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1,697 Possible Causes for 15,, SARS, coronovirus, nonstructural, protein

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  • Coronaviridae

    This condition is called SARS , which is the acronym for Severe Acute Respiratory Syndrome.[study.com] Their replicase genes encode an exceptionally large number of nonstructural protein domains which mediate the key functions required for genomic RNA synthesis (replication[ebi.ac.uk] Read more February 15, 2017 achengula Adenovirus , Arenaviridae , Arenavirus , Birnaviridae , Bovine herpesvirus , Bovine respiratory syncytial , Bunyaviridae , Calciviridae[achengula.com] Here we report the utility of the potent antiviral protein griffithsin (GRFT) in the prevention of SARS-CoV infection both in vitro and in vivo.[ncbi.nlm.nih.gov] Coronavirus replication-it.png 602 737; 408 KB Coronavirus replication.png 915 737; 474 KB Coronavirus virion.jpg 363 291; 36 KB Coronavirus.jpg 1,200 1,200; 1.05 MB Coronovirus-Kit.jpg[commons.wikimedia.org]

  • Middle East Respiratory Syndrome

    So far, it is known that the novel coronavirus responsible for MERS is the same as that which caused the SARS (Severe Acute Respiratory Syndrome) outbreak in 2002 and probably[well.org] The genome encodes both nonstructural and structural proteins.[mbio.asm.org] Received: 15 December 2018 / Revised: 8 January 2019 / Accepted: 10 January 2019 / Published: 14 January 2019 (This article belongs to the Special Issue MERS-CoV ) Middle[mdpi.com] It is different from SARS because MERS is caused by another subtype of the coronovirus.[medbroadcast.com] The time between hospitalization and either discharge or death is relatively short: a median of 7.0 and 9.0 days, respectively [ 15 ].[ajronline.org]

  • Tick-Borne Encephalitis Virus

    Here we present the nucleoside SAR exploration for tick-borne encephalitis virus (TBEV), a member of Flavivirus genus.[ncbi.nlm.nih.gov] OBJECTIVE: In the current study we explored the ability of TBEV nonstructural protein 1 (NS1) to induce oxidative stress and activate antioxidant defense via the nuclear factor[ncbi.nlm.nih.gov] Using nested RT-PCR, we were able to confirm the presence of TBEV in ticks for the first time after 15 years.[ncbi.nlm.nih.gov] We tried to identify host proteins interacting with the 3'-UTR of TBEV.[ncbi.nlm.nih.gov] RESULTS: We identified novel linear TBEV IgG epitopes in the E protein and in the nonstructural protein 5 (NS5).[ncbi.nlm.nih.gov]

    Missing: coronovirus
  • Severe Acute Respiratory Syndrome

    Abstract Accurate clinical diagnosis of severe acute respiratory syndrome (SARS) based on the current World Health Organization definition is difficult and at times impossible[ncbi.nlm.nih.gov] Here, we use transfection of plasmid constructs encoding full-length versions of the three transmembrane-containing nonstructural proteins (nsps) of the severe acute respiratory[ncbi.nlm.nih.gov] […] and who were admitted to the Queen Mary Hospital in Hong Kong between March 15 and April 15, 2003.[ncbi.nlm.nih.gov] The genome encodes for proteins that are homologous to known coronavirus proteins, such as the replicase proteins (ORFs 1a and 1b) and the four major structural proteins:[ncbi.nlm.nih.gov] A nonstructural SCoV nsp1 protein causes a severe translational shutoff by binding to the 40S ribosomal subunits.[ncbi.nlm.nih.gov]

    Missing: coronovirus
  • Influenza Virus

    Guided by the previously reported SAR data, a library of amino acid derivatives was synthesized.[ncbi.nlm.nih.gov] Nonstructural protein 1 (NS1) of influenza A virus regulates innate immune responses via various mechanisms.[ncbi.nlm.nih.gov] JY 1, 2 , Lee J 3 , Woo HJ 3 , Lee JS 4 , Wie SH 5 , Kim YK 6 , Jeong HW 7 , Kim SW 8 , Lee SH 9 , Park KH 10 , Kang SH 11 , Kee SY 12 , Kim TH 13 , Choo EJ 14 , Lee HS 15[ncbi.nlm.nih.gov] Here, we characterized the bat influenza A-like virus NS1 protein, a key virulence factor, and found unexpected functional divergence of this protein from counterparts in[ncbi.nlm.nih.gov] Epub 2011 Apr 15.[ncbi.nlm.nih.gov]

