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2,893 Possible Causes for A,, Mycobacterium, efflux, protein, Tuberculosis

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  • Protein Losing Enteropathy

    Disseminated mycobacterium avium complex (MAC) causing protein-losing enteropathy (PLE) due to intestinal lymphangiectasia (IL) in a non-HIV immunocompromised state is extremely[ncbi.nlm.nih.gov] Inflammatory bowel disease (Chron's disease), intestinal tuberculosis and intestinal ulcers secondary to non-steroidal anti-inflammatory drugs are the main differential diagnosis[ncbi.nlm.nih.gov] […] increased fecal loss of serum protein, especially albumin, causing hypoproteinemia. protein-losing enteropathy Gastroenterology A condition characterized by excess transmucosal efflux[medical-dictionary.thefreedictionary.com] She also had severe protein C and protein S depletion from GI loss which caused extensive thrombosis.[ncbi.nlm.nih.gov] She had been diagnosed with AIDS and disseminated Mycobacterium avium complex (MAC) infection at age 26.[ncbi.nlm.nih.gov]

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  • Parainfluenza Virus

    So far, PIV5 has been used to develop vaccines against influenza virus, respiratory syncytial virus, rabies virus, and Mycobacterium tuberculosis, demonstrating its ability[ncbi.nlm.nih.gov] Non-aliquoted 55 CE FEP PCR Only B57-FEP-CE MTC-FEP PDF Mycobacterium tuberculosis complex ( M. tuberculosis, M. bovis, M. bovis BCG, M. africanum, M. microti, M. canetti,[pcrdiagnostics.eu] Specifically, HPIV3 activated the NLRP3/ASC inflammasome by TLR2 activation and potassium efflux.[ncbi.nlm.nih.gov] M protein (ML305A) has a VLP formation ability similar to that of wild-type M protein.[ncbi.nlm.nih.gov] The crystal structure of the F protein (prefusion form) of the paramyxovirus parainfluenza virus 5 (PIV5) WR isolate was determined.[ncbi.nlm.nih.gov]

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  • Toxoplasma Gondii

    This will be achieved by focusing on the macrophage response against two intracellular pathogens, the human etiologic agent of tuberculosis, Mycobacterium tuberculosis and[ncbi.nlm.nih.gov] […] cleavage and release in response to T. gondii infection, without affecting the release of TNF-α, and indicated a role for the inflammasome sensor NLRP3 and for potassium efflux[ncbi.nlm.nih.gov] Toxoplasma gondii deploys many effector proteins in order to hijack and manipulate host cell signaling pathways, allowing parasite colonization, subversion of immune responses[ncbi.nlm.nih.gov] It contained complimentary sequences to "signature genes" of T. gondii, Mycobacterium tuberculosis, M. chelonae, and M. fortuitum.[ncbi.nlm.nih.gov] In recent years, coinfection of tuberculosis (TB) and parasitosis in humans is an emerging problem in coendemic areas, which has been increasingly highlighted in developing[ncbi.nlm.nih.gov]

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  • Brucella Melitensis

    EMP2, ST8SIA4, HCP5 and FRMD5 known to be involved in pathogenesis of Mycobacterium tuberculosis.[ncbi.nlm.nih.gov] Genome analysis revealed multiple virulence determinants and efflux pumps.[ncbi.nlm.nih.gov] Eighty-eight immunoreactive protein spots from B. melitensis M5 were identified by Western blotting and were assigned to sixty-one proteins by mass spectrometry, including[ncbi.nlm.nih.gov] […] melitensis in the Middle East beside reports on antibiotic resistance strains, especially against rifampin, which may literally lead to an increase in resistant strains of Mycobacterium[ncbi.nlm.nih.gov] Mariani et al ( 17 ) investigated the expression of 14 genes in Mycobacterium tuberculosis H37Rv in both medium and macrophages.[spandidos-publications.com]

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  • Francisella Tularensis

    Several Q compounds are also effective against Mycobacterium tuberculosis, in which a second target has also been implicated, in addition to IMPDH.[ncbi.nlm.nih.gov] Granulomatous pleuritis, diagnosed by pleural biopsy, is rarely caused by disease processes other than tuberculosis.[ncbi.nlm.nih.gov] Genes encoding an efflux system (emrA2 cluster of genes), siderophore (fsl operon), acid phosphatase, LPS synthesis, polyamine synthesis, and citrulline ureidase were all[ncbi.nlm.nih.gov] Bacterial outer membrane proteins (OMPs) are involved in various virulence processes, including protein secretion, host cell attachment, and intracellular survival.[ncbi.nlm.nih.gov] - IglA, IglB and IglC, and a fusion protein (IglABC) comprising immunodominant epitopes of IglA, IglB, and IglC downstream of different Francisella promoters, including the[ncbi.nlm.nih.gov]

