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2,697 Possible Causes for 1, CAAX, MOTIF, PROTEIN, RIC LIKE, WITHOUT

Did you mean: 1, CAAX, miotic, proteus, RIC LIKE, WITHOUT

  • Phenothiazine

    Sigma 1 receptors are associated with neurodegenerative and psychiatric disorders.[ncbi.nlm.nih.gov] FPTE without an evaporation step was the only method that did not measurably induce analyte oxidation.[ncbi.nlm.nih.gov] A new family of CaaX competitive inhibitors of human farnesyltransferase based on phenothiazine and carbazole skeleton bearing a l-cysteine, l-methionine, l-serine or l-valine[ncbi.nlm.nih.gov] A new family of protein farnesyltransferase inhibitors, based on a phenothiazine scaffold, was designed and synthesized.[ncbi.nlm.nih.gov] The modest results obtained in this preliminary investigation showed that mixing the phenothiazine and the 1,2,3-triazole motif in the structure of a single compound can lead[ncbi.nlm.nih.gov] Patients presenting with dystonias were more likely to have extensive diagnostic testing for neurologic disease than those presenting without dystonias.[ncbi.nlm.nih.gov]

    Missing: RIC LIKE
  • Entamoeba Histolytica

    Our results demonstrate that EhRab7A is localized on the phagosomes and involved in both early and late stages of type 1 E. coli phagocytosis.[ncbi.nlm.nih.gov] The mean prevalence rate of E. histolytica/dispar was significantly higher among individuals with GE compared with those without GE (p 0.0000001, OR 2.74).[ncbi.nlm.nih.gov] Here, we reported that the EhPRL protein possessed the classical HCX5R catalytic motif of PTPs and the CAAX box characteristic of the PRL family and exhibited 31-32% homology[ncbi.nlm.nih.gov] EhADH emerged as an extended peripheral membrane protein with high fluctuation in Bro1 and V shape domains. 500 ns-long MDS and protein-protein docking predictions evidenced[ncbi.nlm.nih.gov] It also appears from modelling of the EhCaBP5-IQ motif complex that EhCaBP5 undergoes a structural change in order to bind the IQ motif of myosin.[ncbi.nlm.nih.gov] We surveyed the prevalence of Dientamoeba fragilis, Giardia duodenalis, Entamoeba histolytica, Entamoeba dispar, and Cryptosporidium spp in individuals with and without gastrointestinal[ncbi.nlm.nih.gov]

    Missing: RIC LIKE
  • Influenza

    The seroprotection rate was defined in 2 ways as the proportion of subjects who achieved an antibody titer of 1:40 or 1:160.[ncbi.nlm.nih.gov] Sequence based analysis demonstrated substantial changes in the HA protein over the last decade.[ncbi.nlm.nih.gov] We report a case of Henoch-Schonlein purpura (HSP) presenting without typical skin lesion; atypical symptoms initially appeared following influenza infection.[ncbi.nlm.nih.gov] Feature key Position(s) Description Actions Graphical view Length Motif i 124 – 139 Nuclear localization signal 1 (NLS1) Add BLAST 16 Motif i 184 – 247 Nuclear localization[uniprot.org] Endomyocardial biopsy results yielded myocardial necrosis through complement-mediated cellular injury without evidence of interstitial infiltrates.[ncbi.nlm.nih.gov] The clinical manifestation and initial lesion on brain DWI mimicked top of basilar syndrome, but without an arterial occlusion or stenosis.[ncbi.nlm.nih.gov]

    Missing: CAAX RIC LIKE
  • Episodic Ataxia

    This review examines our current understanding of episodic ataxia type 1, focusing on its clinical and genetic features, pathophysiology, and treatment.[ncbi.nlm.nih.gov] This mutation leads to a distinct clinical phenotype without myokymia broadening the scope of clinical characteristics of EA1 and highlighting the heterogeneity of phenotypic[ncbi.nlm.nih.gov] Suppression was enhanced by tethering the N terminus to the membrane with a CAAX motif.[ncbi.nlm.nih.gov] I262T appears to be the first EA1 mutation directly associated with impaired protein stability.[ncbi.nlm.nih.gov] […] year-old woman consulted the headache clinic because of frequent paroxysmal attacks of strong sensoriphobia, digestive signs, moderate ataxia and a need to lie in the dark, without[ncbi.nlm.nih.gov] At least two groups of disorders have been separated clinically: (1) episodic ataxia type 1 (EA-1), which manifests without vertigo and is associated with 'interictal' myokymia[ncbi.nlm.nih.gov]

    Missing: RIC LIKE
  • Zellweger Syndrome

    Other reported cases of UPD1, and evidence for the imprinting of genes on chromosome 1, are reviewed.[ncbi.nlm.nih.gov] In summary, a mild variant of the classical cerebro-hepato-renal syndrome of Zellweger was found without the characteristic clinical facial signs.[ncbi.nlm.nih.gov] This cDNA encodes a hydrophilic protein (Pex19p) comprising 299 amino acids, with a prenylation motif, CAAX box, at the C terminus.[ncbi.nlm.nih.gov] We present the developmental changes of peroxisomal enzymes, catalase, L-bifunctional protein (L-BF) and D-bifunctional protein (D-BF), in the normal brains, and patients[ncbi.nlm.nih.gov] In this study, we performed localized in vivo proton MRS without confounding contributions from T1- and T2-relaxation effects at 2 Tesla in a comparably large group of seven[ncbi.nlm.nih.gov] This cDNA encodes a 359-amino-acid membrane protein of peroxisomes with two transmembrane segments and a cysteine-rich zinc finger, the RING motif.[ncbi.nlm.nih.gov]

