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4,272 Possible Causes for 3,, carbonyl, human, reductase

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  • Influenza

    Immune-mediated necrotizing myopathy may be associated with myositis-specific autoantibodies including anti-single recognition particle and anti-3-hydroxy-3- methylglutaryl-coenzyme A reductase[ncbi.nlm.nih.gov] This restoration of pH occurs much more slowly than the re-alkalinization of cells treated with the protonophore carbonyl cyanide p -trifluoromethoxyphenylhydrazone ( 27 )[doi.org] […] years, using data from a cohort study with 266 children who had received 2 doses (0.25 mL/dose for 3 years old, 0.5 mL/dose for 3 years old) in the 2006/2007 season.[ncbi.nlm.nih.gov] The rapid evolution of influenza A and B viruses contributes to annual influenza epidemics in humans.[ncbi.nlm.nih.gov]

  • Aldehyde

    Two peaks of reductase activity corresponding to aldose reductase and aldehyde reductase were observed when sympathetic ganglia were chromatofocused.[ncbi.nlm.nih.gov] Resonance Treatment of the Carbonyl Pi Bond 1.[research.cm.utexas.edu] Chem Res Toxicol. 2017 Mar 20;30(3):785-793. doi: 10.1021/acs.chemrestox.6b00315. Epub 2017 Mar 1.[ncbi.nlm.nih.gov] KEYWORDS: Activity; Human salivary aldehyde dehydrogenase; Stability; Storage[ncbi.nlm.nih.gov]

  • Lovastatin

    Assay for HMG-CoA Reductase Activity. The HMG-CoA reductase assays in MDA-MB-157 cells were performed as described ( 27 ).[doi.org] Parents Fatty acid esters Oxanes Dicarboxylic acids and derivatives Secondary alcohols Carboxylic acid esters Oxacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl[hmdb.ca] In the fruiting bodies of the fungus Pleurotus ostreatus, also called the oyster mushroom, we found a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin[ncbi.nlm.nih.gov] […] that is hydrolysed in vivo to β-hydroxy acid lovastatin, which inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-Co-A) reductase (HMGR), thereby lowering cholesterol in humans[ncbi.nlm.nih.gov]

  • Osteoporosis

    This process involves two enzymes, γ-glutamyl carboxylase and vitamin K epoxide reductase (VKORC1).[ncbi.nlm.nih.gov] 264.7 macrophage cell line (from murine blood)/Er-Xian Decoction treatment In osteoblasts: 8 proteins upregulated Hmgb1, acidic ribosomal phosphoprotein P0, histone H2, carbonyl[doi.org] […] and n–3 fatty acids ( 14 ).[ajcn.org] Vertebrae from young adult humans and chimpanzees, gorillas, orangutans, and gibbons (T8 vertebrae, n   8-14 per species, male and female, humans: 20-40 years of age) were[ncbi.nlm.nih.gov]

  • Fluvastatin

    Product name Fluvastatin sodium salt, HMG-CoA reductase inhibitor Description Competitive HMG-CoA reductase inhibitor Biological description Competitive HMG-CoA reductase[abcam.com] […] fatty acids Aryl fluorides Heteroaromatic compounds Secondary alcohols Carboxylic acids Azacyclic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Carbonyl[hmdb.ca] Marsh A 1 , Casey-Green K 1 , Probert F 1 , Withall D 1 , Mitchell DA 2 , Dilly SJ 3 , James S 4 , Dimitri W 4 , Ladwa SR 3 , Taylor PC 1 , Singer DR 4, 5, 2 .[ncbi.nlm.nih.gov] Human P2X(2) was insensitive to cholesterol depletion.[ncbi.nlm.nih.gov]

  • Chenodeoxycholic Acid

    Patient 2 received a combined treatment with LDL-apheresis, CDCA and HMG-CoA reductase inhibitor.[ncbi.nlm.nih.gov] […] alcohols and derivatives Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl[foodb.ca] Abstract We report 3 sisters treated for cerebrotendinous xanthomatosis.[ncbi.nlm.nih.gov] […] in human primary white adipocytes.[ncbi.nlm.nih.gov]

  • Finasteride

    Finasteride is the first 5alpha-reductase inhibitor that received clinical approval for the treatment of human benign prostatic hyperplasia (BPH) and androgenetic alopecia[ncbi.nlm.nih.gov] The treatment (5 h previously) of mice with the 5α-reductase inhibitor SKF 105111 (17β-17-[ bis (1methylethyl) amino carbonyl]; Figure 1 ) resulted in a reduction in the decay[doi.org] AIM: To evaluate the effectiveness of finasteride and dutasteride on hair loss in women with androgenetic alopecia over a period of 3 years.[ncbi.nlm.nih.gov] There are two isozymes of 5α-reductase in humans.[google.com]

  • Pravastatin

    […] procedures of LDL-apheresis without drug therapy, combination therapy with LDL-apheresis and CS-514 (eptastatin), an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme (HMG-CoA) reductase[ncbi.nlm.nih.gov] […] acids Beta hydroxy acids and derivatives Dicarboxylic acids and derivatives Secondary alcohols Carboxylic acid esters Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl[hmdb.ca] However, the preclinical evidence supporting pravastatin as a treatment is limited to animal models, with almost no studies in human tissues.[ncbi.nlm.nih.gov] A low n-3 to n-6 polyunsaturated fatty acid (PUFA) ratio is associated with cardiovascular events.[ncbi.nlm.nih.gov]

  • Rosuvastatin

    Crestor Pharmacologic Category Antilipemic Agent, HMG-CoA Reductase Inhibitor Pharmacology Inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting[drugs.com] The tunable functionality of α,β-unsaturated carbonyl compounds enables their differential application in biological systems . ChemMedChem 5 , 351–356 (2010). 141.[nature.com] (OM-3) fatty acids.[ncbi.nlm.nih.gov] We tested whether atorvastatin and rosuvastatin are direct ligands of human constitutive androstane receptor (CAR).[ncbi.nlm.nih.gov]

  • Dihydrofolate Reductase Deficiency

    Dihydrofolic acid reductase deficiency prevents this conversion of folic acid to tetrahydrofolic acid; the enzyme activity appears to differ in each patient.[ncbi.nlm.nih.gov] […] derivatives Heteroaromatic compounds Amino acids Secondary carboxylic acid amides Ketimines Propargyl-type 1,3-dipolar organic compounds Carboxylic acids Azacyclic compounds Carbonyl[hmdb.ca] PubMed (3) All databases (10) Download RDF DBGET integrated database retrieval system[genome.jp] Human dihydrofolate reductase has also been used in a study to investigate the structural analysis of human dihydrofolate reductase as a binary complex.[sigmaaldrich.com]