Create issue ticket

11,233 Possible Causes for 1,, H2AK, HISTONE

Show results in: 日本語

  • Herpes Simplex Virus 1 Infection

    Herpes simplex virus type 1 (HSV-1) is the more common type of Herpes simplex virus.[symptoma.com] […] pretreatment of cells with tranylcypromine (TCP), a drug widely used in the clinic to treat neurological disorders, restrains HSV-1 gene transcription by inhibiting the histone-modifying[ncbi.nlm.nih.gov] Histone marks around transcription start sites of HSV-1-induced and constitutively transcribed antisense transcripts are highly similar, indicating that the genetic loci are[ncbi.nlm.nih.gov]

    Missing: H2AK
  • Gaucher Disease Type 1

    According to similar studies, the incidence of Gaucher disease is about 1 in 50,000 live births in the general population, and 1 in 800 among Ashkenazi Jews.[symptoma.com] Finally, a trend on higher global histone H4 acetylation levels (p 0.054) was observed in the control group when compared to GD1 individuals.[ncbi.nlm.nih.gov] Author information 1 Springer, Private Bag 65901, Mairangi Bay, 0754, Auckland, New Zealand. [email protected][ncbi.nlm.nih.gov]

    Missing: H2AK
  • Spinocerebellar Ataxia Type 1

    […] type 1.[symptoma.com] In this study, we show that ATXN1 reduces histone acetylation, a post-translational modification of histones associated with enhanced transcription, and represses histone[ncbi.nlm.nih.gov] In contrast, AGG interruptions in (CGG)n tracts did not affect assembly by hypoacetylated histones.[ncbi.nlm.nih.gov]

    Missing: H2AK
  • Diabetes Mellitus Type 1

    Since the risk factors for type 1 diabetes have been studied thoroughly, this gave rise to the Diabetes Prevention Trial–Type 1 (DPT-1) and European Nicotinamide Diabetes[symptoma.com] In T1D, epigenetic phenomena, such as DNA methylation, histone modifications, and microRNA dysregulation, have been associated with altered gene expression.[ncbi.nlm.nih.gov] ., enteroviruses, retroviruses) Environmental toxins Various epigenetic modifications of gene expression (DNA methylation, histone modifications, and μ -RNA dysregulation)[unboundmedicine.com]

    Missing: H2AK
  • Corticotropin

    Author information 1 Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, AL7 3AX, UK.[ncbi.nlm.nih.gov] […] of H3K9 and other histone regions.[ncbi.nlm.nih.gov] N/A N/A [1] . JOURNAL Patent: DE 3731875-A 30-MAR-1989;, et al.[genwaybio.com]

    Missing: H2AK
  • Primary Hyperoxaluria

    PH1 is quite rare, with estimates placing its frequency worldwide between 1 in 100,000 and 1 in 1,000,000. In Europe, it affects an estimated 1 in 120,000 people.[counsyl.com] Brachydactyly mental retardation syndrome (BDMR) is an autosomal dominant disorder, caused by haploinsufficiency of histone deacetylase 4 (HDAC4), also on chromosome 2q37.[ncbi.nlm.nih.gov] Summary Epidemiology The prevalence of PH1 reported in Europe ranges from 1/333,000 - 1/1,000,000.[orpha.net]

    Missing: H2AK
  • Drug-induced Fever

    Body mass index (BMI), tympanic temperature, and plasma levels of leptin and cytokines (tumor necrosis factor-alpha (TNF-alpha), soluble TNF receptor 1 and 2 (sTNFR-1/2),[ncbi.nlm.nih.gov] Thus they are called anti-histone antibodies. Anti-histone antibodies may be seen in both systemic lupus erythematosus and drug-induced lupus.[clinicaladvisor.com] Drug Information and Pharmacotherapy DI-050 Drug induced fever caused by piperacillin-tazobactam in adults with cystic fibrosis S Khettar 1 , S Durupt 2 , J Pages 1 , R Nove[ejhp.bmj.com]

    Missing: H2AK
  • Neurofibroma

    Am J Med Genet A. 2003 May 15;119A(1):1-8.[ghr.nlm.nih.gov] Trichostatin A and other histone deacetylase inhibitors, as well as cantharidin and tamoxifen, were retrieved as putative therapeutic means to reverse the aberrant regulation[ncbi.nlm.nih.gov] Neurofibromatosis Type 1 Plexiform Neurofibroma Neurofibromatosis Type 1 Axillary Freckling Neurofibromatosis Type 1 Café au Lait Macule Neurofibromatosis Type 1 Café au Lait[epilepsy.com]

    Missing: H2AK
  • Multiple Endocrine Neoplasia Type 1

    IMPORTANCE: We believe this to be the first documented report of multiple endocrine neoplasia type-1 (MEN-1) in which the diagnosis was suspected based purely on cutaneous[ncbi.nlm.nih.gov] Menin, which acts as scaffold protein, may increase or decrease gene expression by epigenetic regulation of gene expression via histone methylation.[ncbi.nlm.nih.gov] […] activation of gene transcription as part of an MLL1 (mixed-lineage leukemia 1)/MLL2 (KMT2A/B)-containing protein complex which harbors methyltransferase activity for lysine 4 of histone[diagenode.com]

    Missing: H2AK
  • Malignant Peripheral Nerve Sheath Tumor

    INTRODUCTION: The prognosis of malignant peripheral nerve sheath tumor (MPNST) with neurofibromatosis type 1 (NF-1) is worse than that of a solitary MPNST, because of the[ncbi.nlm.nih.gov] […] encode subunits of polycomb repressive complex 2 (PRC2), have been identified in 70% to 92% of MPNSTs; PRC2 inactivation leads to loss of trimethylation of lysine 27 of histone[ncbi.nlm.nih.gov] Loss of expression of the trimethyl histone H3 at the Lys27 position (H3K27-me3) has recently been described in MPNSTs and may help distinguish this tumor from pathologic[ncbi.nlm.nih.gov]

    Missing: H2AK