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507 Possible Causes for 3 ((3 (ethoxymethyl) 5 fluoro 3,6 dihydro 2,6 dioxo 1(2H) pyrimidinyl)carbonyl) ,, 6 (benzoyloxy) 3 cyano 2 pyridinyl, Benzoic, acid,, ester

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  • Aristolochic Acid

    Coincubation with L-lactic acid or benzoic acid, typical substrates for the proton-linked monocarboxylic acid transporters (MCTs), significantly decreased the AAI uptake,[ncbi.nlm.nih.gov] We conclude from these studies that AL-NOHs, formed following partial nitroreduction of aristolochic acids, serve as substrates for SULT1B1, producing N-sulfated esters, which[ncbi.nlm.nih.gov] […] amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- (CAS) ; N-(4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoyl)glutamic acid ; N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin[easychem.org] […] argemonine Aristolactam aristolochic acid aromatic Aslanov biosynthesis carbonyl catalytic hydrogenation Chem chloride cyclization derivative dibenzopyrrocoline double bond ester[books.google.com] Chemical element Complexometric indicator Coordination compounds Coumarins Crown ether Cycloalkane Cytokinin Diatomic molecule Diene Diolefin Double salt Dye Emulsifiers Ester[charchem.org] […] decreased the uptake of AAI by Caco-2 cells cultured on the dishes at pH 7.4, and a similar decrease in AAI uptake was found when the cells were coincubated with acetic acid or benzoic[ncbi.nlm.nih.gov] Abstract Aristolochic acid (AA), a plant nephrotoxin and carcinogen, causes aristolochic acid nephropathy (AAN) and its associated urothelial malignancy, and is hypothesized[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Valproic Acid

    During valproic acid treatment, it is difficult for prescribers to predict its individual response.[ncbi.nlm.nih.gov] Benzoic acid was used as an internal standard (IS).[ncbi.nlm.nih.gov] The ester bonds in 1 a-3 a can be hydrolyzed quickly by esterase and display similar inhibition of HDAC activity to VPA.[ncbi.nlm.nih.gov] ., and Eadie, M. pH- dependent rearrangement of the biosynthetic ester glucuronide of valproic acid to beta- glucuronidase- resistant forms Drug Metab.[caymanchem.com] 216476) 4-Hydroxy Valproic Acid Sodium Salt (Mixture of Diastereomers) (sc-216870) rac 5-Hydroxy Valproic Acid Sodium Salt (sc-208266) Valproic Acid β-D-Glucuronide Allyl Ester[scbt.com] Although renal involvement is an uncommon adverse effect of valproic acid, Fanconi syndrome due to valproic acid therapy has rarely been reported.[ncbi.nlm.nih.gov] In a previous 12-week randomized trial we assessed the efficacy of the combination of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) with valproic acid, in comparison[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Azelaic Acid

    The bacterial degradation of nonanoic acid gives azelaic acid.[en.wikipedia.org] Bacteria were grown in defined media using continuous culture and delta pH was estimated by measuring the accumulation of [14C] benzoic by the cells using flow dialysis.[ncbi.nlm.nih.gov] […] polyoxyethylene fatty acid ester), cutina CBS (mixture of mono-dicglyceridene, fatty alcohols, triglycerides and wax esters), cetearyloctanoate, propylene glycol, glycerol 85%, benzoic[inhousepharmacy.vu] Nonmedicinal ingredients: benzoic acid (as preservative), disodium edetate, lecithin, medium-chain triglycerides, polyacrylic acid, polysorbate 80, propylene glycol, purified[uniprix.com] Abstract Azelaic acid (AzA) is a naturally occurring dicarboxylic acid that has a long and complex history in the treatment of skin disorders.[ncbi.nlm.nih.gov] […] the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters[thegoodscentscompany.com] The combination of azelaic acid and glycolic acid is a useful alternative to tretinoin, being at least as efficacious as the latter, while offering a superior tolerability[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Coffee

