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4,395 Possible Causes for (hypercalcemia), 5, CTCAE, Calcium,, Grade, serum high

Did you mean: (hypercalcemia, 5, CTCAE, Calcium, Grade, serum high

  • Hypercalcemia of Malignancy

    This CSC level corresponds to a grade 3 (severe) adverse event on the Common Terminology Criteria for Adverse Events (CTCAE) scale ( 21 ).[academic.oup.com] RESULTS: Among 37,442 cancer patients in 2003-2012 the prevalence of grade 1 HCM increased from 0.13% to 0.45% and the prevalence of HCM overall (grade 1 or higher) increased[ncbi.nlm.nih.gov] CONCLUSION: In this case, the carcinoma cells had already produced PTH-rP in the primary tumor although the serum calcium levels had not been significantly high at surgery[ncbi.nlm.nih.gov] Abstract The etiology, pathophysiology, and diagnosis of hypercalcemia associated with malignant diseases are discussed.[ncbi.nlm.nih.gov] Implementation of calcium-free hemodialysis resulted in a rapid reduction of the serum calcium from 22.6 mg/dl to 11.6 mg/dl.[ncbi.nlm.nih.gov] Wright JD 1, 2, 3 , Tergas AI 1, 2, 3, 4 , Ananth CV 1, 4 , Burke WM 1, 2, 3 , Hou JY 1, 2, 3 , Chen L 1 , Neugut AI 2, 3, 4, 5 , Richards CA 4 , Hershman DL 2, 3, 4, 5 .[ncbi.nlm.nih.gov]

  • Renal Cell Carcinoma

    Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0. 2010 ( ). 21. Cella D, Yount S, Brucker PS, et al.[doi.org] Whole tumor Fuhrman grading was grade 1, 6 cases; grade 2, 72 cases; grade 3, 8 cases; and grade 4, 1 case, whereas focal (single high power field) grading was grade 1, 1[doi.org] […] lactate dehydrogenase ( 1.5 upper limit of normal), low serum hemoglobin (less than the lower limit of normal), high corrected serum calcium ( 10 mg/dL), and absence of prior[doi.org] Google Scholar 7 : A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression . Science 1987 ; 237 : 893.[doi.org] Western blot analysis of cadherin-5.[doi.org] Common Terminology Criteria for Adverse Events (CTCAE), version 4.0. June 14, 2010 ( ). 20. Clopper CP . ES.[nejm.org]

  • Osteoporosis

    Evidence was graded according to the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system.[ncbi.nlm.nih.gov] Bone mineral density and serum testosterone in chronically trained, high mileage 40–55 year old male runners K J MacKelvie , J E Taunton , H A McKay , K M Khan School of Human[doi.org] Abstract Zoledronate is a Nitrogen containing bisphosphonate (NBP) used in many conditions like osteoporosis, Paget's disease and hypercalcemia of malignancy.[ncbi.nlm.nih.gov] It is known that a normal calcium balance together with a normal vitamin D status is important for maintaining well-balanced bone metabolism, and for many years, calcium and[ncbi.nlm.nih.gov] Stopping therapy after 5 years is thought to be reasonable, because there appears to be a residual benefit on BMD and fractures for up to another 5 years.[web.archive.org] None of the patients developed hypercalcemia. During teriparatide therapy, 3patients underwent a flare or a complication of sarcoidosis.[ncbi.nlm.nih.gov]

    Missing: CTCAE
  • Multiple Myeloma

    Common terminology criteria for adverse events (CTCAE), version 4.03 ( ). 13. Axel AE, McCudden CR, Xie H, Hall BM, Sasser AK.[doi.org] However, hypercalcemia secondary to multiple myeloma as a major cause of paralytic ileus has rarely been reported.[ncbi.nlm.nih.gov] However, the role of store-operated calcium entry (SOC) channels, the only Ca2 channels of non-excitable cells, has not yet been reported in MM cell survival.[ncbi.nlm.nih.gov] Blood. 2001; 97 :1566–71. [ PubMed ] [ Google Scholar ] 5. Durie BGM, Kyle RA, Belch A, et al.[doi.org] In addition, the use of carfilzomib significantly increased all-grade (Peto OR 2.33, 95% CI: 1.56-3.48, p p p 0.30) and high-grade (Peto OR 1.41, 95% CI: 0.73-2.72, p 0.31[ncbi.nlm.nih.gov] Instead, high levels of serum and ascitic vascular endothelial growth factor were detected.[ncbi.nlm.nih.gov]

  • Calcium Gluconate

    Throughout therapy, you should observe the patient for signs of hypocalcemia or hypercalcemia.[nclexpreceptor.com] [ edit ] 10% calcium gluconate solution (given intravenously ) is the form of calcium most widely used in the treatment of low blood calcium.[en.wikipedia.org] InChIKey KYUVBRZSDFBLTH-OSQBQZLYSA-M CAS DataBase Reference 299-28-5(CAS DataBase Reference) EPA Substance Registry System D-Gluconic acid, calcium salt (2:1)(299-28-5) SAFETY[chemicalbook.com] Unfortunately, there is a small population of patients who develop grade III/IV hypersensitivity reactions to oxaliplatin which, until recently, have interfered with further[ncbi.nlm.nih.gov] It is particularly important to prevent a high concentration of calcium from reaching the heart because of the danger of cardiac syncope.[rxmed.com] Muscle pains were graded according to severity as nil, mild, moderate, and severe.[ncbi.nlm.nih.gov]

