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8,531 Possible Causes for 1, E1A stimulated, cellular, genes, of, repressor

Did you mean: 1, E1A, stimulated, cellular, genes, of, repressor

  • Herpes Simplex Virus 1 Infection

    Herpes simplex virus type 1 (HSV-1) is the more common type of Herpes simplex virus.[] Thus, the balance between cellular repressors and virus-counteracting proteins determines whether or not a cell becomes productively infected.[] An integration analysis of circRNAs, genes, and miRNAs revealed the alleged involvement of dysregulated circRNAs in cellular responses to HSV-1 infection via the circRNA-miRNA-gene[] […] retention of ICP0 occurs in an ICP0 E3 ligase-dependent manner; and (iv) the ICP0 C terminus and late viral proteins cooperate in order to overcome nuclear retention and stimulate[] Autophagy stimulation was confirmed to significantly suppress HSV-1 infection in various cell types, without affecting cell viability.[] Therefore, IFI16 stability appears to be regulated by cellular factors in response to active HSV-1 infection rather than directly by ICP0.[]

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  • Keloid

    In addition, IWR-1 significantly increased the expression of MMPs, such as MMP-1, MMP-3 and MMP-13, along with the increase of gelatinase activity.[] MicroRNAs (miRNAs) have recently emerged as post-transcriptional gene repressors and participants in a diverse array of pathophysiological processes leading to skin disease[] Through this innovative in situ microdissection gene profiling approach, we provide better-defined gene signatures of distinct KD regions, thereby addressing KD heterogeneity[] The proportion and distribution of cellular and matrix collagen components were evaluated at the centre and periphery of each sample.[] Our results demonstrated that TMEM88 was lowly expressed in human keloid tissues and TGF-β1-stimulated KFs.[] INTRODUCTION: Successful wound healing represents the coordinated response of cellular, cytokine, and growth factor mechanisms involved in tissue recovery.[]

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  • Proteus

    They produced identical beta-lactamases, namely: TEM-1, VIM-1, and CMY-99.[] […] heat shock protein, flagellar capping protein, putative membrane protein and multidrug efflux protein were down-regulated, and four proteins including exported peptidase, repressor[] Our hypothesis is that new genes may have been acquired horizontally to exert the digestion tract infection and toxicity.[] Sciences, Yasuj, Iran. 2 Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, IR, Iran.[] While AKT signaling was suppressed with ARQ 092 treatment, cells retained their ability to respond to growth factor stimulation by increasing pAKT levels proportionally to[] Applying the FliC as an adjuvant resulted in the stimulation of mixed Th1- and Th2-immune responses against the truncated form of MrpH with a shift toward Th1.[]

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  • Helicobacter Pylori

    Abstract Human neutrophil peptide 1 (HNP1) is a small (3.44 kDa) cationic peptide that is a distinct member of the defensin family.[] Specifically, the HspR and HrcA repressors combine to control the transcription of target genes in a way that the HrcA regulon results embedded within the HspR regulon.[] This study aimed to investigate the relationship between single nucleotide polymorphisms (SNP) rs3804099 in the TLR2 gene and rs4986790 in the TLR4 gene with H. pylori infection[] However, the extent to which VacA-dependent mitochondrial perturbations affect overall cellular metabolism is poorly understood.[] A drug-induced lymphocyte stimulation test (DLST) showed positive reactions for both amoxicillin and metronidazole.[] Kotani S 1 , Miyaoka Y 2 , Fujiwara A 1 , Tsukano K 1 , Ogawa S 1 , Yamanouchi S 1 , Kusunoki R 1 , Fujishiro H 3 , Kohge N 1 , Ohnuma H 4 , Kinoshita Y 5 .[]

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  • Trichinella Spiralis

    The protective role of TSL-1 in T. spiralis-infected mice has been described.[] On comparing the capacity of TS to bind to its cognate mRNA, relative to its ability to inhibit its translation, the same enzyme preparation was active as translational repressor[] Gene expression for Th2 chemokine genes were highly enhanced by ES proteins in WT MEF cells, while this elevation was slightly reduced in MyD88/TIRAP(-/-) MEF cells, and quite[] Investigation of parasitism at the cellular and molecular levels has been challenging because of a shortage of tools for in vitro cultivation of T. spiralis.[] RESULTS: The results showed that gp45 inhibited both random and stimulated migrations, and reduced the response to f-MLP and PMA.[] This experimentation allowed then the selection of several adjuvants which efficacy will be further investigated by a challenge test and an analysis of the cellular populations[]

