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2,310 Possible Causes for 1, W2, and, basic, domains, human, leucine, protein,, zipper

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  • Phlebotomus Fever

    Symbol Name Standardized Value BZW1 basic leucine zipper and W2 domains 1 1.92155 DERA deoxyribose-phosphate aldolase (putative) 1.45836 CCDC130 coiled-coil domain containing[amp.pharm.mssm.edu] Fatigue, a slow heart rate and low blood pressure may persist from few days to several weeks but complete recovery is the rule. [1] Cause [ edit ] Three serotypes of Phlebovirus[en.wikipedia.org] The overall prevalence of Naples, Sicilian, and Karimabad virus antibodies among the human population was 17%, 25%, and 66%, respectively.[ncbi.nlm.nih.gov] Keywords Future Study Experimental Study Infectious Disease Human Body Basic Property These keywords were added by machine and not by the authors.[link.springer.com] 4634008 ) Morgan B.B....Alluisi E.A. 1973 17 Behavioral effects of infectious diseases: Phlebotomus fever in man. ( 4624616 ) Coates G.D....Alluisi E.A. 1972 18 Cross-reacting protein[malacards.org] No evidence of human infection with Salehabad virus was found.[ijph.tums.ac.ir] All infected subjects developed specific neutralizing antibodies with titers ranging from 1:40 to 1:2,560.[ncbi.nlm.nih.gov] ; ssRNA viruses; ssRNA negative-strand viruses; Bunyavirales; Phenuiviridae; Phlebovirus; Sandfly fever Naples phlebovirus GenBank X53794 Toscana virus sRNA for NS and N protein[genome.jp] Explore synonyms and related concepts fancy , baseball , clouds , twisty , push · Generate a list of words in some category large birds , soft cheese , green fruit · Answer basic[onelook.com]

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  • Parainfluenza Virus

    Additionally, 3 middle heptadic leucine residues at 271, 278, and 285 were replaced with alanine singly or in combination.[ncbi.nlm.nih.gov] […] therefore describe a 15-month-old white male who died suddenly and unexpectedly with clinical and pathological features of laryngotracheitis caused by culture-proven HPIV-1[ncbi.nlm.nih.gov] M protein (ML305A) has a VLP formation ability similar to that of wild-type M protein.[ncbi.nlm.nih.gov] IMPORTANCE We examined the importance of amino acids in the putative RNA-binding domain of hPIV2 NP for polymerase activity using minireplicons.[ncbi.nlm.nih.gov] In this review, we summarized the basic epidemiology and immunology of hPIVs and addressed the more recent data implicating the role of parainfluenza viruses in the exacerbation[ncbi.nlm.nih.gov] Uganda dying as a result of a human 'common cold' virus, a new study has identified two other respiratory viruses of human ... read more On the Brink of Eradication: Why Polio[sciencedaily.com] You are here › All Topics › Parainfluenza Virus 1, 2, 3, 4 Parainfluenza viruses (PIV) are the second most common cause of acute upper and lower respiratory tract infections[arupconsult.com] Crystal structure of an isoleucine-zipper trimer . Nature 371 , 80–83 (1994) 43.[nature.com] This suggests that the interaction between NP and the N-terminal domain plays a critical role in V inhibition of viral RNA synthesis by the N-terminal domain.[ncbi.nlm.nih.gov]

    Missing: W2 and
  • Quinacrine

    […] supernatant is unable to stimulate the scintillant. 22 HL-60 cells were suspended in fresh medium containing 14 C-thymidine (111 nCi/ml; for the DNA experiments) or 14 C-leucine[nature.com] (3-pyridyl)-1-butanone (NNK), which is known to be converted to active mutagen in the liver principally through CYP2E1.[ncbi.nlm.nih.gov] The drug was suggested to "covalently" modify the prion protein via an acridinyl exchange reaction.[ncbi.nlm.nih.gov] Zipper thought that a similar scarring effect could occur in the fallopian tubes if quinacrine was instilled into the uterine cavity.[ncbi.nlm.nih.gov] Abstract From the screening of a unique collection of 880 off-patent small organic molecules, we have found that quinacrine inhibits the interaction between a BH3 domain-derived[ncbi.nlm.nih.gov] The compounds were found to be highly potent against both blood-stage P.falciparum, chloroquine-sensitive 3D7 (IC50 17.0-39.0 nM) and chloroquine-resistant W2 and Dd2 strains[ncbi.nlm.nih.gov] In this paper, we report the synthesis and cell-based anti-prion activity of quinacrine analogs derived by replacing the basic alkyl side chain of quinacrine with 4-(4-methylpiperazin-I-yl[ncbi.nlm.nih.gov] Despite its development in the 1970s, the cellular and molecular events induced by quinacrine in the human fallopian tube have not been described.[ncbi.nlm.nih.gov] These were dialkylaminoalkyl and phenyl with basic groups on the phenyl ring.[ncbi.nlm.nih.gov]

