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71 Possible Causes for 41kD, Antibody:Arbitrary, BLOT, Borrelia, Concentration:Point, burgdorferi, fluid:Ordinal:IMMUNE, IN, spinal, time:Cerebral

  • Borrelia Burgdorferi

    Abstract Lyme disease is emerging in eastern and central Canada, and most cases are diagnosed using the two-tier serological test (Enzyme Immuno Assay [EIA] followed by Western blot[ncbi.nlm.nih.gov] Abstract Phagocytosis of Borrelia burgdorferi, the causative agent of Lyme disease, is a poorly understood process, despite its importance during the host immune response[ncbi.nlm.nih.gov] Abstract The present paper describes a case of bilateral panuveitis due to Borrelia burgdorferi sensu lato diagnosed by a PCR approach using cerebral spinal fluid.[ncbi.nlm.nih.gov] The assessment of multiple tissue sites and two DNA resources at two different time points using Luminex Flex Map technology provides a robust data set.[ncbi.nlm.nih.gov] All sequences were compared with described alleles in the B. burgdorferi MLST database ( ), and new alleles were assigned arbitrary number designations.[pnas.org] OBJECTIVE: To determine the background levels and specificity of antibody to Borrelia burgdorferi by Western blot (immunoblot) in an area nonendemic for Lyme disease, and[ncbi.nlm.nih.gov] Moreover, patients with a spinal onset were not more frequently seropositive compared with patients with a bulbar onset (P 0.47), and neither were patients with a short diagnostic[ncbi.nlm.nih.gov] Cerebral atrophy was seen in Case 3.[ncbi.nlm.nih.gov] The frequent detection of this microorganism, especially in early lichen sclerosus, points to a specific involvement of B burgdorferi or other similar strains in the development[ncbi.nlm.nih.gov] The study pointed out that, according to the CDC, about 10-20% of Lyme disease patients treated with antibiotics for the recommended 2-4 weeks experience adverse health effects[weeksmd.com]

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  • Oligoarthritis

    […] tested for Ct DNA by ligase chain reaction, and serum was tested for Ct antibodies by enzyme-linked immunosorbent assay and Bb antibodies by hemagglutination test and Western blotting[ncbi.nlm.nih.gov] Emerg Infect Dis. 2015 Jun [date cited]. ; Austria; Borrelia bavariensis; Ladstatter S; Lyme borreliosis; Lyme disease; PCR; Pomberger G; Reiter M; Schotta AM; Stanek G.[ncbi.nlm.nih.gov] Laura Coates, University of Leeds: seronegative oligoarthritis infliximab intraarticular Additional relevant MeSH terms: Spondylarthropathies Spondylarthritis Spondylitis Spinal[clinicaltrials.gov] Diagnosis was established by means of the clinical history and a positive serology to Borrelia burgdorferi sensu strictu.[ncbi.nlm.nih.gov] Skeleton radiographs, hip and cerebral magnetic resonance imaging showed, respectively, erosive arthritis of the hips and stigmates of pituitary-stalk involvement.[ncbi.nlm.nih.gov] Predictors of outcome were sought, with the primary end point a complete response (no synovitis on clinical examination) at 12 weeks.[ncbi.nlm.nih.gov] IgA-alpha1AT complex levels in the sera of RA patients [mean 25.6 arbitrary units (au)] were significantly higher (P 0.0034) than those in patients with seronegative oligoarthritis[ncbi.nlm.nih.gov] Serology for B. burgdorferi was requested, including ELISA IgM/IgG 1/800 reagent negative and a Western blot that revealed presence of one IgM band and 3 IgG bands.[scielo.br] [3] Three subtypes [2] ANA (antinuclear antibodies) present - there is an increased risk of developing uveitis Juvenile AS ( ankylosing spondylitis ) - characterized by spinal[physio-pedia.com] Single-point and multipoint transmission disequilibrium tests were carried out with the ETDT and TDTPHASE packages.[ncbi.nlm.nih.gov]

