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  • Febrile Neutropenia

    Polymicrobial infection in patients with cancer: an underappreciated and underreported entity. Clin Infect Dis. 2007;45:228-233. 29.[] The definition of FN was used the criteria of CTCAE (ver. 4.0).[] All studies included people with cancer with fever of unknown origin and excluded people with microbiological documented infections.[] The patient's clinical manifestations resolved 5 days later.[] The prevention of oral mucositis is essential requiring standard dental care, gentle tooth brushing and chlorexidine mouth rinses.Is neutropenic diet prohibiting uncooked[] The proportion of severe adverse events (CTC-NCI grades 3/4) was low in both periods (4 and 1%).[] Neutropenia is defined as an absolute neutrophil count (polymorphonuclear cells plus band forms) of 500/ml or less.[] […] available electronic medical record data between January 2009 and December 2011, we examined cases of chemotherapy -induced neutropenia reported in our hospital using the CTCAE[] In the USA, a mortality rate associated with grade 3 and 4 neutropenia ranging from 3.4 % to 10.5% with an overall mortality ranging from 6.8% to 9.5% was reported Ozguler[] It is defined as a temperature higher than 38.3 degrees Celsius or 100.5 degrees Farenheit in the presence of any severity of neutropenia, which is typically an absolute neutrophil[]

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  • Cyclic Neutropenia

    Abstract Atraumatic Clostridium septicum infection is rare in infancy and childhood and is associated with a high mortality rate.[] Abstract Fever of unknown origin (FUO) is the diagnosis associated with a variety of infectious, neoplastic, or rheumatic/inflammatory disorders.[] Epidemiology Most patients present before the age of 5 years: 32% are 27% are between ages 1 and 5 years.[] They demonstrate that regular tooth care and professional dental treatment can prevent progressive periodontal breakdown but that neglecting oral hygiene soon leads to periodontal[] Further work up of the patient for high grade fever and occasional leukopenias revealed the diagnosis of cyclic neutropenia.[] Cyclic therapy with G-CSF (5 micrograms/kg/d s.c. for 1 week every 21 d) maintained peripheral neutrophil count above the normal range, reduced the incidence of severe infections[] The authors hypothesized that congenital neutropenia is also due to mutations of neutrophil elastase.[] When G-CSF therapy was discontinued, the leukocyte and absolute neutrophil counts again declined.[] Because of its rarity, location, and an unknown association with CN, we found this case worthwhile to publish.[] Grade 1 mobility was noticed with tooth 36 and 46.[]

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  • Idiopathic Neutropenia

    This prospective study confirmed the existence of an association between H. pylori infection and CIN, suggesting the screening for H. pylori infection and eradicating bacterium[] The nature of such an inflammation is unknown.[] All patients received rhG-CSF, 5 micrograms/kg subcutaneously, as a single daily dose until an absolute neutrophil count (ANC) above 1.5 x 10(9)/L was observed.[] These neutropenia precautions include: Good hygiene, including frequent hand washing and good dental care, such as regular tooth brushing and flossing Avoiding contact with[] These findings provide additional evidence for the existence of an unrecognized low-grade chronic inflammatory process in NI-CINA patients and coroborate our previously reported[] Treating a low white blood cell count A blood test can tell you if your white blood cell count is low.[] Neutrophil marrow cellularity was determined from neutrophil-normoblast ratios in marrow sections and ferrokinetic estimation of normoblasts.[] The absolute number of blood NK cells was reduced, and a diagnosis of nonimmune chronic idiopathic neutropenia of adult was made.[] All these findings are suggestive of the existence of an unrecognized low-grade chronic inflammatory process which may be involved in the pathogenesis of the disorder.[] Homepage Rare diseases Search Search for a rare disease Adult idiopathic neutropenia Disease definition A rare acquired immunodeficiency disease characterized by adult-onset absolute[]

