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3,707 Possible Causes for 5, Absolute, CTCAE, Cecum, Count, Grade, Infection, Neutrophil, Unknown, with

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  • Febrile Neutropenia

    Polymicrobial infection in patients with cancer: an underappreciated and underreported entity. Clin Infect Dis. 2007;45:228-233. 29.[uspharmacist.com] The definition of FN was used the criteria of CTCAE (ver. 4.0).[erj.ersjournals.com] All studies included people with cancer with fever of unknown origin and excluded people with microbiological documented infections.[cochrane.org] The patient's clinical manifestations resolved 5 days later.[ncbi.nlm.nih.gov] The proportion of severe adverse events (CTC-NCI grades 3/4) was low in both periods (4 and 1%).[bloodjournal.org] Neutropenia is defined as an absolute neutrophil count (polymorphonuclear cells plus band forms) of 500/ml or less.[jpgmonline.com] […] available electronic medical record data between January 2009 and December 2011, we examined cases of chemotherapy -induced neutropenia reported in our hospital using the CTCAE[journals.lww.com] In the USA, a mortality rate associated with grade 3 and 4 neutropenia ranging from 3.4 % to 10.5% with an overall mortality ranging from 6.8% to 9.5% was reported Ozguler[medcraveonline.com] It is defined as a temperature higher than 38.3 degrees Celsius or 100.5 degrees Farenheit in the presence of any severity of neutropenia, which is typically an absolute neutrophil[mdmag.com] […] origin (FUO) (ii) microbiologically documented infection (MDI) (iii) clinically documented infection (CDI) and according to the suspected source or site of infection (unknown[jpma.org.pk]

    Missing: Cecum with
  • Appendicitis

    Appendicitis was the origin of the soft tissue infection. The abdominal wall was only secondarily involved.[ncbi.nlm.nih.gov] This rare cancer, whose cause remains unknown, is likely found in less than 2 percent of all appendectomy specimens analyzed under a microscope, Dr. Ehlers said.[sciencedaily.com] […] with right lower quadrant pain and tenderness, mild neutrophilia and clinical presentation consistent with appendicitis, despite undergoing a laparoscopic appendicectomy 5[ncbi.nlm.nih.gov] For a secondary analysis, the oral contrast group was subdivided into "complete" (contrast extending into the cecum) or "partial" contrast.[ncbi.nlm.nih.gov] Grades of perforation were: I, 20.5%; II, 37.7%; III, 10.7%; IV, 31.1%.[ncbi.nlm.nih.gov] Blood samples were collected to measure suPAR level, C-reactive protein level, leukocyte counts, neutrophil counts, and neutrophil percentages preoperatively.[ncbi.nlm.nih.gov] A 55-year female presented in surgical emergency with 3 days history of abdominal pain, distension and absolute constipation; and 2 days history of vomiting.[ncbi.nlm.nih.gov] While appendicitis is much less common, about 5% of the population eventually ends up with it, and if you fall into that unlucky group, you'll need to figure it out as soon[prevention.com] A white blood cell count of less than 10,000/microL decreases the likelihood of appendicitis (summary LR, 0.22; 95% CI, 0.17-0.30), as does an absolute neutrophil count of[ncbi.nlm.nih.gov] […] definitive, one-time only treatment with a well-known risk profile, whereas the long-term impact of antibiotic treatment on patient quality of life and health care costs is unknown[ncbi.nlm.nih.gov]

    Missing: CTCAE with
  • Cyclic Neutropenia

    Abstract Atraumatic Clostridium septicum infection is rare in infancy and childhood and is associated with a high mortality rate.[ncbi.nlm.nih.gov] Abstract Fever of unknown origin (FUO) is the diagnosis associated with a variety of infectious, neoplastic, or rheumatic/inflammatory disorders.[ncbi.nlm.nih.gov] Epidemiology Most patients present before the age of 5 years: 32% are 27% are between ages 1 and 5 years.[unboundmedicine.com] Abstract Cyclic neutropenia, a rare blood disorder, may be complicated by spontaneous necrosis of the cecum and ascending colon.[ncbi.nlm.nih.gov] Further work up of the patient for high grade fever and occasional leukopenias revealed the diagnosis of cyclic neutropenia.[ncbi.nlm.nih.gov] Cyclic therapy with G-CSF (5 micrograms/kg/d s.c. for 1 week every 21 d) maintained peripheral neutrophil count above the normal range, reduced the incidence of severe infections[ncbi.nlm.nih.gov] The authors hypothesized that congenital neutropenia is also due to mutations of neutrophil elastase.[ncbi.nlm.nih.gov] When G-CSF therapy was discontinued, the leukocyte and absolute neutrophil counts again declined.[ncbi.nlm.nih.gov] Because of its rarity, location, and an unknown association with CN, we found this case worthwhile to publish.[ncbi.nlm.nih.gov] At the time of laparotomy, inflammation of the cecum, with no gross perforation, was found; no resection or appendectomy was done.[ncbi.nlm.nih.gov]