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  • Lyme Arthritis

    We present the MRI features of Lyme disease of the hip in a 4-year-old boy who presented with hip pain and was found to have Lyme disease by Western blot.[ncbi.nlm.nih.gov] Abstract Borrelia burgdorferi, the agent of Lyme disease, selectively expresses genes in the arthropod vector and mammalian host.[ncbi.nlm.nih.gov] […] there may be heart and nervous system issues, Bell’s palsy (loss of muscle tone on one or both sides of the face), severe headache, neck stiffness due to inflammation of the spinal[arthritis.org] Direct immunofluorescence staining showed reactivity with anti-B. burgdorferi serum. Spirochetes were not seen in subcultured material.[ncbi.nlm.nih.gov] Reversible cerebral hypoperfusion in Lyme encephalopathy. Neur 1997; 49: 1661-70. L ogigian EL, Kaplan RF, Steere AC. Chronic neurologic manifestations of Lyme disease.[richtlijnendatabase.nl] Intraclonal diversity among plasma cells of close physical proximity points toward an ongoing process of diversification and affinity maturation, possibly driven by the chronic[ncbi.nlm.nih.gov] Whereas the 41kd protein is not unique to B. burgdorferi, the 23kd protein appears to be unique.[lymeneteurope.org] Subsequent Western blot analysis was negative for Borrelia burgdorferi antigens.[ncbi.nlm.nih.gov] Cerebrospinal fluid also may be taken from around the spinal cord through a spinal tap (lumbar puncture), to test for Lyme disease antibodies and inflammation and check for[drugs.com] Cerebrovascular neuroborreliosis with signs of vasculitis and cerebral ischemia has rarely been reported in children [ 51 ].[arthritis-research.biomedcentral.com]

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  • Treponema Pallidum

    […] confirmed by Venereal Disease Research Laboratory (VDRL) testing and dark ground illumination for T. pallidum, and enzyme-linked immunosorbent assay (ELISA) and Western blot[ncbi.nlm.nih.gov] Using a Borrelia burgdorferi-based heterologous system and gain-in-function approach, we show for the first time that a highly immunogenic lipoprotein TP0435 can be differentially[ncbi.nlm.nih.gov] […] subspecies pallidum (T. pallidum), which affects the meninges, cerebrospinal fluid, cranial nerves, and vasculature in early neurosyphilis, and additionally the brain and spinal[ncbi.nlm.nih.gov] ., destruction of nerve cells in the cerebral cortex (paresisi) and spinal cord (tabes dorsalis).[creative-diagnostics.com] Combining the detection of syphilis and HIV antibodies into one point-of-care test integrates syphilis screening into already existing HIV screening programs, which may be[ncbi.nlm.nih.gov] Latent Syphilis , by definition, is "hidden syphilis" and is broken into two arbitrary stages: early latent and late latent.[plaza.ufl.edu] Neonatal serum from the first case and fetal serum from the second case showed specific immunoglobulin M reactivity with the 47-kd antigen of T pallidum by Western blot assays[ncbi.nlm.nih.gov] Most common strains associated with Lyme disease: 1] Borrelia burgdorferi 2] Borrelia afzelii 3] Borrelia garinii Treponema pallidum Treponema pallidum Spirochaete bacterium[globalrph.com] CONCLUSIONS: Our results show the electronic reader to be a promising option for increasing the use of point-of-care testing programs.[ncbi.nlm.nih.gov] Western Blot and immuno fluorescence experiments revealed that flagellins-mediated IL-6 and IL-8 expressions are heavily dependent on ERK, p38, and NF-κB.[ncbi.nlm.nih.gov]

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  • Demyelinating Disease

    Western blot confirmed that c-MYC protein expression was also reduced.[brain.oxfordjournals.org] Presumably, persistence of borrelia in the organism could act as one of the autoimmune process triggers, resulting in the demyelinating disease.[ncbi.nlm.nih.gov] Little research exists regarding pediatric spinal cord demyelinating disease.[ncbi.nlm.nih.gov] […] may not necessarily be the fastest from the distal stimulation point.[ncbi.nlm.nih.gov] Like all classifications that are not based on etiology, this one has its shortcomings in that it is somewhat arbitrary.[accessmedicine.mhmedical.com] Bacterial infections, such as tuberculosis, syphilis, Lyme disease, and meningitis.[sickkids.ca] Lyme disease  Can be identical to MS (skin rash common) Susac syndrome  Clinical presentation, course different from MS  Classic triad of Encephalopathy ,Branch retinal[slideshare.net] Neurology Service, Hospital Universitario Central de Asturias, Oviedo, Spain. [email protected] Abstract Fluctuating neurological symptoms in an older patient most often point[ncbi.nlm.nih.gov] […] revealed a lesion of abnormal signal in the midbrain that could be attributed to subacute stroke; however, consecutive MRIs revealed multiple lesions of abnormal signal pointing[ncbi.nlm.nih.gov] CONTEXT: Tumor-like inflammatory demyelinating disease (TIDD) usually occurs in the brain and rarely occurs in the spinal cord.[ncbi.nlm.nih.gov]