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  • Lymphocytopenia

    infection.[] Lymphopenia was classified according to CTCAE (Common Terminology Criteria for Adverse Events) version 4.[] After cord blood transplantation, CD4( ) lymphocytopenia from unknown causes was observed, and persistent infections with human parvovirus B19 (B19) occurred.[] Comment to Haematologica. 2011;96(8):1221–5 Haematologica April 2012 97: e9-e11; doi: 10.3324/haematol.2011.058669 We read with interest a recent article in Haematologica[] A significant correlation of total leukocyte count and NLCR, but not lymphocyte count, with parasitaemia was found.[] Likewise, the neutrophil-lymphocyte count ratio (NLCR) has been shown a simple promising method to evaluate systemic inflammation in critically ill patients.[] In univariate analysis, subnormal absolute lymphocyte count (ALC) 9 /l; P 0.001), ALC 9 /l (P 0.0002), subnormal absolute monocyte count (AMC) 9 /l (P 0.0003), LMR (P 0.0001[] Background: Idiopathic CD4 lymphocytopenia (ICL) is a rare disorder of unknown etiology.[] The normal absolute lymphocyte count is significantly higher in childhood.[] The cause of this condition remains unknown; these cases may represent a heterogeneous group of disorders.[]

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  • Congenital Neutropenia

    Abstract Severe congenital neutropenia is one of primary immunodeficiency disorders that characterized by severe neutropenia and is associated with severe systemic bacterial infections[] RESULTS: ELANE mutations correlated with more severe periodontal status than the HAX1 or unknown mutations in patients with SCN.[] We present the case of a 5-month old male with congenital neutropenia who developed severe TAH during treatment with granulocyte colony-stimulating factor (G-CSF).[] These neutropenia precautions include: Good hygiene, including frequent hand washing and good dental care, such as regular tooth brushing and flossing Avoiding contact with[] Cumulative incidence (day 90) of acute graft-versus-host disease (GVHD) grade 2-4 was 21%.[] Treating a low white blood cell count A blood test can tell you if your white blood cell count is low.[] These results demonstrate that precursors containing the mutation are selectively lost during myelopoiesis or fail to develop into neutrophils.[] […] Abstract Severe congenital neutropenia is an autosomal recessive disorder characterized by maturation arrest at the promyelocyte/myelocyte phase in the bone marrow, absolute[] Fungal infections may lead to serious complications in immunodeficient patients.[] Deaths were mainly due to sepsis (5 patients, 4/5 not responding to G-CSF, none with G6PC3 mutation).[]

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  • Agranulocytosis

    Treatment of agranulocytosis consists of the immediate and permanent withdrawal of the offending drug and control of the infection with antibiotics.[] High-dose methylprednisolone therapy should thus be considered for patients demonstrating ANA-positive agranulocytosis with an unknown etiology that is refractory to G-CSF[] Pharmacogenomics J. 2017 Oct;17(5):471-478. doi: 10.1038/tpj.2016.32.[] These neutropenia precautions include: Good hygiene, including frequent hand washing and good dental care, such as regular tooth brushing and flossing Avoiding contact with[] He was diagnosed as dengue hemorrhagic fever, grade I because he had hemoconcentration, thrombocytopenia without bleeding and positive IgM dengue antibody On the 5th day,[] Results: At the onset of agranulocytosis, the median administration period of MMI was 33 days, the average white blood cell count was 1 896/μL, and the median neutrophil count[] Evaluation of a peripheral blood smear showed leukopenia with severe absolute neutropenia.[] These neutropenia precautions include: Good hygiene, including frequent hand washing and good dental care , such as regular tooth brushing and flossing Avoiding contact with[] Prevailing low grade fever may progress into a high fever or hypothermia along with rapid breathing, confusion, and body swelling.[] However, the exact incidence and risk factors of this complication in patients with nephrotic syndrome remain unknown.[]

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  • Drug-induced Neutropenia

    However, pneumonia, gastrointestinal and genitourinary infections, but also systemic infections that lead to life-threatening sepsis and substantial morbidity/mortality may[] Discussion AOSD and SS are inflammatory diseases of unknown etiology, which share several clinical characteristics (high-grade fever, neutrophilic urticarial dermatosis and[] In approximately 5% of cases drug-induced agranulocytosis may be fatal.[] These neutropenia precautions include: Good hygiene, including frequent hand washing and good dental care, such as regular tooth brushing and flossing Avoiding contact with[] Because several target antigens of ANCA are expressed on the surface of neutrophils, it was suggested that ANCA might contribute to neutropenia.[] In addition, the delta MNV and delta MNS were respectively correlated well with delta absolute neutrophil counts when neutropenia occurred.[] Two years ago, she had been prescribed oral and injected risperidone (CONSTA ) at another institution (dose, duration, and adherence unknown), but neither regimen improved[] Old age ( 65 years), septicemia or shock, renal failure, and a neutrophil count 0.1 10 9 /L have been consensually accepted as poor prognostic factors.[] Various limits are given; e.g., absolute neutropenia may exist when the total is less than 1700 cells/mm 3 regardless of the percentage, whereas relative neutropenia may exist[] Affected patients typically experience severe neutropenia within several weeks to several months after first exposure to a drug, and mortality is 5%.[]

