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153 Possible Causes for 3-4 Hz Spikes, 'Eye of the Tiger' Sign on MRI, Jerk-Locked Premyoclonus Spikes

  • Benign Adult Familial Myoclonic Epilepsy

    T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] […] cortical spikes detected by the jerk-locked back-averaging) ( Ikeda et al., 1990 ).[academic.oup.com] Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4-Hz spike and multispike-slow wave complexes: linkage to chromosome 8q24.[reference.medscape.com]

  • Generalized Clonic or Tonic-Clonic Seizures

    premyoclonus spikes Hand tremor Neuronal loss in central nervous system Cutaneous photosensitivity Hyperreflexia Heterogeneous Weight loss Dystonia Splenomegaly Thrombocytopenia[mendelian.co] The EEG shows generalised spike and wave discharges of 3 to 4 Hz and some with photic sensitivity. This is potentially a lifelong epilepsy.[pennsw.com.au] […] callosum Muscular hypotonia Infantile onset Intellectual disability, moderate Intention tremor Progressive neurologic deterioration Absence seizures Nevus EEG abnormality Jerk-locked[mendelian.co]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Epilepsy

    […] to 8 years of age, in an otherwise apparently healthy child. 3 The classic electroencephalogram (EEG) shows generalized spike-wave bursts (of 3 Hz) with normal background[doi.org] Hz Spike and Wave Discharges, Epilepsia, 31, 5, (557-566), (2007).[doi.org] […] childhood-onset epilepsy, making it the most common form of pediatric epilepsy. 1,2 The syndrome is characterized by daily frequent but brief staring spells, typically beginning at 4[doi.org]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Absence Seizure

    In electroencephalography (EEG), generalized 3-4 Hz spike and slow wave complexes indicate an absence seizure.[symptoma.com] Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4-Hz spike and multispike-slow wave complexes: linkage to chromosome 8q24.[emedicine.com] 4 Hz spike-and-slow-wave complexes on EEG. [6] In childhood absence epilepsy, seizures are frequent and brief, lasting just a few seconds (pyknoleptic).[emedicine.com]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Juvenile Myoclonic Epilepsy

    Interictal electroencephalography (EEG) in JME shows interictal epileptiform discharges such as generalized spikes, polyspikes, bilateral-synchronous 4-6/s spike-wave complexes[go.galegroup.com] Myoclonic jerks appear to be time-locked to generalized 3-5 Hz spike-and wave complexes [8]. Photoparoxysmal response was seen in 40% of patients.[go.galegroup.com]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Idiopathic Generalized Epilepsy

    4 Hz spikes and waves in all regions of the brain 1 st -line : valproic acid Avoid triggers : sleep deprivation, alcohol, drugs, flickering lights 60% are seizure -free under[amboss.com] Her EEG showed 34 Hz spike and wave discharges. She had a daughter with childhood absence epilepsy, and two sisters and a cousin with seizures (fig 2 , family 1).[jnnp.bmj.com] The EEG usually shows asymptomatic 3 to 4 Hz generalized spike/polyspike discharges, but often video-EEG after partial sleep deprivation with recording in sleep and awakening[medlink.com]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Myoclonic-Astatic Epilepsy

    […] presence of generalized spike- or polyspike-wave EEG discharges at 2-3 Hz, without focal spike discharges; and (4) exclusion of severe and benign myoclonic epilepsy (SME,[ncbi.nlm.nih.gov] EEG shows regular and irregular bilaterally synchronous 2- to 3-Hz spike-waves and polyspike patterns with a 4- to 7-Hz background. 84% of affected children show normal development[ipfs.io] […] before onset of epilepsy and absence of organic cerebral abnormalities; (2) onset of myoclonic, myoclonic-astatic or astatic seizures between 7 months and 6 years of age; (3)[ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Childhood Absence Epilepsy

    Childhood absence epilepsy with tonic–clonic seizures and electroencephalogram 34Hz spike and multispike–slow wave complexes: linkage to chromosome 8q24.[doi.org] […] consist of behavioral arrest with or without automatisms, usually last 30-60 seconds, and demonstrate a characteristic 3-Hz generalized spike-wave (GSW) pattern on EEG, often[ncbi.nlm.nih.gov] ., 1977) or bicuculline (Steriade and Contreras, 1998) led to 3-4 Hz oscillations with no sign of spike-and-wave discharge.[scholarpedia.org]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Juvenile Absence Epilepsy

    Diagnostic methods Diagnosis relies on the clinical features and on electroencephalogram (EEG) recorded awake and during sleep, that displays a generalized 3-4 Hz spike-and-slow-wave[orpha.net] Generalized 3-4 Hz spike or polyspike slow-wave complexes. Neuro Imaging: Not usually required. Mainly from other IGEs such as CAE or Juvenile Myoclonic Epilepsy (JME).[pennsw.com.au] Childhood absence epilepsy with tonicclonic seizures and electroencephalogram 3-4-Hz spike and multispikeslow wave complexes: linkage to chromosome 8q24.[books.google.es]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • West Syndrome

    2015 ICD-9-CM Diagnosis Code 345.6 Infantile spasms There are 2 ICD-9-CM codes below 345.6 that define this diagnosis in greater detail. Do not use this code on a reimbursement claim. Clinical Information A rare autosomal recessive inherited neurodegenerative disorder caused by mutations in the pla2g6 gene. It is[…][icd9data.com]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes

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