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  • Phenothiazine

    Among the all '22' compounds screened for in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv (Mtb), three analogs 5c, 5l and 5o were found to be[ncbi.nlm.nih.gov] […] susceptible and resistant strains of M. tuberculosis.[ncbi.nlm.nih.gov] […] of the sensitivity of the above parasites to phenothiazines, efflux pumps may play a role in emerging antibiotic resistance of these organisms.[ncbi.nlm.nih.gov] A new family of protein farnesyltransferase inhibitors, based on a phenothiazine scaffold, was designed and synthesized.[ncbi.nlm.nih.gov] In this work, the molecular recognition of methylene blue by two globular proteins, hemoglobin and lysozyme was characterized by employing fluorescence, circular dichroism[ncbi.nlm.nih.gov]

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  • Morus

    Mycobacterium tuberculosis (Mtb) protein tyrosine phosphatases A and B (PtpA and PtpB) have been recognized as potential molecular targets for the development of new therapeutic[ncbi.nlm.nih.gov] […] exhibited a poor permeability and predominantly traversed Caco-2 cells via passive diffusion; yet, the permeation of OXY across Caco-2 cells was much more rapid and involved efflux[ncbi.nlm.nih.gov] An organic layer prepared from the Chinese crude drug 'Sang-Bai-Pi' (Morus root bark) was studied in order to identify the inhibitory compounds for protein tyrosine phosphatase[ncbi.nlm.nih.gov] Compounds 1 3 showed potent mixed-type enzyme inhibition against protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase.[ncbi.nlm.nih.gov] […] strategies against tuberculosis (TB).[ncbi.nlm.nih.gov]

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  • Enoxacin

    DNA gyrase GyrA/GyrB: IC 50 14 µM; Mycobacterium tuberculosis DNA gyrase GyrB/GyrA A83S, S84A, I85V, F96W and P101M mutant: IC 50 16 µM pK Werte : pK a : 6.04 (Predicted)[scbt.com] Substrate of NorA, an energy dependent drug efflux pump in Staphylococcus aureus. Expression of NorA is responsible for some drug resistant infections.[sigmaaldrich.com] TAR RNA-binding protein 2 (TRBP).[ncbi.nlm.nih.gov] Compared with its paired pretherapy isolate G48, this mutant had several alterations in outer membrane proteins including a complete loss of the major porin protein OprF and[ncbi.nlm.nih.gov] Furthermore, primary prostate carcinomas displayed normal levels of TRBP protein.[ncbi.nlm.nih.gov]

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  • Pleurisy

    A case of tuberculous pleurisy due to Mycobacterium fortuitum in a 47-year-old woman with chronic granulocytic leukemia is described.[ncbi.nlm.nih.gov] Notably, despite latent tuberculosis treatment, active tuberculosis was not prevented.[ncbi.nlm.nih.gov] […] responsible for these phenomena probably are (1) a selective block to glucose transport from blood to pleural fluid, (2) enhanced glucose use by rheumatoid pleura, and (3) an efflux[ncbi.nlm.nih.gov] Many studies reported that interferon-γ-induced protein of 10kDa (IP-10) plays a role in diagnosing tuberculous pleurisy, but with considerable variance of results.[ncbi.nlm.nih.gov] The T lymphocyte-mediated immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy is unknown.[ncbi.nlm.nih.gov]

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  • Brucella Suis

    […] other hand, NK cell activity is impaired in patients with acute brucellosis, and recently it was demonstrated that human NK cells mediate the killing of intramacrophagic Mycobacterium[ncbi.nlm.nih.gov] Our results show that B. suis harbors two functional RND efflux pumps that may contribute to virulence.[ncbi.nlm.nih.gov] The purified recombinant proteins were examined for their binding activity with antiserum.[ncbi.nlm.nih.gov] Selective expansion of human γΔ T cells by monocytes infected with live Mycobacterium tuberculosis . J. Clin. Invest. 87 : 729 Young, J. L., H. Goodall, H.[jimmunol.org] Without this exemption, it would be required to implement a system of veterinary checks for tuberculosis and brucellosis , for each bovine animal exported from its region.[it.bab.la]

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