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18 Possible Causes for 3 hydroxymorphinan

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  • Naloxiphan

    Chemical Name: Levallorphan Chemical Formula: C 19 H 25 NO CAS Number: 152-02-3 Synonyms: Morphinan-3-ol, 17-(2-propenyl)-;Morphinan-3-ol, 17-allyl-;L-N-allyl-3-hydroxymorphinan[caslab.com] (1:1); 11-Allyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-iminoethanophenanthren-6-ol Tartrate; N-Allyl-3-hydroxymorphinan Tartrate; 17-(2-Propenyl)-morphinan-3-ol [R-(R*,R*)]-2,3[trc-canada.com] , 17-(2-propenyl)- Morphinan-3-ol, 17-allyl- N-Allyl-3-hydroxymorphinan Naloxiphan Ro-1-7700 UNII-353613BU4U Systematic Names Morphinan-3-ol, 17-(2-propenyl)- Morphinan-3-[chem.nlm.nih.gov]

  • Dextromethorphan

    In humans, DXM is metabolized to dextrorphan (DXO), as well as 3-methoxymorphinan (MEM) and 3-hydroxymorphinan (HYM).[dmd.aspetjournals.org] Blood and urine were collected over 168 hours and assayed for dextromethorphan, total (conjugated and unconjugated) dextrorphan, 3-methoxymorphinan, and total 3-hydroxymorphinan[ncbi.nlm.nih.gov] Abbreviations used are:: DXM dextromethorphan DXO dextrorphan MEM 3-methoxymorphinan HYM 3-hydroxymorphinan P450 cytochrome P-450 HPLC high-pressure liquid chromatography[dmd.aspetjournals.org]

  • Levorphanol

    List of Suppliers Complete supplier list of Levorphanol Identification Name Levorphanol Synonyms (-)-N-Methylmorphinan-3-ol; Aromarone; Levorphan; Levorphanol; N-Methyl-3-[chemblink.com] CAS No. 77-07-6 Chemical Name: levorphanol Synonyms C08014;Levorphan;Aromarone;Ro 1-5431;l-Levorphanol;Levorphanol-d3;N-Methyl-3-hydroxymorphinan;MORPHINAN-3-OL,17-METHYL-[chemicalbook.com] hydroxymorphinan DrugCentral racemorphan DrugCentral 77-07-6 CAS Registry Number KEGG COMPOUND[ebi.ac.uk]

  • Hallucinogen

    The other pathway goes to 3-methoxymorphinan first (via P450-3A4 and P450-3A5), and then to 3-hydroxymorphinan.[erowid.org] DXM is metabolized via two pathways, both of which lead to the same thing, 3-hydroxymorphinan (3HM).[erowid.org] After being converted to DXO, the enzymes P450-3A4 and P450-3A5 convert DXO to 3-hydroxymorphinan ( 77 ).[erowid.org]

  • Clozapine

    Psychiatr Res 117:85–88 CrossRef Google Scholar Zhang W, Shin EJ, Wang T, Lee PH, Pang H, Wie MB, Kim WK, Kim SJ, Huang WH, Wang Y, Zhang W, Hong JS, Kim HC (2006) 3-Hydroxymorphinan[doi.org] Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.[ncbi.nlm.nih.gov] ; 5 :21. [ PMC free article ] [ PubMed ] [ Google Scholar ] Zhang W, Shin EJ, Wang T, Lee PH, Pang H, Wie MB, Kim WK, Kim SJ, Huang WH, Wang Y, Zhang W, Hong JS, Kim HC. 3-[ncbi.nlm.nih.gov]

  • Intoxication

    Moreover, 3-hydroxymorphinan is obtained through N - and O -didemethylation by CYP3A4 and CYP2D6, respectively.[nejm.org] In humans, dextromethorphan is metabolized into dextrorphan by CYP2D6 and into 3-methoxymorphinan, mainly by CYP3A4.[nejm.org]

  • Oxycodone

    Moreover, 3-hydroxymorphinan is obtained through N - and O -didemethylation by CYP3A4 and CYP2D6, respectively.[doi.org] (l–3hydroxymorphinan) (7) Phenomorphan (3–hydroxy–17–(2–phenylethyl)morphinan) (8) Racemethorphan (d,1–3–methoxy–17–methylmorphinan) (9) Racemorphan (d,l–3–hydroxy–N–methylmorphinan[en.wikibooks.org] 1,1–dimethylethyl)–4,5–epoxy–18,19–dihydro–3–hydroxy–6–methoxy–α–methyl–6,14–ethenomorphinan–7–methanol) (2) Drotebanol (6ß,14–dihydroxy–3,4–dimethoxy–17–methylmorphinan) (3)[criminalnotebook.ca]

  • Codeine

    Moreover, 3-hydroxymorphinan is obtained through N - and O -didemethylation by CYP3A4 and CYP2D6, respectively.[doi.org] In humans, dextromethorphan is metabolized into dextrorphan by CYP2D6 and into 3-methoxymorphinan, mainly by CYP3A4.[doi.org]

  • Lysergic Acid Diethylamide Poisoning

    […] methoxy-17-methylmorphinan) Levorphanol (l-3-hydroxy-17-methylmorphinan) Levophenacylmorphan (l-3-hydroxy-17-phenacylmorphinan) Norlevorphanol (l-3-hydroxymorphinan) Phenomorphan[en.wikipedia.org] (3-hydroxy-17-(2-phenylethyl)morphinan) Race methorphan (d,1-3-methoxy-17-methylmorphinan) Racemorphan (d,l-3-hydroxy-N-methylmorphinan)but not including: Dextromethorphan[en.wikipedia.org] […] dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol) Drotebanol (6β,14-dihydroxy-3,4-dimethoxy-17-methylmorphinan) Levomethorphan (l-3-[en.wikipedia.org]

  • Fentanyl

    […] methoxy–17–methylmorphinan) Levorphanol (l–3–hydroxy–17–methylmorphinan) Levophenacylmorphan (l–3–hydroxy–17–phenacylmorphinan) Norlevorphanol (l–3hydroxymorphinan) Phenomorphan[laws.justice.gc.ca] (3–hydroxy–17–(2–phenylethyl)morphinan) Racemethorphan (d,1–3–methoxy–17–methylmorphinan) Racemorphan ( d,l –3–hydroxy–N–methylmorphinan) but not including Dextromethorphan[laws.justice.gc.ca] […] dimethylethyl)–4,5–epoxy–18,19–dihydro–3–hydroxy–6–methoxy–α–methyl–6,14–ethenomorphinan–7–methanol) Drotebanol (6ß,14–dihydroxy–3,4–dimethoxy–17–methylmorphinan) Levomethorphan (l–3[laws.justice.gc.ca]

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