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7,957 Possible Causes for 28, domain, repeat, tetratricopeptide

  • Novobiocin

    Abstract The C-terminal domain of Hsp90 displays independent chaperone activity, mediates dimerization, and contains the MEEVD motif essential for interaction with tetratricopeptide[ncbi.nlm.nih.gov] In enrichment plating using NBGL, this figure was 82% (vs. 26% and 28%).[ncbi.nlm.nih.gov] Treatment cycles were repeated every 4 weeks.[ncbi.nlm.nih.gov] We now report that novobiocin synergistically enhanced the sensitivity of the multidrug resistant variants, WEHI-3B/NOVO and A549(VP)28, to VP-16, causing almost complete[ncbi.nlm.nih.gov]

  • Gigantism

    The Q229X mutation was predicted to generate a truncated AIP protein, lacking the last two tetratricopeptide repeat domains and the final C-terminal α-7 helix.[ncbi.nlm.nih.gov] Elevated basal GH (mean 28 micrograms/l) and PRL (mean 120 micrograms/l) plasma levels were observed, as well as paradoxical responses of GH to L-dopa, TRH and oral glucose[ncbi.nlm.nih.gov] The HMGI-C protein has three AT-hook domains and an acidic COOH-terminal tail.[ncbi.nlm.nih.gov] Four of the nine patients who failed the initial surgery required a repeat procedure.[ncbi.nlm.nih.gov]

  • Influenza

    We reported a 28-year-old healthy woman presented with subacute onset ascending muscle weakness 2 weeks after an annual influenza vaccination.[ncbi.nlm.nih.gov] For instance, the H3 HA has less disparity in mutational tolerance between the head and stalk domains than the H1 HA.[ncbi.nlm.nih.gov] CLINICAL CASE: A patient that after seven years on NTZ therapy, testing on every 3 months repeated evaluations negative for anti-JCV status became positive ( 3 units) 4 weeks[ncbi.nlm.nih.gov] […] influenza and Tdap vaccination coverage among women pregnant during the 2017-18 influenza season, CDC analyzed data from an Internet panel survey conducted during March 28[ncbi.nlm.nih.gov]

    Missing: tetratricopeptide
  • Epilepsy

    Leu729ThrfsTer6) in TMTC3, encoding transmembrane and tetratricopeptide repeat containing 3, in four siblings with nocturnal seizures and ID.[ncbi.nlm.nih.gov] RESULTS: In this study ( n 99), 35 women received carbamazepine, 28 received LEV, 15 received valproate (VPA), 13 received phenytoin (PHT), three each received oxcarbazepine[ncbi.nlm.nih.gov] PURPOSE: Dishevelled EGL-10 and pleckstrin domain-containing protein 5 (DEPDC5) mutations are found in a wide spectrum of focal epilepsies ranging from epilepsy caused by[ncbi.nlm.nih.gov] A 27-year-old woman with a history of epilepsy and anti-epileptic drugs (AEDs) developed repeated seizures and neuropsychiatric symptoms after a 9-year asymptomatic interval[ncbi.nlm.nih.gov]

  • Treponema Denticola

    These genes include a four-member family of YD repeat proteins (carbohydrate-binding), 11 tetratricopeptide (TPR) repeat-containing proteins (protein–protein interactions)[pnas.org] […] the prevalence of T. denticola in whole saliva samples from patients with chronic periodontitis (CP, n 37), aggressive periodontitis (AgP, n 24), and healthy subjects (n 28[ncbi.nlm.nih.gov] Treponema denticola sonicates adhered to recombinant Rgp domains.[ncbi.nlm.nih.gov] Abstract The gene lrrA, encoding a leucine-rich repeat protein, LrrA, that contains eight consensus tandem repeats of 23 amino acid residues, has been identified in Treponema[ncbi.nlm.nih.gov]

  • Suramin

    In the absence of S100 proteins, suramin bound to the tetratricopeptide repeat (TPR) domain of PP5 and activated the enzyme in a dose-dependent manner.[ncbi.nlm.nih.gov] […] of each 28-day cycle) schedule.[ncbi.nlm.nih.gov] The docking results of both hFGF1-FGFR2 D2 domain and hFGF1-suramin complex were superimposed.[ncbi.nlm.nih.gov] Abstract The paper records the numbers of 1-2 mm shotty papules developing in the author's skin after 2-day courses of diethylcarbamazine (DEC) repeated every 16 days before[ncbi.nlm.nih.gov]

  • Pharyngitis

    Clin Rheumatol. 2009 Oct;28(10):1235-7. doi: 10.1007/s10067-009-1222-z. Epub 2009 Jul 11.[ncbi.nlm.nih.gov] As a result, the mutant CARD8 protein lost the ability to interact with the NOD domain of NLRP3.[ncbi.nlm.nih.gov] VCI resulting from a malignant tumor was suspected at first, but repeated pathological examinations revealed CMV infection in the pharyngeal mucosa.[ncbi.nlm.nih.gov] RESULTS: A total of 28 511 episodes of pharyngitis in 19 865 children aged 0-18, recorded by 125 physicians, were analysed (average of 1.4 episodes per child).[ncbi.nlm.nih.gov]

    Missing: tetratricopeptide
  • Parainfluenza Virus

    The IFIT (interferon-induced proteins with tetratricopeptide repeats) family proteins constitute a major subclass of ISG proteins and are characterized by multiple tetratricopeptide[ncbi.nlm.nih.gov] RESULTS: Out of these specimens, 1675 (6.50%, 1675/25,773) showed HPIV positive, including 261 (1.01%, 261/25,773) for HPIV1, 28 (0.11%, 28/25,773) for HPIV2, and 1388 (5.39%[ncbi.nlm.nih.gov] IMPORTANCE We examined the importance of amino acids in the putative RNA-binding domain of hPIV2 NP for polymerase activity using minireplicons.[ncbi.nlm.nih.gov] CONCLUSION: The developed one-step mRT-PCR in this study is an effective and specific assay for clinical diagnosis of HPIV1 to 4 (Tab. 1, Fig. 6, Ref. 28).[ncbi.nlm.nih.gov]

  • Nephronophthisis

    […] repeat domain 21B tetratricopeptide repeat domain-containing protein 21B tetratricopeptide repeat-containing hedgehog modulator 1 TTC21B THM1 612014 25660 transmembrane protein[ukgtn.nhs.uk] In an attempt to identify such genetic determinants, a cohort of 28 families with nephronophthisis and at least one JS-related neurologic symptom were screened for mutations[ncbi.nlm.nih.gov] Specifically, the R650C substitution is located within a G[QRC]LG repeat motif of the predicted seven bladed beta-propeller structure of the RCC1 domain.[ncbi.nlm.nih.gov] Compared with the previous approach, MIPs redetected 66 out of 78 variants and 28 previously unidentified variants, for a total of 94 variants.[ncbi.nlm.nih.gov]

  • Nontuberculous Mycobacteria

    Epub 2015 May 28.[ncbi.nlm.nih.gov] Abstract Since pulmonary nontuberculous mycobacteria (PNTM) lung disease was last reviewed in CHEST in 2008, new information has emerged spanning multiple domains, including[ncbi.nlm.nih.gov] The absence of asthma, the inability to isolate fungi and the repeated isolation of NTM made it difficult to differentiate allergic bronchopulmonary aspergillosis from NTM[ncbi.nlm.nih.gov] The diagnosis is based on repeated isolations of the same mycobacterium associated with clinical and radiological signs, and the absence of tuberculosis.[ncbi.nlm.nih.gov]

    Missing: tetratricopeptide