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9,065 Possible Causes for 1, Dromyosuppressin, Drosophila, protein,, receptor

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  • Influenza

    IL-1 receptor (IL-1R1).[doi.org] […] recognizing SAα2,3Gal can be transmitted from birds to humans, they can replicate efficiently only in cells in the lower region of the respiratory tract, where the avian-virus receptor[doi.org] Adaptive evolution drives divergence of a hybrid inviability gene between two species of Drosophila . Nature 423 , 715–719 (2003) 12 Webster, R. G., Bean, W.[doi.org] Like hemagglutinin and neuraminidase, the M2 protein is an integral membrane protein of the influenza A virus 4 , 5 .[doi.org] Electron density of the receptors.[doi.org]

    Missing: Dromyosuppressin
  • Spinal and Bulbar Muscular Atrophy

    The patient had the characteristic clinical findings of SBMA, but none of myotonic dystrophy type 1 (DM1).[ncbi.nlm.nih.gov] We were unable to find androgen receptor (AR) in the scrotal skin of three patients with SBMA, and propose that AR abnormality is the cause of the disease.[ncbi.nlm.nih.gov] Gov't MeSH terms Animals COS Cells Cercopithecus aethiops Drosophila Drosophila Proteins/genetics* Drosophila Proteins/metabolism HEK293 Cells Humans Mice Muscular Disorders[ncbi.nlm.nih.gov] Here, we show that in culture insulin-like growth factor 1 (IGF-1) reduces AR aggregation and increases AR clearance via the ubiquitin-proteasome system through phosphorylation[ncbi.nlm.nih.gov] Abstract Polyglutamine expansion within the androgen receptor (AR) causes spinal and bulbar muscular atrophy (SBMA) and is associated with misfolded and aggregated species[ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin
  • Congenital Myasthenic Syndrome

    AU - Brengman, Joan AU - Selcen, Duygu AU - Engel, Andrew G PY - 2017/2/1 Y1 - 2017/2/1 N2 - Objective: To identify the molecular basis and elucidate the pathogenesis of a[mayoclinic.pure.elsevier.com] […] that severely reduce endplate acetylcholine receptor numbers and/or cause kinetic abnormalities of acetylcholine receptor function.[ncbi.nlm.nih.gov] Our Drosophila studies support a role for this synaptotagmin point mutation in disease etiology.[ncbi.nlm.nih.gov] Most CMS stem from molecular defects in the muscle nicotinic acetylcholine receptor, but they can also be caused by mutations in presynaptic proteins, mutations in proteins[ncbi.nlm.nih.gov] Further functional analysis revealed instability of the protein and impaired clustering of the acetylcholine receptor (AChR) by both mutations.[ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin
  • Spinocerebellar Ataxia Type 1

    […] type 1.[symptoma.com] In this study, we report progressive dysfunction of metabotropic glutamate receptor (mGluR) signalling, which leads to smaller slow synaptic responses, reduced dendritic Ca2[ncbi.nlm.nih.gov] We applied this approach, which integrates parallel cell-based and Drosophila genetic screens, to spinocerebellar ataxia type 1 (SCA1), a disease caused by expansion of a[ncbi.nlm.nih.gov] Here we show that the expanded polyglutamine tract differentially affects the function of the host protein in the context of different endogenous protein complexes.[ncbi.nlm.nih.gov] The association of ataxin-1 with 14-3-3 is regulated by Akt phosphorylation, and in a Drosophila model of SCA1, both 14-3-3 and Akt modulate neurodegeneration.[ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin
  • Congenital Myasthenic Syndrome

    AU - Brengman, Joan AU - Selcen, Duygu AU - Engel, Andrew G PY - 2017/2/1 Y1 - 2017/2/1 N2 - Objective: To identify the molecular basis and elucidate the pathogenesis of a[mayoclinic.pure.elsevier.com] […] that severely reduce endplate acetylcholine receptor numbers and/or cause kinetic abnormalities of acetylcholine receptor function.[ncbi.nlm.nih.gov] Our Drosophila studies support a role for this synaptotagmin point mutation in disease etiology.[ncbi.nlm.nih.gov] Most CMS stem from molecular defects in the muscle nicotinic acetylcholine receptor, but they can also be caused by mutations in presynaptic proteins, mutations in proteins[ncbi.nlm.nih.gov] Further functional analysis revealed instability of the protein and impaired clustering of the acetylcholine receptor (AChR) by both mutations.[ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin
  • Fibrodysplasia Ossificans Progressiva

