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4,591 Possible Causes for 2,, II,, Mb2, class, histocompatibility, locus, mouse, protein

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  • Campylobacter Jejuni

    II/6, pp. 121-138). Washington, USA: ASM International.[orbit.dtu.dk] […] in the mouse intestine.[ncbi.nlm.nih.gov] OBJECTIVE: The simplest α 1,2 -fucosylated HMOS structure, 2'-fucosyllactose (2'-FL), can be predominant at 5 g/L milk.[ncbi.nlm.nih.gov] The host cell binding domain of FliD was mapped to the central region of the protein.[ncbi.nlm.nih.gov] Whole proteome of C. jejuni was investigated for varied properties like antigenicity, allergenicity, major histocompatibility class (MHC)-peptide interaction, immune cell[ncbi.nlm.nih.gov] Chicken and human isolates generally had similar distributions of the putative virulence genes and LOS locus classes studied.[ncbi.nlm.nih.gov] CPS genotyping was performed using a newly established multiplex polymerase chain reaction (PCR) method and lipooligosaccharide (LOS) locus classes (A-E) were characterized[ncbi.nlm.nih.gov] KEYWORDS: CRISPR/Cas; Campylobacter jejuni; genome-modified mouse[ncbi.nlm.nih.gov]

    Missing: Mb2
  • Clonorchis Sinensis

    Eligible participants were randomly assigned to one of four groups: (i) a single dose of 400 mg tribendimidine, (ii) 200 mg tribendimidine twice daily, (iii) 75 mg/kg praziquantel[ncbi.nlm.nih.gov] […] peroxidation, enzymes involved in lipid peroxidation, and mutagenic DNA adducts in the livers of mice infected with C. sinensis, as well as proinflammatory cytokines in infected mouse[ncbi.nlm.nih.gov] The CCC, PXSC, and CG motives characteristic to extracellular loop 2 (EC2) region of TSP-2 were well conserved.[ncbi.nlm.nih.gov] We identified antigenic proteins from adult C. sinensis liver flukes using immunoproteomic analysis.[ncbi.nlm.nih.gov] RESULTS: Both proteins induced a dose-dependent upregulation in major histocompatibility complex and co-stimulatory molecule expression and increased secretion of pro-inflammatory[ncbi.nlm.nih.gov] One independent monomeric locus and two independent polyubiquitin loci were firstly identified from the genome of carcinogenic liver fluke, Clonorchis sinensis (C. sinensis[ncbi.nlm.nih.gov] Definition noun A liver fluke species belonging to the family Opisthorchiidae of the Class Trematoda , and endemic in Japan, Taiwan, China, and Southeast Asia Supplement Clonorchis[biology-online.org] In addition, the structure modeling had also shown other functional domains: GTP/Mg(2 ) binding sites, switch I region, and switch II region.[ncbi.nlm.nih.gov]

    Missing: Mb2
  • Idiopathic Pulmonary Fibrosis

    We examined human leukocyte antigen (HLA) alleles in both families, including antigens Class I (locus A, B, and C) and Class II (locus DR).[ncbi.nlm.nih.gov] Penn researchers develop first mouse model of idiopathic pulmonary fibrosis The biggest hurdle to finding effective therapies for idiopathic pulmonary fibrosis (IPF) – a life-threatening[news-medical.net] Objective: To determine the effect of recombinant human pentraxin 2 vs placebo on change from baseline to week 28 in mean forced vital capacity (FVC) percentage of predicted[ncbi.nlm.nih.gov] […] misfolded proteins when they accumulate.[ncbi.nlm.nih.gov] The median survival was 43.7 months (23.6-71.7) with a majority (45%) of patients in the group II of the GAP index.[ncbi.nlm.nih.gov] Using a humanized severe combined immunodeficient mouse, we then demonstrated increased fibrosis in murine lungs receiving human lung fibroblasts from rapid progressors compared[stm.sciencemag.org] The phenotypic characteristics of all patients stratified according to slow 4MGS ( RESULTS: Intra-class correlation coefficients for inter-observer and test-retest reliability[ncbi.nlm.nih.gov] KEYWORDS: Angiotensin II; Caveolin‑1; Endothelin‑1; Growth factor; Inflammation; Melatonin; Pulmonary fibrosis; Wnt/β‑catenin[ncbi.nlm.nih.gov]