    Missing: CTCAE
  • Hypomagnesemia

    Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0 – hypomagnesemia grading scale. Saif, M.W. (2008).[theonc.org] Causes include inadequate magnesium intake and absorption or increased excretion due to hypercalcemia or drugs such as furosemide .[merckmanuals.com] Serum calcium normalized with administration of calcitriol and calcium carbonate. Serum magnesium improved with oral magnesium sulfate.[ncbi.nlm.nih.gov] Chardain A 1 , Mesnage V 2 , Alamowitch S 2 , Bourdain F 3 , Crozier S 4 , Lenglet T 5 , Psimaras D 5 , Demeret S 6 , Graveleau P 3 , Hoang-Xuan K 5 , Levy R 2 .[ncbi.nlm.nih.gov] RESULTS: The incidence rates of hypomagnesemia and acneiform rash were 32.6 % (grade 1: 20.9 %, grade 2: 11.6 %) and 93.0 % (grade 1: 41.9 %, grade 2: 41.9 %, grade 3: 9.3[ncbi.nlm.nih.gov] By contrast, hypermagnesemia is an abnormally high level of magnesium. Hypomagnesemia occurs when serum values drop below 1.5 mg/dL.[study.com]

  • Vitamin D

    […] the Expanded Disability Status Scale at 52 weeks' follow-up (MD -0.25, 95% CI -0.61 to 0.10; I² 35%; five trials; 221 participants; very low-quality evidence according to GRADE[ncbi.nlm.nih.gov] Vitamin D supplementation were found to significantly reduce serum high-sensitivity C-reactive protein (hs-CRP) (WMD 0.27; 95% CI, - 0.35, - 0.20; p Georg Thieme Verlag KG[ncbi.nlm.nih.gov] Prednisolone treatment improved the hypercalcemia and decreased the levels of 1,25(OH) 2 D and IL-6. We first reported a case of vitamin D-mediated hypercalcemia in MCD.[ncbi.nlm.nih.gov] For breast cancer, calcium intakes in premenopausal women were associated with a decreased risk.[ncbi.nlm.nih.gov] Mackerel — 3 ounces: 306 IU (76 percent DV) 5. Tuna Fish — 3 ounces: 154 IU (39 percent DV) 6. Fortified Milk — 1 cup: 124 IU (31 percent DV) 7.[draxe.com] VDBP, high-sensitivity C-reactive protein (hs-CRP), and insulin resistance in these patients.[ncbi.nlm.nih.gov]

    Missing: CTCAE
  • Hyperparathyroidism

    Hypercalcemia Symptoms and Signs Hypercalcemia is a condition in which blood calcium levels are elevated.[medicinenet.com] calcium.[doi.org] Bellido V 1, 2 , Larrañaga I 3 , Guimón M 3 , Martinez-Conde R 4 , Eguia A 4 , Perez de Nanclares G 5, 6 , Castaño L 7, 5, 6, 8 , Gaztambide S 3, 7, 5, 6, 8 .[ncbi.nlm.nih.gov] Grade C Google Scholar Medline ISI[doi.org] This patient had had symptomatic secondary hyperparathyroidism with diffuse skeletal pain, hypercalcemia, and high serum parathyroid hormone concentrations.[doi.org] High concentrations of serum calcium inhibit PTH secretion, while low concentrations stimulate it.[patient.info]

    Missing: CTCAE
  • Parathyroid Carcinoma

    It may also be of potential use in settings of benign hyperparathyroid-related hypercalcemia such as parathyromatosis, where hypercalcemia is not amenable to surgery or medical[ncbi.nlm.nih.gov] PTH helps the body maintain normal levels of serum calcium by promoting calcium reabsorption from bone.[en.wikipedia.org] RESULTS: The 5-year OS was 81.1% in 528 patients with 60 months of follow-up.[ncbi.nlm.nih.gov] The patient underwent surgery, and histopathology revealed a low-grade parathyroid carcinoma.[ncbi.nlm.nih.gov] This helps to differentiate between the parathyroid dependant and independent causes of high serum calcium, thereby encouraging a comprehensive pathway to the work up of the[ncbi.nlm.nih.gov] Also called high-grade lymphoma and intermediate-grade lymphoma. aggressive systemic mastocytosis listen (uh-GREH-siv sis-TEH-mik MAS-toh-sy-TOH-sis) A rare condition in which[cancer.gov]

    Missing: CTCAE
  • Nephrocalcinosis

    […] hyperthyroidism was associated with hypercalcemia, nephrocalcinosis and renal insufficiency.[nejm.org] The major causes include those associated with an increase in urinary levels of calcium, oxalate and phosphate.[dx.doi.org] Nephrocalcinosis is a topic covered in the 5-Minute Clinical Consult.[unboundmedicine.com] Of nephrocalcinosis seen on US and not CT, 45%, 46%, and 9% were grades 1, 2, and 3, respectively.[ncbi.nlm.nih.gov] All patients had a typical pattern of test results, including normal-high serum calcium, low parathyroid hormone levels, high vitamin D 25-(OH)D3 and 1,25-(OH)2D3, and low[ncbi.nlm.nih.gov] Accessory salivary gland biopsy showed Grade 2 inflammatory infiltrates on the Chisholm–Mason scale.[ckj.oxfordjournals.org]

    Missing: CTCAE

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