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1,065 Possible Causes for 2, Aldehyde, DEHYDROGENASE

  • Aldehyde

    Some aldehydes are substrates for aldehyde dehydrogenase enzymes which metabolize aldehydes in the body.[] Furthermore, an ALDH2 inactivating mutation (termed ALDH2*2) is the most common single point mutation in humans, and epidemiological studies suggest a correlation between[] These enzymes include alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which play a significant role in the metabolism of many biological substances and exist[]

  • Sjogren-Larsson Syndrome

    Toxicity of long-chain aldehydes for FALDH-deficient cells decreased almost to the level of unaffected keratinocytes.[] Subject has active ichthyosis that is Grade 2 or higher on the VIIS scaling severity score.[] Studies of mutations in SLS should prove useful for understanding structure-function correlations in FALDH and other aldehyde dehydrogenase proteins.[]

  • Xanthinuria

    J Urol. 1988 Feb;139(2):338-9. Author information 1 Department of Surgery, Al Qassimi Hospital, Sharjah, United Arab Emirates.[] […] lack aldehyde oxidase activity.[] The duodenal mucosa from the subject had no xanthine dehydrogenase protein while the mRNA level was not reduced.[]

  • Disulfiram

    The estimated fold increases in cell-associated unspliced HIV RNA from baseline were 1·7 (95% CI 1·3-2·2; p INTERPRETATION: Short-term administration of disulfiram resulted[] Disulfiram (DSF), an inhibitor of aldehyde dehydrogenase, is currently in clinical use for treating alcoholism.[] Thomas, 1970Vol. 2, Pg. 73, 1970. man TDLo oral 857mg/kg (857mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: COMA Human Toxicology.[]

  • Influenza

    Single-dose treatments (5 to 40 mg/kg of body weight given intraperitoneally) of ferrets with 2'-deoxy-2'-fluoroguanosine or its prodrug, 2,6-diamino-purine-2'-fluororiboside[] Infectivity of the virion is easily inactivated by all alcoholic disinfectants, chlorine, aldehydes and temperature above 70 C. Sources[] […] lymphopenia, elevated amino-transaminases, thrombocytopenia, prolonged prothrombin time and activated partial thromboplastin time, increased D-Dimer, increased serum lactate dehydrogenase[]

  • 2-Methylbutyryl-CoA Dehydrogenase Deficiency

    […] dehydrogenase (NAD ) • Deficiency of aldehyde oxidase • Deficiency of aldehyde reductase • Deficiency of aldehyde-lyase • Deficiency of aldonolactonase • Deficiency of aldose[] Consequently, a urine organic acid profile may reveal increased amounts of 2-methylbutyrylglycine and possibly 2-methylbutyrylcarnitine.[] […] dehydrogenase Deficiency of aldehyde oxidase Deficiency of aldehyde reductase Deficiency of aldehyde-lyase Deficiency of aldonolactonase Deficiency of aldose 1-epimerase[]

  • Xanthinuria Type 1

    With high fluid intake and low purine diet, no significant increase in calculi has been observed in this patient for 2 years. [Indexed for MEDLINE] Free full text[] […] allopurinol to oxipurinol during an allopurinol loading test for determining the type of classical xanthinuria revealed that the patients had classical type 1 xanthinuria, because aldehyde[] Proteolytic conversion of xanthine dehydrogenase from the NAD-dependent type to the O2-dependent type.[]

  • 2-Hydroxyglutaric Aciduria

    Fatty aldehyde dehydrogenase is necessary for the oxidation of long-chain aldehydes and alcohols to fatty acids.[] The major types of this disorder are called D- 2-hydroxyglutaric aciduria (D-2-HGA), L- 2-hydroxyglutaric aciduria (L-2-HGA), and combined D,L- 2-hydroxyglutaric aciduria[] […] mutations in the d-2-hydroxyglutarate dehydrogenase gene cause d-2-hydroxyglutaric aciduria.[]

  • Xanthinuria Type 2

    Xanthinuria type 2 type II xanthinuria, a type of classical xanthinuria , is a rare autosomal recessive disorder of purine Metabolism characterized by the deficiency of both[] […] of xanthine dehydrogenase and aldehyde oxidase.[] Last updated: 2/29/2012 This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person.[]

  • Disulfiram-like Reaction

    The protein expression of aldehyde dehydrogenase 2 was not affected at all.[] .), a semisynthetic, parenteral cephalosporin undergoing clinical trials in the United States, was administered in single 1-, 2-, and 3-g doses to 12 healthy volunteers.[] Drug-Food Interactions Section 2: Drug Classes 1. Antiretrovirals 2. Non-HIV Antivirals 3. Rifamycins and other Anti-Tubercular Agents 4.[]

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