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  • Hemangioblastoma

    Established as the leading textbook on imaging diagnosis of brain and spine disorders, Magnetic Resonance Imaging of the Brain and Spine is now in its Fourth Edition.[books.google.ro] Author information 1 Departments of 1 Neurosurgery and. 2 Radiation Oncology, Stanford University School of Medicine, Stanford, California.[ncbi.nlm.nih.gov] Clinical and neuroimaging follow-up was obtained for all patients between 0.5 and 9 years (mean, 4 years) after radiosurgery. Results.[springerlink.com] Therefore, pediatric neuro-oncology was granted its own, book-like section.[books.google.ro] Abstract An effective therapy for multifocal central nervous system hemangioblastoma (CNS HB) is needed. Here, we report a case of multifocal CNS HB.[ncbi.nlm.nih.gov] These lesions are so rarely found arising from peripheral nerves that only four published cases exist in literature today.[ncbi.nlm.nih.gov] None of the VHL gene mutations and chromosome 3p deletion was detected in the tumor.[ncbi.nlm.nih.gov] Federal Republic of Germany Rhoton Anatomy Links Abstract The findings of a 10-year study (1976 to 1986) conducted in southwest Germany on hemangioblastomas (HBL's) of the central[dx.doi.org] None of our patients had significant neurological deterioration after surgery.[ncbi.nlm.nih.gov] Stereotactic radiosurgery is an option for many conditions of the brain, head or neck.[mercy.com]

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  • Primary Central Nervous System Lymphoma

    My life was literally changed overnight by brain tumors.[braintumor.org] […] of Korea. 5 Department of Radiation Oncology, Yonsei Cancer Center, 50-1 Yonsei-ro, Seodaemoon-gu, Seoul, 03722, Republic of Korea. 6 Department of Radiation Oncology, Inha[ncbi.nlm.nih.gov] The authors report a case of post-transplant primary central nervous system lymphoma after liver transplantation that was treated successfully by gamma knife radiosurgery[ncbi.nlm.nih.gov] Clinical Advances in Hematology & Oncology July 2015, Volume 13, Issue 7 Tracy Batchelor, MD, MPH Executive Director Stephen E. and Catherine Pappas Center for Neuro-Oncology[hematologyandoncology.net] […] primary central nervous system lymphoma.[ncbi.nlm.nih.gov] Abstract Primary Central nervous system lymphoma (PCNSL) is most frequently a diffuse large B cell lymphoma (DLBCL), which is confined to the Central nervous system (CNS).[ncbi.nlm.nih.gov] BACKGROUND: Here we describe a case of PCNSL which was located peripherally as a single lesion and showed no evidence of pathological findings of lymphoma at the first biopsy[ncbi.nlm.nih.gov] None had RT as a first-line treatment. One patient had a local relapse and received RT and salvage chemotherapy, without success.[ncbi.nlm.nih.gov] Abstract Classical neurosurgical teaching suggests that corticosteroid administration reduces the diagnostic yield of stereotactic brain biopsy for primary central nervous[ncbi.nlm.nih.gov] Abstract A 45-year-old man who developed brain radionecrosis in the right frontal and left temporoparietal lobes after receiving whole brain radiotherapy and stereotactic radiosurgery[ncbi.nlm.nih.gov]

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  • Atypical Teratoid Rhabdoid Tumor

