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142 Possible Causes for Acetylase,, Arylamine

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  • Dimethyl Sulfoxide

    IC50 : HII4E cells : IC 50 199 µg.mL-1 (mouse) Ki Data : Choline acetylase: K i 25 mM (rat) pK Values : pK a : -4.54 (Predicted) For Research Use Only.[] Notably, the arylamine reactants also acted as indispensable catalysts to promote enamine formation. X. Geng, X. Wu, P. Zhao, J. Zhang, Y.-D. Wu, A.-X. Wu, Org.[] IC50 : HII4E cells : IC 50 199 µg/ml (mouse) Ki Data : Choline acetylase: K i 25000000 nM (Rattus norvegicus) For Research Use Only.[]

  • Shigella Flexneri

    Clark CA, Beltrame J, Manning PA (1991) The oac gene encoding a lipopolysaccharide O-antigen acetylase maps adjacent to the integrase-encoding gene on the genome of Shigella[] Structure of arylamine N -acetyltransferase reveals a catalytic triad . Nature Struct. Biol. 7 , 560–564 (2000) 19. Kitadokoro, K. et al.[]

  • Curcumin

    ., is a histone acetyltransferase inhibitor would supply a new window to understand further the mol. mechanism of histone acetylase inhibitors (HAI) in cancer and neural stem[] Chung, Curcumin inhibited the arylamines N-acetyltransferase activity, gene expression and DNA adduct formation in human lung cancer cells (A549).[] Chung, Curcumin decreases the DNA adduct formation, arylamines N-acetyltransferase activity and gene expression in human colon tumor cells (colo 205).[]

  • Malignant Neoplasm of Urinary Bladder

    […] agents in hair dyes might be arylamines ( 9 , 10 ) .[] To assess arylamine exposure, levels of arylamine–hemoglobin adducts of nine selected alkylanilines (2,3-dimethylaniline [2,3-DMA], 2,4-DMA, 2,5-DMA, 2,6-DMA, 3,4-DMA, 3,5[] Non-smoking related arylamine exposure and bladder cancer risk.[]

    Missing: Acetylase
  • Sulfonamide

    […] that lack the arylamine group, and may therefore safely take non-arylamine sulfonamides.[] The immunogenicity of sulfonamide antimicrobials may be due to the presence of an arylamine group at the N4 position of the sulfonamide molecule.[] ., an N-containing ring attached to the N1 nitrogen of the sulfonamide group and an arylamine group at the N4 position), and only two agents (amprenavir and fosamprenavir)[]

    Missing: Acetylase
  • Sulfasalazine

    Arylamine N-acetyltransferase 1 NAT1*14A Not Available G A T A C A ADR Inferred Increased risk of Sulfapyridine dose related adverse effects, including skin rash.[] METHODS: Arylamine N-acetyltransferase 1 (NAT1) and arylamine N-acetyltransferase 2 (NAT2) genotypes were determined in 266 AS patients who received SSZ treatment and 280[] Details Arylamine N-acetyltransferase 1 NAT1*14B Not Available G A ADR Inferred Increased risk of Sulfapyridine dose related adverse effects, including skin rash.[]

    Missing: Acetylase
  • Aminoglutethimide

    Previous studies have shown that arylamine metabolism by MPO results in protein radical formation.[] Siraki Canadian Journal of Physiology and Pharmacology 2013 91 (3), 228-235 Free Radical Metabolites in Arylamine Toxicity Arno G.[] HL-60 cells contain abundant amounts of myeloperoxidase (MPO), a hemoprotein, which catalyzes one-electron oxidation of arylamines using H2O2 as a cofactor.[]

    Missing: Acetylase
  • Toxic Oil Syndrome

    Genotype analyses were performed to assess the metabolic capacity of phase I [cytochrome P450 1A1 (CYP1A1), CYP2D6] and phase II [arylamine N-acetyltransferase-2 (NAT2), GSTM1[] Abstract The most basic arylamine, aniline, belongs to a class of compounds notorious for inducing allergic and autoimmune reactions.[]

    Missing: Acetylase
  • Mycobacterium Smegmatis

    Arylamine N-acetyltransferase is an enzyme that is conserved in most Mycobacterium spp.[] Abstract MSMEG_0307 is annotated as a transcriptional regulator belonging to the AraC protein family and is located adjacent to the arylamine N-acetyltransferase (nat) gene[]

    Missing: Acetylase
  • Hydralazine

    Details Arylamine N-acetyltransferase 1 NAT1*15 Not Available C T ADR Inferred Associated with systemic lupus erythematosus.[] An update on genetic, structural and functional studies on arylamine N-acetyltransferases in eucaryotes and procaryotes. Human Mol Genet . 2000; 9 : 2435–2441.[] Details Arylamine N-acetyltransferase 1 NAT1*17 Not Available C T ADR Inferred Associated with systemic lupus erythematosus.[]

    Missing: Acetylase

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