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1,063 Possible Causes for 4, Aldehyde, DEHYDROGENASE

  • Aldehyde

    Li W 1 , Zhou H 2 , Chu Y 3 , Wang X 3 , Luo R 3 , Yang L 3 , Polachi N 3 , Li X 3 , Chen M 4 , Huang L 5 , Yan X 6 , Guo Z 3 , Sun H 7 .[] Some aldehydes are substrates for aldehyde dehydrogenase enzymes which metabolize aldehydes in the body.[] These enzymes include alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which play a significant role in the metabolism of many biological substances and exist[]

  • Sjogren-Larsson Syndrome

    Furthermore, as might be predicted from the essential role of FALDH in leucotriene B(4) (LTB(4)) metabolism, elevated urinary concentrations of LTB(4) and 20-OH-LTB(4) were[] Toxicity of long-chain aldehydes for FALDH-deficient cells decreased almost to the level of unaffected keratinocytes.[] Studies of mutations in SLS should prove useful for understanding structure-function correlations in FALDH and other aldehyde dehydrogenase proteins.[]

  • Xanthinuria

    In order to study the purine metabolism in the hypouricemic condition of this disorder, a single oral dose of allopurinol (4-hydroxypyrazolo[3,4-d]pyrimidine) was administered[] […] lack aldehyde oxidase activity.[] The duodenal mucosa from the subject had no xanthine dehydrogenase protein while the mRNA level was not reduced.[]

  • Disulfiram

    Huang J 1, 2 , Campian JL 3, 4 , Gujar AD 5 , Tran DD 6, 3, 4 , Lockhart AC 3, 4 , DeWees TA 6 , Tsien CI 6, 3 , Kim AH 3, 5 .[] Disulfiram (DSF), an inhibitor of aldehyde dehydrogenase, is currently in clinical use for treating alcoholism.[] Through inhibition of aldehyde dehydrogenase, disulfiram heightens serum aldehyde concentration after alcohol ingestion and causes aversive disulfiram-ethanol reaction.[]

  • Influenza

    Older: 0/1/2/3 127/66/23/1 134/63/15/1 0.59 4 Younger: 0/1/2/3/4 109/75/29/4/0 108/75/25/4/1 0.87 4 Starting age of nursery school [ n (%)] 0.21 4 6 (35) 61 (29) 3 y 138[] Infectivity of the virion is easily inactivated by all alcoholic disinfectants, chlorine, aldehydes and temperature above 70 C. Sources[] […] lymphopenia, elevated amino-transaminases, thrombocytopenia, prolonged prothrombin time and activated partial thromboplastin time, increased D-Dimer, increased serum lactate dehydrogenase[]

  • Xanthinuria Type 1

    Diseases testing done with next gene sequencing NGS sample type Blood or DNA and reporing time is 4 to 5 weeks How to get tested Works Follow below step by step process to[] […] allopurinol to oxipurinol during an allopurinol loading test for determining the type of classical xanthinuria revealed that the patients had classical type 1 xanthinuria, because aldehyde[] Proteolytic conversion of xanthine dehydrogenase from the NAD-dependent type to the O2-dependent type.[]

  • Xanthinuria Type 2

    Showing of 4 5%-29% of people have these symptoms Nephrolithiasis Kidney stones 0000787 Renal insufficiency Renal failure Renal failure in adulthood [ more ] 0000083 Percent[] Also Known As Xanthine dehydrogenase and xanthine aldehyde oxydase dual deficiency[] […] of xanthine dehydrogenase and aldehyde oxidase.[]

  • Disulfiram-like Reaction

    Indian J Pharmacol. 2013 Jul-Aug;45(4):399-400. doi: 10.4103/0253-7613.114991.[] The protein expression of aldehyde dehydrogenase 2 was not affected at all.[] J Postgrad Med. 2009 Oct-Dec;55(4):292-3. doi: 10.4103/0022-3859.58940.[]

  • Osteoporosis

    Figures and Tables - Analysis 4.2 Comparison 4 Musculoskeletal pain, Outcome 2 Lower limb pain 4 years.[] IFNA8, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21 , Interferon α proteins [ 36 ] PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [ 36 ] Other pathways ALDH7A1 Aldehyde[] Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3β-hydroxy-steroid dehydrogenase . J Biol Chem 2001 ; 276: 16767 – 71 .[]

  • Deficiency of Sulfite Oxidase

    Mutation analysis of the sulfite oxidase gene revealed that the patient was homozygous for a novel 4-base pair deletion, and both of his parents were found to be heterozygous[] The cofactor is essential for the function of the human enzymes sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase.[] Abstract A patient suffering from a combined deficiency of sulfite oxidase (sulfite dehydrogenase; sulfite:ferricytochrome c oxidoreductase, EC and xanthine dehydrogenase[]

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