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50 Possible Causes for 3 hydroxypropionate, pathway

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  • Low Protein Diet

    […] of AAR pathway-related genes.[] The urine of the present case contained 2-methylcitric acid, 3-hydroxypropionic acid, N-propionylglycine, 2-hydroxy-3-methylbutyric acid, N-tiglylglycine, 3-hydroxyvaleric[] Importantly, activation of autophagy pathways in utero restored β cell function in offspring from low-diet fed mothers.[]

  • Biotin Deficiency

    Collectively, these findings are consistent with activation of survival pathways in biotin-deficient lymphoma cells.[] Mean 3-hydroxypropionic acid excretion rates remained normal during biotin depletion in both studies.[] Abnormalities in particular fatty acids in the omega 6, omega 3 and omega 9 pathways were also found, but these abnormalities did not resolve with biotin therapy.[]

  • Biotinidase Deficiency

    […] biotin results in pronounced, rapid, clinical and biochemical improvement, but some patients have residual neurological damage comprising neurosensory hearing loss, visual pathway[] 3.1 mumol/L), elevated 3-methylcrontonylglycine, methylcitrate and 3-hydroxypropionate in urine and very low biotinidase activities. (2) These patients have been treated[] Defects in these pathways cause severe metabolic disorder in the body. In general, biotinidase deficiency can be classified into two levels: partial and profound.[]

  • Primary Hyperoxaluria

    They resulted in the understanding that many mutations cause AGT deficiency by affecting the folding pathway of the protein leading to a reduced expression level, an increased[] , 3-hydroxypropionic acid and 2-ethyl-3-hydroxypropionic acids were observed in increased amounts in the urine.[] Proline dehydrogenase 2 (PRODH2), historically known as hydroxyproline oxidase, is the first step in the hydroxyproline catabolic pathway and represents a drug target to reduce[]

  • Propionic Acidemia

    Homocitrullinuria, presence of epsilon-N-acetyl-l-lysine in urine, and absence of saccharopine indicate deficiency of the saccharopine pathway of lysine degradation.[] Thus, we aimed to develop a multiplex approach for concurrent determination of 3-hydroxypropionic acid, methylmalonic acid and methylcitric acid from the same dried blood[] The results show an increase in intracellular ROS content compared to controls, correlating with the activation of the JNK and p38 signaling pathways.[]

  • Multiple Carboxylase Deficiency

    Within sections each chapter deals with an individual disease, starting with a useful summary of major phenotypic expression and including clear and helpful biochemical pathways[] The early form showed higher urinary excretion of 3-hydroxyisovalerate and 3-hydroxypropionate than the late form and was associated with normal plasma biotin concentrations[] AJ, JR. (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in Ataxia-Telangiectasia. ‏ الصفحة 136 - R. (1997).[]

  • Deficiency of Glycerol Kinase

    ), or is completely oxidized through glycolytic pathway.[] However, there has been no report of controlling the metabolic flux using substrates other than glucose, such as xylose or glycerol. 3-Hydroxypropionic acid (3-HP) is a three[] This molecule can then enter the metabolic pathway of glycloysis and provide more energy for the cell. [8] Looking at the entire glycolysis pathway this conversion would yield[]

  • Eubacterium

    Several of the genes in this operon have been shown to catalyze specific reactions in the 7alpha-dehydroxylation pathway.[] As after growth of E. hallii in the presence of glycerol, no peaks at the rention times of the 3-hydroxypropionate standard appeared, it was assumed that 3-hydroxypropionate[] The observed intermediates of quercetin and luteolin conversion suggest that the degradation pathways in E. ramulus start with an analogous reduction step followed by different[]

  • Methanobacterium Extroquens

    Fig. 2 Hypothesized methanol metabolism pathways in D. kuznetsovii .[] The disclosure provides that a bacterial cell is genetically modified to produce 3-hydroxypropionate, such as by including exogenous DNA encoding genes to produce 3-hydroxypropionate[] […] acid (TCA) cycle, anaplerotic pathways, gluconeogenesis, pentose-phosphate pathway (PPP), and Entner-Doudoroff (ED) pathway (Figure 1 ).[]

  • Hyperglycinuria

    The activity of the glycine cleavage system, the major catabolic pathway of glycine, in liver homogenates from rats treated with valproic acid was clearly reduced.[] Holocarboxylase synthetase deficiency X ---3-Hydroxyisovaleric acid X X X ---3-Methylcrotonylglycine X X X ---Methylcitric acid X X ---3-Hydroxypropionic acid X X X ---*Lactic[] Click the image above or here to open this pathway in the Pathway Browser SLC36A2 encodes proton-coupled amino acid transporter 2 (PAT2), a high-affinity cotransporter of[]

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