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908 Possible Causes for 5, Aldehyde, DEHYDROGENASE

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  • Chemotherapy

    Many reports suggest that aldehyde dehydrogenase 1 (ALDH1) expression is associated with poorer neoadjuvant chemotherapy (NAC) response in patients with breast cancer; however[ncbi.nlm.nih.gov] This randomized phase III trial compared hepatic arterial infusion (HAI) chemotherapy with 5-fluorouracil (5-FU) followed by uracil/tegafur (UFT) and leucovorin (LV) versus[ncbi.nlm.nih.gov] Several gene mutations are listed in the pathogenesis of PGL, among which succinate dehydrogenase (SDHX), particularly the SDHB isoform, is the main gene involved in malignancy[ncbi.nlm.nih.gov]

  • Pyridoxine

    There is marked elevation of α-amino adipic semi-aldehyde (αAASA), piperidine-6-carboxylate (P6C) and pipecolic acid.[ncbi.nlm.nih.gov] Pyridoxal-5'-phosphate oxidase (PNPO) deficiency presents as a severe neonatal encephalopathy responsive to pyridoxal-5'-phosphate (PLP) or pyridoxine.[ncbi.nlm.nih.gov] Recently described biochemical and molecular pathology improved the diagnostic process for those cases in which seizures are caused by alpha amino adipic semialdehyde dehydrogenase[ncbi.nlm.nih.gov]

  • Phenothiazine

    Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents[chemicalbook.com] Values represent results from 5 samples, each obtained by pooling 6 individual plasmas (4 male and 2 female; n 30 healthy, drug-free volunteers).[ncbi.nlm.nih.gov] Peroxidase/H2O2/phenothiazine systems irreversibly inhibit Trypanosoma cruzi dihydrolipoamide dehydrogenase (LADH).[ncbi.nlm.nih.gov]

  • Francisella Tularensis

    In addition, the ultrastructural preservation of bacteria was compared using either chemical fixation by aldehydes and a standard resin embedding protocol or high-pressure[duo.uio.no] […] mouse model of infection, immuno-histochemistry identified that iNOS positive ("classical") macrophages are present at 72 h post-infection and remain high (supported by CCL-5[ncbi.nlm.nih.gov] The virulence of F. tularensis is decreased by deletion of guaB, the gene encoding IMP dehydrogenase (IMPDH), suggesting that this enzyme is a target for antibacterial design[ncbi.nlm.nih.gov]

  • Ischemia

    Aldehyde dehydrogenase 2 (ALDH2) is best known for its critical detoxifying role in liver alcohol metabolism.[ncbi.nlm.nih.gov] To address this knowledge gap, we performed an open-label treatment trial to assess whether phosphodiesterase type 5 inhibition improves coronary microvascular perfusion and[ncbi.nlm.nih.gov] It is interesting that XST can alter the expression of 7 proteins, including pyruvate dehydrogenase E1 alpha (PDHA1), hydroxyacyl-coenzyme A dehydrogenase (HADHA), peroxiredoxin[pubs.rsc.org]

  • Aldehyde

    The group—without R—is the aldehyde group , also known as the formyl group . Aldehydes are common in organic chemistry . Many fragrances are aldehydes.[en.wikipedia.org] […] reduced (2-oxo-5-aminoquinoline, 2-oxo-5AQ) metabolites.[ncbi.nlm.nih.gov] These enzymes include alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which play a significant role in the metabolism of many biological substances and exist[ncbi.nlm.nih.gov]

  • Bacillus Stearothermophilus

    ADH 2334 is encoded in a transcription unit containing an aldehyde dehydrogenase.[ncbi.nlm.nih.gov] The immunosuppressive profile of Bacillus stearothermophilus UK563 component, Fr.5-B, is presented in in vitro studies.[ncbi.nlm.nih.gov] […] of the pyruvate dehydrogenase complex of Bacillus stearothermophilus has been cloned in Escherichia coli.[ncbi.nlm.nih.gov]

  • Doxycycline

    Our results revealed that doxycycline significantly decreased the frequency of aldehyde dehydrogenase‑positive (ALDH ) BCSCs as well as mammosphere formation efficiency in[ncbi.nlm.nih.gov] Lyme disease-- current state of knowledge Dtsch.Arztebl.Int. 106(5), (2009) . 3. Steinhardt, L.C., Magill, A.J., and Arguin, P.M.[caymanchem.com] Serotonergic Neurons Tetracycline Inducible Gene.A simple method for the synthesis of benzylamino coumarin derivatives has been developed from secondary amines, aromatic aldehyde[yobbstools.cf]

  • Psoralen

    Aldehyde dehydrogenase 2 (ALDH2), one of 19 ALDH superfamily members, catalyzes the NAD -dependent oxidation of aldehydes to their respective carboxylic acids.[ncbi.nlm.nih.gov] Psoralen Catalogue number: P839800 Chemical name: Psoralen Synonyms: 7H-Furo[3,2-g][1]benzopyran-7-one; Furocoumarin; 3-(6-Hydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone[trc-canada.com] Their preparations were carried out by Reimer-Tiemann formylation to introduce the aldehyde group in an ortho position to the hydroxyl group.[repositorium.sdum.uminho.pt]

  • Sorbitol

    The role of aldehyde reductase tyrosine phenol group is to serve as a general acid to provide proton to the reduced aldehyde oxygen on glucose.[en.wikipedia.org] SDH2ab mRNAs increased after exposing diapause eggs to 5 C for 40 days, beginning at 2 days post-oviposition, to break diapause.[ncbi.nlm.nih.gov] Co-ordination of catalytic Zn2 in sorbitol/xylitol dehydrogenases of the medium-chain dehydrogenase/reductase superfamily involves direct or water-mediated interactions from[ncbi.nlm.nih.gov]

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