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  • Fibromyalgia

    Subsequently, western blotting and immunohistochemical analyses of the hippocampus demonstrated that the protein expression levels of brain‑derived neurotrophic factor (BDNF[ncbi.nlm.nih.gov] , the spirochete responsible for Lyme disease, and its many co-infections were present in the patient’s body.[envita.com] I am an Upper Cervical Chiropractor that focuses on the relationship between the neck, spinal cord, and brain.[ocspinalcare.com] Abstract The aim of this study is to characterize in resting-state conditions the cerebral blood flow velocity (CBFV) signals of fibromyalgia patients.[ncbi.nlm.nih.gov] Clinicians conducted the Manual Tender Point Survey (MTPS) on the 18 standard tender points and 3 control points on patients enrolled in a separate treatment trial.[mdedge.com] When people seem to have many and severe trigger points, another arbitrary diagnostic label is often applied: “myofascial pain syndrome,” which is yet another way of saying[painscience.com] CBF velocities were recorded bilaterally in the anterior cerebral arteries (ACA) and middle cerebral arteries (MCA) of 24 fibromyalgia patients during exposure to two painful[ncbi.nlm.nih.gov] Abstract Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation (NIBS) method, which modulates the membrane potential of neurons in the cerebral[ncbi.nlm.nih.gov] disease.[books.google.es] BACKGROUND AND PURPOSE: With increased use of serotonergic medications, a condition triggered by serotonin excess within the brain and spinal cord has emerged and may be gaining[ncbi.nlm.nih.gov]

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  • Mycosis Fungoides

    The TOX expression in MF lesion by Western blot analysis. (A) CD4 protein expression in MF、BID and NS.[journals.plos.org] Borrelia burgdorferi (Bb) is the aetiologic agent of Lyme disease (LD), the most common tick-transmitted disease in the northern hemisphere ( Jaenson, 1991 ).[nature.com] Primary central nervous system (CNS) lymphoma originates in the brain or spinal cord and may be found in patients with acquired immunodeficiency syndrome (AIDS) or those whose[cancercenter.com] MR images showed normal morphology of the cerebellum, brainstem, and cerebral hemispheres.[ajnr.org] This report points to a possible association between fingolimod and skin lymphoproliferative disorder and emphasizes the need for periodic skin examination.[ncbi.nlm.nih.gov] Usually, such lymphoid infiltrates with an ambiguous clinical picture as well as a challenging, arbitrary histology at time of initial presentation reveal a dominant T-cell[wjgnet.com] […] patients in remission and can help determine whether additional treatment is necessary Lumbar puncture to determine if the brain is involved In addition, the cerebrospinal spinal[dovemed.com] Diagnostic algorithm for MF is a point-based system. Points are scored for clinical, histopathologic, molecular biologic, and immunopathologic categories.[5minuteconsult.com] Clinical and histopathologic sections are further divided into basic and additional criteria: If basic criteria and two additional points are met, 2 points are given.[clinicaladvisor.com] […] abnormal liver function tests, or radiologic tests (CT, fludeoxyglucose-positron emission tomography, and liver or spleen scan) and should be confirmed by liver biopsy. 3 Cerebral[emjreviews.com]

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  • Staphylococcus Epidermidis