    KEYWORDS: Chlorogenic acid; Coffee; Digestibility; Esterase; Flavour[ncbi.nlm.nih.gov] Markers related to treatment were metabolites related to polyphenol administration as hippuric acid, benzoic acid derivatives, dihydroferulic and dihydrosinapic acid sulphate[ncbi.nlm.nih.gov] Dihydrohydroxycinnamate esters (dihydroferuloyl-, dihydrocaffeoyl- and dihydrocoumaroylquinic acids) have been identified for the first time in both plasma and urine, with[ncbi.nlm.nih.gov] Five monoacyl and three diacyl esters of trans-cinnamic acids and quinic acid were identified by ultra-performance liquid chromatography/electrospray ionization-quadruple[ncbi.nlm.nih.gov] KEYWORDS: chlorogenic acids; fat oxidation; hydroxyhydroquinone; oxidative stress[ncbi.nlm.nih.gov] Abstract A p-coumaroyl esterase from Rhizoctonia solani was used to decrease 5-O-chlorogenic acid (5-CQA) content in coffee powder.[ncbi.nlm.nih.gov] Markers related to treatment were metabolites related to polyphenol administration as hippuric acid, benzoic acid derivatives, dihydroferulic and dihydrosinapic acid sulphate[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Polygala Tenuifolia

    […] in thiobarbituric acid reactive substances (TBARS) level.[ncbi.nlm.nih.gov] The structure of 1 was elucidated by spectroscopic and physiochemical analysis as an oligosaccharide esterified with acetic, benzoic and p-hydroxycinnamoyl acid.[ncbi.nlm.nih.gov] Oligosaccharide esters isolated from plants of Polygalaceae. Chinese Traditional & Herbal Drugs 954–958 (2002). 5. Ito, H. et al .[nature.com] […] be components of the protein-bound polysaccharide analyzed by automatic amino acid analyzer.[ncbi.nlm.nih.gov] Two acidic polysaccharide fractions (PTPa and PTPb) extracted from the roots of Polygala tenuifolia, were obtained by DEAE-Sephacel anion-exchange, and Sephadex G-100 gel-permeation[ncbi.nlm.nih.gov] ., a new oligosaccharide ester, tenuifoliose Q (1), was isolated together with three known compounds.[ncbi.nlm.nih.gov] It consisted of galactose, glucose and galactose in the ratio of 3.1:3.7:2.5, and a small amount of rhamnose, mannose and xylose. 17 general amino acids were identified to[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Lonicera

    2779 vs 4753), 3-hydroxycinnamic (143 vs 351), p-coumaric (182 vs 271), isoferulic (805 vs 1570), ferulic (1086 vs 2395), and hippuric (194833 vs 398711 μg/mg creatinine) acids[ncbi.nlm.nih.gov] Abstract Five caffeoylquinic acids and esters (1-5), including a new compound, 3,5-dicaffeoylquinic acid butyl ester (5), were isolated from the flowers and buds of Lonicera[ncbi.nlm.nih.gov] In the prevention of hydrogen peroxide-induced endothelial cell injury in culture, protocatechuic acid, methyl caffeate, methyl chlorogenic acid and luteolin were significantly[ncbi.nlm.nih.gov] […] of the monosaccharides from 2M trifluoracetic acid hydrolysis via HPLC.[ncbi.nlm.nih.gov] At the end of intervention, levels of benzoic (median 1782 vs 4156), protocatechuic (709 vs 2417), vanillic (2779 vs 4753), 3-hydroxycinnamic (143 vs 351), p-coumaric (182[ncbi.nlm.nih.gov] With regard to the inhibitory effect on human platelet aggregation, methyl caffeate, 3,4-di-O-caffeoylquinic acid and methyl 3,4-di-O-caffeoylquinate had a strong effect.[ncbi.nlm.nih.gov] Based on methylation analysis, partial acid hydrolysis, and NMR spectra, the polysaccharide was elucidated to be a rhamnogalacturonan backbone and substituted partly at C-[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Probenecid

    His uric acid was 11 mg/dL despite maximal dosing of febuxostat. He had previously failed pegloticase infusions as well.[ncbi.nlm.nih.gov] Other names: Benzoic acid, 4-[(dipropylamino)sulfonyl]-; Benzoic acid, p-(dipropylsulfamoyl)-; p-(Dipropylsulfamoyl)benzoic acid; p-(Dipropylsulfamyl)benzoic acid; Apurina[webbook.nist.gov] Chemical products with special stability considerations: Esters Ester compounds include the following: • Succinimidyl esters (SE, also known as NHS esters), such as our amine-reactive[biotium.com] Concentrations of cilostazol and its metabolites OPC-13015 [6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-2(1H)-quinolinone] and OPC-13213 [3,4-dihydro-6-[4-[1-(trans-4-hydroxycyclohexyl[ncbi.nlm.nih.gov] […] uric acid reabsorption.[ncbi.nlm.nih.gov] Here, we describe a new inhibitor of bitter taste receptors, p-(dipropylsulfamoyl)benzoic acid (probenecid), that acts on a subset of TAS2Rs and inhibits through a novel,[ncbi.nlm.nih.gov] As the fluorescent dye is transferred into the cell, the AM ester portion of the dye is removed by cellular esterases.[thermofisher.com]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Escherichia Coli