    Missing: coronovirus
  • Venezuelan Equine Encephalitis

    An Asn at the n-2 position relative to the Cys was also found in the coronaviral papain-like proteases/deubiquitinases (PLpro) of the SARS and MERS viruses, and in several[ncbi.nlm.nih.gov] We investigated the intracellular localization of the multifunctional nonstructural protein 2 (nsP2) in mammalian cells infected with Venezuelan equine encephalitis virus[ncbi.nlm.nih.gov] Antiviral Res. 2008 Dec;80(3):309-15. doi: 10.1016/j.antiviral.2008.07.002. Epub 2008 Aug 15.[ncbi.nlm.nih.gov] We aimed to identify and validate interactions of VEEV nonstructural protein 3 (nsP3) with host proteins and determine the consequences of these interactions to viral multiplication[ncbi.nlm.nih.gov] Epub 2012 Feb 15.[ncbi.nlm.nih.gov]

    Missing: coronovirus
  • Norwalk Virus

    Pertussis (Whooping Cough) Plague Pneumococcal Poliomyelitis Psittacosis Q Fever Rabies Rift Valley Fever Ringworm Rocky Mountain Spotted Fever Roundworm Rubella Salmonella SARS[lambtonhealth.on.ca] The nonstructural protein encoded in the N-terminal region of the first open reading frame (ORF1) of the Norwalk virus genome is analogous in gene order to proteins 2A and[ncbi.nlm.nih.gov] […] and 15 (83%) had or 4-fold increases in NV-specific salivary IgG when prechallenge and postchallenge saliva samples were compared.[ncbi.nlm.nih.gov] , and ORF3(51-212) interacted with the ORF2 protein, while an ORF3(1-107) protein did not.[ncbi.nlm.nih.gov] BACKGROUND: Our previous report that the Norwalk virus nonstructural protein p22 is an antagonist of the cellular secretory pathway suggests a new aspect of norovirus/host[ncbi.nlm.nih.gov]

    Missing: coronovirus
  • Chikungunya Virus

    It is also similar in all coronaviruses, which includes severe acute respiratory syndrome (SARS) and Middle East Respiratory Syndrome Coronavirus (MERS).[jhsph.edu] This is partly due to the lack of reliable systems for functional analysis of viral nonstructural polyproteins (ns-polyproteins) and nonstructural proteins (nsPs) in mosquito[ncbi.nlm.nih.gov] A case report is given of probable Chikungunya arthritis progressing to joint destruction before ultimately subsiding after 15 years leaving a sequela of destroyed metatarsal[ncbi.nlm.nih.gov] […] similar to the capsid protein of other alphaviruses.[ncbi.nlm.nih.gov] Am J Trop Med Hyg. 2016 Jul 6;95(1):180-1. doi: 10.4269/ajtmh.15-0547. Epub 2016 May 31.[ncbi.nlm.nih.gov]

    Missing: coronovirus
  • Ethylene Glycol

    Practice Division, University of Wisconsin-Madison, 777 Highland Avenue, Madison, WI 53705, USA. 2 Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong SAR[ncbi.nlm.nih.gov] ., garden and health service use Household hard surface cleaners (liquid) Lubricating oils Misc. tire repair materials Miscellaneous paint-related products Nonstructural caulking[scorecard.goodguide.com] FINDINGS: In comparison with unmodified PEG-(PCL) 8 micelles, PEG-(PCL-BTE) 8 micelles exhibited a 15-fold lower CMC, a 15-fold smaller size and a 50% higher drug loading[ncbi.nlm.nih.gov] […] of the proteins.[ncbi.nlm.nih.gov] Her admission data revealed a median pH of 7.31 (range 6.87-7.49), pCO(2): 4.2 kPa (1.2-6.7) (32 mmHg [9-50]), HCO-3: 15 mmol/L (4-26) (15 mEq/L [4-26]), base deficit (BD)[ncbi.nlm.nih.gov]

    Missing: coronovirus
  • Dengue Hemorrhagic Fever

    acute respiratory syndrome (SARS), and any other disease that can manifest in the acute phase as an undifferentiated febrile syndrome.[histopathology-india.net] We previously demonstrated that dengue virus (DENV) nonstructural 4B protein (NS4B) induced dengue hemorrhagic fever (DHF)-associated immunomediators in THP-1 monocytes.[ncbi.nlm.nih.gov] DHF, P 0.0034, Pc 0.044, OR 3.79] and HLA-DRB1*07/*15 genotype [DF vs.[ncbi.nlm.nih.gov] protein array and near-infrared (NIR) fluorescence detection.[ncbi.nlm.nih.gov] Formalin-fixed and frozen tissues were studied for evidence of virus infection using monoclonal antibodies against DENV structural and nonstructural antigens (E, NS1, and[ncbi.nlm.nih.gov]

    Missing: coronovirus