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41 Possible Causes for 3beta hydroxy, dehydrogenase, steroid

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  • Digitalis

    During the biosynthesis of cardiac glycosides, Delta (5)-3beta-hydroxysteroid dehydrogenase (3 beta HSD, EC converts pregnenolone (5-pregnen-3beta-ol-20-one) to[] Digitalis-like compounds (DLC) are a family of steroid hormones synthesized in and released from the adrenal gland.[] […] group and a 3beta-hydroxy group, the latter usually linked to one or more sugar rings.[]

  • Momordica Charantia

    11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the intracellular regeneration of active cortisol from inert cortisone in key metabolic tissues, thus regulating[] Three new cucurbitane-type triterpenoids, 5beta,19-epoxy-23(R)-methoxycucurbita-6,24-dien-3beta-ol (1), 5beta,19-epoxy-23(S)-methoxycucurbita-6,24-dien-3beta-ol (2), and 3beta-hydroxy[] Phytochemicals including proteins, polysaccharides, flavonoids, triterpenes, saponins, ascorbic acid and steroids have been found in this plant.[]

  • Niemann-Pick Disease Type C

    The urine of patients with Niemann-Pick diseases type C and 3β-hydroxysteroid dehydrogenase deficiency were analysed by precursor ion scan of m/z 97, 74, and 124.[] These acids were shown to have a 3beta-hydroxy-Delta(5) structure and to carry an oxo or hydroxy group at C-7.[] It is also the basic building block of steroid hormones , including neurosteroids .[]

  • Dehydroepiandrosterone

    Additionally, supplementation with DHEA in PORs decreased DNA damage and apoptosis in CCs while enhancing the mitochondrial mass, mitochondrial dehydrogenase activity and[] CAS 53-43-0 Deca Durabolin Steroids Dehydroisoandrosterone / DHEA / 3Beta-Hydroxy-5-Androsten-17-One Detailed Product Description: Deca Durabolin Steroids Dehydroisoandrosterone[] , and 4) steroid secretion studies in vitro of the tumor tissue, surrounding tissue, and contralateral ovarian tissue.[]

  • Combretum

    Compounds 1 and 5 also showed very strong inhibition of 3alpha-hydroxysteroid dehydrogenase with an IC(50) of 0.3 microg/ml.[] Brown ring at the boundary of mixture shows the presence of steroids. (N.B. Test tube was kept in ice as exo thermic reaction occurs.)[] In addition to four known triterpenoids, 1alpha,3beta-dihydroxy-12-oleanen-29-oic (1), 1-hydroxy-12-olean-30-oic acid (2), 3,30-dihydroxyl-12-oleanen-22-one (3), and 1,3,24[]

  • 2-Methylbutyryl-CoA Dehydrogenase Deficiency

    2-methylbutyryl-CoA dehydrogenase deficiency is an autosomal recessive disease characterized by an impairment in the degradation of isoleucine.[] Cheng JB, Jacquemin E, Gerhardt M, et al: Molecular genetics of 3beta-hydroxy-delta5-C27 steroid oxidoreductase deficiency in 16 patients with loss of bile acid synthesis[] Mitochondrial Fatty Acid Oxidation 309 Disorders of Carbohydrate and Glycogen Metabolism 335 Disorders of Glucose Transport 357 Genetic Dyslipoproteinemias 537 Disorders of Steroid[]

  • Alkylating Agent

    The mitochondrial membrane potential (ΔΨ(m)), O(2) consumption and dehydrogenase activities were rapidly dissipated/or inhibited by 3-BrPA in respiration medium containing[] ASE, namely 3beta-hydroxy-13alpha-amino-13,17-seco-5alpha-androstan-17-oic-13,17-lactam-p-bis(2-chloro-ethyl)amino phenylacetate (AzaSteroidalEster, NSC-71964), is an alkylating[] Abstract Growth velocity measurements were assessed in 12 children with steroid responsive but frequent relapsing or dependent nephrotic syndrome prior to and following treatment[]

  • Digitoxin

    Cell viability assays Lactate dehydrogenase cytotoxicity assay Measurement of lactate dehydrogenase in the conditioned media of drug-treated cells was done as previously described[] ,5beta)-hexopyranosyl)oxy]-14-hydroxy ; (3beta,5beta)-y)-14-hydroxy ; .4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-14-hydroxy-, (3beta,5beta)- ; .4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl[] We investigated the mechanism by which digitoxin, a member of the cardiotonic steroid class of drugs, regulates alternative splicing.[]

  • Bacillus Megaterium

    We have placed gdhA (encoding glucose dehydrogenase) from B. megaterium, lacZ (encoding beta-galactosidase) from E. coli, mro (encoding mutarotase) from Acinetobacter calcoaceticus[] -20(29)-en-28-oic acid, 1beta-hydroxy-3-oxo-lup-20(29)-en-28-oic acid, and 3beta,7beta, 15alpha-trihydroxy-lup-20(29)-en-28-oic acid based on nuclear magnetic resonance and[] Recently, it was shown that besides 3-oxo- 4-steroids, 3-hydroxy- 5-steroids as well as di- and triterpenes can also serve as substrates for this biocatalyst.[]

  • 3Beta-Hydroxy-Delta5-C27-Steroid Oxidoreductase Deficiency

    Other names in common use include: progesterone reductase Δ 5 -3β-hydroxysteroid dehydrogenase 3β-hydroxy-5-ene steroid dehydrogenase 3β-hydroxy steroid dehydrogenase/isomerase[] 3beta-hydroxy-delta5-c27-steroid oxidoreductase deficiency (3β-HSD) is an uncommon autosomal recessive disorder, characterized by defects in the synthesis of bile acids.[] ; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; C (27) -3BETA-HSD; short chain dehydrogenase/reductase family 11E; member 3; hydroxy-delta-5-steroid dehydrogenase[]