    Commonly misdiagnosed over the decades as primitive neuroectodermal tumor of the brain, it has dramatically different biological behavior.[ncbi.nlm.nih.gov] As most patients with AT/RT present as infants or young children, radiation therapy has been a less than standard treatment option.[ncbi.nlm.nih.gov] Hernandez L, Zamorano L, Sloan A et al (2002) Gamma knife radiosurgery for renal cell carcinoma brain metastases.[doi.org] , Psycho-Oncology , 22 , 2 , (447-458) , (2012) .[doi.org] Extracranial metastases of the central nervous system tumors are rarely seen.[doi.org] Clinical and morphological features of an apparently unique, biologically aggressive central nervous system tumor in 32 infants and children are presented.[ncbi.nlm.nih.gov] […] report the case of a 4-month-old boy with ATRT with partial resection of his tumor who achieved complete remission using tandem high-dose therapy followed by autologous peripheral[ncbi.nlm.nih.gov] CTX/TOPO PD None None 70 days from day 1, DOD March 1989–May 2004 13 Chemotherapy NED Local prior to HDCT CTX/TOPO NED None None 862 days from day   1, alive, NED Gardner[ncbi.nlm.nih.gov] There was inadequate response to the antituberculosis therapy; so we performed stereotactic brain biopsy.[ncbi.nlm.nih.gov] […] rhabdoid tumor of the kidney who received an intensive multimodal approach combining surgical resection, intrathecal chemotherapy, and high-dose chemotherapy with autologous peripheral[ncbi.nlm.nih.gov]

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  • Glioblastoma Multiforme

    The subcortical gray matter–white matter pattern of nodule distribution reflects the filtration of intravascular particulate material in the region, where vessels branch and[doi.org] Glioblastomas belong to a group of brain tumours known as gliomas, as they grow from a type of brain cell called a glial cell.[thebraintumourcharity.org] The median survival in the radiation-plus-temozolomide group was 14.6 months compared to 12.1 months in the radiation-alone group.[web.archive.org] KEYWORDS: Dural metastasis; Glioblastoma multiforme; High grade glioma; Stereotactic radiosurgery[ncbi.nlm.nih.gov] This means that specialist in Neurology, Neuro-Surgery, Radiation Oncology, Neuro-Radiology, Pathology and Neuro-Oncology are all involved when formulating your treatment[web.archive.org] Chicago, IL: Central Brain Tumor Registry of the United States; 1997–2001. Google Scholar 2. Landis SH, Murray T, Bolden S, Wingo PA: Cancer statistics .[doi.org] We report a case of massive PE treated with systemic thrombolysis in a patient with recent neurosurgery for an intracranial neoplasm.[ncbi.nlm.nih.gov] World Health Organization Classification of Tumors of the Nervous System From: Kleihues P, Cavenee WK, eds.[web.archive.org] Cranial computed tomography (CT) and magnetic resonance imaging (MRI) were obtained, showing a heterogeneous lesion in the cingulate gyrus, with peripheral and central areas[ncbi.nlm.nih.gov] None of the evaluated socioeconomic, environmental and occupational factors were associated with long-term survival.[ncbi.nlm.nih.gov]

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  • Central Neurocytoma

    Compared with other brain tumor (NCN), Patients with CN (CNs) were more likely to be female, young, and non-white race. Surgery was the primary treatment of CN.[ncbi.nlm.nih.gov] One-mortality case due to radiation necrosis and one radiation-induced malignancy occurred.[ncbi.nlm.nih.gov] KEYWORDS: Central neurocytoma; Gamma Knife; Linear accelerator; Radiosurgery; Stereotactic radiosurgery[ncbi.nlm.nih.gov] Pediatric Hematology/Oncology § Neurology Radiation Oncology ¶ Neurosurgery # Radiology, Boston Children ’s Hospital ** Department of Pathology, Brigham and Women’s Hospital[journals.lww.com] J Neuropathol Exp Neurol 23:692–705 Google Scholar Rubinstein LJ (1972) Tumors of the central nervous system.[doi.org] […] histological grading system [ 25 , 52 ].[doi.org] […] choroid plexus Atypical teratoid rhabdoid tumor Autoimmune thrombocytopenia Autosomal dominant macrothrombocytopenia Autosomal thrombocytopenia with normal platelets Benign peripheral[se-atlas.de] None of the previous cases with dissemination had histological atypia but most did have a high MIB-1 labeling index (MIB-1 LI).[ncbi.nlm.nih.gov] Although stereotactic radiosurgery (SRS) is effective for central neurocytoma (CN), the long-term outcome of SRS remains unclear.[ncbi.nlm.nih.gov] Scheithauer , The New WHO Classification of Brain Tumours , Brain Pathology , 3 , 3 , (255-268) , (2008) .[doi.org]

