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680 Possible Causes for 5' triphosphate, N(4) (6 aminohexyl)cytidine

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  • Influenza

    The ambiguous base‐pairing and high substrate efficiency of T‐705 (favipiravir) ribofuranosyl 5′‐triphosphate towards influenza A virus polymerase .[ncbi.nlm.nih.gov] Lin L, Liu Q, Berube N, Detmer S, Zhou Y. 5′‐Triphosphate‐short interfering RNA: Potent inhibition of influenza A virus infection by gene silencing and RIG‐I activation .[ncbi.nlm.nih.gov]

    Missing: N(4) (6 aminohexyl)cytidine
  • Malignant Neoplasm

    […] glucose to lactate which they secrete, even in the presence of sufficient oxygen [5].[doi.org] In 1924, Warburg found that cancer cells mainly rely on aerobic glycolysis : they produce a large proportion of the adenosine triphosphate (ATP) they need by metabolising[doi.org]

    Missing: N(4) (6 aminohexyl)cytidine
  • Tuberculosis

    Bedaquiline uses adenosine 5'-triphosphate (ATP) synthase inhibition as its mechanism of action, has in vitro activity against both replicating and nonreplicating bacilli,[cdc.gov]

    Missing: N(4) (6 aminohexyl)cytidine
  • Spinocerebellar Ataxia Type 15

    This disease is caused by a heterozygous deletion of the inositol 1, 4, 5-triphosphate receptor type 1 (ITPR1) gene, suggesting that haploinsufficiency of the receptor function[ncbi.nlm.nih.gov] This disease is caused by mutations of the 5′ lesion of the inositol 1, 4, 5-triphosphate receptor type 1 ( ITPR1 ) gene.[nature.com] Product Name inositol 1, 4, 5-triphosphate receptor, type 1 (ITPR1), ELISA Kit Popular Item Also Known As Human Inositol 1, 4, 5-trisphosphate receptor type 1, ITPR1 ELISA[mybiosource.com]

    Missing: N(4) (6 aminohexyl)cytidine
  • Zidovudine

    Azidothymidine anabolism to the 5'-mono-, di-, and -triphosphate derivatives was similar in uninfected and HIV-infected cells.[ncbi.nlm.nih.gov] Assays were developed to assess the mechanism of inhibition by the 5'-triphosphate of carbovir of HIV-1 reverse transcriptase using either RNA or DNA templates that contain[ncbi.nlm.nih.gov] The level of azidothymidine monophosphate was high, whereas the levels of the di- and triphosphate were low (less than or equal to 5 microM and less than or equal to 2 microM[ncbi.nlm.nih.gov]

    Missing: N(4) (6 aminohexyl)cytidine
  • Ganciclovir

    N-9001 Ganciclovir Triphosphate 9-(1,3-Dihydroxy-2-propoxymethyl)guanine-5'-Triphosphate, GCV-TP Extinction Coefficient: 13,600 Lmol -1 cm -1 at 252 nm Molecular Weight: 495.2[trilinkbiotech.com] The primary mechanism of ganciclovir action against CMV is inhibition of the replication of viral DNA by ganciclovir-5'-triphosphate (ganciclovir-TP).[ncbi.nlm.nih.gov] 5 µmole: 50 µL 10 µmole: 100 µL Certificate(s) of Analysis Ganciclovir is a synthetic acyclic-DNA guanine derivative, where the C2’ carbon bond is absent.[trilinkbiotech.com]

    Missing: N(4) (6 aminohexyl)cytidine
  • Stavudine

    Because thymidine kinase is under feedback regulatory control by the physiological deoxynucleoside-5'-triphosphate dTTP, we examined the effect on D4T phosphorylation and[ncbi.nlm.nih.gov] -5’-triphosphate Triethylammonium Salt Impurity: CAS Number: 1795791-25-1 Alternate CAS #: Free acid: 26194-89-8 Molecular form.: C₁₀H₁₅N₂O₁₃P₃ x(Et₃N) Appearance: White to[trc-canada.com] Stavudine is converted to stavudine 5'-triphosphate which competes with thymidine 5'-triphosphate for incorporation into viral DNA.[antimicrobe.org]

    Missing: N(4) (6 aminohexyl)cytidine
  • Cytarabine

    Cytarabine-5 -triphosphate is a substrate for SAMDH1.[en.wikipedia.org] Inhibition of mammalian DNA polymerase by the 5'- triphosphate of 1- β- D- arabinofuranosylcytosine and the 5'- triphosphate of 9- β- D- arabinofuranoxyladenine Cancer Research[caymanchem.com] -triphosphate (ara-CTP) Target DNA polymerase Interaction Structure map map07041 Antineoplastics - antimetabolic agents map07046 Immunosuppressive agents Brite Anatomical[kegg.jp]

    Missing: N(4) (6 aminohexyl)cytidine
  • Pyrimidine-5-Nucleotidase Deficiency

    […] uridine 5'-triphosphate (UTP) at pH 7.1.[ncbi.nlm.nih.gov] Abstract The pyrimidine nucleoside triphosphates (CTP, UTP) increase in the pyrimidine 5'-nucleotidase (P5N) deficient red blood cell (RBC) to a greater degree than do the[ncbi.nlm.nih.gov] In haemolysates from normal subjects, cytidine triphosphate (CTP) inhibited the activity of pyruvate kinase in a competitive manner for magnesium.[ncbi.nlm.nih.gov]

    Missing: N(4) (6 aminohexyl)cytidine
  • Intellectual Disability - Alacrima - Achalasia Syndrome

    The function of GMPPA is not well defined, however it is a homolog of GMPPB which catalyzes the reaction that converts mannose-1-phosphate and guanosine-5′-triphosphate to[jhu.pure.elsevier.com] The function of GMPPA is not well defined, however it is a homolog of GMPPB which catalyzes the reaction that converts mannose‐1‐phosphate and guanosine‐5′‐triphosphate to[ingentaconnect.com]

    Missing: N(4) (6 aminohexyl)cytidine

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