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8,708 Possible Causes for 2, 4,, phosphatase, protein, regulatory, subunit

Did you mean: 2, 4, phosphatase, proteus, regulatory, subunit

  • Influenza

    Single-dose treatments (5 to 40 mg/kg of body weight given intraperitoneally) of ferrets with 2'-deoxy-2'-fluoroguanosine or its prodrug, 2,6-diamino-purine-2'-fluororiboside[] The bound antibodies were detected with an alkaline phosphatase-conjugated antibody against mouse (Sigma).[] Influenza subunit vaccine - ten years experience. Europ J Clin Res 1992; 3: 117-38. [ Links ] 3. Nichol KL, Lind A, Margokis KL, et al .[] ., less than 4 days after illness onset).[] All problems (adverse events) related to a medicine or medical device used for treatment or in a procedure should be reported to the Medicines and Healthcare products Regulatory[] DOI: 10.1128/AAC.38.8.1864 ABSTRACT Single-dose treatments (5 to 40 mg/kg of body weight given intraperitoneally) of ferrets with 2'-deoxy-2'-fluoroguanosine or its prodrug[]

  • Lafora Disease

    Epilepsy, Progressive Myoclonic, 2A PME type 2 EPM2 Progressive myoclonic epilepsy type 2 Lafora Disease Epilepsy progressive myoclonic 2 Lafora body disorder Lafora Body[] Laforin contains a dual specificity phosphatase domain and a carbohydrate-binding module, and is a member of the recently described family of glucan phosphatases.[] Here we show that, in addition, laforin interacts with itself and with the glycogen targeting regulatory subunit R5 of protein phosphatase 1 (PP1).[] G279C in exon 4.[] Binary interactions i GO - Molecular function i identical protein binding Protein-protein interaction databases Structure i 3D structure databases Family & Domains i Phylogenomic[] […] and R6, which form complexes with the catalytic subunit of PP1.[]

  • Carney Complex

    Analysis of 11 kindreds and linkage to the short arm of chromosome 2.[] PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. ‏[] To accomplish this goal, we introduced null alleles of the PKA catalytic subunits Prkaca (Ca) or Prkacb (Cb) into the Prkar1a-cardiac knockout (R1a-CKO) or limited Schwann[] Bandettini WP 1 , Karageorgiadis AS 2 , Sinaii N 3 , Rosing DR 1 , Sachdev V 1 , Schernthaner-Reiter MH 4 , Gourgari E 2 , Papadakis GZ 5 , Keil MF 4 , Lyssikatos C 4 , Carney[] AMP-Dependent Protein Kinase RIalpha Subunit PRKAR1A protein, human RNA, Messenger RNA, Small Interfering SMAD3 protein, human Smad3 Protein Transforming Growth Factor beta[] BACKGROUND: Carney complex (CNC) is an autosomal dominant multiple neoplasia, caused mostly by inactivating mutations of the regulatory subunit 1A of the protein kinase A[]

  • Spinocerebellar Ataxia Type 12

    Postepy Biochem. 2005;51(2):215-22. Chai Y, Wu L, Griffin JD, Paulson HL.[] This hypothesis would predict that the mutation changes the regulation of protein phosphatase 2A, with implications for the phosphoproteome.[] […] action tremor, mild cerebellar dysfunction, and hyperreflexia, genetic testing revealed abnormal CAG repeat length in the brain-specific protein phosphatase 2, regulatory subunit[] Test Cost : 3000.00 AED Reporting Time: 4 Week Sample Type: EDTA blood or DNA Spinocerebellar ataxia type 12 autosomal dominant (PPP2R2B) Test Description : Spinocerebellar[] […] spots, which were confirmed as nine proteins by LC-MS/MS.[] SCA12 is linked to a CAG repeat expansion mutation in exon 7 of PPP2R2B, a gene that encodes Bβ, a regulatory subunit of protein phosphatase 2A (PP2A).[]

  • Osteoporosis

    Huang WS 1 , Hsu JW 1, 2 , Huang KL 1, 2 , Bai YM 1, 2 , Su TP 1, 2, 3 , Li CT 1, 2 , Lin WC 1, 2 , Chen TJ 4, 5 , Tsai SJ 1, 2 , Liou YJ 1, 2 , Chen MH 1, 2 .[] Biochemical markers, especially intact parathyroid hormone and bone-specific alkaline phosphatase, also may be helpful.[] Overexpression of microRNA‑148a significantly reduced estrogen receptor a (ERα) protein expression and suppressed phosphoinositide‑3‑kinase regulatory subunit 1 (PI3K) and[] Figures and Tables - Analysis 4.2 Comparison 4 Musculoskeletal pain, Outcome 2 Lower limb pain 4 years.[] A similar increase in risk was observed for animal protein, but no association was found for consumption of vegetable protein.[] Immune and bone cells are located in the bone marrow and share numerous regulatory molecules, signaling molecules, and transcription factors.[]