    Missing: Mb2
  • Brucella Abortus

    B. abortus was not only able to reduce the expression of mature MHC-II, but it also inhibited the expression of invariant chain (Ii)-associated immature MHC-II molecules.[ncbi.nlm.nih.gov] Based on this observation, we explored the interaction of mouse neutrophils with B. abortus In contrast to human, dog, and bovine neutrophils, naive mouse neutrophils fail[ncbi.nlm.nih.gov] CCL20 expression was mainly mediated by JNK1/2 and NF-kB in both Calu-6 and THP-1 cells.[ncbi.nlm.nih.gov] These results suggest that the two recombinant proteins of B. abortus may be potential LPS-free proteins for diagnosis.[ncbi.nlm.nih.gov] Its proteolytic activity enhances the quantity and quality of peptides to be presented by major histocompatibility complex class I (MHC-I) molecules to CD8 T cells.[ncbi.nlm.nih.gov] Genotyping was performed using multi-locus variable-number tandem-repeat analysis (MLVA).[ncbi.nlm.nih.gov] However, DHEA treatment increases the expression of costimulatory molecules (CD40, CD86), the adhesion molecule CD54, and major histocompatibility complex class I (MHC-I)[ncbi.nlm.nih.gov] Moreover, mutants were classified into class I, class II and class III as higher, similar, and lower internalization, respectively, into HeLa cells.[ncbi.nlm.nih.gov]

    Missing: Mb2
  • Fibrosarcoma

    Abstract Platinum-based antitumor drugs such as 1,1,2,2-cis-diamminedichloroplatinum(II) (cisplatin), carboplatin, and oxaliplatin are currently used to treat nearly 50% of[ncbi.nlm.nih.gov] The inflammatory-to-normal muscle uptake ratio was also calculated in an inflammation mouse model. A biodistribution study was performed to calculate %ID/g.[ncbi.nlm.nih.gov] MMP-2 expression, as determined by gelatin zymography.[ncbi.nlm.nih.gov] Major histocompatibility complex class II B7-1 tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice. J. Exp. Med. 181: 619-629, 1995.[atcc.org] Fluorescence in situ hybridization showed a translocation involving the EWSR1 gene locus in case 2.[ncbi.nlm.nih.gov] Abstract Injectable hydrogels are an important class of biomaterials, and they have been widely used for controlled drug release.[ncbi.nlm.nih.gov] To explore the effect of iron withdrawal on cancer cell growth, mouse and human mammary carcinoma cells (4T1 and MDA-MB-468, respectively) and mouse and human fibrosarcoma[ncbi.nlm.nih.gov] Field H-l Field S-3 Field T-2 gland haploid host IBM punched card indicated infection leaf leukemia Lymphoid Member Monopisthocotylea muscle mycelium nerve normal order of class[books.google.de]

    Missing: Mb2
  • Bordetella Bronchiseptica

    Invasion, defined as adhesion to, followed by entrance into HeLa cells by Bordetella bronchiseptica was determined by (i) specific staining of intracellular bacteria and (ii[ncbi.nlm.nih.gov] We also show that pagP is not required for the initial colonization of the mouse respiratory tract by B. bronchiseptica, but is required for persistence of the organism within[ncbi.nlm.nih.gov] Wild-type B. bronchiseptica (RB50) preferentially adhered to cilia and induced ciliated host cell Ca(2 ) transients within 2 min of coincubation, whereas coincubation with[ncbi.nlm.nih.gov] Abstract The type III secretion system (T3SS) is a sophisticated protein secretion machinery that delivers bacterial virulence proteins into host cells.[ncbi.nlm.nih.gov] The fimBCD locus is embedded within the fha operon, whose genes encode another putative adhesin, filamentous hemagglutinin (FHA).[ncbi.nlm.nih.gov] Abstract A narrow-spectrum clavulanic acid-inhibited class A beta-lactamase, BOR-1, was identified in a Bordetella bronchiseptica clinical isolate.[ncbi.nlm.nih.gov] Our results show that B. bronchiseptica flagellin is able to signal effectively through both human and mouse Toll-like receptor 5.[ncbi.nlm.nih.gov] From WikiVet English Bordetella bronchiseptica Phylum Proteobacteria Class Beta Proteobacteria Order Burkholderiales Family Alcaligenaceae Genus Bordetella Species B. bronchiseptica[en.wikivet.net]

    Missing: Mb2 histocompatibility
  • Taenia Solium

    […] proglottids, containing a self-contained hermaphrodite reproductive unit; eggs contain a fully developed, six-hooked (hexcanth) embryo; inhabits the human jejunum SECTION II[msdsonline.com] The mouse experiment indicated that vaccine strain χ4558 induced a high titer of specific antibody for a long time.[ncbi.nlm.nih.gov] Thomas LF 1, 2 , de Glanville WA 1, 2 , Cook EA 1, 2 , Bronsvoort BM 3 , Handel I 3 , Wamae CN 4, 5 , Kariuki S 4 , Fèvre EM 2, 6 .[ncbi.nlm.nih.gov] Subsequent proteome analysis of CC-Fas binary complex mediated protein-protein interactions revealed seven protein ligands in the TsM cellular proteins.[ncbi.nlm.nih.gov] Copyright 2018 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.[ncbi.nlm.nih.gov] […] nucleotide sequencing of a nuclear DNA gene, DNA polymerase delta (pold) revealed that all the tapeworms identified as T. asiatica using mtDNA had T. saginata type allele at pold locus[ncbi.nlm.nih.gov] Product overview Abcam’s anti-Taenia solium IgG Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the accurate qualitative measurement of IgG class[abcam.com] Electronic address: [email protected] 2 Department of Parasitology, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa 078-8510, Japan; Laboratory[ncbi.nlm.nih.gov]

