Create issue ticket

8,708 Possible Causes for 2, 4,, phosphatase, protein, regulatory, subunit

Did you mean: 2, 4, phosphatase, proteus, regulatory, subunit

  • Influenza

    Single-dose treatments (5 to 40 mg/kg of body weight given intraperitoneally) of ferrets with 2'-deoxy-2'-fluoroguanosine or its prodrug, 2,6-diamino-purine-2'-fluororiboside[ncbi.nlm.nih.gov] The bound antibodies were detected with an alkaline phosphatase-conjugated antibody against mouse (Sigma).[dx.doi.org] Influenza subunit vaccine - ten years experience. Europ J Clin Res 1992; 3: 117-38. [ Links ] 3. Nichol KL, Lind A, Margokis KL, et al .[scielo.org.ar] ., less than 4 days after illness onset).[web.archive.org] All problems (adverse events) related to a medicine or medical device used for treatment or in a procedure should be reported to the Medicines and Healthcare products Regulatory[guidance.nice.org.uk] DOI: 10.1128/AAC.38.8.1864 ABSTRACT Single-dose treatments (5 to 40 mg/kg of body weight given intraperitoneally) of ferrets with 2'-deoxy-2'-fluoroguanosine or its prodrug[doi.org]

  • Lafora Disease

    Epilepsy, Progressive Myoclonic, 2A PME type 2 EPM2 Progressive myoclonic epilepsy type 2 Lafora Disease Epilepsy progressive myoclonic 2 Lafora body disorder Lafora Body[wikidata.org] Laforin contains a dual specificity phosphatase domain and a carbohydrate-binding module, and is a member of the recently described family of glucan phosphatases.[ncbi.nlm.nih.gov] Here we show that, in addition, laforin interacts with itself and with the glycogen targeting regulatory subunit R5 of protein phosphatase 1 (PP1).[ncbi.nlm.nih.gov] G279C in exon 4.[ncbi.nlm.nih.gov] Binary interactions i GO - Molecular function i identical protein binding Protein-protein interaction databases Structure i 3D structure databases Family & Domains i Phylogenomic[expasy.org] […] and R6, which form complexes with the catalytic subunit of PP1.[hmg.oxfordjournals.org]

  • Carney Complex

    Analysis of 11 kindreds and linkage to the short arm of chromosome 2.[ncbi.nlm.nih.gov] PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. ‏[books.google.com] To accomplish this goal, we introduced null alleles of the PKA catalytic subunits Prkaca (Ca) or Prkacb (Cb) into the Prkar1a-cardiac knockout (R1a-CKO) or limited Schwann[ncbi.nlm.nih.gov] Bandettini WP 1 , Karageorgiadis AS 2 , Sinaii N 3 , Rosing DR 1 , Sachdev V 1 , Schernthaner-Reiter MH 4 , Gourgari E 2 , Papadakis GZ 5 , Keil MF 4 , Lyssikatos C 4 , Carney[ncbi.nlm.nih.gov] AMP-Dependent Protein Kinase RIalpha Subunit PRKAR1A protein, human RNA, Messenger RNA, Small Interfering SMAD3 protein, human Smad3 Protein Transforming Growth Factor beta[ncbi.nlm.nih.gov] BACKGROUND: Carney complex (CNC) is an autosomal dominant multiple neoplasia, caused mostly by inactivating mutations of the regulatory subunit 1A of the protein kinase A[ncbi.nlm.nih.gov]

  • Spinocerebellar Ataxia Type 12

    Postepy Biochem. 2005;51(2):215-22. Chai Y, Wu L, Griffin JD, Paulson HL.[bvs.sld.cu] This hypothesis would predict that the mutation changes the regulation of protein phosphatase 2A, with implications for the phosphoproteome.[ncbi.nlm.nih.gov] […] action tremor, mild cerebellar dysfunction, and hyperreflexia, genetic testing revealed abnormal CAG repeat length in the brain-specific protein phosphatase 2, regulatory subunit[ncbi.nlm.nih.gov] Test Cost : 3000.00 AED Reporting Time: 4 Week Sample Type: EDTA blood or DNA Spinocerebellar ataxia type 12 autosomal dominant (PPP2R2B) Test Description : Spinocerebellar[dnalabsuae.com] […] spots, which were confirmed as nine proteins by LC-MS/MS.[ncbi.nlm.nih.gov] SCA12 is linked to a CAG repeat expansion mutation in exon 7 of PPP2R2B, a gene that encodes Bβ, a regulatory subunit of protein phosphatase 2A (PP2A).[ncbi.nlm.nih.gov]

  • Osteoporosis

    Huang WS 1 , Hsu JW 1, 2 , Huang KL 1, 2 , Bai YM 1, 2 , Su TP 1, 2, 3 , Li CT 1, 2 , Lin WC 1, 2 , Chen TJ 4, 5 , Tsai SJ 1, 2 , Liou YJ 1, 2 , Chen MH 1, 2 .[ncbi.nlm.nih.gov] Biochemical markers, especially intact parathyroid hormone and bone-specific alkaline phosphatase, also may be helpful.[ncbi.nlm.nih.gov] Overexpression of microRNA‑148a significantly reduced estrogen receptor a (ERα) protein expression and suppressed phosphoinositide‑3‑kinase regulatory subunit 1 (PI3K) and[ncbi.nlm.nih.gov] Figures and Tables - Analysis 4.2 Comparison 4 Musculoskeletal pain, Outcome 2 Lower limb pain 4 years.[doi.org] A similar increase in risk was observed for animal protein, but no association was found for consumption of vegetable protein.[doi.org] Immune and bone cells are located in the bone marrow and share numerous regulatory molecules, signaling molecules, and transcription factors.[ncbi.nlm.nih.gov]