    Missing: RIC LIKE
  • Colorectal Carcinoma

    Lentiviral- encoding Notch‑1‑siRNA, as well as Notch‑1 inhibitor was employed to silence Notch‑1 expression and to inhibit Notch‑1 activity in HT29 cells, respectively.[ncbi.nlm.nih.gov] […] this pathology and highlight the importance of continual, vigilant radiological surveillance of the adrenal glands after curative treatment of colorectal carcinoma with or without[ncbi.nlm.nih.gov] As an end-proteolytic enzyme that cleaves the last three residues of proteins with a terminal CAAX, Ras-converting enzyme 1 (RCE1) has an essential role in multiple signaling[ncbi.nlm.nih.gov] Ligand-of-Numb protein X1 (LNX1) is one E3 ubiquitin ligase which mediates the ubiquitination and degradation of Numb.[ncbi.nlm.nih.gov] A CpG motif and interleukin-2 (IL-2) cytokine are often used as adjuvants.[ncbi.nlm.nih.gov] We report a case of triple synchronous colorectal carcinoma without related familial history.[ncbi.nlm.nih.gov]

    Missing: RIC LIKE
  • Juvenile Myelomonocytic Leukemia

    We present the rare finding of a 7-year-old girl with NF-1 who developed JMML. She inherited her NF-1 from the father.[ncbi.nlm.nih.gov] A-kinase anchor protein 12 (AKAP12) is a regulator of protein kinase A and protein kinase C signaling, acting downstream of RAS.[ncbi.nlm.nih.gov] Here we report that two JMML patients survived 20 years without HSCT and both patients had uniparental disomy of 11q23 where CBL is located without the phenomenon found in[ncbi.nlm.nih.gov] Recently, RIT1 (Ras-like without CAAX 1) has been shown to be involved in the pathogenesis of some patients.[ncbi.nlm.nih.gov] […] for small G proteins, as a recurrent target of isoform-specific DNA hypermethylation in JMML (51% of 125 patients analyzed).[ncbi.nlm.nih.gov] Further efforts toward identifying which patients who will do well without HSCT are required.[ncbi.nlm.nih.gov]

    Missing: RIC LIKE
  • Herpes Simplex Virus 1

    The Us11 protein of herpes simplex virus 1 (HSV-1) is an accessory factor with multiple functions.[ncbi.nlm.nih.gov] Nineteen patients with HSV-1/2 viremia and fifty-seven patients without HSV-1/2 viremia which were selected using the case-pair method after undergoing haploidentical HSCT[ncbi.nlm.nih.gov] During viral infection, accumulation of viral proteins can cause stress in the endoplasmic reticulum (ER) and trigger the unfolded protein response (UPR) to restore ER homeostasis[ncbi.nlm.nih.gov] (i) A SUMO interaction motif located at ICP0 residues 362 to 364 is required for the degradation of PML isoforms II, IV, and VI but not isoform I.[ncbi.nlm.nih.gov] We show that PIAS1 localizes at PML-NBs in a SUMO interaction motif (SIM)-dependent manner that requires SUMOylated or SUMOylation-competent PML.[ncbi.nlm.nih.gov] Herpes simplex virus-1 (HSV-1) causes lifelong recurrent pathologies without a cure.[ncbi.nlm.nih.gov]

    Missing: CAAX RIC LIKE
  • Lysinuric Protein Intolerance

    , in 31 Finnish LPI patients and 1 Spanish patient.[ncbi.nlm.nih.gov] Lysinuric protein intolerance (LPI), also called hyperdibasic aminoaciduria type 2 , cationic aminoaciduria or familial protein intolerance , is an autosomal recessive [1][en.wikipedia.org] Many of the patients had recurrent mild normochromic anaemia without apparent iron deficiency, and leuko- and/or thrombocytopenia.[ncbi.nlm.nih.gov] Noteworthy, the p.R333M mutation, caused by a G to T transversion of the last nucleotide at 3' end of exon 7, disrupts a functional splicing motif generating misspliced transcripts[ncbi.nlm.nih.gov] However, she gave birth to a normal child without serious maternal complications.[ncbi.nlm.nih.gov] A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. ‎[books.google.com]

    Missing: CAAX RIC LIKE
  • Taenia Solium

    Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns.[ncbi.nlm.nih.gov] But there have been no clinical reports of ascites, chronic diarrhea, and malabsorption due to Taenia solium without evidence of the ova or larvae of the parasites in stool[ncbi.nlm.nih.gov] Subsequent proteome analysis of CC-Fas binary complex mediated protein-protein interactions revealed seven protein ligands in the TsM cellular proteins.[ncbi.nlm.nih.gov] The enzyme belongs to the short chain dehydrogenases/reductase family and shares motifs and activity with the type 3 enzyme of some other species.[ncbi.nlm.nih.gov] All 20 tapeworms except one without scolex were expelled under good conditions. She was free of secondary cysticercosis within one year follow up.[ncbi.nlm.nih.gov] In phase 2, we compared mass treatment with mass screening (each either with or without vaccination of pigs) in 17 villages.[ncbi.nlm.nih.gov]

    Missing: CAAX RIC LIKE