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80 Possible Causes for 2 5A, tetramer

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  • Rhinovirus

    Peptide epitopes of the RV-A16 capsid proteins VP1 and VP2 were identified by peptide/MHC class II tetramer-guided epitope mapping, validated by direct ex vivo enumeration[ncbi.nlm.nih.gov] Cells were washed twice with PBS (Ca 2 and Mg 2 free). Finally, 1 mL of fresh McCoy's 5A Medium–2% FCS was added in each well and cells were incubated at 33 C.[journals.plos.org] Cross-reactivity was evidenced by identification of a common *0401-restricted epitope for RV-A16 and RV-A39 by tetramer-guided epitope mapping and the ability for RV-A16-specific[ncbi.nlm.nih.gov]

  • Trifluoperazine

    Addition of the two drugs to HbNO shifted the conformational equilibrium from the high- to the low-affinity form of the ligated tetramer, as observed for 2,3-D-glycerate bisphosphate[ncbi.nlm.nih.gov] Agonists: Ergolines (e.g., 2-Br-LSD (BOL-148) , ergotamine , LSD ) Serotonin (5-HT) Tryptamines (e.g., 5-CT ) Valerenic Acid Antagonists: Asenapine Latrepirdine (dimebolin[en.wikipedia.org] Renzapride RS-67333 RS-67506 Serotonin (5-HT) Tegaserod Velusetrag Zacopride Antagonists: GR-113808 GR-125487 L-Lysine Piboserod RS-39604 RS-67532 SB-203186 SB-204070 5-HT 5A[en.wikipedia.org]

  • Shigella Flexneri

    Both of these forms of IpaB associate with membranes, however, only the tetramer forms pores in liposomes.[ncbi.nlm.nih.gov] S. flexneri is divided into at least 20 serotypes (serotypes 1a, 1b, 1c, 1d, 2a, 2b, 2 variant, 3a, 3b, 4a, 4av, 4b, 5a, 5b, X, Xv, Y, Yv, F6, and 7b) based on the combinations[frontiersin.org] Figure 1 Electron micrograph of phage Sf101 negatively stained with 2% phosphotungstic acid. Scale bar, 50 nm.[bmcgenomics.biomedcentral.com]

  • Chronic Myelomonocytic Leukemia

    Simultaneously, the percentage of WT1-specific CTLs as measured by the HLA-WT1 tetramer assay increased.[ncbi.nlm.nih.gov] […] methods ( r 0.85, R 2 value 0.73, P 0.0001) ( Supplemental Figure 5A ).[jci.org] As shown in Figure 6A , a direct comparison of the 2 groups of patients identified 601 genes with an absolute log 2 fold change greater than 1 and a P value of less than 0.05[jci.org]

  • Colorectal Carcinoma

    We found that MAIT cells, defined as CD3ε Vα7.2 CD161 or CD3ε MR1 tetramer cells, were present within both healthy and tumor-afflicted hepatic tissues.[ncbi.nlm.nih.gov] […] interval between the samples was 2 years and 11 months.[journals.plos.org] Copy number profiles of both the primary tumor (PT5) and a plasma sample (P5_1) obtained after panitumumab treatment had marked similarities ( Figure 5a ), although the time[journals.plos.org]

  • Carcinoma

    However, the classical method for labeling CTLs, major histocompatibility complex (MHC)-peptide tetramer, has drawbacks and needs further improvement.[ncbi.nlm.nih.gov] First described by Young and Zukerberg in 1991, 27 , 28 , 29 only Figure 5a and b ).[nature.com] The cysts are round to oval or slit-like, sometimes measuring 1–2 mm and contain secretions that may be targetoid; occasionally they may be calcified.[nature.com]

  • Dejerine-Sottas Disease

    At present it is anticipated that four P 0 proteins form a tetramer and link to a tetramer of the opposed membrane.[bmcresnotes.biomedcentral.com] CMT) IA (PMP-22 Point mutation) HMSN (CMT) ID (EGR2) CMT 2A2 (MFN2) HMSN (CMT) 2C (TRPV4) CMT 4A & CMT 2K (GDAP1) Other motor Distal HMN VII (2q14) Distal HMN Vocal cord 2[neuromuscular.wustl.edu] X-ray crystallography suggests that P 0 ex emanate from the membrane surface as tetramers that link to tetramers on the opposing membrane surface, to result in the formation[bmcresnotes.biomedcentral.com]

  • X-Linked Agammaglobulinemia

    Influenza virus-specific CD4 IFN-γ and CD8 IFN-γ T cells and HLA-A2/M158–66-tetramer CTLs could be induced by TIV in XLA patients, and the levels and duration of maintaining[ncbi.nlm.nih.gov] Localization Nucleotide aberration Amino acid aberration Protein domain P 2 Exon 18 c.1762T G p.W588G TK P 4 Exon 2 c.40T C p.S14P PH P 5a Exon 13 c.1157_1161delCCACT p.S386fsX10[intechopen.com] 0 31 0 (–) (–) P 5a 3.5 - - - 0 ( ) (–) P 5b 3 months 21 3 0 ( ) (–) P 6 1.5 611 179 55 2 (–) ( ) P 7 1.5 157 0 (–) (–) P 8 8 307 28 121 0 (–) ( ) P 9 6 0 28 0 (–) (–) P 10[intechopen.com]

  • Nonketotic Hyperglycinemia

    Instead, novel alphabeta-type dimers associate to form an alpha(2)beta(2) tetramer, where the alpha- and beta-subunits are structurally similar and appear to have arisen by[ncbi.nlm.nih.gov] DHCR7) Charcot-Marie-Tooth Typ 1D (EGR2) Spastische Paraparese Typ 1 (L1CAM) Charcot-Marie-Tooth Typ 1F (NEFL) Spastische Paraparese Typ 2 (PLP1) Charcot-Marie-Tooth Typ 2[yumpu.com] Thus, the tetramer can be described as a dimer of heterodimers.[emboj.embopress.org]

  • Simpson Dysmorphia Syndrome

    The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.[creativebiolabs.net] ACHN and A-498 cells were cultured in a MEM Alpha medium (Gibco by Life Technologies, Grand Island, NY, USA), CaKi-1 and CaKi-2 cells were cultured in a McCoy’s 5A medium[bmccancer.biomedcentral.com] This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of GPC3-derived peptide of FVGEFFTDV sequence covering 144-152 and A*02:01[creativebiolabs.net]

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