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23 Possible Causes for 4' deoxydoxorubicin, 7 deoxyaglycone

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  • Systemic Amyloidosis

    New drug therapy of amyloidoses: resorption of AL-type deposits with 4′-iodo-4′-deoxydoxorubicin. Blood 1995;86:855–61. PubMed Google Scholar 11.[link.springer.com] . : Treatment of AL amyloidosis with 4‘-lodo-4’-deoxydoxorubicin: an update [letter] . Blood 1999, 93 :1112–1113.[link.springer.com] -iodo-4′-deoxydoxorubicin with amyloid fibrils: Inhibition of amyloidogenesis.[cjasn.asnjournals.org]

    Missing: 7 deoxyaglycone
  • TTR Amyloidosis with Polyneuropathy

    ., A multicenter phase II trial of 4'-iodo-4' deoxydoxorubicin (IDOX) in primary amyloidosis (AL), Amyloid , 2002;9:24–30.[touchneurology.com] Palha JA, Ballinari D, Amboldi N, Cardoso I, Fernandes R, Bellotti V, et al. 4'-Iodo-4'-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid.[emedicine.medscape.com] ., 4'-iodo-4'- deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid, Am J Pathol , 2000;156:1919–25.[touchneurology.com]

    Missing: 7 deoxyaglycone
  • Primary Amyloidosis

    -iodo-4′-deoxydoxorubicin with amyloid fibrils: Inhibition of amyloidogenesis.[doi.org] A multicenter phase II trial of 4'-iodo-4'deoxydoxorubicin (IDOX) in primary amyloidosis (AL). Amyloid . 2002 Mar. 9(1):24-30. [Medline] .[emedicine.com] An iodinated derivative of doxorubicin, 4-iodo-4-deoxydoxorubicin (IDOX), binds with high affinity to amyloid fibrils and promotes their disaggregation in vitro and in vivo[doi.org]

    Missing: 7 deoxyaglycone
  • Hereditary ATTR Amyloidosis

    Palha JA, Ballinari D, Amboldi N, Cardoso I, Fernandes R, Bellotti V, et al. 4'-Iodo-4'-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid.[emedicine.medscape.com]

    Missing: 7 deoxyaglycone
  • Leptomeningeal TTR Amyloidosis

    Palha JA, Ballinari D, Amboldi N, Cardoso I, Fernandes R, Bellotti V, et al. 4'-Iodo-4'-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid.[emedicine.medscape.com] -iodo-4′-deoxydoxorubicin (I-DOX) and tetracyclines.[pharmaceuticalintelligence.com] […] of the proposed TTR stabilizers such as derivatives of some NSAIDs (diflunisal, diclofenac, flufenamic acid, and derivatives) and the action of amyloid disrupters such as 4[pharmaceuticalintelligence.com]

    Missing: 7 deoxyaglycone
  • Cardiac Amyloidosis

    Gertz MA, Lacy MQ, Dispenzieri A, et al: A multicenter phase II trial of 4′-iodo-4deoxydoxorubicin (IDOX) in primary amyloidosis (AL).[jco.ascopubs.org] Treatment of AL amyloidosis with 4’-iodo-4deoxydoxorubicin: an update. Blood 1999; 93 :1112–13. Gertz MA, Lacy MQ, Dispenzieri A et al .[bjcardio.co.uk] -iodo-4′-deoxydoxorubicin with amyloid fibrils: Inhibition of amyloidogenesis.[cjasn.asnjournals.org]

    Missing: 7 deoxyaglycone
  • Serum Neuropathy

    -iodo-4′-deoxydoxorubicin with amyloid fibrils: Inhibition of amyloidogenesis.[cjasn.asnjournals.org] An iodinated derivative of doxorubicin, 4-iodo-4-deoxydoxorubicin (IDOX), binds with high affinity to amyloid fibrils and promotes their disaggregation in vitro and in vivo[cjasn.asnjournals.org] Blood 2006 , in press Palha JA, Ballinari D, Amboldi N, Cardoso I, Fernandes R, Bellotti V, Merlini G, Saraiva MJ: 4′-Iodo-4′-deoxydoxorubicin disrupts the fibrillar structure[cjasn.asnjournals.org]

    Missing: 7 deoxyaglycone
  • TTR Amyloidosis with Cardiomyopathy

    Palha JA, Ballinari D, Amboldi N, Cardoso I, Fernandes R, Bellotti V, et al. 4'-Iodo-4'-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid.[emedicine.medscape.com] -iodo-4′-deoxydoxorubicin (I-DOX) and tetracyclines.[pharmaceuticalintelligence.com] […] of the proposed TTR stabilizers such as derivatives of some NSAIDs (diflunisal, diclofenac, flufenamic acid, and derivatives) and the action of amyloid disrupters such as 4[pharmaceuticalintelligence.com]

    Missing: 7 deoxyaglycone
  • Renal Amyloidosis

    The anthracycline derivative 4’-iodo-4’-deoxydoxorubicin (IDOX), was serendipitously noted to cause resorption of amyloid deposits in model systems but preliminary trials[bu.edu]

    Missing: 7 deoxyaglycone
  • Amyloidosis

    -iodo-4′-deoxydoxorubicin with amyloid fibrils: Inhibition of amyloidogenesis.[doi.org] An iodinated derivative of doxorubicin, 4-iodo-4-deoxydoxorubicin (IDOX), binds with high affinity to amyloid fibrils and promotes their disaggregation in vitro and in vivo[doi.org] Blood 2006 , in press Palha JA, Ballinari D, Amboldi N, Cardoso I, Fernandes R, Bellotti V, Merlini G, Saraiva MJ: 4′-Iodo-4′-deoxydoxorubicin disrupts the fibrillar structure[doi.org]

    Missing: 7 deoxyaglycone

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