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29 Possible Causes for 3 hydroxyphenylacetate, degradation

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  • Tyrosine Transaminase Deficiency

    3-monooxygenase [EC: ] K16901 anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase [EC: ] K00484 flavin reductase (NADH[] : Homocystiene FH4 B12 - Methionine Degradation: Methionine - SAM - SAH - Homocystiene Synthesis: Methionine - SAM - SAH - Homocystiene Degradation: Homocystiene FH4 B12 -[] PATHWAY: Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 2/6. SUBUNIT: Homodimer (Probable).[]

  • Familial Dysautonomia

    […] methoxy-4-hydroxyphenylacetic acid (HVA), 3-methoxytyrosine, and respective conjugates, etc.[] We observed a significant lower expression of both IKBKAP transcript and IKAP/hELP1 protein in FD cells resulting from the degradation of the transcript isoform skipping exon[] A rational strategy for FD treatment could be to identify drugs increasing IKAP/hELP1 expression levels by blocking protein degradation pathways such as the 26S proteasome[]

  • Lysinuric Protein Intolerance

    Furthermore, of these metabolites, myo-inositol, threonic acid, 2,5-furandicarboxylic acid, galactaric acid, 4-hydroxyphenylacetic acid, indole-3-acetic acid and beta-aminoisobutyric[] A decrease in the platelet count and an increase in the plasma levels of thrombin-antithrombin III complex (TAT) and fibrin degradation products (FDPs) indicated the presence[] SP-D was partially degraded and entrapped in the unusual surfactant lipid tubules with circular lattice, in vivo.[]

  • Bismuth Subsalicylate

    […] l -tyrosine, phenylacetate, 3-hydroxyphenylacetate, 4-hydroxyphenylacetate, and phenylpropionate.[] After oral administration, bismuth subsalicylate is degraded in the stomach to produce salicylic acid.[] We did not find previously published descriptions of salicylate degradation by fusaria.[]

  • Phenelzine

    ), tryptamine (T), 5-hydroxytryptamine (5-HT), 5-hydroxyindoleacetic acid (5-HIAA), normetanephrine (NME), 3-methoxy-4-hydroxyphenylglycol (MHPG), 3-methoxytyramine (3-MT)[] Abstract The ability of the therapeutic agents phenelzine (PZ) and hydralazine (HD) to stimulate the rate of protein degradation and H2O2 production in human red blood cells[] These results confirm that PZ is capable of protecting mitochondrial function and providing neuroprotection after experimental TBI related to scavenging of neurotoxic LP degradation[]

  • Dehydroepiandrosterone

    The brain levels of monoamines and their metabolites, including norepinephrine, serotonin, 5-hydroxy-3-indolacetic acid, dopamine, and 3,4-hydroxyphenylacetic acid, were analyzed[] 288.4244 Structure Remark Same as: D08409 Reaction R01837 R03404 R03405 R03406 R03407 R03408 R08517 R08961 R09957 Pathway map00140 Steroid hormone biosynthesis map00984 Steroid degradation[] […] delta-isomerase activity Specific Function Catalyzes the oxidation and isomerization of cholesterol to cholestenone (4-cholesten-3-one), which is an initial step in the cholesterol degradation[]

  • Tiludronate

    O-FORMAMIDO-ALPHA-D-MANNOPYRANOSIDE non-polymer 0 0M 3GA 3-PIPERIDYL-N-GUANIDINO-L-ALANINE non-polymer 0 0M 3HB 3-HYDROXYBENZOIC ACID non-polymer 0 0M 3HP 3-HYDROXYPHENYLACETATE[] […] cross-linked carboxyterminal telopeptides of type I collagen (ICTP), urinary hydroxyproline/creatinine (Hyp/Cr), pyridinoline/Cr (Pyr/Cr), and alpha-1 collagen chain products degradation[] […] non-polymer 0 0M 3IB 3-INDOLEBUTYRIC ACID non-polymer 0 0M 3IN N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[ non-polymer 0 0M 3MA 6-AMINO-3-METHYLPURINE non-polymer 0[]

  • Gamma Hydroxybutyrate

    hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands KR20090009241A ( ko ) 2006-05-18 2009-01-22 니폰 가야꾸 가부시끼가이샤 포도필로톡신류의 고분자 결합체 CN101678043A ([] The goal of the current study was to examine GHB metabolism in mice with targeted ablation of the GABA degradative enzyme succinic semialdehyde dehydrogenase (SSADH(-/-) mice[] Drugs and endogenous substances that can inhibit GHB dehydrogenase include barbiturates, valproic acid, salicylate, valproic acid, blood ketones, and phenylalanine degradation[]

  • Rofecoxib

    841861" "822184 Tween 20","product/Tween-20,MDA_CHEM-822184" "841378 α-Benzoin oxime","product/%CE%B1-Benzoin-oxime,MDA_CHEM-841378" "814143 (S)-(-)-1-Benzoyloxy-2-benzyloxy- 3-[] […] reacts with the aldehyde group of allysine in elastin to give a condensation covalent adduct, thereby preventing the formation of cross-linkages in the elastin and causing degradation[] Carboxybutyltriphenylphosphonium-bromide,MDA_CHEM-818330" "800889 Methyl formate","product/Methyl-formate,MDA_CHEM-800889" "841861 Methyl 4-hydroxyphenylacetate","product/Methyl-4-hydroxyphenylacetate[]

  • Organic Aciduria

    The organic acids most often detected in urine were lactic, 4-hydroxyphenylacetic and 3-hydroxybutyric acids.[] […] is defective in the leucine degradative pathway.IncidenceWhile each individual disorder is rare, overall incidence of organic acidemias is 1:20, 000.[] , phenylpyruvic acid, 2-hydroxyphenylacetic acid 2-Oxoadipic aciduria 2-Oxoadipic acid, 2-hydroxyadipic acid 3-Hydroxy-3-methylglutaric aciduria 3-Hydroxy-3-methylglutaric[]

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