  • Episodic Ataxia

    […] in an EA–2 clinical phenotype.[doi.org] Cell specific modulators, such as kinases and phosphatases, of the calcium channel could also contribute to the restricted expression of this genetic mutation.[jnnp.bmj.com] We propose that EA1 mutations affect the rate of N-type inactivation either by reduced subunit surface expression, giving rise to a reduced number of Kv1.1 subunits in heterotetramer[ncbi.nlm.nih.gov] (4-AP; 5 mg tid).[ncbi.nlm.nih.gov] I262T appears to be the first EA1 mutation directly associated with impaired protein stability.[ncbi.nlm.nih.gov] These studies provide the first evidence that mutations associated with human genetic disorders can affect cis-regulatory elements to alter RNA editing.[ncbi.nlm.nih.gov]

  • Primary Pigmented Nodular Adrenocortical Disease

    Acronym PPNAD2 Synonyms Adrenal Cushing syndrome due to PPNAD2 Primary pigmented micronodular adrenocortical disease 2 Primary pigmented nodular adrenocortical disease-2 Keywords[uniprot.org] PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. ‎[books.google.de] Genetically lean mice result from targeted disruption of the RIIb subunit of protein kinase A . Nature 382 , 622–626 (1996). 20. Amieux, P.S. et al .[doi.org] All the adrenal glands contained multiple small, black or brown cortical nodules, up to 4 mm in diameter.[ncbi.nlm.nih.gov] […] of Carney complex, a familial lentiginosis-multiple endocrine neoplasia syndrome frequently caused by mutations in PRKAR1A, which encodes the 1alpha regulatory subunit of protein[ncbi.nlm.nih.gov] An analysis of the patient and his mother's genomic DNA identified a novel mutation in the type Iα regulatory subunit of protein kinase A (PRKAR1A) gene; p.E17X (c.49G T).[ncbi.nlm.nih.gov]

  • Hereditary Hypophosphatemic Rickets with Hypercalciuria

    Term Browser Genes (2) Models (2) Disease References using Mouse Models (2)[informatics.jax.org] ; the father, high alkaline phosphatases.[ncbi.nlm.nih.gov] Nishida Atypical bartter syndrome with sensorineural deafness with G47R mutation of the beta-subunit for ClC-ka and ClC-kb chloride channels, barttin [29.] A.[apcontinuada.com] […] activities and osteocalcin syntheses by a physiological concentration of 1,25(OH)(2)D(3) were not stimulated by the increased medium phosphate concentrations from 0.5 to 4[ncbi.nlm.nih.gov] Pages: 1 NPT2C Polyclonal Antibody Gene Names: NPT2C ; SLC34A3; HHRH; NPTIIc Other Names: Sodium-dependent phosphate transport protein 2C; Sodium-phosphate transport protein[mybiosource.com] Intracellular regulatory roles for the inorganic phosphate anion involve such diverse functions as control of aerobic metabolism, control of the O 2 dissociation curve of[ommbid.mhmedical.com]

  • Interleukin-2

    […] low dose rIL-2.[doi.org] Increased phosphorylation of VE-cadherin was also accompanied by a reduction of Src homology 2 domain-containing protein-tyrosine phosphatase 2, known to maintain vascular[ncbi.nlm.nih.gov] Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Ralpha), beta (IL-2Rbeta), and common gamma chain (gammac) receptor subunits[rcsb.org] The serum levels of IL-4 and -10 were significantly raised in severe dengue cases as compared to nonsevere dengue cases.[ncbi.nlm.nih.gov] Search results for IL2 Gene & protein summaries for IL2 Gene summary for IL2 Gene & protein summary for IL2 ORGANISMS human Homo sapiens human Homo sapiens house mouse Mus[ebi.ac.uk] This synergistic effect was stopped by CD4 CD25 regulatory T cells (Treg), which depleted IL-2 in a cell number-dependent manner.[ncbi.nlm.nih.gov]

  • Cantharidin

    However, cantharidin also induced apoptosis and G(2)/M phase arrest in HT 29 cells, but did not induce COX 2 over-expression.[ncbi.nlm.nih.gov] Its cytotoxicity is believed to be mediated by the inhibition of serine/threonine protein phosphatase 2A.[ncbi.nlm.nih.gov] […] α (IKKα) and NF‑κB inhibitor α (IκBα) in cells, and an increased NF‑κB p65 subunit level in the nucleus.[ncbi.nlm.nih.gov] The results indicated that 8 genes were upregulated 4-fold, 29 genes were upregulated 3-4-fold and 156 genes were upregulated 2-3-fold.[ncbi.nlm.nih.gov] […] drug effects T-Lymphocytes, Regulatory/immunology T-Lymphocytes, Regulatory/radiation effects Substances CTLA-4 Antigen Ctla4 protein, mouse Cantharidin[ncbi.nlm.nih.gov] […] cell-permeable, potent and specific inhibitor of serine/threonine protein phosphatases 1 2 and 2A 3 by competitively docking in the ligand binding site at the beta catalytic subunit[alomone.com]