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  • Rabies Virus

    KEYWORDS: Leucine zipper; RFFIT; Rabies; scFv; zipFv[ncbi.nlm.nih.gov] Here we report on a novel approach to utilize the binding of Intracellular Adhesion Molecule-1 (ICAM-1) to its binding partner, Lymphocyte Function-associated Antigen-1 (LFA[ncbi.nlm.nih.gov] The multifunctional RABV P-protein has essential roles in genome replication, and forms interactions with cellular STAT proteins that are thought to underlie viral antagonism[ncbi.nlm.nih.gov] The aa W265 within the epitope is on the flat surface of the domain, suggesting that it may be a critical amino acid for the functions of the P protein.[ncbi.nlm.nih.gov] RESULTS: Sequence analysis using basic local alignment search tool (BLAST) and multiple sequence alignment (MSA) and phylogenetic analysis showed similarity to previously[ncbi.nlm.nih.gov] Human globulin immune to rabies virus has also been used for treatment of one case of clinical human rabies; this use was based on the observation that antibodies to rabies[ncbi.nlm.nih.gov] […] red fluorescent protein (mRFP) as a transgene. rHEP5.0-ΔG-mRFP showed lower cytotoxicity than rHEP5.0-CVSG-mRFP, and within 16 days of infection we found no change in the basic[ncbi.nlm.nih.gov] KEYWORDS: Glycoprotein; Leucine zipper; Rabies virus; Single chain variable fragment; Virus-neutralization antibody; Zip variable fragment[ncbi.nlm.nih.gov] 10, 2018 ; 90 (15 Supplement) April 26, 2018 Alan Jackson , Wafa Kammouni , Heidi Wood , Paul Fernyhough First published April 9, 2018, Abstract Objective: To understand basic[n.neurology.org]

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  • Peptostreptococcus

    Leucine dissimilation using the Strickland reaction has been shown for P. anaerobius [32] .[academic.oup.com] Pyogenic Brain Abscess Caused by Peptostreptococcus in a Patient with HIV-1 Infection. Diseases 2017 , 5 , 26.[mdpi.com] One per cent SDS and M urea both extracted a major 78 kDa protein from all strains of P anaerobius.[ncbi.nlm.nih.gov] These two bacterial surface proteins interact with their respective immunoglobulin regions through a similar beta zipper interaction.[ncbi.nlm.nih.gov] […] naturally occurring VL fragments, and VL- and CL-related trypsin- and pepsin-derived peptides prepared from a kappa I light chain, localized the site of interaction to the VL domain[ncbi.nlm.nih.gov] Abstract Seven strains of anaerobic Gram-positive cocci isolated from human oral sites were subjected to a comprehensive range of phenotypic and genotypic tests. 16S rRNA[ncbi.nlm.nih.gov] In the present study, we investigated the response of human macrophages to stimulation with a cell wall preparation from P. micros.[ncbi.nlm.nih.gov] […] between the binding domain and kappa light chains (kappa-chains).[ncbi.nlm.nih.gov] ., which is found in human feces and vaginal discharge. This new species was established on the basis of the results of DNA-DNA hybridization among anaerobic cocci.[ncbi.nlm.nih.gov]