    Fujimoto M 1 , Ohte S 2 , Shin M 2 , Yoneyama K 2 , Osawa K 2 , Miyamoto A 2 , Tsukamoto S 2 , Mizuta T 2 , Kokabu S 2 , Machiya A 1 , Okuda A 3 , Suda N 4 , Katagiri T 5[ncbi.nlm.nih.gov] Gov't MeSH terms Activin Receptors, Type I/antagonists & inhibitors Activin Receptors, Type I/chemistry* Activin Receptors, Type I/genetics Activin Receptors, Type I/metabolism[ncbi.nlm.nih.gov] RESULTS: In Drosophila, human ALK2(R206H) receptor induces hyperactive BMP signaling.[ncbi.nlm.nih.gov] The FOP knock-in mouse and other models in Drosophila, zebrafish, chickens and mice provide an arsenal of tools for understanding BMP signaling and addressing outstanding[ncbi.nlm.nih.gov] Pang J 1 , Zuo Y 1 , Chen Y 2 , Song L 1 , Zhu Q 1 , Yu J 1 , Shan C 1 , Cai Z 2 , Hao J 3 , Kaplan FS 4 , Shore EM 4 , Zhang K 5 .[ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin
  • Coxsackie Virus

    (HLA-DR3-DQ2 or HLA-DR4-DQ8) for type 1 diabetes.[ncbi.nlm.nih.gov] THE COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR D1 DOMAIN 1kac : KNOB DOMAIN FROM ADENOVIRUS SEROTYPE 12 IN COMPLEX WITH DOMAIN 1 OF ITS CELLULAR RECEPTOR CAR 1p69 : STRUCTURAL[en.wikipedia.org] […] mays) E. coli (Escherichia coli) filamentous fungi (Aspergillus nidulans) Firmicute bacteria (Streptococcus pneumoniae) fission yeast (Schizosaccharomyces pombe) fruit fly (Drosophila[genecards.org] [bsid125147] PodNet: protein-protein interactions in the podocyte PodNet: protein-protein interactions in the podocyte PodNet is a manually curated network of protein-protein[ncbi.nlm.nih.gov] Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein. J.[doi.org]

    Missing: Dromyosuppressin
  • Bombyx

    […] gene promoter (BmNPV-ie-1), and a synthetic promoter (3xP3) was carried out, the result indicated that the activity of P5 was weaker than that of anyone of them.[ncbi.nlm.nih.gov] receptors for sNPFs, but other sNPF receptors and their signaling mechanisms in B. mori remain unknown.[ncbi.nlm.nih.gov] More recently, the newly recognized B. mori receptor for Drosophila melanogaster sex peptide (DmSP) has been identified as a receptor for BmPTSP.[ncbi.nlm.nih.gov] In this study, we screened BmREEPa interacting protein through co-immunoprecipitation and finally identified a membrane protein, Bombyx mori patched domain containing protein[ncbi.nlm.nih.gov] […] findings indicate that some genes that cause the translucent phenotype in Bombyx, some HPS-associated genes in humans, and some genes that cause mutant eye color phenotypes in Drosophila[ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin
  • Inflammation

    Immunofluorescence was negative in 1 patient.[ncbi.nlm.nih.gov] Abstract The formyl peptide receptors (FPRs) are G protein coupled receptors that recognize a broad range of structurally distinct pathogen and danger-associated molecular[ncbi.nlm.nih.gov] Alain Van Dorsselaer, Jean-Marc Reichhart and Florian Veillard , The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila[doi.org] The rate of protein synthesis in vivo was measured by the incorporation of [3H]phenylalanine into liver proteins in a chronic (5 day) intra-abdominal abscess model.[doi.org] Author information 1 Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba X5000HUA, Argentina. [email protected][ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin
  • Laron Syndrome

    AIMS: To analyze the sleep macro- and microstructure in LS and to evaluate the influence of substitutive insulin-like growth factor 1 (IGF-1) therapy on it.[ncbi.nlm.nih.gov] Abstract The GH receptor (GHR) is a member of the cytokine receptor superfamily; GH binding protein is the solubilized extracellular domain of the GHR.[ncbi.nlm.nih.gov] Clancy DJ, Gems D, Harshman LG, et al, 2001 Extension of life span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292: 104-106. 14.[hormones.gr] To create a mammalian model for this disease, we generated mice bearing a disrupted GHR/binding protein (GHR/BP) gene through a homologous gene targeting approach.[ncbi.nlm.nih.gov] These effects are initiated by binding of growth hormone (GH) to growth hormone receptors (GHR) expressed in target cells.[ncbi.nlm.nih.gov]

    Missing: Dromyosuppressin