    Missing: CTCAE with
  • Lymphocytopenia

    infection.[ncbi.nlm.nih.gov] Lymphopenia was classified according to CTCAE (Common Terminology Criteria for Adverse Events) version 4.[doi.org] After cord blood transplantation, CD4( ) lymphocytopenia from unknown causes was observed, and persistent infections with human parvovirus B19 (B19) occurred.[ncbi.nlm.nih.gov] Comment to Haematologica. 2011;96(8):1221–5 Haematologica April 2012 97: e9-e11; doi: 10.3324/haematol.2011.058669 We read with interest a recent article in Haematologica[haematologica.org] A significant correlation of total leukocyte count and NLCR, but not lymphocyte count, with parasitaemia was found.[ncbi.nlm.nih.gov] Likewise, the neutrophil-lymphocyte count ratio (NLCR) has been shown a simple promising method to evaluate systemic inflammation in critically ill patients.[ncbi.nlm.nih.gov] In univariate analysis, subnormal absolute lymphocyte count (ALC) 9 /l; P 0.001), ALC 9 /l (P 0.0002), subnormal absolute monocyte count (AMC) 9 /l (P 0.0003), LMR (P 0.0001[ncbi.nlm.nih.gov] Background: Idiopathic CD4 lymphocytopenia (ICL) is a rare disorder of unknown etiology.[ingentaconnect.com] The normal absolute lymphocyte count is significantly higher in childhood.[mhmedical.com] The cause of this condition remains unknown; these cases may represent a heterogeneous group of disorders.[cdc.gov]

    Missing: Cecum with
  • Barth Syndrome

    For affected individuals with confirmed neutropenia, complications due to bacterial infection are often preventable by ongoing monitoring and early therapy of suspected infections[checkorphan.org] In some cases, a new mutation of the gene occurs randomly for unknown reasons.[childrenshospital.org] 代謝 本疾患で認められる3-メチルグルタコン酸尿症は,ミトコンドリア機能障害による二次的な3-メチルグルタコン酸増加が原因と考えられるが,その機序は十分に解明されていない 27) .現在,3-メチルグルタコンサン尿症は5型に分けられ,Barth症候群はII群に分類されている 5, 6) .3-メチルグルタコン酸尿は診断に有用であるが, TAZ[jpccs.jp] […] bladder 753.8 bone(s) 756.9 brain 742.4 breast 757.6 broad ligament 752.19 bronchus 748.3 canal of Nuck 752.89 cardiac septal closure 745.8 carpus 755.59 cartilaginous 756.9 cecum[icd9data.com] Data from these boys were compared to data from 15 typically developing boys individually matched on age and grade in school to each of the 15 boys with Barth syndrome.[dx.doi.org] Comparisons of reported events for the population suggest that patients with baseline neutrophil counts 0.5 x 10 9 /L have more infections than patients with higher counts[bloodjournal.org] (A,D,F) Freshly purified control neutrophils; (B) neutrophils from the same donor after overnight culture with more than 80% annexin-V binding; (C,E,G) freshly purified neutrophils[dx.doi.org] Laboratory analysis revealed low total white blood cell count (absolute count: 4000 cells per microL) in 25% of those who were not on granulocyte colony-stimulating factor[ncbi.nlm.nih.gov] Barth syndrome is due to mutations in the TAZ gene, the exact function of which is unknown but there are indications that it is directly involved in the metabolism of cardiolipin[genome.jp] […] aim to address these hypotheses through left ventricular function, skeletal muscle oxygen extraction/utilization, and whole body oxygen consumption measurements during a graded[clinicaltrials.gov]