    An antimicrobial effect of benzoic acid (BA) and ethylenediaminetetraacetic acid (EDTA) was evaluated as a potential antimicrobial treatment against Escherichia coli O157:[ncbi.nlm.nih.gov] Structural modifications of the macrocyclic ring, the peptide sequence and the lipophilic tail led us to 14 novel macrocyclic boronic esters.[ncbi.nlm.nih.gov] Deoxyribonucleic acid sodium salt from Escherichia coli strain B has been used for: • PCR reactions of genomic DNA of Gardnerella vaginalis • nick translation and radiolabeling[sigmaaldrich.com] Results are the averages of two experiments SEM. ( C ) NMR spectra of Mosher’s ester derivatized AG.[pnas.org] An antimicrobial effect of benzoic acid (BA) and ethylenediaminetetraacetic acid (EDTA) was evaluated as a potential antimicrobial treatment against Escherichia coli O157:[ncbi.nlm.nih.gov] In the light of steadily increasing rates of antimicrobial resistance, we have developed novel macrocyclic lipopeptides, linking P2 and P1' by a boronic ester warhead, capable[ncbi.nlm.nih.gov] Samples were converted into their corresponding Mosher’s ester and analyzed by 1 H- and 19 F-NMR ( 34 ).[pnas.org]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Lidocaine

    BACKGROUND: Injectable fillers, such as those containing hyaluronic acid (HA), are increasingly used to smooth age-related facial creases and wrinkles.[ncbi.nlm.nih.gov] Development and validation of an HPLC- DAD method for simultaneous determination of cocaine, benzoic acid, benzoylecgonine and the main adulterants found in products based[caymanchem.com] In contrast to the local anesthetics of the ester group, the ones of the amide group (for example prilocaine and lidocaine) are considered to be rare sensitizers.[ncbi.nlm.nih.gov] Abstract BACKGROUND: The use of blunt-tipped microcannulas for injection of hyaluronic acid (HA) filler in the lip and perioral area has gained popularity as they provide[ncbi.nlm.nih.gov] BACKGROUND: Hyaluronic acid (HA) dermal fillers are frequently used to correct or smooth facial wrinkles and folds such as nasolabial folds.[ncbi.nlm.nih.gov] […] safety and effectiveness associated with the use of a blunt-tipped microcannula for lip augmentation and correction of perioral rhytids using a small-particle, hyaluronic acid[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl
  • Clofibrate

    Also in common to both enzymes is the ability to metabolize fatty acids such as laurate and arachidonic acid.[ncbi.nlm.nih.gov] It is concluded that benzoic acid and clofibrate are not estrogenic in the assays used here.[ncbi.nlm.nih.gov] Abstract Etofibrate (I), the ethylene glycol diester of clofibric and nicotinic acids, degrades almost equally through both half-esters with half-lives of approximately 10[ncbi.nlm.nih.gov] DOI: 10.1126/science.1198095 Abstract Two hypolipidemic compounds [ 4-chloro-6(2,3-xylidino)-2-pyrimidinyl-thio] acetic acid, and 2-chloro-5(3,5-dimethylpiperidinosufony)benzoic[science.sciencemag.org] We found a decrease in the mass concentration of cholesteryl ester transfer protein (P 0.05).[ncbi.nlm.nih.gov] […] acid, ethyl ester Generator alpha-(P-Chlorophenoxy)isobutyrate, ethyl ester Generator α-(P-chlorophenoxy)isobutyrate, ethyl ester Generator α-(P-chlorophenoxy)isobutyric[hmdb.ca] Abstract Aqueous or methanolic solutions of clofibrate and clofibric acid are photolabile towards UVB light under aerobic as well as anaerobic conditions.[ncbi.nlm.nih.gov]

    Missing: 3 ((3 (ethoxymethyl) 5 fluoro 3 6 dihydro 2 6 dioxo 1(2H) pyrimidinyl)carbonyl) 6 (benzoyloxy) 3 cyano 2 pyridinyl