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  • Procainamide

    We report here that procainamide specifically inhibits the hemimethylase activity of DNA methyltransferase 1 (DNMT1), the mammalian enzyme thought to be responsible for maintaining[] ERbetacx, the carboxy terminal splicing variant of ERbeta, has been considered a dominant repressor of ERalpha function, because ERbetacx inhibits transcriptional activity[] […] p16 genes.[] Abstract Procainamide and related triethylamine-substituted 4-aminobenzamides, such as metoclopramide and declopramide, exert cellular effects potentially exploitable in oncology[] These effects of high current stimulation persisted after procainamide infusion.[] Aberrant promoter methylation of Wnt inhibitory factor-1 (WIF-1) is a fundamental mechanism of epigenetic silencing in human cancers.[]

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  • Fibrosarcoma

    Peroxiredoxin 1 (PRDX1) is considered to prevent tumors in many malignances.[] Internal tandem duplication of B-cell CLL/lymphoma 6 (BCL6)-interacting co-repressor (BCOR) exon 15 has recently been described in clear cell sarcoma of kidney, central nervous[] Gene expression was analyzed by RNA microarrays.[] However cellular fibroma may show a greater mitotic activity and therefore they should be referred as mitotically active cellular fibromas.[] Pharmacologic treatments will include chemotherapy agents, antimicrobial agents, as well as granulocyte colony-stimulating factor for immunosuppression.[] However, there was no change in the constitutive level of MMP-9 and TIMP-1 mRNAs and TIMP-1 protein in p-cymene-treated cells.[]

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  • Novobiocin

    RESULTS: Viability of HGF-1 was drastically reduced after 5 hour treatment with novobiocin in concentrations of 1 mM or higher.[] The transactivator was constructed by fusing the GyrB activator to the bacterial lambda repressor-binding domain.[] Abstract The antibiotic novobiocin is shown to alter the sedimentation properties of human cellular DNA in alkaline sucrose.[] In addition, novobiocin acted synergistically with butyrate but not with teleocidin in stimulating the procollagen production and the acetate uptake.[] Abstract Hypoxia-inducible factor 1α (HIF1α) is an important cellular survival protein under hypoxic conditions, regulating the cellular response to low oxygen tension via[] The processing and activation of caspases 7 and 8 and the subsequent cleavage of PARP by 6e suggest stimulation of the extrinsic apoptosis pathway.[]

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  • Hypoxia

    […] kinase; YC-1, 3-(5′-hydroxy-methyl-2′-furyl)-1-benzylindazole.[] OBJECTIVE: To examine the expression of hypoxia-inducible factor-1α (HIF-1α) and its related molecules (cellular repressor of E1A-stimulated genes [CREG], osteopontin [OPN[] BACKGROUND: Nonspecific siRNA expression limits its application in cancer gene therapy.[] Standard cancer lines mostly do not exhibit a cellular hypoxic microenvironment and there is a paucity of information on the efficacy of lead molecules in both cellular- and[] Both HIF‑1α and HIF‑2α may contribute to the regulation of cellular adaptation to hypoxia and resistance to cancer therapies.[] CONCLUSIONS: Acute NH subdues the exercise-associated rise in aldosteroe but stimulates cortisol, whereas prolonged exposure at HA reduces both resting aldosterone and cortisol[]

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  • Ceftriaxone

    Four men had diarrhoea classified as grade 1.[] GU110362 had A40D in the repressor of MtrR and L421P in PBP1. The strains did not have mutations of pilQ1 and pilQ2.[] genes.[] Recently, ceftriaxone a multi-potent β-lactam antibiotic able to overcome the blood-brain barrier, successfully eliminated the cellular toxic effects of misfolded mutated[] Ceftriaxone, one of the beta-lactam antibiotics, is a stimulator of EAAT2 expression with neuroprotective effects in both in vitro and in vivo models based in part on its[] We recently found that ceftriaxone, a β-lactam antibiotic able to overcome the blood-brain barrier, successfully eliminated the cellular toxic effects of misfolded proteins[]

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