5-HTP, precursors of biogenic amines (catecholamines and 5-HT respectively) preferentially deaminated[ncbi.nlm.nih.gov] -DOPA (levodopa) Melevodopa L -Phenylalanine L -Tyrosine XP21279 Others A-68930 Apomorphine Isocorypalmine Nuciferine Propylnorapomorphine Rotigotine SKF-89,145 SKF-89,626[ipfs.io] -DOPA (levodopa) Melevodopa L -Phenylalanine L -Tyrosine XP21279 Others : A-68930 Apomorphine Isocorypalmine Nuciferine PF-6649751 PF 6669571 Propylnorapomorphine Rotigotine[en.wikipedia.org] -DOPA (levodopa) L -Phenylalanine L -Tyrosine Melevodopa XP21279 Atypical antipsychotics Alentemol (U-66444B) Aripiprazole ( sertraline) Aripiprazole lauroxil Bifeprunox Brexpiprazole[ipfs.io]

    Missing: and decarboxylating)
  • Methyldopa

    […] decrease sympathetic nervous system outflow. indications It is prescribed for the reduction of hypertension in moderate to severe cases. contraindications Use of monoamine oxidase[medical-dictionary.thefreedictionary.com] -DOPS) Etilevodopa Ephedrine Ergotamine Epinephrine Etilefrine Ethylnorepinephrine Guanabenz Guanfacine Guanoxabenz L -DOPA (levodopa) L -Phenylalanine L -Tyrosine Lofexidine[en.wikipedia.org] We conclude that OR-611 prolongs the circulation time of FDOPA in the plasma but does not alter rate constants for striatal FDOPA uptake or decarboxylation.[ncbi.nlm.nih.gov] This review outlines the mechanisms of adrenergic control of the circulation and how the proposed mechanisms of action of methyldopa (ie, dopa decarboxylation, false neurotransmission[jamanetwork.com] Additional studies demonstrated that the rat microsomal system could be replaced by human hepatic microsomes or by a xanthine oxidase system and the binding was again inhibited[molpharm.aspetjournals.org]

    Missing: (deaminating and
  • Catha Edulis

    Abstract The possibility that phenylalkylamines (cathinone and cathine) of khat, like amphetamines, are amine oxidase inhibitors with clinical significance is evaluated.[ncbi.nlm.nih.gov] These secondary metabolites are produced in planta through a L-phenylalanine derived multi-step pathway.[prism.ucalgary.ca] These two distantly related enzymes (Green, 1989) share the common step of pyruvate decarboxylation.[scielo.br] In contrast with AHAS, carboligation is only a minor side reaction for PDC; the latter enzyme largely performs pyruvate decarboxylation to form acetaldehyde and CO 2 .[journals.plos.org] Theoretically, concurrent use of khat with monoamine oxidase inhibitors may cause hypertensive (high blood pressure) crisis.[livingnaturally.com]

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  • Endogenous Depression

    Treatment of Mild Endogenous Depression with a Mono-amine Oxidase Inhibitor: A Controlled Trial in General Practice Ian R. McWhinney , D. C.[bjgp.org] The specificity of brofaromine to inhibit deamination is limited to MAO-A, since no reduction in platelet MAO activity was measurable.[ncbi.nlm.nih.gov] The below I take everyday: l-dopa (300 mg) Bacopa (250 mg) 5-HTP (100 mg) Rhodiola Rosea (250 mg) Holy Basil (575 1150 mg) Maca Root (500 mg) l-phenylalanine (500 mg) l-lysine[drugs-forum.com] Recently, a new generation of monoamine oxidase (MAO) inhibitors has been developed which selectively and reversibly inhibit MAO-A activity. 2.[ncbi.nlm.nih.gov]

    Missing: and decarboxylating)