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  • CNS Metastasis

    […] people a year, a far greater incidence than primary brain tumors.[books.google.com] Treatment Radiation therapy should be given to symptomatic areas and to sites of bulky disease. Radiation is the best treatment for focal leptomeningeal nodules.[rtnotes.wikidot.com] In unresectable brain metastases, stereotactic radiosurgery and whole brain radiotherapy warrant consideration in up to 2-3 metastases.[ncbi.nlm.nih.gov] This case adds to the repertoire of neurotoxicity of systemic MTX monotherapy.[n.neurology.org] They analyzed the peripheral blood for glioblastoma cells by immunohistochemical staining for GFAP in 141 patients with glioblastoma.[omicsonline.org] , Conflict of Interest: None DOI: 10.4103/0019-509X.76632 How to cite this article: Rai B, Pandey A K, Aggarwal R, Dimri K.[indianjcancer.com] The therapy for a single brain metastasis remains either surgery or radiosurgery, with conflicting information as to the benefit of prior whole-brain radiation.[ncbi.nlm.nih.gov] Dr Van Meir is an active member of the International Neuro-Oncology community and served on the Board of Directors of the Society for Neuro-Oncology from 2004-2008.[books.google.es] , Conflict of Interest: None DOI: 10.4103/0377-4929.138719 [Figure 1] , [Figure 2] [Table 1] , [Table 2][ijpmonline.org] , stereotactic radiosurgery with or without whole-brain radiotherapy,” Dr.[ascopost.com]

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  • Meningioma

    Television icon Mary Tyler Moore is undergoing surgery today to remove a tumor from the protective lining around her brain.[web.archive.org] The controversy today involves the efficacy of postoperative radiation therapy.[ncbi.nlm.nih.gov] KEYWORDS: Cyberknife; Meningiomas; fractionated stereotactic radiotherapy; stereotactic radiosurgery[ncbi.nlm.nih.gov] & GROW School for Oncology, Maastricht University Medical Centre, The Netherlands. 3 Department of Radiation Oncology, Catalan Institut of Oncology, Hospital Germans Trias[ncbi.nlm.nih.gov] General Information About Adult Central Nervous System Tumors Key Points An adult central nervous system tumor is a disease in which abnormal cells form in the tissues of[cancer.gov] PMID 2888021 - Russell DS, Rubinstein LJ Pathology of Tumors of the Nervous System,. 1989.[atlasgeneticsoncology.org] Sometimes cancerous tumours called malignant peripheral nerve sheath tumours may grow along the nerves.[cancer.ca] […] survival rate in that group was not related to tumor size but was associated with a younger age (p 0.01) and treatment after 1980 with innovative technologies (p 0.002); none[ncbi.nlm.nih.gov] Identical nerve sheath tumors are also seen on spinal roots and the peripheral nerve.[web.archive.org] 10 65 II 1 66 70 Resection 2, RT/temozolomide None 7.0 Ongoing None 11 42 Unknown 1 59 80 Resection 2; RT; SRS None 7.0 Toxicity None 12 19 I 1 20 90 Resection; SRS; RT Temozolomide[ncbi.nlm.nih.gov]