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  • Filgrastim

    The patient had no significant toxicity to the CyA or the filgrastim and he has not experienced any serious infections or required hospitalization.[] Filgrastim is given an P3 rating for pregnancy which means unknown, that the risk to the fetus cannot be ruled out.[] Secondary mobilization endpoints included peripheral CD34( ) cells/μL on days 4 and 5 of mobilization, adjunctive use of plerixafor, CD34( ) cells/kg collected on day 5, number[] […] activated charcoal and that it may actually increase the risk of tooth decay and staining.[] […] febrile neutropenia, and neutropenia of any grade.[] We describe a 43-year-old woman suffering from myelokathexis, with the absolute neutrophil count ranging between 0.03 and 1.35 x 10(9)/L.[] Efficacy was evaluated by the recovery of absolute neutrophil count following FSK0808 administration based on the duration of neutropenia in patients who received pre- or[] […] among others, is a medication used to treat low blood neutrophils. [1] Low neutrophils may occur with HIV/AIDS, following chemotherapy or radiation poisoning, or be of an unknown[] The donor cells were collected through four aphereses after G-CSF mobilization with 5 micrograms/kg/d for 5 days.[] Outcomes included febrile neutropenia, severe neutropenia, duration of severe neutropenia, time to recovery of absolute neutrophil count, and incidence of bone pain.[]

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  • Pneumonia

    In addition, evidence-based management of other respiratory infections, including tuberculosis, is discussed.[] Furthermore, the causative microorganisms remained unknown.[] In the United States alone, pneumonia kills about 50,000 people a year, mostly adults over 75 and children under 5.[] We, therefore, investigated the association of tooth loss with mortality from pneumonia in a cohort study of Japanese dentists.[] CASE SUMMARY: A 59-year-old man with a history of chronic obstructive pulmonary disease (COPD) presented with dry cough, low-grade fever, and progressive dyspnea.[] We compared and analyzed their age of onset, peripheral blood white blood cell count, liver enzymes, chlamydia trachomatis titers, and chest radiograph scores.[] KEYWORDS: Anti-neutrophil cytoplasmic antibody; Co-trimoxazole; Pneumocystis jirovecii pneumonia; Prophylaxis; Vasculitis[] A second randomized trial (n   580) failed to demonstrate noninferiority of β-lactam monotherapy vs β-lactam plus macrolide combination therapy, with an absolute difference[] Semin Respir Infect . 2002 Sep. 17(3):204-14. [Medline] .[] The type of pneumonia Clinton has is unknown. But walking pneumonia is a very common type of the disease that does not require a hospital stay.[]

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  • Shwachman Syndrome

    Daily injections of 7.5 micrograms/kg/day significantly increased the absolute neutrophil count and he was free from infections.[] The cause of this syndrome is unknown, although autosomal recessive inheritance has been proposed.[] Pancreatic lipase secretion was assessed in 3 patients with steatorrhea and 5 without steatorrhea (73% of the surviving patients) using a sensitive assay which used maximum[] […] development, dental abscesses, cavities and gum problems After cystic fibrosis, SDS is the next most common cause of pancreatic insufficiency, which makes it difficult for[] Two patients with grade IV GVHD died. Three patients had grade II GVHD.[] Neutrophil mobility was significantly defective in the group of patients as a whole (in 12 it was below the lower limit of normal) and in their parents.[] SDBS is a member of a highly conserved protein family of unknown function with putative orthologs in diverse species including archaea and eukaryotes.[] […] time without progressing to myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML); (4) the del(20)(q11) involves the minimal region of deletion typical of MDS/AML; (5)[] Although the SBDS gene mutated in this disorder is highly conserved in Archaea and all eukaryotes, the function is unknown.[] , Expert Review of Hematology , 5 , 4 , (373) , (2012) .[]

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