    Missing: Mb2
  • Brucella Melitensis

    Twenty-seven pools of 500 major histocompatibility complex class II (MHC-II) restricted peptides were created by computational prediction of promiscuous MHC-II CD4( ) T cell[ncbi.nlm.nih.gov] In contrast, modified LPS with a defective core purified from Brucella carrying a mutated wadC gene (Bm-wadC), efficiently potentiated mouse and human DC activation and T[ncbi.nlm.nih.gov] B. melitensis RS-α and LS-2 were then expressed in Escherichia coli as fusion proteins with His tag.[ncbi.nlm.nih.gov] Eighty-eight immunoreactive protein spots from B. melitensis M5 were identified by Western blotting and were assigned to sixty-one proteins by mass spectrometry, including[ncbi.nlm.nih.gov] Many isolates were single-locus or double-locus variants of closely related B. melitensis isolates from different regions, including the north and south of China.[ncbi.nlm.nih.gov] PURPOSE: In the last few decades, increasing microbial resistance to common antibiotics has attracted researchers' attention to the development of new classes of antibiotics[ncbi.nlm.nih.gov] Here, we used a large panel of genetically deficient mice to compare the importance of B cells, transporter associated with antigen processing (TAP-1), and major histocompatibility[ncbi.nlm.nih.gov] In the serum II, IgM antibodies of 24,9 U/ml, and IgG antibodies of 311 U/ml were found.[ncbi.nlm.nih.gov]

    Missing: Mb2
  • Salmonella Infection

    Author information 1 a Institute of Biochemistry II, Goethe University School of Medicine , Frankfurt am Main , Germany.[ncbi.nlm.nih.gov] Heat-killed MLABs and cell-wall preparations were able to reduce the Salmonella invasion of Caco-2 and mouse macrophage cells.[ncbi.nlm.nih.gov] Epithelial cells with claudin-2 knockdown had significantly less internalized Salmonella than control cells with normal claudin-2 expression.[ncbi.nlm.nih.gov] RESULTS: Recombinant proteins representing the large extracellular domains of tetraspanins inhibited binding of S.[ncbi.nlm.nih.gov] Copyright 2012 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.[ncbi.nlm.nih.gov] As mice with the susceptible Nramp1 locus get systemic infection with serovar Typhimurium, murine infection models using this serovar have been widely used to decipher the[ncbi.nlm.nih.gov] We report that Class II PI3-kinase beta isoform, IPMK and other kinases identified from a kinase screen all contribute to Akt activation during Salmonella infection.[ncbi.nlm.nih.gov] […] from human clinical cases, livestock, wild mammals and birds in Scotland, UK to characterize possible transmission routes using pulsed-field gel electrophoresis and multi-locus[ncbi.nlm.nih.gov]

    Missing: Mb2
  • Intramuscular Injection

    We conducted a Phase II study to evaluate the safety of oral administration of vitamin B12 in patients with advanced non-small cell lung cancer who received pemetrexed single[ncbi.nlm.nih.gov] Although recent data suggest that αS pathology can spread within the mouse brain, there is no direct evidence for spread of disease from a peripheral site.[ncbi.nlm.nih.gov] […] intramuscular hydroxocobalamin injection with a 3-month course of 1mg/day sublingual methylcobalamin supplements on serum vitamin B12 concentrations in participants withtype 2[ncbi.nlm.nih.gov] In addition, the sera from the rats with intramuscular injections of AAV9-hEPO contained greater levels of antibodies against both AAV9 capsid protein and hEPO protein than[ncbi.nlm.nih.gov] DISCUSSION: Muscle pain and spreading hyperalgesia induced by NGF is maintained despite anesthesia of the primary nociceptive locus.[ncbi.nlm.nih.gov] METHODS/DESIGN: This phase II clinical trial is a single-center, prospective, randomized, double-blind, placebo-controlled with 2 arms.[ncbi.nlm.nih.gov] Two approaches were used to analyse these data: (i) a non-compartmental approach; and (ii) a compartmental modelling approach.[ncbi.nlm.nih.gov] Serotype 2 AAV vector (rAAV2/2) was also investigated, but long-term phenylalanine clearance has been observed only for pseudotypes 1 and 8.[ncbi.nlm.nih.gov]

    Missing: Mb2