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553 Possible Causes for 4' thiocytidine, 5 triphosphate

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  • Influenza

    It is phosphoribosylated by cellular enzymes to its active form, favipiravir-ribofuranosyl-5′-triphosphate (RTP).[ncbi.nlm.nih.gov] Favipiravir ribofuranosyl-5′-triphosphate (favipiravir-RTP) was identified, as was favipiravir-ribofuranose and favipiravir-ribofuranosyl-5′-monophosphate (favipiravir-RMP[ncbi.nlm.nih.gov] The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase.[ncbi.nlm.nih.gov]

    Missing: 4' thiocytidine
  • Tuberculosis

    Bedaquiline uses adenosine 5'-triphosphate (ATP) synthase inhibition as its mechanism of action, has in vitro activity against both replicating and nonreplicating bacilli,[cdc.gov]

    Missing: 4' thiocytidine
  • Spinocerebellar Ataxia Type 15

    This disease is caused by a heterozygous deletion of the inositol 1, 4, 5-triphosphate receptor type 1 (ITPR1) gene, suggesting that haploinsufficiency of the receptor function[ncbi.nlm.nih.gov] This disease is caused by mutations of the 5′ lesion of the inositol 1, 4, 5-triphosphate receptor type 1 ( ITPR1 ) gene.[nature.com] Product Name inositol 1, 4, 5-triphosphate receptor, type 1 (ITPR1), ELISA Kit Popular Item Also Known As Human Inositol 1, 4, 5-trisphosphate receptor type 1, ITPR1 ELISA[mybiosource.com]

    Missing: 4' thiocytidine
  • Stavudine

    Because thymidine kinase is under feedback regulatory control by the physiological deoxynucleoside-5'-triphosphate dTTP, we examined the effect on D4T phosphorylation and[ncbi.nlm.nih.gov] -5’-triphosphate Triethylammonium Salt CAS Number: 1795791-25-1 Alternate CAS #: Free acid: 26194-89-8 Molecular Formula: C₁₀H₁₅N₂O₁₃P₃ x(Et₃N) Appearance: White to Off-White[trc-canada.com] Stavudine is converted to stavudine 5'-triphosphate which competes with thymidine 5'-triphosphate for incorporation into viral DNA.[antimicrobe.org]

    Missing: 4' thiocytidine
  • Zidovudine

    Assays were developed to assess the mechanism of inhibition by the 5'-triphosphate of carbovir of HIV-1 reverse transcriptase using either RNA or DNA templates that contain[ncbi.nlm.nih.gov] Azidothymidine anabolism to the 5'-mono-, di-, and -triphosphate derivatives was similar in uninfected and HIV-infected cells.[doi.org] The level of azidothymidine monophosphate was high, whereas the levels of the di- and triphosphate were low (less than or equal to 5 microM and less than or equal to 2 microM[doi.org]

    Missing: 4' thiocytidine
  • Ganciclovir

    N-9001 Ganciclovir Triphosphate 9-(1,3-Dihydroxy-2-propoxymethyl)guanine-5'-Triphosphate, GCV-TP Extinction Coefficient: 13,600 Lmol -1 cm -1 at 252 nm Molecular Weight: 495.2[trilinkbiotech.com] The primary mechanism of ganciclovir action against CMV is inhibition of the replication of viral DNA by ganciclovir-5'-triphosphate (ganciclovir-TP).[ncbi.nlm.nih.gov] 5 µmole: 50 µL 10 µmole: 100 µL Certificate(s) of Analysis Ganciclovir is a synthetic acyclic-DNA guanine derivative, where the C2’ carbon bond is absent.[trilinkbiotech.com]

    Missing: 4' thiocytidine
  • Pyrimidine-5-Nucleotidase Deficiency

    […] uridine 5'-triphosphate (UTP) at pH 7.1.[ncbi.nlm.nih.gov] Abstract The pyrimidine nucleoside triphosphates (CTP, UTP) increase in the pyrimidine 5'-nucleotidase (P5N) deficient red blood cell (RBC) to a greater degree than do the[ncbi.nlm.nih.gov] In haemolysates from normal subjects, cytidine triphosphate (CTP) inhibited the activity of pyruvate kinase in a competitive manner for magnesium.[ncbi.nlm.nih.gov]

    Missing: 4' thiocytidine
  • Intellectual Disability - Alacrima - Achalasia Syndrome

    The function of GMPPA is not well defined, however it is a homolog of GMPPB which catalyzes the reaction that converts mannose-1-phosphate and guanosine-5′-triphosphate to[jhu.pure.elsevier.com] The function of GMPPA is not well defined, however it is a homolog of GMPPB which catalyzes the reaction that converts mannose‐1‐phosphate and guanosine‐5′‐triphosphate to[ingentaconnect.com]

    Missing: 4' thiocytidine
  • Cytarabine

    Inhibition of mammalian DNA polymerase by the 5'- triphosphate of 1- β- D- arabinofuranosylcytosine and the 5'- triphosphate of 9- β- D- arabinofuranoxyladenine Cancer Research[caymanchem.com] Cytarabine-5 -monophosphate is deaminated by deoxycytidylate deaminase, leading to the inactive uridine-5 -monophosphate analog. [15] Cytarabine-5 -triphosphate is a substrate[en.wikipedia.org] -triphosphate (ara-CTP) Target DNA polymerase Interaction Structure map map07041 Antineoplastics - antimetabolic agents map07046 Immunosuppressive agents Brite Anatomical[kegg.jp]

    Missing: 4' thiocytidine
  • Cladribine

    Pretreatment with cladribine increases the intracellular accumulation of the active metabolite of cytarabine, cytosine arabinoside 5'-triphosphate, by 36 to 40%.[ncbi.nlm.nih.gov] Saturation of 1-β-D-arabinofuranosylcytosine 5′-triphosphate accumulation in leukemia cells during high-dose 1-β-D-arabinofuranosylcytosine therapy.[doi.org] Pretreatment with cladribine increases the intracellular accumulation of the active metabolite of cytarabine, cytosine arabinoside 5′-triphosphate, by 36 to 40%.[doi.org]

    Missing: 4' thiocytidine

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