    Dot blot immune assays, confocal laser scanning microscopy, and qPCR showed that under biofilm inducing conditions, tigecycline augmented embp expression compared to the control[ncbi.nlm.nih.gov] Pseudomonas aeruginosa) Propionibacterium acnes Corynebakterien Chronische Meningitis HIV Borrelia burgdorferii Mycobacterium tuberculosis Treponema pallidum Actinomyzeten[de.wikibooks.org] OBJECTIVE: To determine relevant demographics, clinical presentations, and outcomes of surgical site infections (SSIs) after spinal instrumentation (SI) surgery caused by[ncbi.nlm.nih.gov] Abstract A 26-year-old woman receiving intrathecal chemotherapy for acute leukemia developed Ommaya-catheter-associated cerebritis and bacteremia caused by two clones of Staphylococcus[ncbi.nlm.nih.gov] The poor outcomes in these cases point to the need for alternative therapies with potent activity against methicillin-resistant CoNS.[ncbi.nlm.nih.gov] The results are presented as the means and standard deviations of the proportion of cells bearing bacteria (A) and of arbitrary fluorescence units (AFUs) (B).[journals.plos.org] Quantitative real time-polymerase chain reaction, Western blot, enzyme-linked immunosorbent assay, and immunocytochemistry techniques were performed to interrogate the mucin[ncbi.nlm.nih.gov] Author information 1 Center for Orthopaedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany[ncbi.nlm.nih.gov] Direct aspiration of the cerebral spinal fluid shunt is obtained, and CSF analysis demonstrates a leukocytosis, elevated protein, and decreased glucose.[step1.medbullets.com] Next, we constructed three psm-mec deletion mutants, one psm-mec transgene expression strain (p221) and two psm-mec point mutant strains (pM, pAG) to explore its effects on[ncbi.nlm.nih.gov]

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  • Chlamydophila Pneumoniae

    […] human infection sera of C. pneumoniae but not in Legionella pneumophila and Mycoplasma pneumoniae infection sera, showing high specificity and sensitivity by MIF, western blot[ncbi.nlm.nih.gov] In addition to this one bacterium there are other important ones that are Intracellular, like Borrelia burgdorferi aka Lyme Disease 55-57 , Mycoplasma 30, 33 , Bartonella[asthmastory.com] Chlamydia pneumoniae sequence frequently present in both MS and control spinal fluid [abstract]. Neurol 2000 ; 54 (suppl 3) : A165 .[jnnp.bmj.com] C. pneumoniae induced decreases in both KCl- and u46619-induced contractile responses at both time points.[ncbi.nlm.nih.gov] The result is expressed as an INDEX (ratio between the OD value of the sample and that of the Cut-off) and in Arbitrary Units (AU/ml). 0.10 Mb Chorus CHLAMYDOPHILA PNEUMONIAE[diesse.it] […] clinically compatible with acute C. pneumoniae infection was characterised by only increase of specific IgM antibodies detected by microimmunofluorescence, EIA and Western blot[ncbi.nlm.nih.gov] disease).[arminlabs.com] The main complications are bleeding, thromboembolism, cannula-related complications, pulmonary embolism or infarction, aortic thrombosis and coronary or cerebral hypoxemia[jmedicalcasereports.biomedcentral.com] Extracts of Saccharomyces cerevisiae cells expressing GFP-tagged C. pneumoniae proteins were subjected to Western blot analysis using serum samples from C. pneumoniae-infected[ncbi.nlm.nih.gov] Cpn infection explains this very well. n Secondary porphyria induced by it and the impact of porphyrins on brain functioning. n Cerebral inflammation from circulating cytokines[prohealth.com]

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  • Dengue Virus

    […] usefulness of dengue viral antigens as a postmortem diagnostic technique to demonstrate the presence of virus in human tissue specimens by immunohistochemistry and Western blotting[ncbi.nlm.nih.gov] Organism West Nile virus Japanese encephalitis virus Saint Louis encephalitis virus Yellow fever virus Hepatitis A virus Hepatitis B virus Hepatitis C virus Epstein Barr virus Borrelia[fda.gov] Further studies need to be performed to elucidate the mechanisms of spinal neurological damage in dengue.[ncbi.nlm.nih.gov] Although, neurological complication and hemostatic disturbance are common in dengue virus infection, cerebral ischaemia is barely mentioned.[ncbi.nlm.nih.gov] These cases stress the importance of investigating Dengue virus infections in febrile travellers, point to the potential for local outbreak of Dengue virus infection and emphasize[ncbi.nlm.nih.gov] The fit of data is arbitrary.[bloodjournal.org] The cellular targets of miR-3614-5p were identified by liquid chromatography/mass spectrometry and western blot.[ncbi.nlm.nih.gov] […] aimed to investigate the differences in miRNA expression patterns in human peripheral blood mononuclear cells (PBMCs) infected with DENV-3 and DENV-3-ADE at various time points[ncbi.nlm.nih.gov] The diagnosis is made by demonstrating specific antibodies to the virus in blood or spinal fluid. What is the treatment for dengue fever?[www1.nyc.gov] The differentiation between invasive and noninvasive is an arbitrary term often used to differentiate between established and new species of DENV.[microbewiki.kenyon.edu]

    Missing: 41kD IN

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