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  • Brain Irradiation

    Concerns of radiation effects on the brain tissue and neurocognitive function and quality of life increase as survival of patients treated for brain tumors improves.[ncbi.nlm.nih.gov] METHODS: Ninety-eight patients receiving radiosurgery alone were retrospectively compared to 50 patients receiving radiosurgery plus whole-brain irradiation for local control[ncbi.nlm.nih.gov] Research and Chairman of Radiation Oncology at Henry Ford Health System in Detroit.[journals.lww.com] BACKGROUND: Neurotoxicity after whole-brain irradiation remains a major problem in the treatment of primary central nervous system lymphoma (PCNSL).[ncbi.nlm.nih.gov] However, estimated radiation doses to peripheral areas of the body were 1.9 times higher with IMRT than with 3D-CRT.[ncbi.nlm.nih.gov] None of the other studied variables had prognostic significance.[ncbi.nlm.nih.gov] Given the significant benefit of stereotactic radiosurgery for the treatment of 1 to 3 brain metastases, we evaluated the use of stereotactic radiosurgery boost after whole[ncbi.nlm.nih.gov] BACKGROUND: Patients with melanoma metastatic to the central nervous system (CNS) have an extremely poor prognosis and appear to benefit little from WBI.[ncbi.nlm.nih.gov] None of the medications work very well, and all of them have serious side effects. Currently, there is no approved cure.[nortonhealthcare.com] After undergoing resection, high-dose chemotherapy was administered consisting of topotecan, melphalan, and cyclophosphamide with autologous peripheral stem cell rescue followed[ncbi.nlm.nih.gov]

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  • Ependymoma

    Ependymomas can grow in different parts of the brain, and symptoms may relate to the area of the brain that is affected: A tumour of the frontal lobe of the brain may cause[melissasfightingfund.co.uk] Proton-beam radiation therapy (PRT) is used at some centers in an effort to decrease long-term toxicity.[ncbi.nlm.nih.gov] Radiosurgery resulted in significant brainstem toxicity and one death (median dose, 18 Gy).[ncbi.nlm.nih.gov] This was a prospective, multicenter Phase II trial conducted through the Children's Oncology Group (ClinicalTrials.gov Identifier NCT01462695 ).[ncbi.nlm.nih.gov] Abstract We present the first case of central neurocytoma with a component suggesting ependymal-like differentiation as an unclassified glioneuronal tumor.[ncbi.nlm.nih.gov] Abstract Superficial siderosis of the central nervous system is a syndrome caused by deposition of hemosiderin in the subpial layers of the central nervous system, occurring[ncbi.nlm.nih.gov] Due to the presence of giant cells, the differential diagnosis of other primary neoplasias at that site were considered, including paraganglioma, malignant peripheral nerve[ncbi.nlm.nih.gov] None of the patients got further treatment (chemotherapy, radiation therapy, or second surgery).[ncbi.nlm.nih.gov] UPMC neurosurgeons may also treat your ependymoma with stereotactic radiosurgery using the Cyberknife and other linear accelerator-based systems.[upmc.com] Commonly dedicated operative meetings are instead attended by around 20-25 people generally having activities in dedicated projects of pediatric oncology, radiotherapy, neurosurgery[siope.eu]

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  • Radiation Therapy

    The forms of ionizing radiation relevant to the treatment of cancer are X-rays, gamma rays, and particulate radiation beams.[britannica.com] CONCLUSIONS: Optimal setups for brain treatments with synchrotron radiation micro- and minibeam combs depend on the brain displacement due to cardiosynchronous pulsation.[ncbi.nlm.nih.gov] Radiation therapy is the use of high-energy radiation to damage cancer cells' DNA and destroy their ability to divide and grow.[radiologyinfo.org] KEYWORDS: Cyberknife; Inverse planning; Stereotactic radiation therapy; Stereotactic radiosurgery[ncbi.nlm.nih.gov] The Department of Radiation Oncology is part of Heidelberg University's Faculty of Clinical Medicine .[umm.uni-heidelberg.de] PURPOSE: To examine safety and efficacy of stereotactic body radiation therapy (SBRT) for centrally located hepatocellular carcinoma (CL-HCC).[ncbi.nlm.nih.gov] This paper presents a magnetic position tracking system for radiation therapy. The proposed system uses only four transmitting coils and an implantable transponder.[ncbi.nlm.nih.gov] BACKGROUND: Schwannomas and meningiomas are relatively common tumors of the nervous system.[ncbi.nlm.nih.gov] The rapid onset of unilateral macular atrophy without peripheral retinopathy after radiation has rarely been described. METHODS: A case report and literature review.[ncbi.nlm.nih.gov] Five patients developed grade 2 acute radiation dermatitis, and none developed grade 2 or higher late radiation dermatitis.[ncbi.nlm.nih.gov]

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