    Missing: W2 and basic
  • High Altitude Pulmonary Edema

    Compared to the plasma of the controls, the HAPE patients had significant increases in valine, lysine, leucine, isoleucine, glycerol phosphoryl choline, glycine, glutamine[ncbi.nlm.nih.gov] Jin T 1, 2, 3, 4 , Ren Y 4, 5 , Zhu X 1, 2, 3 , Li X 6 , Ouyang Y 4 , He X 1, 2, 3 , Zhang Z 1, 2, 3 , Zhang Y 1, 2, 3 , Kang L 1, 2, 3 , Yuan D 1, 2, 3 .[ncbi.nlm.nih.gov] OBJECTIVE: The purpose of this study was to test the hypothesis that polymorphisms in the endothelial PAS domain protein 1 (EPAS1) gene are associated with the susceptibility[ncbi.nlm.nih.gov] Portable chambers are near cylindrical in shape and are made out of medium to heavy weight, impermeable coated fabric with an air-proof zipper to accommodate a patient in[rakshapolycoats.com] Abstract As part of an emergency medical system protocol, national park service rangers certified at the level of an emergency medical technician-basic (EMT-B) are taught[ncbi.nlm.nih.gov] […] was found to have a high binding affinity with human beta(2) adrenergic receptor.[ncbi.nlm.nih.gov] This paper will review the basic pathophysiology, prevention, and treatment of the most serious of the high altitude clinical syndromes, high altitude pulmonary edema.[ncbi.nlm.nih.gov] Author information 1 Research Center for High Altitude Medical Science, Qinghai University School of Medicine, Xining 810001, China; Basic and Applied Key Laboratory for High[ncbi.nlm.nih.gov] Our findings suggested that sFlt-1 was a key factor that involved in HAPE pathogenesis and the sFlt-1/VEGF ratio could be used as a sensitive diagnostic marker for HAPE.[ncbi.nlm.nih.gov]

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  • Herpes Simplex Virus 1

    Extragenic suppressors of the UL34(Q163A) phenotype were isolated, and all of them carry a single mutation of arginine 229 to leucine in UL31.[ncbi.nlm.nih.gov] The Us11 protein of herpes simplex virus 1 (HSV-1) is an accessory factor with multiple functions.[ncbi.nlm.nih.gov] During viral infection, accumulation of viral proteins can cause stress in the endoplasmic reticulum (ER) and trigger the unfolded protein response (UPR) to restore ER homeostasis[ncbi.nlm.nih.gov] Here, we mapped the nuclear foci-targeting sequence to the central region containing the first leucine zipper (a.a.415-519), and found that the integrity of the whole region[ncbi.nlm.nih.gov] The functional regions of gD responsible for viral entry have been mapped to its extracellular domain, whereas the gD cytoplasmic domain plays no obvious role in viral entry[ncbi.nlm.nih.gov] College London, UK Correspondence to: K J Looker Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, St Mary’s Campus, Norfolk Place, London W2[sti.bmj.com] Author information 1 Department of Immunology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China [email protected] 2 Department of Microbiology[ncbi.nlm.nih.gov] Oral mucosa is one of the main target tissues of the human pathogen herpes simplex virus 1 (HSV-1).[ncbi.nlm.nih.gov] Jiangsu, China. 5 Microbiology and Immunology College of Medicine, National Cheng Kung University, Tainan, Taiwan, Republic of China. 6 Department of Immunology, School of Basic[ncbi.nlm.nih.gov]

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  • Osteosarcoma

    ZAK is a novel mixed lineage kinase-like protein that contains a leucine-zipper and a sterile-alpha motif as a protein-protein interaction domain, and it is located in the[ncbi.nlm.nih.gov] Peroxiredoxin 1 (PRDX1) is considered to prevent tumors in many malignances.[ncbi.nlm.nih.gov] Frizzled Related Protein (sFRP) 3, in osteosarcoma patients.[ncbi.nlm.nih.gov] Apatinib, a new potent oral small-molecule tyrosine kinase inhibitor targeting the intracellular domain of vascular endothelial growth factor receptor 2 (VEGFR-2), shows survival[ncbi.nlm.nih.gov] Osteosarcoma - Childhood and Adolescence: Introduction ON THIS PAGE : You will find some basic information about this disease and the parts of the body it may affect.[cancer.net] ATP Binding Cassette Transporter, Subfamily G, Member 2 Biomarkers, Tumor CD44 protein, human Hyaluronan Receptors IGF1R protein, human Neoplasm Proteins Receptors, Somatomedin[ncbi.nlm.nih.gov] Aims: Previous studies have found that long noncoding RNA taurine upregulated gene 1 (TUG1) can regulate osteosarcoma cells apoptosis and proliferation; the aim of this study[ncbi.nlm.nih.gov] The RING domain of TRIM21 was required for TRIM21 negative regulation of YWHAZ expression.[ncbi.nlm.nih.gov] BACKGROUND: Some studies have demonstrated that the collagen triple helix repeat containing 1 (CTHRC1) protein is abnormally expressed in multiple human solid tumors.[ncbi.nlm.nih.gov]