  • Episodic Ataxia

    […] in an EA–2 clinical phenotype.[] Cell specific modulators, such as kinases and phosphatases, of the calcium channel could also contribute to the restricted expression of this genetic mutation.[] We propose that EA1 mutations affect the rate of N-type inactivation either by reduced subunit surface expression, giving rise to a reduced number of Kv1.1 subunits in heterotetramer[] (4-AP; 5 mg tid).[] I262T appears to be the first EA1 mutation directly associated with impaired protein stability.[] These studies provide the first evidence that mutations associated with human genetic disorders can affect cis-regulatory elements to alter RNA editing.[]

  • Primary Pigmented Nodular Adrenocortical Disease

    Acronym PPNAD2 Synonyms Adrenal Cushing syndrome due to PPNAD2 Primary pigmented micronodular adrenocortical disease 2 Primary pigmented nodular adrenocortical disease-2 Keywords[] PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. ‎[] Genetically lean mice result from targeted disruption of the RIIb subunit of protein kinase A . Nature 382 , 622–626 (1996). 20. Amieux, P.S. et al .[] All the adrenal glands contained multiple small, black or brown cortical nodules, up to 4 mm in diameter.[] […] of Carney complex, a familial lentiginosis-multiple endocrine neoplasia syndrome frequently caused by mutations in PRKAR1A, which encodes the 1alpha regulatory subunit of protein[] An analysis of the patient and his mother's genomic DNA identified a novel mutation in the type Iα regulatory subunit of protein kinase A (PRKAR1A) gene; p.E17X (c.49G T).[]

  • Hereditary Hypophosphatemic Rickets with Hypercalciuria

    Term Browser Genes (2) Models (2) Disease References using Mouse Models (2)[] ; the father, high alkaline phosphatases.[] Nishida Atypical bartter syndrome with sensorineural deafness with G47R mutation of the beta-subunit for ClC-ka and ClC-kb chloride channels, barttin [29.] A.[] […] activities and osteocalcin syntheses by a physiological concentration of 1,25(OH)(2)D(3) were not stimulated by the increased medium phosphate concentrations from 0.5 to 4[] Pages: 1 NPT2C Polyclonal Antibody Gene Names: NPT2C ; SLC34A3; HHRH; NPTIIc Other Names: Sodium-dependent phosphate transport protein 2C; Sodium-phosphate transport protein[] Intracellular regulatory roles for the inorganic phosphate anion involve such diverse functions as control of aerobic metabolism, control of the O 2 dissociation curve of[]

  • Interleukin-2

    […] low dose rIL-2.[] Increased phosphorylation of VE-cadherin was also accompanied by a reduction of Src homology 2 domain-containing protein-tyrosine phosphatase 2, known to maintain vascular[] Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Ralpha), beta (IL-2Rbeta), and common gamma chain (gammac) receptor subunits[] The serum levels of IL-4 and -10 were significantly raised in severe dengue cases as compared to nonsevere dengue cases.[] Search results for IL2 Gene & protein summaries for IL2 Gene summary for IL2 Gene & protein summary for IL2 ORGANISMS human Homo sapiens human Homo sapiens house mouse Mus[] This synergistic effect was stopped by CD4 CD25 regulatory T cells (Treg), which depleted IL-2 in a cell number-dependent manner.[]

  • Cantharidin

    However, cantharidin also induced apoptosis and G(2)/M phase arrest in HT 29 cells, but did not induce COX 2 over-expression.[] Its cytotoxicity is believed to be mediated by the inhibition of serine/threonine protein phosphatase 2A.[] […] α (IKKα) and NF‑κB inhibitor α (IκBα) in cells, and an increased NF‑κB p65 subunit level in the nucleus.[] The results indicated that 8 genes were upregulated 4-fold, 29 genes were upregulated 3-4-fold and 156 genes were upregulated 2-3-fold.[] […] drug effects T-Lymphocytes, Regulatory/immunology T-Lymphocytes, Regulatory/radiation effects Substances CTLA-4 Antigen Ctla4 protein, mouse Cantharidin[] […] cell-permeable, potent and specific inhibitor of serine/threonine protein phosphatases 1 2 and 2A 3 by competitively docking in the ligand binding site at the beta catalytic subunit[]