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5,984 Possible Causes for 3,, Aldehyde, homolog, oxidase, rat

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  • Aldehyde

    An inhibition study suggested that monoamine oxidase-B (MAO-B) oxidizes KW-2449 to an iminium (intermediate) and aldehyde oxidase (AO) then metabolizes the intermediate to[ncbi.nlm.nih.gov] Chem Res Toxicol. 2017 Mar 20;30(3):785-793. doi: 10.1021/acs.chemrestox.6b00315. Epub 2017 Mar 1.[ncbi.nlm.nih.gov] […] by single-species scaling (SSS) or multispecies allometry (MA), we scaled in vitro intrinsic clearance (CL int ) of five AO substrates obtained from hepatic S9 of mouse, rat[ncbi.nlm.nih.gov] Some aldehydes are substrates for aldehyde dehydrogenase enzymes which metabolize aldehydes in the body.[en.wikipedia.org] GRP78), protein kinase R-like ER kinase (PERK), phosphorylated eukaryotic translation initiation factor α subunit (p-eIF2α), activating transcription factor-4 (ATF-4), CEBP homologous[ncbi.nlm.nih.gov]

  • Xanthinuria

    The residual xanthine oxidase from the parents exhibited normal kinetics with respect to hypoxanthine.[ncbi.nlm.nih.gov] This condition is inherited recessively and is caused by a congenital defect of a molybdenum-containing cofactor essential for the function of 3 distinct enzymes (ie, xanthine[emedicine.com] Purine Nucleotide Catabolism in Rat Liver.[researchgate.net] Moreover, Arg776 is conserved in a diversity of eukaryotic and prokaryotic proteins that posses a domain homologous to the C-terminal domain of HMCS.[ncbi.nlm.nih.gov] Uric acid was too small to be measured but uricase determination showed only 3 mg/24 hr. Serum oxypurine analysis showed hypoxanthine 0.87 mg/dl and xanthine 0.35 mg/dl.[ncbi.nlm.nih.gov]

  • Deficiency of Sulfite Oxidase

    Abstract Isolated sulfite oxidase (SO) deficiency is an autosomal recessively inherited inborn error of sulfur metabolism.[ncbi.nlm.nih.gov] Abstract In a 3-week old female child with clinical features including neurologic abnormalities and lens dislocation, xanthinuria co-existed with increased excretion of sulfur[ncbi.nlm.nih.gov] In the in vivo experiments, although RBC deformability was not affected by sulfite treatment in SOXD rats, it was found to be significantly increased in SOXC rats.[ncbi.nlm.nih.gov] The cofactor is essential for the function of the human enzymes sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase.[ommbid.mhmedical.com] The structural characterization of these mutants is now possible after the chicken sulfite oxidase gene has been synthesized chemically and due to the high homology to the[ncbi.nlm.nih.gov]

  • Pargyline

    Abstract During 4 weeks of treatment with clorgyline, a selective MAO-A inhibitor, platelet monoamine oxidase (MAO) activity was unchanged.[ncbi.nlm.nih.gov] Abstract Three TEMPO-conjugated pargyline analogues (ParSL-1, ParSL-2, and ParSL-3) have been synthesized and their inhibitory properties tested for the two human monoamine[ncbi.nlm.nih.gov] Abstract A single dose of pargyline severely depleted hepatic reduced glutathione (GSH) levels in the rat.[ncbi.nlm.nih.gov] Reductases 173 Mechanism of the Magnesium Ion Activation of 181 Kinetic Studies on NADPHLinked Aldehyde Reductase 189 Structure of Cytochrome c Oxidase 197 Acetaldehyde Directly[books.google.com] These molecules target two homologous enzymes, monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B), differentially expressed throughout the body and brain, both of[doi.org]

  • Xanthinuria Type 1

    Allopurinol was metabolized to oxypurinol and pyrazinamide to 5-hydroxypyrazinamide in spite of no activity of xanthine oxidase, suggesting that aldehyde oxidase converted[ncbi.nlm.nih.gov] Kimiyoshi Ichida 3 Ichiei Narita 4 1.[link.springer.com] […] and AntiHIV Activity of Phosphoramidate Derivatives of D4TMP 753 Determination of Purine Enzyme Activities in Human Erythrocytes 759 EctoNucleotidases in Isolated Intact Rat[books.google.com] […] allopurinol to oxipurinol during an allopurinol loading test for determining the type of classical xanthinuria revealed that the patients had classical type 1 xanthinuria, because aldehyde[ncbi.nlm.nih.gov] Egl nine homolog 1 Egl nine homolog 2 Egl nine homolog 3 Fumarate hydratase, mitochondr... Hypoxia-inducible factor 1-alp... Isocitrate dehydrogenase [NAD]...[smpdb.ca]