    Missing: W2 and
  • B-Cell Chronic Lymphocytic Leukemia

    […] of the HCDR2 as do rare HIV-1 gp41 and influenza hemagglutinin stem neutralizing antibodies, while IGHV1-69 gp41 antibodies induced by HIV-1 infection predominantly used leucine[ncbi.nlm.nih.gov] […] crucial for withstanding apoptosis, as shown by the use of phosphotyrosine phosphatase-I-I, a direct inhibitor of SHP-1, or SHP-1 knockdown.[ncbi.nlm.nih.gov] Different pathways were assessed for activation/expression of key signaling proteins. Data obtained were validated by Western blotting and confocal microscopy.[ncbi.nlm.nih.gov] […] reported greater levels of fatigue and worse functioning in physical domains.[ncbi.nlm.nih.gov] Netherlands. 7 Department of Epidemiology and Biostatistics, MRC-HPA Centre for Environment and Health, School of Public Health, Faculty of Medicine, Imperial College, London, W2[ncbi.nlm.nih.gov] ICOS enhances all the basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, the upregulation of molecules that mediate cell-cell interaction[ncbi.nlm.nih.gov] We have developed a protocol to expand Vδ1 and Vδ2 preferentially from human blood. We have characterized these subsets and their specificities for leukemic targets.[ncbi.nlm.nih.gov] […] several human, solid transplantable cancers.[ncbi.nlm.nih.gov] Additionally we determined the influence of lipopolysaccharide Escherichia coli - TLR4-ligand (LPS) and Staphylococcus aureus strain Cowan I - TLR2-ligand (SAC) on TIR-domain-containing[ncbi.nlm.nih.gov]

    Missing: and zipper
  • Helicobacter Pylori

    The cellular composition of GPCs included the combination of cytokeratin 18 (CK18) and E-cadherin (E-cad)-positive epithelial cells, MUC5AC-positive gastric cells, and leucine-rich[ncbi.nlm.nih.gov] Abstract Human neutrophil peptide 1 (HNP1) is a small (3.44 kDa) cationic peptide that is a distinct member of the defensin family.[ncbi.nlm.nih.gov] The high-resolution 3D models of the protein were created and were validated; indeed, the B-and T-cell restricted epitopes were mapped on the chimeric protein.[ncbi.nlm.nih.gov] METHODS: PCR products of 23S rRNA gene V domain of 74 H. pylori isolates; 34 resistant to clarithromycin (29 from a low-risk gastric cancer (GC) population: Tumaco-Colombia[ncbi.nlm.nih.gov] Electronic address: [email protected] 2 Department of Infectious Disease Epidemiology, Imperial College London, London W2 1PG, United Kingdom.[ncbi.nlm.nih.gov] Bibliografia Patient education: Helicobacter pylori infection and treatment (Beyond the Basics). UpToDate. Disponible a: Gisbert, J.P. et al.[medicaments.gencat.cat] The objective of this review is to discuss how H. pylori has co-evolved with humans, how H. pylori presence is associated with positive and negative effects in human health[ncbi.nlm.nih.gov] Kotani S 1 , Miyaoka Y 2 , Fujiwara A 1 , Tsukano K 1 , Ogawa S 1 , Yamanouchi S 1 , Kusunoki R 1 , Fujishiro H 3 , Kohge N 1 , Ohnuma H 4 , Kinoshita Y 5 .[ncbi.nlm.nih.gov] "Patient information: Helicobacter pylori infection and treatment (Beyond the Basics)." UpToDate. Updated: Sep 05, 2017. FDA.[medicinenet.com]

    Missing: and zipper