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832 Possible Causes for 3-4 Hz Spikes, Myoclonic Jerking, Onset of Disease between 25 and 40 Years of Age

  • Benign Adult Familial Myoclonic Epilepsy

    By the jerk-locked averaging method, a positive spike time-locked to the myoclonic jerk was demonstrated in four patients before 15-20 msec of myoclonic jerk.[ci.nii.ac.jp] Celiac disease (or gluten sensitive enteropathy): The age of onset may vary between 40 - 80 years and the mean duration of ataxia between 3 to 25 years.[neuroweb.us] Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4-Hz spike and multispike-slow wave complexes: linkage to chromosome 8q24.[reference.medscape.com]

  • Absence Seizure

    […] seizures), and juvenile myoclonic epilepsy (JME; generalised syndrome characterised by myoclonic jerks, generalised tonic-clonic seizures, and, less commonly, absence seizures[bestpractice.bmj.com] In electroencephalography (EEG), generalized 3-4 Hz spike and slow wave complexes indicate an absence seizure.[symptoma.com] Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4-Hz spike and multispike-slow wave complexes: linkage to chromosome 8q24.[emedicine.medscape.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Juvenile Myoclonic Epilepsy

    The myoclonic jerks occur rarely in EMA. They are usually mild and are freqently restricted to the upper extremities.[ncbi.nlm.nih.gov] Interictal electroencephalography (EEG) in JME shows interictal epileptiform discharges such as generalized spikes, polyspikes, bilateral-synchronous 4-6/s spike-wave complexes[go.galegroup.com] All of these patients were contacted and asked specifically about myoclonic jerks.[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Epilepsy

    So the jerks were considered as cortical origin and generalized myoclonic seizure was confirmed.[ncbi.nlm.nih.gov] […] to 8 years of age, in an otherwise apparently healthy child. 3 The classic electroencephalogram (EEG) shows generalized spike-wave bursts (of 3 Hz) with normal background[doi.org] Hz Spike and Wave Discharges, Epilepsia, 31, 5, (557-566), (2007).[doi.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Myoclonic-Astatic Epilepsy

    The involvement of these structures might predispose to the typical seizure semiology of myoclonic jerks observed in MAE.[ncbi.nlm.nih.gov] […] presence of generalized spike- or polyspike-wave EEG discharges at 2-3 Hz, without focal spike discharges; and (4) exclusion of severe and benign myoclonic epilepsy (SME,[ncbi.nlm.nih.gov] jerks, by using burst-locked EEG averaging where necessary.[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Idiopathic Generalized Epilepsy

    Myoclonic-astatic seizures consist of symmetric myoclonic jerks followed by periods of absent muscle tone that can result in falls.[symptoma.com] 4 Hz spikes and waves in all regions of the brain 1 st -line : valproic acid Avoid triggers : sleep deprivation, alcohol, drugs, flickering lights 60% are seizure -free under[amboss.com] Her EEG showed 34 Hz spike and wave discharges. She had a daughter with childhood absence epilepsy, and two sisters and a cousin with seizures (fig 2 , family 1).[jnnp.bmj.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Juvenile Absence Epilepsy

    A total of 33 patients (47%) also had myoclonic jerks with a mean age at onset of 16 years.[medlink.com] Diagnostic methods Diagnosis relies on the clinical features and on electroencephalogram (EEG) recorded awake and during sleep, that displays a generalized 3-4 Hz spike-and-slow-wave[orpha.net] Generalized 3-4 Hz spike or polyspike slow-wave complexes. Neuro Imaging: Not usually required. Mainly from other IGEs such as CAE or Juvenile Myoclonic Epilepsy (JME).[pennsw.com.au]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Generalized Clonic or Tonic-Clonic Seizures

    myoclonic jerks of cortical origin.[mendelian.co] The EEG shows generalised spike and wave discharges of 3 to 4 Hz and some with photic sensitivity. This is potentially a lifelong epilepsy.[pennsw.com.au] Generalized myoclonic-tonic-clonic seizures begin with a few myoclonic jerks followed by tonic-clonic activity.[medlink.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Lennox-Gastaut Syndrome

    In such cases, massive myoclonic jerks, myoclonic-atonic attacks, as well as atonic seizures may occur, though much less frequent and severe than the other manifestations.[epilepsyontario.org] Hz theta and G PSW Rarely M Dravet/SIME Febrile, other seizures at 2–3 years Slow with irregular spike wave Rare Rare Yes M AA GTC Focal West Usually Hypsarrhythmia Yes Yes[onlinelibrary.wiley.com] Lennox and Davis first correlated the slow spike-and-wave EEG pattern with a distinctive group of clinical manifestations including specific seizure types (myoclonic jerks[medlink.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Early Infantile Epileptic Encephalopathy Type 3

    Both patients had early infantile seizures characterized by fragmentary myoclonic jerks associated with burst-suppression pattern on electroencephalography.[ncbi.nlm.nih.gov] Early Myoclonic Encephalopathy starts in the first 10 days of an infant’s life with erratic small jerks (i.e. myoclonic seizures).[seizuresinfant.com] […] epileptic encephalopathy which began between two days and ten weeks of life. at onset it is associated with: myoclonic jerks, partial fits and periodic paroxysmal EEG abnormalities[semanticscholar.org]

    Missing: Onset of Disease between 25 and 40 Years of Age

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