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419 Possible Causes for 3-4 Hz Spikes, Generalized Spike-and-Slow-Waves, Urine Organic Acids Abnormal

  • West Syndrome

    Lennox-Gastaut Syndrome: LGS is characterized by multiple types of seizures and an abnormal EEG with generalized slow spikewave discharges.[cdkl5.com] Urine organic acids, amino acids and serum biotinidase are done. CT or MRI scan of the brain is done before the treatment is started.[epainassist.com] Interictal EEG displays diffuse and asynchronous high voltage spikes and slow waves suggesting the hypsarrhythmic pattern. B.[bmcneurol.biomedcentral.com]

  • Epilepsy

    Electroencephalography (EEG) showed progressively slowed background activity and sporadic generalized spike-and-wave discharges.[ncbi.nlm.nih.gov] […] to 8 years of age, in an otherwise apparently healthy child. 3 The classic electroencephalogram (EEG) shows generalized spike-wave bursts (of 3 Hz) with normal background[doi.org] Neuroimaging studies were unremarkable and electroencephalograms showed high voltage 200-400uV, 2-2.5 Hz generalized spike-and-waves and polyspikes with alternating frontal[ncbi.nlm.nih.gov]

    Missing: Urine Organic Acids Abnormal
  • Juvenile Absence Epilepsy

    All patients had minimum twice EEG recordings and all had typical 3-Hz generalized spike and slow-wave discharges at least on one EEG.[ncbi.nlm.nih.gov] Diagnostic methods Diagnosis relies on the clinical features and on electroencephalogram (EEG) recorded awake and during sleep, that displays a generalized 3-4 Hz spike-and-slow-wave[orpha.net] EEG shows classical generalized 3 Hz spike-and-slow-wave discharges.[medlink.com]

    Missing: Urine Organic Acids Abnormal
  • Benign Adult Familial Myoclonic Epilepsy

    , high-amplitude spike and slow-wave complexes 3.5 Hz, typically 4 s duration.  Absence seizures in JAE are more sporadic.  EEG is slightly faster with generalized spike[slideshare.net] Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4-Hz spike and multispike-slow wave complexes: linkage to chromosome 8q24.[reference.medscape.com] Her EEG showed 34 Hz spike and wave discharges. She had a daughter with childhood absence epilepsy, and two sisters and a cousin with seizures (fig 2 , family 1).[jnnp.bmj.com]

    Missing: Urine Organic Acids Abnormal
  • Generalized Clonic or Tonic-Clonic Seizures

    , poly spike discharges." [2] The clonic phase EEG will show "high amplitude activity that is typically interrrupted by slow waves to create a spike-and-slow-wave pattern.[en.wikipedia.org] The EEG shows generalised spike and wave discharges of 3 to 4 Hz and some with photic sensitivity. This is potentially a lifelong epilepsy.[pennsw.com.au] According to "Harrisons Manual of Medicine," the EEG during the tonic phase will show a "progressive increase in low-voltage fast wave activity, followed by generalized high-amplitude[en.wikipedia.org]

    Missing: Urine Organic Acids Abnormal
  • Juvenile Myoclonic Epilepsy

    […] multiple spike and spike slow wave discharges (in an untreated patient).8 The possible factors responsible for the delay in the diagnosis of JME were studied retrospectively[neurologyindia.com] Interictal electroencephalography (EEG) in JME shows interictal epileptiform discharges such as generalized spikes, polyspikes, bilateral-synchronous 4-6/s spike-wave complexes[go.galegroup.com] slow wave discharges.[en.wikipedia.org]

    Missing: Urine Organic Acids Abnormal
  • Myoclonic-Astatic Epilepsy

    The interictal EEG revealed frequent bursts of generalized 100-200 μV, 2-4 Hz spike-and-slow-wave complexes.[ncbi.nlm.nih.gov] […] presence of generalized spike- or polyspike-wave EEG discharges at 2-3 Hz, without focal spike discharges; and (4) exclusion of severe and benign myoclonic epilepsy (SME,[ncbi.nlm.nih.gov] EEG shows regular and irregular bilaterally synchronous 2- to 3-Hz spike-waves and polyspike patterns with a 4- to 7-Hz background. 84% of affected children show normal development[ipfs.io]

    Missing: Urine Organic Acids Abnormal
  • Idiopathic Generalized Epilepsy

    […] epilepsy K complex lambda mu OIRDA PLEDs phantom spike and wave photic driving photoparoxysmal response photomyogenic artifact poly spike and wave posterior dominant rhythm[eegatlas-online.com] 4 Hz spikes and waves in all regions of the brain 1 st -line : valproic acid Avoid triggers : sleep deprivation, alcohol, drugs, flickering lights 60% are seizure -free under[amboss.com] Her EEG showed 34 Hz spike and wave discharges. She had a daughter with childhood absence epilepsy, and two sisters and a cousin with seizures (fig 2 , family 1).[jnnp.bmj.com]

    Missing: Urine Organic Acids Abnormal
  • Encephalopathy

    […] delta bursts, that is called as paradoxical arousal response 18. * Background slowing * Increased theta delta activity * Paroxysmal sharp waves * Theta bursts * Delta bursts[slideshare.net] * Spike discharges *Triphasic waves * FIRDA * OIRDA * TIRDA * Alpha / theta coma Periodic pattern Spindle coma ECS 19.[slideshare.net] *Seen in Anoxic brain damage, CNS supressant drugs and severe hypothermia *Paradoxical arousal response *A stimulus brings out slower activity with generalized high voltage[slideshare.net]

    Missing: Urine Organic Acids Abnormal
  • Lennox-Gastaut Syndrome

    The semiology of seizures progressively changed to generalized episodes of hypertonia and myoclonus, with slow spike-wave electroencephalographic activity.[ncbi.nlm.nih.gov] Hz theta and G PSW Rarely M Dravet/SIME Febrile, other seizures at 2–3 years Slow with irregular spike wave Rare Rare Yes M AA GTC Focal West Usually Hypsarrhythmia Yes Yes[onlinelibrary.wiley.com] Lennox-Gastaut syndrome (LGS) is a childhood epileptic encephalopathy characterized by an electroclinical triad of generalized slow spike wave (SSW) activity in the EEG, multiple[ncbi.nlm.nih.gov]

    Missing: Urine Organic Acids Abnormal

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