    Missing: CTCAE with
  • Drug-induced Neutropenia

    However, pneumonia, gastrointestinal and genitourinary infections, but also systemic infections that lead to life-threatening sepsis and substantial morbidity/mortality may[symptoma.com] Discussion AOSD and SS are inflammatory diseases of unknown etiology, which share several clinical characteristics (high-grade fever, neutrophilic urticarial dermatosis and[em-consulte.com] In approximately 5% of cases drug-induced agranulocytosis may be fatal.[ncbi.nlm.nih.gov] […] chemotherapy, usually in neutropenic patients Involves antineoplastic agent-induced damage to intestinal mucosa Usually occurs in the terminal ileum, ascending colon, and cecum[enotes.tripod.com] Because several target antigens of ANCA are expressed on the surface of neutrophils, it was suggested that ANCA might contribute to neutropenia.[ncbi.nlm.nih.gov] In addition, the delta MNV and delta MNS were respectively correlated well with delta absolute neutrophil counts when neutropenia occurred.[ncbi.nlm.nih.gov] Two years ago, she had been prescribed oral and injected risperidone (CONSTA ) at another institution (dose, duration, and adherence unknown), but neither regimen improved[e-ijas.org] Old age ( 65 years), septicemia or shock, renal failure, and a neutrophil count 0.1 10 9 /L have been consensually accepted as poor prognostic factors.[ncbi.nlm.nih.gov] Various limits are given; e.g., absolute neutropenia may exist when the total is less than 1700 cells/mm 3 regardless of the percentage, whereas relative neutropenia may exist[medical-dictionary.thefreedictionary.com] Affected patients typically experience severe neutropenia within several weeks to several months after first exposure to a drug, and mortality is 5%.[ncbi.nlm.nih.gov]

    Missing: CTCAE with
  • Typhlitis

    Abstract The authors report the case of an HIV-infected patient who presented with typhlitis as a complication of typical influenza.[ncbi.nlm.nih.gov] A definition of typhlitis required CT confirmation of inflammation of the cecum, according to CTCAE version 4.03 along with clinical symptoms.[bloodjournal.org] […] origin Chronic diarrhea of unknown origin (disorder) Chronic diarrhoea Chronic diarrhoea of infants AND/OR young children Chronic diarrhoea of unknown origin Chronic non-specific[averbis.com] EPrWl 15 OFF LABEL I 24B Fort Myers News-Press, Sunday, March 5, 1978 Regents board to consider policy some colleges say favors FSU, UF II ... 3?[newspapers.com] Axial and coronal CT images of the lower abdomen demonstrate thickening of the wall of the cecum, nodularity of the lumen and pericolonic stranding consistent with typhlitis[learningradiology.com] It is a common cause of right lower abdominal pain, loose stools and low grade fever in patients on intensive chemotherapy, or in those with low immunity and low white blood[abdopain.com] Laboratory tests Neutropenia is confirmed through a complete blood cell (CBC) count, which is a critical test.[symptoma.com] In our experience early recognition of typhlitis and rapid recovery of the neutrophils are the most important determinants of the results of surgical and/or medical approaches[ncbi.nlm.nih.gov] Before institution of alemtuzumab therapy, full blood cell count disclosed the following: hemoglobin 12.7 g/dL, white blood cell count 88 10 9 /L (absolute neutrophil count[haematologica.org] We recently observed a case of particular interest as the patient with T cell prolymphocytic leukaemia treated with alemtuzumab, exhibited symptomatic reactivation of CMV infection[ncbi.nlm.nih.gov]

