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11,194 Possible Causes for 3HAP, activity, mutase

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  • Schistosoma Japonicum

    Recombinant phosphoglycerate mutase (PGM) and UV excision repair protein RAD23 homolog B (RAD23) proteins were expressed and their diagnostic potential for schistosomiasis[ncbi.nlm.nih.gov] The induction of senescence of HSCs would accelerate the clearance of the activated HSCs.[ncbi.nlm.nih.gov] Therefore, Sj enolase can be used to indicate active Schistosoma infection, and detecting serum Sj enolase is important for diagnosis and evaluating treatment effect.[ncbi.nlm.nih.gov]

    Missing: 3HAP
  • Bacillus Anthracis

    Abstract N(5)-carboxy-amino-imidazole ribonucleotide (N(5)-CAIR) mutase (PurE), a bacterial enzyme in the de novo purine biosynthetic pathway, has been suggested to be a target[ncbi.nlm.nih.gov] Passive transfusion of mice with pulsed BMDC, concurrently with active immunisation with rPA in alum, significantly enhanced (p[ncbi.nlm.nih.gov] We discovered that while B. anthracis 34F2 Sterne endospores germinate poorly within non-activated human PMNs, these phagocytes exhibit rapid microbicidal activity toward[ncbi.nlm.nih.gov]

    Missing: 3HAP
  • Mycobacterium Smegmatis

    Abstract Chorismate mutase (CM) catalyzes the rearrangement of chorismate to prephenate in the biosynthetic pathway that forms phenylalanine and tyrosine in bacteria, fungi[ncbi.nlm.nih.gov] The determination of the temporal profile of alanine dehydrogenase activity during dormancy development showed that the activity stayed at a low baseline level during the[ncbi.nlm.nih.gov] Enzymes such as glucose-6-phosphate isomerase, 6-phosphofructokinase, fructose-bisphosphate aldolase, phosphoglycerate mutase, pyruvate kinase are encoded by more than 1 gene[bmcmicrobiol.biomedcentral.com]

    Missing: 3HAP
  • Methylmalonic Acidemia with Homocystinuria

    Both methionine synthase and methylmalonyl-CoA mutase activities are decreased in case of HMMA.[symptoma.com] Both methionine synthase and methylmalonyl-CoA mutase activities are decreased in case of HMMA.[symptoma.com] The mitochondrial generation of adenosylcobalamin is required for methylmalonyl-CoA mutase activity.[symptoma.com]

    Missing: 3HAP
  • Brugia Malayi

    Recently, UDP-galactopyranose mutases (UGM) have emerged as a promising drug target playing an important role in parasite virulence and survival.[ncbi.nlm.nih.gov] We evaluated the antifilarial activity of 6 flavonoids against the human lymphatic filarial parasite Brugia malayi using an in vitro motility assay with adult worms and microfilariae[ncbi.nlm.nih.gov] In this study, structural and immunological characterization of independent phosphoglycerate mutase of filarial parasite Brugia malayi was carried out.[ncbi.nlm.nih.gov]

    Missing: 3HAP
  • Methylmalonic Acidemia with Homocystinuria Type cblF

    Both methionine synthase and methylmalonyl-CoA mutase activities are decreased in case of HMMAF.[symptoma.com] Both methionine synthase and methylmalonyl-CoA mutase activities are decreased in case of HMMAF.[symptoma.com] Possibly, methylmalonyl-CoA mutase deficiency renders HMMAF patients susceptible to metabolic decompensation.[symptoma.com]

    Missing: 3HAP
  • Atypical Hemolytic Uremic Syndrome

    RATIONALE: Methylmalonic acidemia (MMA) is a common organic acidemia, mainly due to methylmalonyl-CoA mutase (MCM) or its coenzyme cobalamin (VitB12) metabolic disorders.[ncbi.nlm.nih.gov] […] as "cryptic activity of aHUS."[ncbi.nlm.nih.gov] We tested the in vitro ability of eculizumab to inhibit complement activation in HELLP serum.[ncbi.nlm.nih.gov]

    Missing: 3HAP
  • Methylmalonic Acidemia with Homocystinuria Type cblC

    Both methionine synthase and methylmalonyl-CoA mutase activities are decreased in case of HMMAC.[symptoma.com] […] disease is caused by mutations in the MMACHC gene and results in impaired intracellular synthesis of adenosylcobalamin and methylcobalamin, cofactors for the methylmalonyl-CoA mutase[ncbi.nlm.nih.gov] Both methionine synthase and methylmalonyl-CoA mutase activities are decreased in case of HMMAC.[symptoma.com]

    Missing: 3HAP
  • Homocystinuria

    Abstract Cobalamin is an essential cofactor for two mammalian enzymes: methionine synthase and methylmalonyl-CoA mutase.[ncbi.nlm.nih.gov] Decreased plasma CBS activity has been demonstrated in CBS-deficient patients with 16 different genotypes.[ncbi.nlm.nih.gov] The amount of the active phosphorylated forms of p38 and JNK stress-kinases was also increased.[ncbi.nlm.nih.gov]

    Missing: 3HAP
  • Erythrocytosis

    The patient's bisphosphoglycerate mutase (BPGM) enzyme activity was also markedly decreased at 0.16 IU/g Hb (normal 4.13-5.43 IU/g Hb).[ncbi.nlm.nih.gov] The angiogenic activity was evaluated by the assessment of the serum vascular endothelial growth factor (VEGF) levels, as one of circulating angiogenic factor, using a standardized[ncbi.nlm.nih.gov] […] erythrocytosis may be characterized by normal or high serum EPO levels, and is related to high oxygen affinity haemoglobin variants, mutation of the enzyme biphosphoglycerate mutase[ncbi.nlm.nih.gov]

    Missing: 3HAP