Create issue ticket

7,972 Possible Causes for 4, DOMAIN, REPEAT, TETRATRICOPEPTIDE

  • Novobiocin

    Abstract The C-terminal domain of Hsp90 displays independent chaperone activity, mediates dimerization, and contains the MEEVD motif essential for interaction with tetratricopeptide[] No correlation exists between the antimicrobial and cytotoxic activities of the 4-quinolones.[] Treatment cycles were repeated every 4 weeks.[] Aliquot to avoid repeated freezing and thawing. Store at -20 degree C.[]

  • Suramin

    In the absence of S100 proteins, suramin bound to the tetratricopeptide repeat (TPR) domain of PP5 and activated the enzyme in a dose-dependent manner.[] The docking results of both hFGF1-FGFR2 D2 domain and hFGF1-suramin complex were superimposed.[] PTP Inhibitor VI Primary Target: protein tyrosine phosphatases Overview Supporting Documentation Overview Key Spec Table Empirical Formula CAS # C₅₁H₃₄N₆O₂₃S₆ . 6Na 129-46-4[] Abstract The paper records the numbers of 1-2 mm shotty papules developing in the author's skin after 2-day courses of diethylcarbamazine (DEC) repeated every 16 days before[]

  • Gigantism

    The Q229X mutation was predicted to generate a truncated AIP protein, lacking the last two tetratricopeptide repeat domains and the final C-terminal α-7 helix.[] The HMGI-C protein has three AT-hook domains and an acidic COOH-terminal tail.[] , Stratakis CA 8 , Lupski JR 4, 11, 12, 13 , Beckers A 14 .[] Four of the nine patients who failed the initial surgery required a repeat procedure.[]

  • Treponema Denticola

    These genes include a four-member family of YD repeat proteins (carbohydrate-binding), 11 tetratricopeptide (TPR) repeat-containing proteins (protein–protein interactions)[] Treponema denticola sonicates adhered to recombinant Rgp domains.[] The potential of the hormonal steroids to inhibit growth was in the order of progesterone, 4-androstenedione and testosterone.[] Abstract The gene lrrA, encoding a leucine-rich repeat protein, LrrA, that contains eight consensus tandem repeats of 23 amino acid residues, has been identified in Treponema[]

  • Parainfluenza Virus

    The IFIT (interferon-induced proteins with tetratricopeptide repeats) family proteins constitute a major subclass of ISG proteins and are characterized by multiple tetratricopeptide[] IMPORTANCE We examined the importance of amino acids in the putative RNA-binding domain of hPIV2 NP for polymerase activity using minireplicons.[] METHODS: Hospital records of 13 patients from whom parainfluenza virus type 4 was isolated were retrospectively reviewed.[] This suggests that the interaction between NP and the N-terminal domain plays a critical role in V inhibition of viral RNA synthesis by the N-terminal domain.[]

  • Epilepsy

    Leu729ThrfsTer6) in TMTC3, encoding transmembrane and tetratricopeptide repeat containing 3, in four siblings with nocturnal seizures and ID.[] PURPOSE: Dishevelled EGL-10 and pleckstrin domain-containing protein 5 (DEPDC5) mutations are found in a wide spectrum of focal epilepsies ranging from epilepsy caused by[] A 27-year-old woman with a history of epilepsy and anti-epileptic drugs (AEDs) developed repeated seizures and neuropsychiatric symptoms after a 9-year asymptomatic interval[] Compared to controls, they showed more depressive symptoms, experienced more negative life events and had more often an ID discrepancy (ID profile with one domain particularly[]

  • Influenza

    For instance, the H3 HA has less disparity in mutational tolerance between the head and stalk domains than the H1 HA.[] Perdigão AC 1, 2, 3 , Ramalho IL 1, 2 , Guedes MI 2 , Braga DN 4, 5 , Cavalcanti LP 4 , Melo ME 1 , Araújo RM 6 , Lima EG 1, 2 , Silva LA 1 , Araújo Lde C 7 , Araújo FM 1,[] CLINICAL CASE: A patient that after seven years on NTZ therapy, testing on every 3 months repeated evaluations negative for anti-JCV status became positive ( 3 units) 4 weeks[] Because the flu viruses can change from year to year, vaccination needs to be repeated every year.[]

  • Pharyngitis

    As a result, the mutant CARD8 protein lost the ability to interact with the NOD domain of NLRP3.[] Tubbs RS 1, 2, 3 , Griessenauer CJ 1 , Hendrix P 1 , Oakes P 1 , Loukas M 2 , Chern JJ 4, 5 , Rozzelle CJ 1 , Oakes WJ 1 .[] VCI resulting from a malignant tumor was suspected at first, but repeated pathological examinations revealed CMV infection in the pharyngeal mucosa.[] Strain relatedness was determined by emm typing, multilocus sequence typing (MLST), multilocus variable tandem repeat analysis (MLVA), phage profiling (PP) and virulence factor[]

  • Herpes Simplex Virus 1

    The interferon-induced protein with tetratricopeptide repeat 3 (IFIT3 or ISG60) is a host-intrinsic antiviral factor that restricts many instances of DNA and RNA virus replication[] The functional regions of gD responsible for viral entry have been mapped to its extracellular domain, whereas the gD cytoplasmic domain plays no obvious role in viral entry[] The transcription level of the immediate-early gene α-4 in UL7-MU-infected cells was reduced by approximately 2-fold compared with the clear transcriptional peak identified[] In the other two cases, repeat cerebrospinal fluid (CSF) analysis showed persistent lymphocytic pleocytosis necessitating prolonged viral suppression.[]

  • Nephronophthisis

    […] repeat domain 21B tetratricopeptide repeat domain-containing protein 21B tetratricopeptide repeat-containing hedgehog modulator 1 TTC21B THM1 612014 25660 transmembrane protein[] Specifically, the R650C substitution is located within a G[QRC]LG repeat motif of the predicted seven bladed beta-propeller structure of the RCC1 domain.[] Six out of eight nphp-4 mutations analyzed alter ciliary function, and three of these modify the severity of the phenotypes caused by disruption of mksr-2 and mksr-1.[] 609799 NPHP9 SDCCAG8 serologically defined colon cancer antigen 8 613524 NPHP10 SLSN7 BBS16 LCA 80% TMEM67 transmembrane protein 67 609884 NPHP11 JBTS6 MKS3 BBS TTC21B * tetratricopeptide[]