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  • Idiopathic Neutropenia

    This prospective study confirmed the existence of an association between H. pylori infection and CIN, suggesting the screening for H. pylori infection and eradicating bacterium[ncbi.nlm.nih.gov] The nature of such an inflammation is unknown.[ncbi.nlm.nih.gov] All patients received rhG-CSF, 5 micrograms/kg subcutaneously, as a single daily dose until an absolute neutrophil count (ANC) above 1.5 x 10(9)/L was observed.[ncbi.nlm.nih.gov] These findings provide additional evidence for the existence of an unrecognized low-grade chronic inflammatory process in NI-CINA patients and coroborate our previously reported[ncbi.nlm.nih.gov] Treating a low white blood cell count A blood test can tell you if your white blood cell count is low.[nhs.uk] Neutrophil marrow cellularity was determined from neutrophil-normoblast ratios in marrow sections and ferrokinetic estimation of normoblasts.[ncbi.nlm.nih.gov] The absolute number of blood NK cells was reduced, and a diagnosis of nonimmune chronic idiopathic neutropenia of adult was made.[ncbi.nlm.nih.gov] All these findings are suggestive of the existence of an unrecognized low-grade chronic inflammatory process which may be involved in the pathogenesis of the disorder.[ncbi.nlm.nih.gov] Homepage Rare diseases Search Search for a rare disease Adult idiopathic neutropenia Disease definition A rare acquired immunodeficiency disease characterized by adult-onset absolute[orpha.net] Neutropenia International Registry Idiopathic Neutropenia The term ‘idiopathic neutropenia’ describes various types of neutropenia that may occur at any point in life for unknown[depts.washington.edu]

    Missing: CTCAE Cecum with
  • Refractory Anemia with Excess Blasts

    He was subsequently found to have advanced HIV infection.[ncbi.nlm.nih.gov] Dictionary for Regulatory Activities (MedDRA), and will be summarized by worst grade according to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE[clinicaltrials.gov] Terminated NCT00363025 Phase 3 Idarubicin versus daunorubicin 22 Amifostine in Treating Patients With Advanced Myelodysplastic Syndrome Unknown status NCT00003123 Phase 2[malacards.org] All RAEBt patients showing peripheral blood (PB) blasts of or 5% were re-classified as RAEB by the WHO classification.[ncbi.nlm.nih.gov] […] appendix (small finger-shaped pouch at the end of the first part of the large intestine). appendix listen (uh-PEN-dix) A small, fingerlike pouch that sticks out from the cecum[cancer.gov] 2015 ICD-9-CM Diagnosis Code 238.73 High grade myelodysplastic syndrome lesions 2015 Billable Thru Sept 30/2015 Non-Billable On/After Oct 1/2015 ICD-9-CM 238.73 is a billable[icd9data.com] Not only the neutrophil count, but also the platelet count increased soon after initiation of the G-CSF therapy; both counts became normal on the fifth day of the G-CSF therapy[ncbi.nlm.nih.gov] […] anemia with ringed sideroblasts; RCMD refractory cytopenia with multilineage dysplasia; RAEB refractory anemia with excess blasts; del(5q) 5q- syndrome All MDS must not have absolute[surgpathcriteria.stanford.edu] No lab test is absolutely confirmatory for MDS.[clinicaladvisor.com] Myelodysplastic disorders in the cat are a form of marrow failure often associated with infection with feline leukemia virus.[ncbi.nlm.nih.gov]

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  • Hemolytic Uremic Syndrome

    To this end, one of the known complications of pH1N1 influenza A infection is secondary bacterial infections.[doi.org] NCI Common Terminology Criteria for Adverse Events(CTCAE) V3.0 凝固 Page 10 No: 06005 血栓性微小血管障害(例: 血栓性血小板減少性紫斑病[TTP]または溶血性尿毒症症候群[HUS] Thrombotic microangiopathy (e.g., thrombotic[osaka-med.ac.jp] Although the pathogenesis is unknown, available evidence strongly suggests that endothelial cell damage is necessary.[ncbi.nlm.nih.gov] […] which case localized gas gangrene may provide an important sign) but may also arise as gut infection in individuals exposed to sheep or individuals with carcinoma of the cecum[emedicine.medscape.com] Despite taking the standard recommended dose of eculizumab for an adult, this aHUS patient developed a low-grade thrombotic microangiopathy on biopsy within months of renal[ncbi.nlm.nih.gov] […] being proportional to the white-cell count.[dx.doi.org] […] platelet-neutrophil complexes.[doi.org] What Lab Results Are Absolutely Confirmatory?[clinicaladvisor.com] […] sequencing of genes with known mutations causative of atypical HUS found that she was homozygous for the Complement Factor H H3 haplotype and heterozygous for a variant of unknown[ncbi.nlm.nih.gov] […] good repair, clean surfaces, dustless cleaning methods [2], Single-service articles, storage, dispensing [1], Rooms clean, lockers provided, facilities clean [1]95Fisher Grade[safetables.org]

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