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6,159 Possible Causes for 4, CTCAE, Grade, Leak, Urethra

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  • Urinary Tract Infection

    […] children (age 0-5y) with first episode (age 0-1y) of UTI or recurrent (age RESULTS: Significant abnormalities were detected in 110 (63%), with vesicoureteric reflux (VUR) grades[ncbi.nlm.nih.gov] Therefore, CHF1 was further characterized by NMR and FTIR analysis and based on the structure elucidated, the compound was found to be 3,3',4'-Trihydroxyflavone.[ncbi.nlm.nih.gov] Infection of the urethra (urethritis). This type of UTI can occur when GI bacteria spread from the anus to the urethra.[mayoclinic.org] If you experience a sudden increase in the need to urinate often, or start to leak urine involuntarily, UTI could be the cause — especially if this is a new problem.[ucsfhealth.org] We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach[ncbi.nlm.nih.gov]

    Missing: CTCAE
  • Mitomycin

    The AEs reported were CTCAE Grade 1-2: Pain 13-27%, bladder spasms 6-27%and hematuria 3-20% are the most relevant. In general, CTCAE grade 3-4 toxicity is not reported.[ncbi.nlm.nih.gov] Punctal stenosis grade 0 (no punctum) occurred in 9 cases (30%), and grade 1 (the punctum is covered by a membrane) occurred in 21 cases (70%).[ncbi.nlm.nih.gov] Chemistry and Biology . 6 (4): 251–263. doi : 10.1016/S1074-5521(99)80040-4 . PMID 10099135 . Charpentier X, Kay E, Schneider D, Shuman HA (March 2011).[en.wikipedia.org] This is due to cystitis (inflammation of the bladder wall) and/or urethritis (inflammation of the urethra).[urologysurgeon.net] Four eyes of 3 patients with thin conjunctiva, precluding watertight conjunctival closure at the incision site with suturing, underwent intraoperative AM grafts over the leaking[ncbi.nlm.nih.gov]

  • Doxorubicin

    […] v4.0 [ Time Frame: 32 months ] Number of patients with SAE and SAE leading to withdrawal from the study Number of patients who died for SAE as assessed by CTCAE v4.0 [ Time[clinicaltrials.gov] Product Specifications Doxorubicin HCl, USP Grade Formula: C 27 H 29 NO 11 HCl MW: 579.98 g/mol Storage/Handling: Store desiccated at 2-8 C.[goldbio.com] These Dox-resistant TNBC cells showed activation of Stat3 and high expression levels of pluripotency transcription factors octamer-binding transcription factor-4 (Oct-4) and[ncbi.nlm.nih.gov] It occurs when there is an uncontrollable growth of cells in the prostate, a gland present below the bladder, near the rectum and around the urethra.[prostatecancernewstoday.com] However, a lung injury connected with its cytotoxic activity to pulmonary endothelium (capillary leak syndrome) can be an equally serious complication.[ncbi.nlm.nih.gov]

  • Vinorelbine

    Objective response and clinical benefit rates were calculated and toxicity was determined using the NCI-CTCAE criteria.[ncbi.nlm.nih.gov] %/0 %/2 %) and chemotherapy-mediated grade 3/4 toxicities (CRT/CC: neutropenia 11.2 %/22.1 %; leukopenia 18.3 %/26.7 %; grade 3 nausea 5.0 %/2.3 %, grade 3 vomiting 3.2 %[ncbi.nlm.nih.gov] Human umbilical vein endothelial cell cultures were treated with different concentrations of VRL (0.001 nmol/l to 1 mmol/l) for 4, 24 and 96 h.[ncbi.nlm.nih.gov] The prostate gland is located below the bladder, near the rectum and surrounding the urethra, and when it is affected by cancer, the cells of the prostate start to grow out[prostatecancernewstoday.com] Some patients might experience leaking around the vein . If Vinorelbine leaks into the tissues around the vein, it can damage tissue in that area.[cancernet.co.uk]

  • Testicular Germ Cell Tumor

    Incidence and severity of nausea were assessed based on the Common Terminology Criteria for Adverse Events (CTCAE) and a subjective rating scale completed by patients.[ncbi.nlm.nih.gov] Participants were queried separately about consumption of beer, wine and liquor during grades 7-8, grades 9-12 and the 5 years before reference date (date of diagnosis for[ncbi.nlm.nih.gov] Expression of APAF-1, Oct-3/4, and Ki-67 was significantly higher in seminomas than in non-seminomas.[ncbi.nlm.nih.gov] This fluid then enters the urethra, the tube in the center of the penis through which both urine and semen leave the body.[cancer.org] Only 1 patient had a postoperative chyle leak, which resolved spontaneously after several days.[ncbi.nlm.nih.gov]

