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979 Possible Causes for (heart), Purkinje, system

  • Hypoxic-Ischemic Encephalopathy

    The relationships between heart rate variability measures and esophageal/axillary temperatures were evaluated.[ncbi.nlm.nih.gov] In contrast to the relative sparing of Betz cells, Purkinje cells of the cerebellar cortex were totally destroyed.[ncbi.nlm.nih.gov] OBJECTIVES: To establish the validity of the MRI scoring system with neurodevelopmental outcome at 18-24 months.[ncbi.nlm.nih.gov]

  • Heart Failure

    Heart failure can also be caused by: Damaged or diseased heart valves An abnormal heart rhythm (arrhythmia) Congenital heart conditions – heart problems that you’re born with[bhf.org.uk] These are the atrioventricular node, “bundle of His” and “Purkinje fibres” – all can cause the heart to beat, but at a slower rate than the sinoatrial node.[theconversation.com] The CardioMEMS System detected a gradual but steady increase in the pulmonary artery pressures while the patient was completely asymptomatic.[ncbi.nlm.nih.gov]

  • Heart Block

    Third degree heart block (Complete heart block) The most serious type of heart block is third degree.[symptoma.com] In these cases, the His-Purkinje system's conductive capacity is progressively deranged, involving either right or left bundle branch block.[ncbi.nlm.nih.gov] She had a history of arthralgias and antinuclear antibodies but no clinical history of systemic lupus erythematosus.[ncbi.nlm.nih.gov]

  • Minamata Disease

    […] autonomic nervous functions in patients with fetal type Minamata disease (FMD), we investigated blood pressure (BP), and conducted time and frequency domain analysis of heart[ncbi.nlm.nih.gov] Bergmann's glial cells also contained mercury deposits, whereas Purkinje's cells had relatively little or no deposition.[ncbi.nlm.nih.gov] We report here a case with description of the distribution of mercury in the systemic organs, and the ultrastructural changes of the nervous system after a survival of 29[ncbi.nlm.nih.gov]

  • Perhexiline

    INTRODUCTION: The re-purposing of the anti-anginal drug perhexiline (PHX) has resulted in symptomatic improvements in heart failure (HF) patients.[ncbi.nlm.nih.gov] Its action in concentrations of 3 and 6 mcg/ml on the transmembrane action potentials in isolated Purkinje fibers has also been analyzed.[ncbi.nlm.nih.gov] The method used protein precipitation with acetonitrile followed by dilution with water and subsequent direct injection of the extract into the LC-MS system.[ncbi.nlm.nih.gov]

  • Carnitine Deficiency

    Abstract A newborn male presenting with congenital complete heart block was found to have low levels of free plasma carnitine.[ncbi.nlm.nih.gov] Electron microscopy revealed mitochondrial abnormalities in skeletal and cardiac muscle and also in the Purkinje cells.[ncbi.nlm.nih.gov] Abstract A patient with pericardial effusion and a complicated presentation of primary systemic carnitine deficiency (PSCD) is described.[ncbi.nlm.nih.gov]

  • Dilated Cardiomyopathy

    BACKGROUND: Heart rate reduction as a therapeutic target has been investigated in adults with heart failure (HF).[ncbi.nlm.nih.gov] Recently, SCN5A mutations have been linked to the clinical entity multifocal ectopic Purkinje-related premature contractions (MEPPC) characterized by ventricular ectopy and[ncbi.nlm.nih.gov] Despite these complications, there are multiple promising implications of systems analysis in DCM.[ncbi.nlm.nih.gov]

  • Restrictive Cardiomyopathy

    BACKGROUND: Some cancer therapies can cause advanced heart failure requiring heart transplantation.[ncbi.nlm.nih.gov] BACKGROUND: Desmin is an intermediate filament normally present in the myocardium, particularly in the Purkinje fibres, in the skeletal and in the smooth muscle.[ncbi.nlm.nih.gov] KEYWORDS: cardiomyopathy; hydroxychloroquine; restrictive cardiomyopathy; systemic lupus erythematosus[ncbi.nlm.nih.gov]

  • Idiopathic Ventricular Fibrillation

    To address the question whether the S-ICD system is safe and feasible for young patients with electrical heart disease or idiopathic ventricular fibrillation (VF), the data[ncbi.nlm.nih.gov] Triggers of ventricular fibrillation originated from various locations within the Purkinje system in 12 patients and from the ordinary myocardial muscle in four.[ncbi.nlm.nih.gov] Radiofrequency catheter ablation was performed, targeting the distal Purkinje system.[ncbi.nlm.nih.gov]

  • Isoproterenol

    Human response to isoproterenol induced cardiac injury was evaluated by gene and protein pathway changes in human heart slices, and compared to rat heart slices and rat heart[ncbi.nlm.nih.gov] Isoproterenol precipitated classic 2:1 Infra-Hisian AV block most probably proximal to the site of recording a His-Purkinje potential consistent with right bundle branch activity[ncbi.nlm.nih.gov] Unexpectedly, we found that isoproterenol and cholera toxin exhibited distinct effects in acute lethal systemic inflammatory response.[ncbi.nlm.nih.gov]