  • Xanthinuria Type 2

    So I guess the main question is: What band size would you expect for catalyticly active xanthine oxidase, 150 kDa or 80 kDa?[abcam.com] Business Media , ٢٧‏/٠١‏/٢٠١٤ - 573 من الصفحات MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3[books.google.com] […] and AntiHIV Activity of Phosphoramidate Derivatives of D4TMP 753 Determination of Purine Enzyme Activities in Human Erythrocytes 759 EctoNucleotidases in Isolated Intact Rat[books.google.de] Also Known As Xanthine dehydrogenase and xanthine aldehyde oxydase dual deficiency[codelay.com] Als ein zu den C-Termini der Moco-Sulfurasen homologes Protein wurde das „mitochondrial amidoxime reducing component“-Protein mARC aus Schweinelebermitochondrien identifiziert[publikationsserver.tu-braunschweig.de]

  • Disulfiram

    Abstract Human diamine oxidase (hDAO, EC 1.4.3.22) is the key enzyme in the degradation of extracellular histamine.[ncbi.nlm.nih.gov] Dosage Exhibit 3-3 summarizes standard dosage information for disulfiram.[ncbi.nlm.nih.gov] Employing microdialysis sampling, DETC-NAC levels in the nucleus accumbens (NAc), medial prefrontal cortex (mPFC), and plasma of rats treated with DSF reached 1.1, 2.5 and[ncbi.nlm.nih.gov] Disulfiram (DSF), an inhibitor of aldehyde dehydrogenase, is currently in clinical use for treating alcoholism.[ncbi.nlm.nih.gov] Reduction of EGFR phosphorylation disables recruitment of multiple Src homology 2 (SH2) domains, resulting in transcriptional down-regulation of VEGF.[ncbi.nlm.nih.gov]

  • Molybdenum Cofactor Deficiency Complementation Group B

    Sulfite oxidase deficiency and molybdenum cofactor deficiency in the metabolism of sulfated amino acids. Pictured is an infant with sulfite oxidase deficiency.[emedicine.medscape.com] Babies with microcephaly often have smaller 3 ... ... More on Microcephaly » Thick vermilion border : Summary : Increased width of the \ 4 , 5 ... ...[familydiagnosis.com] […] catalysing diverse redox reactions, however, only four of them have been found in plants. (1) Nitrate reductase catalyses the key step in inorganic nitrogen assimilation, (2) aldehyde[paperity.org] Our data support the view that the MogA-like domain of gephyrin is indeed the mammalian homolog of the E. coli protein MogA, and gephyrin is the direct homolog of the plant[pnas.org] Chem. 278 14523-14532 2003 - - 1 - 9 - - - - - - 1 - 3 - - 1 1 - - - - 1 2 1 - - - 1 - - - - - - - - 1 - - 9 - - - - - - - - 1 - - - 1 - - - - 1 2 1 - - - 1 - - - - 3 3 -[brenda-enzymes.org]

  • Malignant Neoplasm

    Reduction of lysyl oxidase (LOX), a copper-dependent amine oxidase that catalyses the crosslinking of collagens, elastin, and fibrillin in the ECM [ 7 ] reduces matrix stiffening[doi.org] , Multi-Targeted Approach to Treatment of Cancer , 10.1007/978-3-319-12253-3_2 , (19-56) , (2014) .[doi.org] Early contact inhibition in naked mole-rat fibroblasts. Growing and confluent naked mole-rat ( A ) and mouse ( B ) fibroblasts.[pnas.org] Reznick and Dror Aizenbud , Oxidative damage in keratinocytes exposed to cigarette smoke and aldehydes , Toxicology in Vitro , 28 , 4 , (485) , (2014) .[doi.org] The resultant DSB induced homologous recombination.[doi.org]

  • Acute Gastroenteritis

    Media used to isolate bacteria responsible for gastroenteritis include the following: Blood agar: All aerobic bacteria and yeast; detects cytochrome oxidase production MacConkey[emedicine.medscape.com] We present a case report of a 3-month-old child with acute gastroenteritis who visited a pediatric clinic in Kyushu area in Japan in 2015.[ncbi.nlm.nih.gov] Infect Dis J 25:577–583 PubMed CrossRef Google Scholar Crawford SE, Patel DG, Cheng E et al (2006) Rotavirus viremia and extraintestinal viral infection in the neonatal rat[link.springer.com] Sequencing of a portion of the capsid gene and the ORF1/ORF2 overlap was used to assess DNA sequence homology, phylogeny, and recombination using pairwise alignments, MEGA[ncbi.nlm.nih.gov] Two GI.3 was detected in nasopharyngeal swab.[ncbi.nlm.nih.gov]

    Missing: Aldehyde

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