  • Carmustine

    The primary outcome was the incidence of infusion-related reactions which were graded based on CTCAE 4.03 descriptions of flushing and infusion-related reactions.[ncbi.nlm.nih.gov] BACKGROUND: High-grade gliomas are aggressive brain tumours that are extremely challenging to treat effectively.[ncbi.nlm.nih.gov] […] and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore, Singapore, 117585. [email protected][ncbi.nlm.nih.gov] Possible mechanisms for the CSF leak in these patients are discussed.[ncbi.nlm.nih.gov] […] group AE rates from the two pivotal Phase III trials ranged from 4-23% for cerebral oedema, 4-9% for intracranial hypertension, 14-16% for healing abnormalities, 5% for CSF leaks[ncbi.nlm.nih.gov]

    Missing: Urethra
  • Vinblastine

    […] of toxicities of both steroids and vinblastine were recorded and graded according to the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE[ojrd.biomedcentral.com] PURPOSE: To evaluate the efficacy of single-agent vinblastine in pediatric patients with recurrent or refractory low-grade glioma.[ncbi.nlm.nih.gov] Heng MA 1 , Padovani L 2 , Dory-Lautrec P 3 , Gentet JC 1 , Verschuur A 1, 4 , Pasquier E 4, 5 , Figarella-Branger D 5, 6 , Scavarda D 7 , André N 1, 4, 5 .[ncbi.nlm.nih.gov] […] the internal iliac, femoral and popliteal arteries is reported in a 38-year-old man receiving intravenous cisplatin-vinblastine-methotrexate therapy for carcinoma of the urethra[ncbi.nlm.nih.gov] This medicine may cause tissue damage if the drug leaks from the vein.[drugs.com]

  • Myelodysplasia

    WHO/CTCAE grade 3 (or equivalent) or above).[ncbi.nlm.nih.gov] This group recently proposed the grading system for diagnostic accuracy of MDS, and the detailed procedure of morphological diagnosis of MDS is presented in the specialized[ncbi.nlm.nih.gov] Kim T 1, 2 , Tyndel MS 2, 3 , Kim HJ 4, 5 , Ahn JS 4, 5 , Choi SH 4 , Park HJ 4 , Kim YK 4, 5 , Yang DH 5 , Lee JJ 5 , Jung SH 5 , Kim SY 4, 5 , Min YH 6 , Cheong JW 6 , Sohn[ncbi.nlm.nih.gov] PURPOSE: The purpose of this study, is to find out the most accurate cut-off level for the detrusor leak point pressure (DLPP) in terms of upper urinary tract (UUT) protection[ncbi.nlm.nih.gov] Study and control groups 2 included 30 and 50 children with detrusor leak point pressure greater and less than 40 cm H2O, respectively.[ncbi.nlm.nih.gov]

    Missing: Urethra
  • Retroperitoneal Sarcoma

    Acute and chronic toxicities were assessed using the CTCAE v. 3 criteria. The actuarial 2 and 3-year OS was 66% for both and the 5-year OS was 51%.[ncbi.nlm.nih.gov] This is particularly true in case of high-grade sarcomas of specific histological subtypes, as demonstrated by the largest surveys of the last decade.[ncbi.nlm.nih.gov] At 3 years the distant metastasis-free survival rate was 100, 85·9 (77·4 to 91·4) and 65 (49 to 77) per cent, and the disease-specific survival rate was 97 (89 to 99), 78·[ncbi.nlm.nih.gov] Cases are grouped into sections that are organized by body part including: Kidney, Retroperitoneum, Adrenal, Ureter, Bladder, Prostate, Urethra, Vagina, Penis, Testis, Epididymis[books.google.ro] Postoperatively, 10 patients (34%) had major complications including 8 (28%) that developed a clinically-significant pancreatic leak.[ncbi.nlm.nih.gov]

  • Endometrial Stromal Sarcoma

    […] is that in case of severe liver toxicity pazopanib should be interrupted and restarted at a lower dose after returning to Common Terminology Criteria for Adverse Events (CTCAE[ncbi.nlm.nih.gov] BACKGROUND: The transition of low-grade endometrial stromal sarcoma (ESS) to high-grade ESS remains a rare clinical event.[ncbi.nlm.nih.gov] Collaborators (83) Chang YH 4 , Chang Y 4 , Chao HT 4 , Chao KC 4 , Chuang CM 4 , Ho CH 4 , Huang CY 4 , Hung ZC 4 , Jiang LY 4 , Lau HY 4 , Li HY 4 , Lin CY 4 , Liu CH 4[ncbi.nlm.nih.gov] Cystoscopy : A procedure to look inside the bladder and urethra to check for abnormal areas. A cystoscope is inserted through the urethra into the bladder.[cancer.gov] The cancer make-up had leaked into my pelvic area before the hysterectomy and unfortunately grew attaching itself to the bowel.[cancerresearchuk.org]